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Find hotels in O Brien, FL from AED 204

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Compare 337 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
3.5 star property
9.4 out of 10, Exceptional, (1004)
"Clean rooms, helpful staff, great breakfast"
United States
Bambi
The price is AED 448
AED 504 total
includes taxes & fees
5 Nov - 6 Nov
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
La Quinta Inn & Suite by Wyndham Lake City
2.5 star property
8.8 out of 10, Excellent, (1006)
"Parking was good- easy and accessible. The room was clean and nice. We loved the bathroom- large and clean. We would stay here again in a heartbeat!"
United States
Ruth
The price is AED 354
AED 398 total
includes taxes & fees
16 Nov - 17 Nov
La Quinta Inn & Suite by Wyndham Lake City
Americas Best Value Inn Alachua
2.0 star property
4.8 out of 10, (592)
"Staff very helpful and property clean"
United States
Donna
The price is AED 247
AED 277 total
includes taxes & fees
3 Nov - 4 Nov
Americas Best Value Inn Alachua
Hampton Inn & Suites Alachua I-75
2.5 star property
9.4 out of 10, Exceptional, (464)
"We would definitely stay here again if we are ever in this area. "
United States
KAREN
The price is AED 413
AED 464 total
includes taxes & fees
30 Nov - 1 Dec
Hampton Inn & Suites Alachua I-75
Best Western Plus Lake City
2.5 star property
9.2 out of 10, Wonderful, (1045)
"Staff were friendly and helpful. Located right off I75 which was very convenient. Breakfast was good and area clean."
United States
Mary
The price is AED 305
AED 343 total
includes taxes & fees
9 Nov - 10 Nov
Best Western Plus Lake City
Courtyard By Marriott Lake City
3.0 star property
9.6 out of 10, Exceptional, (164)
"Nice place for a weekend trip to the springs close by.Would definitely stay here again."
United States
Mary
The price is AED 393
AED 442 total
includes taxes & fees
16 Nov - 17 Nov
Courtyard By Marriott Lake City
Comfort Suites Lake City
2.5 star property
9.6 out of 10, Exceptional, (1005)
"Amazing place to stay"
United States
Felix
The price is AED 340
AED 383 total
includes taxes & fees
10 Nov - 11 Nov
Comfort Suites Lake City
Postcard Cabins Gilchrest Spring, Outdoor Collection by Marriott Bonvoy
2.0 star property
10.0 out of 10, Exceptional, (131)
"Great place to getaway. "
United States
Carlyson Barros
The price is AED 474
AED 683 total
includes taxes & fees
3 Nov - 4 Nov
Postcard Cabins Gilchrest Spring, Outdoor Collection by Marriott Bonvoy
High Springs Country Inn
2.0 star property
8.6 out of 10, Excellent, (12)
"It was a comfortable stay for one night"
United States
Thomas
The price is AED 270
AED 304 total
includes taxes & fees
16 Nov - 17 Nov
High Springs Country Inn
Baymont by Wyndham Lake City I-75
2.5 star property
5.0 out of 10, (1002)
"Easy check-in and friendly front desk staff. The room was very clean and the bed was comfy!"
United States
Maura
The price is AED 212
AED 239 total
includes taxes & fees
3 Nov - 4 Nov
Baymont by Wyndham Lake City I-75
Quality Inn White Springs Suwanee
2.5 star property
7.2 out of 10, Good, (596)
"Clean, Location"
United States
Jeffrey
The price is AED 240
AED 264 total
includes taxes & fees
3 Nov - 4 Nov
Quality Inn White Springs Suwanee
Tru by Hilton Lake City
2.5 star property
9.2 out of 10, Wonderful, (1014)
"Good hotel"
United States
Frank
The price is AED 400
AED 450 total
includes taxes & fees
9 Nov - 10 Nov
Tru by Hilton Lake City
Days Inn by Wyndham Lake City I-10
2.0 star property
6.8 out of 10, (1002)
"It s a very nice hotel"
United States
Denise
The price is AED 220
AED 248 total
includes taxes & fees
3 Nov - 4 Nov
Days Inn by Wyndham Lake City I-10
Quality Inn Lake City
2.5 star property
7.8 out of 10, Good, (942)
"Everything was great about this property and the staff were very friendly and accommodating. "
United States
Andrew
The price is AED 247
AED 277 total
includes taxes & fees
2 Dec - 3 Dec
Quality Inn Lake City
Americas Best Value Inn Lake City
2.0 star property
8.8 out of 10, Excellent, (1003)
"Reasonably priced, nice and clean, easy access to I 75"
United States
Dianne
The price is AED 261
AED 294 total
includes taxes & fees
3 Nov - 4 Nov
Americas Best Value Inn Lake City
Fairfield Inn & Suites Lake City
2.5 star property
9.0 out of 10, Wonderful, (139)
"Awesome stay the staff is very friendly."
United States
Susan
The price is AED 360
AED 405 total
includes taxes & fees
9 Nov - 10 Nov
Fairfield Inn & Suites Lake City
BlueGem Motel
2.0 star property
9.2 out of 10, Wonderful, (380)
"Great hotel"
United States
Wesley
The price is AED 343
AED 386 total
includes taxes & fees
23 Nov - 24 Nov
BlueGem Motel
Hampton Inn & Suites Lake City
2.5 star property
9.4 out of 10, Exceptional, (1001)
"It was a great stay "
United States
Miranda
The price is AED 387
AED 435 total
includes taxes & fees
16 Nov - 17 Nov
Hampton Inn & Suites Lake City
Days Inn by Wyndham Lake City I-75
2.0 star property
7.4 out of 10, Good, (1001)
"Very clean! Very friendly staff! "
United States
Marleis
The price is AED 253
AED 285 total
includes taxes & fees
1 Dec - 2 Dec
Days Inn by Wyndham Lake City I-75
Motel 6 – Lake City, Fl – Medical Center
2.0 star property
8.4 out of 10, Very Good, (24)
"Clean and spacious room, helpful staff."
United States
Rebecca
The price is AED 182
AED 204 total
includes taxes & fees
6 Nov - 7 Nov
Motel 6 – Lake City, Fl – Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about O Brien

