Find hotels in O Brien, FL from AED 239

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24 Dec - 25 Dec
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25 Dec - 26 Dec
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26 Dec - 28 Dec
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Our top choices for O Brien hotels

Free WiFi, bed sheets
Motel 6 – Lake City, Fl – Medical Center

Motel 6 – Lake City, Fl – Medical Center

Motel 6 – Lake City, Fl – Medical Center
2.0 star property
Lake City
8.2 out of 10, Very Good, (84)
Located in Lake City with easy access to Regal UA Cinema 90 and Lake City Mall, this motel offers convenient amenities including complimentary WiFi, free parking, and 24-hour front desk service.
"Large room, comfortable bed, clean, pet friendly"
United States
D'Ann
The price is AED 225
AED 253 total
includes taxes & fees
28 Dec - 29 Dec
Motel 6 – Lake City, Fl – Medical Center
Lobby
Econo Lodge Live Oak

Econo Lodge Live Oak

Econo Lodge Live Oak
2.0 star property
Live Oak
7.0 out of 10, Good, (277)
In Live Oak, this motel offers complimentary breakfast, WiFi, and parking. Take a refreshing swim in the outdoor pool, then explore nearby Suwannee County Historical Museum and First Federal Sportsplex.
"need grab bars"
United States
Frances and Edward
The price is AED 240
AED 264 total
includes taxes & fees
22 Jan - 23 January 2026
Econo Lodge Live Oak
Exterior
Quality Inn & Suites Live Oak I-10 Exit 283

Quality Inn & Suites Live Oak I-10 Exit 283

Quality Inn & Suites Live Oak I-10 Exit 283
2.5 star property
Live Oak
7.0 out of 10, Good, (518)
Tranquil surroundings create a serene atmosphere at this Live Oak hotel. Enjoy complimentary breakfast, WiFi, and parking while staying in clean, comfortable rooms. Helpful staff ensure a pleasant experience near Suwannee County Historical Museum.
"Staff was very friendly, check-in was super fast, decent room, neat and clean, comfy veds, big towels, breakfast was ok."
United States
Charlotte
The price is AED 314
AED 345 total
includes taxes & fees
25 Dec - 26 Dec
Quality Inn & Suites Live Oak I-10 Exit 283
Lobby
Quality Inn White Springs Suwanee

Quality Inn White Springs Suwanee

Quality Inn White Springs Suwanee
2.5 star property
Live Oak
7.2 out of 10, Good, (618)
Located close to Blue Sink Canoe Launch, this Live Oak hotel offers hiking trails and clean rooms with free WiFi. Enjoy the outdoor pool after exploring Stephen Foster Folk Culture Center State Park. Business travelers appreciate the friendly staff.
"Clean rooms, very friendly staff"
United States
Kristin L
The price is AED 250
AED 275 total
includes taxes & fees
11 Jan - 12 January 2026
Quality Inn White Springs Suwanee
Free daily buffet breakfast
Holiday Inn Express & Suites Live Oak by IHG

Holiday Inn Express & Suites Live Oak by IHG

Holiday Inn Express & Suites Live Oak by IHG
2.5 star property
Live Oak
8.4 out of 10, Very Good, (775)
Located off the interstate, this hotel provides easy access to Suwannee County Historical Museum. Start mornings with free breakfast before exploring First Federal Sportsplex nearby. Clean rooms await after a workout in the fitness center.
"Have stayed here whenever we are in town. Always god stay."
United States
Gregg
The price is AED 443
AED 487 total
includes taxes & fees
11 Jan - 12 January 2026
Holiday Inn Express & Suites Live Oak by IHG
Double Room, Non Smoking | Laptop workspace, free WiFi
High Springs Country Inn

High Springs Country Inn

High Springs Country Inn
2.0 star property
High Springs
8.2 out of 10, Very Good, (17)
Escape to this welcoming motel where free WiFi and parking await. Visit nearby High Springs Civic Center Park and Museum. The 24-hour front desk ensures convenience throughout your small-town adventure.
"Great remodel of a retro motel."
United States
Kathleen
The price is AED 277
AED 312 total
includes taxes & fees
30 Dec - 31 Dec
High Springs Country Inn
Fountain
BlueGem Motel

