The entrance to the Kentucky Science Center with a large circular structure in the foreground.

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Check prices for these dates

This weekend
13 Nov - 15 Nov
Next weekend
20 Nov - 22 Nov

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Our top choices for Louisville Science Center hotels

A grand staircase with a wooden handrail and carpeted steps, leading to an upper floor.

1. Louisville Bourbon Inn

Louisville Bourbon Inn
5.0 star property
Old Louisville, 2.9 km from Louisville Science Center
10.0 out of 10, Exceptional, (25 reviews)
"Absolutely the best B&B we have ever stayed with."
United States
Roy
The price is AED 1,139
AED 1,322 total
includes taxes & fees
15 Nov - 16 Nov
Louisville Bourbon Inn
A wooden staircase with a balustrade leading to a landing.

2. Market Street Inn

Market Street Inn
3.5 star property
2.1 km from Louisville Science Center
9.8 out of 10, Exceptional, (127 reviews)
"Such a lovely stay at the Market Street Inn. A very charming, comfortable and feels like home kind of place. Carol and Steve are just the kindest owners. They were responsive and accommodating and always available if needed. We also loved meeting Lisa, who made breakfast each morning and took care of any housekeeping needs. We felt like we were treated as family and not just guests. The area and location is perfect, SUCH a cute little town. Plenty of restaurants, shops and entertainment within...
United States
Ryan
The price is AED 812
AED 918 total
includes taxes & fees
11 Nov - 12 Nov
Market Street Inn
A grand lobby with ornate columns, plush seating, and a chandelier.

3. The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville, 1.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,475 reviews)
"Beautiful hotel!"
United States
Brianne
The price is AED 380
AED 447 total
includes taxes & fees
24 Nov - 25 Nov
The Brown Hotel
A multi-story hotel with a classic facade, large windows, and a modern glass building adjacent to it.

4. Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
Downtown Louisville, 0.9 km from Louisville Science Center
9.6 out of 10, Exceptional, (520 reviews)
"Excellent location and room!"
United States
Athina
The price is AED 740
AED 871 total
includes taxes & fees
22 Nov - 23 Nov
Hotel Distil, Autograph Collection
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.

5. Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
9.4 out of 10, Exceptional, (2,230 reviews)
"Very very nice property clean well taken care of and great staff would stay again"
United States
James
The price is AED 563
AED 663 total
includes taxes & fees
11 Nov - 12 Nov
Omni Louisville Hotel
A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.

6. Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
Downtown Louisville, 0.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,003 reviews)
"Nice hotel"
United States
Jeanette
The price is AED 419
AED 493 total
includes taxes & fees
24 Nov - 25 Nov
Homewood Suites by Hilton Louisville Downtown, KY
A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.

7. The Grady

The Grady
4.0 star property
Downtown Louisville, 0.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,011 reviews)
"Our stay at The Grady was exceptional and we will definitely be back to stay again soon!!"
United States
Greg
The price is AED 448
AED 527 total
includes taxes & fees
25 Nov - 26 Nov
The Grady
A historic building with a grand entrance, steps leading up to the door, and a sign indicating it is a bed and breakfast.

8. DuPont Mansion Bed & Breakfast

DuPont Mansion Bed & Breakfast
4.0 star property
Old Louisville, 2.8 km from Louisville Science Center
9.6 out of 10, Exceptional, (151 reviews)
"Great staff, clean rooms, amazing historic vibe, and yummy breakfast!"
United States
Chris
The price is AED 525
AED 609 total
includes taxes & fees
22 Nov - 23 Nov
DuPont Mansion Bed & Breakfast
An outdoor terrace with tables and chairs, large windows, and a view of the city skyline at sunset.

9. Tempo By Hilton Louisville Downtown Nulu

Tempo By Hilton Louisville Downtown Nulu
3.5 star property
Phoenix Hill, 2.1 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,156 reviews)
"Great stay!"
United States
Addison
The price is AED 373
AED 439 total
includes taxes & fees
25 Nov - 26 Nov
Tempo By Hilton Louisville Downtown Nulu
A hotel with a prominent sign, a central courtyard with a sculpture, and a dome structure in the background.

10. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
9.4 out of 10, Exceptional, (178 reviews)
"Very good breakfast in hotel lobby restaurant. Extremely nice servers. Reasonably priced."
United States
Paul
The price is AED 539
AED 634 total
includes taxes & fees
23 Nov - 24 Nov
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
A modern building with a sign reading "Stellar Suites" and a crescent moon logo.

11. Stellar Suites

Stellar Suites
4.5 star property
East Market District, 2.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (158 reviews)
"Location was great near meant restaurants and nightspots"
United States
Kevin
The price is AED 400
AED 657 total
includes taxes & fees
17 Nov - 18 Nov
Stellar Suites
A cozy room with a geometric-patterned ceiling, a sofa, and a chair.

12. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville, < 0.1 km from Louisville Science Center
9.4 out of 10, Exceptional, (1,004 reviews)
"Nice modern rooms and excellent cocktails in the bar."
United States
Erick
The price is AED 559
AED 676 total
includes taxes & fees
6 Dec - 7 Dec
21c Museum Hotel Louisville
A covered patio with a stone wall, a glass table, and a bench.

13. Central Park Bed & Breakfast

Central Park Bed & Breakfast
3.5 star property
Old Louisville, 3 km from Louisville Science Center
9.4 out of 10, Exceptional, (101 reviews)
"Amazing stay and hospitality. Will stay again"
United States
Stephen
The price is AED 621
AED 721 total
includes taxes & fees
16 Nov - 17 Nov
Central Park Bed & Breakfast
A spacious indoor area with a large dining table, multiple chairs, a fireplace, and a kitchen area with a bar.

14. Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
Downtown Louisville, 1.2 km from Louisville Science Center
9.2 out of 10, Wonderful, (1,023 reviews)
"Clean and bathrooms are nice I will be staying again."
United States
Trista
The price is AED 350
AED 411 total
includes taxes & fees
30 Nov - 1 Dec
Cambria Hotel Louisville Downtown-Whiskey Row
An outdoor seating area with wicker furniture and a fire pit.

15. Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 0.3 km from Louisville Science Center
9.2 out of 10, Wonderful, (830 reviews)
"Nice stay, bed was comfortable"
United States
Brandi
The price is AED 356
AED 419 total
includes taxes & fees
7 Dec - 8 Dec
Towneplace Suites By Marriott Louisville Downtown
A cozy living room with a fireplace, a black leather sofa, and a patterned rug.

16. Moxy Louisville Downtown

Moxy Louisville Downtown
3.5 star property
Downtown Louisville, 0.9 km from Louisville Science Center
9.2 out of 10, Wonderful, (863 reviews)
"Hotel was super clean and staff were friendly in a great location"
United States
Sheree
The price is AED 415
AED 488 total
includes taxes & fees
25 Nov - 26 Nov
Moxy Louisville Downtown
A modern hotel with a prominent 'Aloft Hotels' sign, multiple floors, and a corner location with a view of the city skyline.

17. Aloft by Marriott Louisville Downtown

Aloft by Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 0.9 km from Louisville Science Center
9.2 out of 10, Wonderful, (1,000 reviews)
"Great clean hotel awesome staff."
United States
Anthony
The price is AED 417
AED 491 total
includes taxes & fees
23 Nov - 24 Nov
Aloft by Marriott Louisville Downtown
An outdoor dining area with a long table and wicker chairs, overhead lighting, and a view of the city.

18. Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
4.0 star property
East Market District, 2.1 km from Louisville Science Center
9.2 out of 10, Wonderful, (1,089 reviews)
"We’ve stayed here a number of times and we love it. Right in the middle of NuLu, it’s the perfect spot."
United States
Jesse
The price is AED 526
AED 618 total
includes taxes & fees
15 Nov - 16 Nov
Hotel Genevieve part of JdV by Hyatt
A modern hotel lobby with a reception desk, seating area, and a large window providing natural light.