Escape to this rural Florida gem where the Suwannee River offers peaceful kayaking trips and fishing adventures. Nearby Spirit of the Suwannee Music Park hosts live concerts, while O'Brien's local farms welcome visitors for fresh produce and family-friendly activities.

An amazing state Park 2 hours drive from Orlando. Swimming and snorkeling in this crystal clear water is allowed and i really recommend to do it! 🐟🐢
Photo by Dr__Vlad
Open Photo by Dr__Vlad

Top O Brien Hotel Reviews

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Hotels in O Brien with star-rating

Frequently asked questions

Where is the best place to stay in O Brien?
Best Western Plus Lake City, located 17.9 mi (28.8 km) from the heart of O Brien, is a top choice for your stay based on our traveler data. Other good choices for your visit to the area are La Quinta Inn & Suite by Wyndham Lake City and Holiday Inn Express & Suites Alachua - Gainesville Area by IHG. See all available top hotels, or vacation rentals in O Brien.
What's the top vacation rental in O Brien?
Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!: Visitors like this O Brien vacation home rental. It is located on the beach and has a balcony, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a selection of games. See all vacation rentals in O Brien.
If I need to cancel my hotel reservation in O Brien, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in O Brien.
Where can I learn more about changing or cancelling my trip to O Brien?
To access more information about picking new dates or cancelling your trip to O Brien, click here.
Where is the best hotel to stay near Ichetucknee Springs State Park?
Escape to Nature - 2 miles from Ichetucknee park is one of the top choices for your stay based on our traveler data, and this property features in-room kitchens and fireplaces. It's located 2.3 mi (3.8 km) from Ichetucknee Springs State Park. Another good choice is A Riverview of a Magical Sunrise every morning, located 5.6 mi (9.1 km) away.
What are some accommodations with pools in O Brien?
Best Western Plus Lake City: Features a snack bar/deli, an indoor pool, and buffet. La Quinta Inn & Suite by Wyndham Lake City and Holiday Inn Express & Suites Alachua - Gainesville Area by IHG are two additional hotels that feature an onsite pool. View all hotels with pools in O Brien.
What's the best hotel for staying near Gainesville Regional Airport (GNV)?
Hampton Inn & Suites Gainesville Downtown is one of the top choices for your stay and is a popular hotel, featuring free breakfast and an outdoor pool. It's located 3.7 mi (6 km) from Gainesville Regional Airport. Other good choices close to the airport include Sweetwater Branch Inn and Travelers Inn.
How is it to stay in O Brien?
Visitors to O Brien are sure to find plenty to explore and enjoy. In O Brien, there are 10 hotels and other accommodations to choose from. Find out more about O Brien.
What should I see while I'm in O Brien?
Natural beauty is on display at Suwannee River, Ichetucknee River, and Ichetucknee Springs State Park. You'll also find Wes Skiles Peacock Springs State Park and Lafayette Blue Springs State Park in the area. Check out what more to see and do in Expedia's O Brien guide.
What's the seasonal weather like in O Brien?
The hottest months are usually July and August with an average temp of 80°F, while the coldest months are January and February with an average of 58°F. Average annual precipitation for O Brien is 50 inches.

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