BlueGem Motel

BlueGem Motel
2.0 star property
High Springs
9.2 out of 10, Wonderful, (394)
This charming motel offers comfortable accommodations in High Springs with complimentary WiFi and parking. Guests appreciate the helpful staff, clean rooms, and convenient access to High Springs Civic Center Park and Museum.
"Great place to stay."
United States
Wesley
The price is AED 384
AED 432 total
includes taxes & fees
6 Jan - 7 January 2026
BlueGem Motel
Exterior
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
2.0 star property
High Springs
10.0 out of 10, Exceptional, (156)
Immerse yourself in natural beauty at this High Springs cabin. Each unit offers a kitchenette and private patio. Ruth B. Kirby Gilchrist Blue Springs State Park and Poe Springs Park are just moments away, with free parking on-site.
"Fantastic place! Very nice amenities and service was wonderful"
United States
Annette
The price is AED 364
AED 723 total
includes taxes & fees
5 Jan - 6 January 2026
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
Breakfast area
Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75
2.5 star property
Alachua
9.4 out of 10, Exceptional, (473)
Located in Alachua, this welcoming hotel offers an outdoor pool and fitness center just minutes from the Sports Complex. Clean rooms and helpful staff create a relaxing atmosphere, while free parking adds convenience for business and leisure travelers alike.
"Staff very helpful- clean updated facility. "
United States
bethany
The price is AED 373
AED 420 total
includes taxes & fees
5 Jan - 6 January 2026
Hampton Inn & Suites Alachua I-75
Desk, blackout drapes, iron/ironing board, rollaway beds
Americas Best Value Inn Alachua

Americas Best Value Inn Alachua

Americas Best Value Inn Alachua
2.0 star property
Alachua
4.8 out of 10, (599)
Located near Alachua Sports Complex, this budget-friendly motel offers an inviting outdoor pool for cooling off. Enjoy free WiFi and parking, with comfortable accommodations just minutes from community attractions.
"Staff was helpful and so courteous.."
United States
Christian
The price is AED 222
AED 249 total
includes taxes & fees
25 Dec - 26 Dec
Americas Best Value Inn Alachua
BBQ/picnic area
Cindys Motel

Cindys Motel

Cindys Motel
2.5 star property
Mayo
8.8 out of 10, Excellent, (128)
Located near Veteran's Memorial Park of Mayo and Lafayette County Library, this motel offers free WiFi and parking. Guests consistently praise the attentive staff and daily housekeeping that ensure a pleasant stay.
"Nice place"
Australia
Marie
Cindys Motel
3 outdoor pools, open 10:00 AM to 10:00 PM, sun loungers
Suwannee River Rendezvous

Suwannee River Rendezvous

Suwannee River Rendezvous
2.5 star property
Mayo
8.6 out of 10, Excellent, (19)
Nestled in Mayo, this resort offers a scenic escape with 3 outdoor pools and The Cookin' Shack restaurant serving three daily meals. Explore nearby Peacock Springs State Park while enjoying free WiFi and parking.
"Always a good time!"
United States
Madalaine
The price is AED 90
AED 149 total
includes taxes & fees
27 Dec - 28 Dec
Suwannee River Rendezvous
Suite, Multiple Beds, Accessible, Non Smoking | Pillowtop beds, desk, laptop workspace, iron/ironing board
Comfort Suites Lake City

Comfort Suites Lake City

Comfort Suites Lake City
2.5 star property
Lake City
9.6 out of 10, Exceptional, (1000)
Enjoy the outdoor pool and free breakfast at this welcoming Lake City hotel. Located close to Regal UA Cinema 90 and Lake City Mall, guests appreciate the helpful staff, fitness center, and convenient free parking and WiFi.
"Great staff"
United States
Alison
The price is AED 393
AED 442 total
includes taxes & fees
11 Jan - 12 January 2026
Comfort Suites Lake City
Lobby
Hampton Inn & Suites Lake City