19. AC Hotel Louisville Downtown

AC Hotel Louisville Downtown
3.5 star property
East Market District, 2.1 km from Louisville Science Center
9.2 out of 10, Wonderful, (733 reviews)
"Great location, helpful staff, and nice clean rooms,"
United States
Kevin
The price is AED 526
AED 618 total
includes taxes & fees
21 Nov - 22 Nov
AC Hotel Louisville Downtown
A balcony with a view of a river, a bridge, and a cityscape.

20. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville, 0.5 km from Louisville Science Center
9.0 out of 10, Wonderful, (4,490 reviews)
"Great place to stay!!!"
United States
Shun
The price is AED 500
AED 588 total
includes taxes & fees
22 Nov - 23 Nov
Galt House Hotel Trademark Collection by Wyndham
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to Louisville Science Center

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A grand staircase with a wooden handrail and carpeted steps, leading to an upper floor.
Louisville Bourbon Inn
5.0 star property
10.0
Exceptional
25 reviews
View
A wooden staircase with a balustrade leading to a landing.
Market Street Inn
3.5 star property
9.8
Exceptional
127 reviews
View
A grand lobby with ornate columns, plush seating, and a chandelier.
The Brown Hotel
4.5 star property
9.4
Exceptional
1,475 reviews
View
A multi-story hotel with a classic facade, large windows, and a modern glass building adjacent to it.
Hotel Distil, Autograph Collection
4.0 star property
9.6
Exceptional
520 reviews
View
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.
Omni Louisville Hotel
4.0 star property
9.4
Exceptional
2,230 reviews
View

Top Louisville Science Center Hotel Reviews

The Brown Hotel

The Brown Hotel

10/10 Excellent
"Convenient parking garage attached to the hotel, short walking or driving distance from multiple restaurants, friendly and professional staff, and cool, Old Worrld style. Favorite place to stay in Louisville."
JOSHUA 1-night trip
Posted 1 hour ago
The Brown Hotel

Other attractions near Louisville Science Center

A tall wooden baseball bat leaning against a brick building with a sign reading "Hillerich & Brassler Co."

Louisville Slugger Museum

9.2/10 (2,299 reviews)
You can spend an afternoon browsing the exhibits at Louisville Slugger Museum during your travels in Louisville. Amble around the area's riverfront or attend a sporting event.
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Frequently asked questions

What's the area like around Louisville Science Center?
Louisville Science Center is located in an area of Louisville known for its beautiful river views, sporting events, and great live music scene. If you're looking for a convenient place to stay, check out the 292 hotels and other accommodations you'll find within a mile.
What's the best place to stay near Louisville Science Center?
Adjacent to Louisville Science Center, Holiday Inn Express & Suites Louisville Downtown by IHG is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a 24-hour fitness center. Other good choices within a short distance include Galt House Hotel Trademark Collection by Wyndham and Omni Louisville Hotel.
How many hotels can I expect to find close to Louisville Science Center?
Expedia has 292 hotels and other accommodations within a mile from Louisville Science Center.
If I need to cancel the hotel reservation for my stay near Louisville Science Center, will I receive a refund?
Yes, you'll find most hotel room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within a 24-hour period of booking. Add your dates and click on "Search", then filter by "fully refundable" to review the best deals near Louisville Science Center.
Where can I learn more about changing or cancelling my trip in the area near Louisville Science Center?
For more details about picking new dates or cancelling your stay near Louisville Science Center, click here.
What can I see and do near Louisville Science Center?
21c Museum Hotel, Louisville Slugger Museum, and Muhammad Ali Center feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like Belle of Louisville, Whiskey Row, and Big Four Bridge. You can catch a show at Louisville Palace, Derby Dinner Playhouse, and Headliners Music Hall.