Find hotels near Main Street Hyannis, Hyannis from AED 263
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Compare 3,686 hotels close to Main Street Hyannis with room rates, reviews, and availability. Most hotels are fully refundable.

Anchor In Distinctive Waterfront Lodging
Anchor In Distinctive Waterfront Lodging
9.4 out of 10, Exceptional, (1002)
The price is AED 732
AED 1,171 total
includes taxes & fees
10 Jun - 11 Jun

Cape Cod Harbor House Inn
Cape Cod Harbor House Inn
9.2 out of 10, Wonderful, (256)
The price is AED 437
AED 500 total
includes taxes & fees
10 Jun - 11 Jun

SeaCoast Inn
SeaCoast Inn
9.0 out of 10, Wonderful, (634)
The price is AED 511
AED 584 total
includes taxes & fees
10 Jun - 11 Jun

Cape Cod Inn
Cape Cod Inn
8.8 out of 10, Excellent, (431)
The price is AED 400
AED 458 total
includes taxes & fees
10 Jun - 11 Jun

Hyannis Inn
Hyannis Inn
8.6 out of 10, Excellent, (1005)

Hampton Inn & Suites Cape Cod-West Yarmouth
Hampton Inn & Suites Cape Cod-West Yarmouth
8.8 out of 10, Excellent, (1002)
The price is AED 684
AED 783 total
includes taxes & fees
15 Jun - 16 Jun
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Hotels near Other Hyannis Attractions
Hotels near Other Hyannis Attractions

John F. Kennedy Hyannis Museum
4.5/5(137 reviews)
You can spend an afternoon browsing the exhibits at John F. Kennedy Hyannis Museum during your trip to Hyannis. Wander the beautiful beaches and waterfront in this family-friendly area.
Recent reviews of Main Street Hyannis hotels
Recent reviews of Main Street Hyannis hotels

Heritage House Inn on Cape Cod
5/5 Excellent
"We stay in Hyannis for a night before getting the ferry to Nantucket. This is the first place we have stayed that we would stay again. Nicely updated and the staff is very helpful. Great location to the ferry. "
A verified traveler stayed at Heritage House Inn on Cape Cod
Posted 2 days ago
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Hotels near popular Hyannis Attractions
- Hotels near John F. Kennedy Hyannis Museum
- Hotels near Hyannis Harbor
- Hotels near Cape Cod Inflatable Park
- Hotels near Cape Cod Melody Tent
- Hotels near Mayflower Beach
- Hotels near Seagull Beach
- Hotels near Craigville Beach
- Hotels near Harwich Port
- Hotels near West Dennis Beach
- Hotels near Sandy Neck Beach
- Hotels near Cape Cod Rail Trail
- Hotels near Mashpee Commons
- Hotels near Kalmus Beach
- Hotels near Corporation Beach
- Hotels near Barnstable Harbor
- Hotels near Sea Street Beach
- Hotels near Cape Cod Baseball Hall of Fame
- Hotels near Grays Beach
- Hotels near Breakwater Beach
- Hotels near John F. Kennedy Memorial
Other Hotels near Main Street Hyannis, Hyannis
- Cape Cod Hotels
- Martha's Vineyard Hotels
- Chatham Hotels
- Hyannis Hotels
- Falmouth Hotels
- South Yarmouth Hotels
- Oak Bluffs Hotels
- Plymouth Hotels
- Edgartown Hotels
- Dennis Port Hotels
- Sandwich Hotels
- West Yarmouth Hotels
- Brewster Hotels
- Wellfleet Hotels
- Eastham Hotels
- Dennis Hotels
- East Sandwich Hotels
- Orleans Hotels
- Harwich Hotels
- Mashpee Hotels
More Hotel Options in Main Street Hyannis
- Adventure Hotels
- Beach Hotels
- Business Hotels
- Cheap Hotels
- Family Hotels
- Golf Hotels
- Historic Hotels
- Hotel Wedding Venues
- Hotel with a Concierge
- Hotels with Bars
- Hotels with Free Parking
- Hotels with Hot Tubs
- Hotels with WiFi
- Hotels with a Pool
- Hotels with an Indoor Pool
- Hotels with smoking rooms
- Luxury Hotels
- Resorts & Hotels with Spas
- Shopping Hotels
- Winery Hotels
Explore more hotels
- Hyannis Plaza Hotel
- Anchor In Distinctive Waterfront Lodging
- Bayside Resort Hotel
- Doubletree by Hilton Cape Cod - Hyannis
- Ocean Street Inn on Hyannis Harbor
- Hampton Inn & Suites Cape Cod-West Yarmouth
- Cape Cod Harbor House Inn
- Colonial Acres Resort
- Sunbird Cape Cod Resort
- Cape Cod Hyannis Rendezvous'
- Charming Hyannis 3 Bed 2 Bath
- SPACIOUS HOME w/CENTRAL A/C & PRIVATE FENCED IN HALF ACRE YARD. WALK TO ALL..