Hampton Inn & Suites Lake City

Hampton Inn & Suites Lake City
2.5 star property
Lake City
9.4 out of 10, Exceptional, (1001)
Soak up Florida sunshine at the outdoor pool of this welcoming hotel. Located near Regal UA Cinema 90 and Lake City Mall, it offers free breakfast, WiFi, and parking. Clean rooms and helpful staff ensure a pleasant business or leisure stay.
"Clean room, staff, everyone super helpful ."
United States
Devang
The price is AED 426
AED 479 total
includes taxes & fees
11 Jan - 12 January 2026
Hampton Inn & Suites Lake City
Exterior
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
3.5 star property
Alachua
9.4 out of 10, Exceptional, (1000)
Experience comfort at this Alachua hotel featuring an outdoor pool and hot tub. Enjoy complimentary breakfast, WiFi, and parking while staying close to Alachua Sports Complex. Business-friendly accommodations include in-room refrigerators and microwaves, with a 24-hour fitness center for active travelers.
"Easy check in, friendly staff, hot tub, nice clean rooms. "
United States
Kelsey
The price is AED 415
AED 467 total
includes taxes & fees
28 Dec - 29 Dec
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
Exterior
Holiday Inn & Suites Lake City by IHG

Holiday Inn & Suites Lake City by IHG

Holiday Inn & Suites Lake City by IHG
3.0 star property
Lake City
8.6 out of 10, Excellent, (1000)
Enjoy a refreshing swim in the indoor pool before grabbing a bite at The Atrium restaurant. This hotel offers free WiFi, parking, and a 24-hour fitness center, all minutes from Regal UA Cinema 90 and Lake City Mall. Staff receives high marks from guests.
"Nice hotel but a little pricey "
United States
Hilary
The price is AED 364
AED 409 total
includes taxes & fees
18 Jan - 19 January 2026
Holiday Inn & Suites Lake City by IHG
Terrace/patio
Home2 Suites by Hilton Lake City

Home2 Suites by Hilton Lake City

Home2 Suites by Hilton Lake City
3.0 star property
Lake City
9.4 out of 10, Exceptional, (734)
Enjoy a peaceful stay at this clean, quiet hotel featuring an outdoor pool, 24-hour fitness center, and complimentary breakfast. Located near Regal UA Cinema 90 and Lake City Mall, with free parking and helpful staff to enhance your visit.
"Th room was spotless and well laid out. Reagan was so friendly and helpful when we checked in at 1am. "
United States
Heather
The price is AED 449
AED 506 total
includes taxes & fees
4 Jan - 5 January 2026
Home2 Suites by Hilton Lake City
Lobby
Fairfield Inn & Suites Lake City

Fairfield Inn & Suites Lake City

Fairfield Inn & Suites Lake City
2.5 star property
Lake City
9.0 out of 10, Wonderful, (167)
Unwind at this welcoming Lake City retreat where the indoor pool refreshes morning swimmers and the hot tub soothes evening relaxers. Free breakfast, WiFi and parking enhance your stay near Regal UA Cinema 90 and Lake City Mall.
"Very clean, friendly staff, safe and quiet "
United States
Amy
The price is AED 327
AED 368 total
includes taxes & fees
11 Jan - 12 January 2026
Fairfield Inn & Suites Lake City
Lobby
Best Western Plus Lake City

Best Western Plus Lake City

Best Western Plus Lake City
2.5 star property
Lake City
9.2 out of 10, Wonderful, (1021)
Enjoy a refreshing dip in the indoor pool after a day of exploration. This hotel offers complimentary breakfast, WiFi and parking. Located near Regal UA Cinema 90 and Lake City Mall, with attentive staff ready to enhance your stay.
"Fantastic stay 10/10"
United States
Michael
The price is AED 321
AED 361 total
includes taxes & fees
28 Dec - 29 Dec
Best Western Plus Lake City
Exterior
La Quinta Inn & Suite by Wyndham Lake City

