Find hotels in O Brien, FL from AED 159

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Check prices for these dates

Tonight
25 Mar - 26 Mar
Tomorrow
26 Mar - 27 Mar
This weekend
27 Mar - 29 Mar
Next weekend
3 Apr - 5 Apr

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Our top choices for O Brien hotels

Down comforters, pillowtop beds, blackout drapes, free WiFi

Super 8 by Wyndham Lake City

Super 8 by Wyndham Lake City
2.0 star property
Lake City
7.2 out of 10, Good, (701 reviews)
"Daniele at the front was amazing . Loved her , she made sure our stay was perfect ! Breakfast was yummy too!"
United States
Megan
The price is AED 240
AED 270 total
includes taxes & fees
5 Apr - 6 Apr
Super 8 by Wyndham Lake City
Individually decorated, desk, laptop workspace, iron/ironing board

Days Inn by Wyndham Lake City I-10

Days Inn by Wyndham Lake City I-10
2.0 star property
Lake City
7.0 out of 10, Good, (1,002 reviews)
"Not a place we would stay again. Bed comfortable. Room clean. Not much for Breakfast. Area didn’t really feel safe. "
Canada
Donna Marie
The price is AED 198
AED 223 total
includes taxes & fees
26 Mar - 27 Mar
Days Inn by Wyndham Lake City I-10
Studio, 1 King Bed | Premium bedding, desk, blackout drapes, soundproofing

Palms Garden Inn

Palms Garden Inn
2.0 star property
Lake City
7.4 out of 10, Good, (600 reviews)
"room was clean and the air conditioning worked great would recommend"
United States
david
The price is AED 239
AED 268 total
includes taxes & fees
26 Mar - 27 Mar
Palms Garden Inn
Lobby

Americas Best Value Inn Lake City

Americas Best Value Inn Lake City
2.0 star property
Lake City
8.6 out of 10, Excellent, (1,003 reviews)
"Clean place to stay "
United States
Michelle
The price is AED 247
AED 277 total
includes taxes & fees
29 Mar - 30 Mar
Americas Best Value Inn Lake City
Lobby

Best Western Plus Lake City

Best Western Plus Lake City
2.5 star property
Lake City
9.0 out of 10, Wonderful, (1,031 reviews)
"Clean room, easy check in/out, friendly staff, friendly staff, simple but delicious breakfast. "
United States
Sara
The price is AED 366
AED 412 total
includes taxes & fees
30 Mar - 31 Mar
Best Western Plus Lake City
Breakfast area

Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75
2.5 star property
Alachua
9.4 out of 10, Exceptional, (492 reviews)
"Breakfast awesome Parking great Staff awesome "
United States
Bryan
The price is AED 422
AED 474 total
includes taxes & fees
12 Apr - 13 Apr
Hampton Inn & Suites Alachua I-75
Outdoor dining

Motel 6 – Lake City, Fl – Medical Center

Motel 6 – Lake City, Fl – Medical Center
2.0 star property
Lake City
8.0 out of 10, Very Good, (124 reviews)
"Dog friendly and price."
United States
John
The price is AED 246
AED 277 total
includes taxes & fees
29 Mar - 30 Mar
Motel 6 – Lake City, Fl – Medical Center
Exterior

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
3.5 star property
Alachua
9.4 out of 10, Exceptional, (1,001 reviews)
"Clean hotel and friendly staff"
United States
Joseph
The price is AED 415
AED 467 total
includes taxes & fees
29 Mar - 30 Mar
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
Exterior

La Quinta Inn & Suite by Wyndham Lake City

La Quinta Inn & Suite by Wyndham Lake City
2.5 star property
Lake City
8.8 out of 10, Excellent, (1,087 reviews)
"Excellent place to stay."
United States
Donovan
The price is AED 367
AED 413 total
includes taxes & fees
29 Mar - 30 Mar
La Quinta Inn & Suite by Wyndham Lake City
Indoor pool

Fairfield Inn & Suites Lake City

Fairfield Inn & Suites Lake City
3.0 star property
Lake City
9.0 out of 10, Wonderful, (212 reviews)
"Clean room, friendly staff, most comfortable beds ever and great breakfast!!!"
United States
Kristie
The price is AED 400
AED 450 total
includes taxes & fees
29 Mar - 30 Mar
Fairfield Inn & Suites Lake City
Lobby

Quality Inn White Springs Suwanee

Quality Inn White Springs Suwanee
2.5 star property
Live Oak
7.2 out of 10, Good, (650 reviews)
"Great breakfast! The best staff you can get at a hotel!"
United States
vicki
The price is AED 250
AED 275 total
includes taxes & fees
7 Apr - 8 Apr
Quality Inn White Springs Suwanee
Pillowtop beds, in-room safe, desk, blackout drapes