La Quinta Inn & Suite by Wyndham Lake City

La Quinta Inn & Suite by Wyndham Lake City
2.5 star property
Lake City
8.8 out of 10, Excellent, (1019)
Experience comfort at this hotel with a 24-hour fitness center and indoor pool. Near Regal UA Cinema 90 and Lake City Mall, guests praise the free breakfast and helpful staff. Enjoy free WiFi and parking during your stay.
"Very clean property and a full hot breakfast buffet! "
United States
Julie
The price is AED 344
AED 387 total
includes taxes & fees
25 Dec - 26 Dec
La Quinta Inn & Suite by Wyndham Lake City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about O Brien

Escape to this rural Florida gem where the Suwannee River offers peaceful kayaking trips and fishing adventures. Nearby Spirit of the Suwannee Music Park hosts live concerts, while O'Brien's local farms welcome visitors for fresh produce and family-friendly activities.

See all hotels in O Brien
kayakers at Rock Bluff Spring on the Suwanneee River, Gilchrist County, Florida

Top O Brien Hotel Reviews

Fairfield Inn & Suites Lake City

Fairfield Inn & Suites Lake City

10/10 Excellent
"Yes"
Trinece 1-night trip
Posted 2 days ago
Fairfield Inn & Suites Lake City

More cheap stays in O Brien

Motel 6 – Lake City, Fl – Medical Center

Motel 6 – Lake City, Fl – Medical Center

3340 W US Highway 90 Lake City FL
The price is AED 225 per night from Dec 28 to Dec 29
AED 225
AED 253 total
28 Dec - 29 Dec
includes taxes & fees
8.2/10 Very Good! (77 reviews)

Hotels in O Brien with star-rating

Frequently asked questions

Where is the best place to stay in O Brien?
La Quinta Inn & Suite by Wyndham Lake City, located 18.2 mi (29.3 km) from the heart of O Brien, is a top choice for your stay based on our traveler data. Other good choices for your visit to the area are Holiday Inn Express & Suites Alachua - Gainesville Area by IHG and Tru by Hilton Lake City. See all available top hotels, or vacation rentals in O Brien.
What's the top vacation rental in O Brien?
Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!: Visitors like this O Brien vacation home rental. It is located on the beach and has a balcony, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a selection of games. See all vacation rentals in O Brien.
If I need to cancel my hotel reservation in O Brien, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in O Brien.
Where can I learn more about changing or cancelling my trip to O Brien?
To access more information about picking new dates or cancelling your trip to O Brien, click here.
Where is the best hotel to stay near Ichetucknee Springs State Park?
Escape to Nature - 2 miles from Ichetucknee park is one of the top choices for your stay based on our traveler data, and this property features in-room kitchens and fireplaces. It's located 2.3 mi (3.8 km) from Ichetucknee Springs State Park. Another good choice is A Riverview of a Magical Sunrise every morning, located 5.6 mi (9.1 km) away.
What are some accommodations with pools in O Brien?
La Quinta Inn & Suite by Wyndham Lake City: Offers on-the-go, an indoor pool, and free self parking. Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks! and Holiday Inn Express & Suites Alachua - Gainesville Area by IHG are two additional hotels that feature an onsite pool. View all hotels with pools in O Brien.
What's the best hotel for staying near Gainesville Regional Airport (GNV)?
Hampton Inn & Suites Gainesville Downtown is one of the top choices for your stay and is a popular hotel, featuring free breakfast and an outdoor pool. It's located 3.7 mi (6 km) from Gainesville Regional Airport. Other good choices close to the airport include Sweetwater Branch Inn and Travelers Inn.
How is it to stay in O Brien?
Visitors to O Brien are sure to find plenty to explore and enjoy. In O Brien, there are 11 hotels and other accommodations to choose from. Find out more about O Brien.
What should I see while I'm in O Brien?
Natural beauty is on display at Suwannee River, Ichetucknee River, and Ichetucknee Springs State Park. You'll also find Troy Spring State Park and Bob's River Place in the area. Check out what more to see and do in Expedia's O Brien guide.
What's the seasonal weather like in O Brien?
The hottest months are usually July and August with an average temp of 80°F, while the coldest months are January and February with an average of 58°F. Average annual precipitation for O Brien is 50 inches.

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