Days Inn by Wyndham Lake City I-75

Days Inn by Wyndham Lake City I-75
2.0 star property
Lake City
7.6 out of 10, Good, (1,000 reviews)
"Accessable really was accessible "
United States
Sondra
The price is AED 232
AED 261 total
includes taxes & fees
30 Mar - 31 Mar
Days Inn by Wyndham Lake City I-75
Outdoor pool, open 9:00 AM to 10:00 PM, sun loungers

Hampton Inn & Suites Lake City

Hampton Inn & Suites Lake City
2.5 star property
Lake City
9.4 out of 10, Exceptional, (1,000 reviews)
"Nice stay"
United States
Timothy
The price is AED 455
AED 512 total
includes taxes & fees
5 Apr - 6 Apr
Hampton Inn & Suites Lake City
Terrace/patio

Home2 Suites by Hilton Lake City

Home2 Suites by Hilton Lake City
3.0 star property
Lake City
9.4 out of 10, Exceptional, (774 reviews)
"Very clean property, staff was always helpful and kind. "
United States
Tosha
The price is AED 477
AED 536 total
includes taxes & fees
5 Apr - 6 Apr
Home2 Suites by Hilton Lake City
Pillowtop beds, desk, iron/ironing board, free WiFi

Quality Inn Lake City

Quality Inn Lake City
2.5 star property
Lake City
8.0 out of 10, Very Good, (1,001 reviews)
"Great hotel and staff"
United States
Cynthia
The price is AED 297
AED 334 total
includes taxes & fees
1 Apr - 2 Apr
Quality Inn Lake City
Lobby

Regal Inn

Regal Inn
2.5 star property
Lake City
8.6 out of 10, Excellent, (574 reviews)
"Nice staff, the room was clean and the bed was comfortable. "
United States
Karen
The price is AED 228
AED 256 total
includes taxes & fees
29 Mar - 30 Mar
Regal Inn
Suite, Multiple Beds, Accessible, Non Smoking | Pillowtop beds, desk, laptop workspace, iron/ironing board

Comfort Suites Lake City

Comfort Suites Lake City
2.5 star property
Lake City
9.6 out of 10, Exceptional, (1,000 reviews)
"Clean room and facilities with very friendly staff during our entire stay."
United States
Moriah
The price is AED 412
AED 463 total
includes taxes & fees
15 Apr - 16 Apr
Comfort Suites Lake City
Exterior

Holiday Inn & Suites Lake City by IHG

Holiday Inn & Suites Lake City by IHG
3.0 star property
Lake City
8.6 out of 10, Excellent, (1,001 reviews)
"Quick service and clean rooms"
United States
Lexus
The price is AED 349
AED 393 total
includes taxes & fees
29 Mar - 30 Mar
Holiday Inn & Suites Lake City by IHG
Free daily on-the-go breakfast

Tru by Hilton Lake City

Tru by Hilton Lake City
2.5 star property
Lake City
9.2 out of 10, Wonderful, (1,005 reviews)
"Staff was very welcoming and pleasant! Great facility and location for access to multiple eating options. "
United States
Russ
The price is AED 400
AED 450 total
includes taxes & fees
29 Mar - 30 Mar
Tru by Hilton Lake City
Reception

The Blanche

The Blanche
2.0 star property
Lake City
9.2 out of 10, Wonderful, (177 reviews)
"Loved the hotel and the location! The bed was very very soft and the microfiber sheets were thin and hot!"
United States
Kim
The Blanche
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about O Brien

Escape to this rural Florida gem where the Suwannee River offers peaceful kayaking trips and fishing adventures. Nearby Spirit of the Suwannee Music Park hosts live concerts, while O'Brien's local farms welcome visitors for fresh produce and family-friendly activities.

See all hotels in O Brien
kayakers at Rock Bluff Spring on the Suwanneee River, Gilchrist County, Florida

Top O Brien Hotel Reviews

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

10/10 Excellent
"Heated pool and hot tub! Major plus and the breakfast was also awesome! Staff was very helpful and took great care of my family."
Leah 1-night trip
Posted 5 hours ago
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

More cheap stays in O Brien

Americas Best Value Inn Lake City

Americas Best Value Inn Lake City

3835 West US Highway 90 Lake City FL
The price is AED 247 per night from Mar 29 to Mar 30
AED 247
AED 277 total
29 Mar - 30 Mar
includes taxes & fees
8.6/10 Excellent! (1,003 reviews)

Frequently asked questions

Where is the best place to stay in O Brien?
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG, located 29.9 mi (48.2 km) from the heart of O Brien, is a top choice for your stay based on our traveler data. Other good choices for your visit to the area are La Quinta Inn & Suite by Wyndham Lake City and Best Western Plus Lake City. See all available top hotels, or vacation rentals in O Brien.
What's the top vacation rental in O Brien?
Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!: Visitors like this O Brien vacation home rental. It is located on the beach and has a balcony, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a selection of games. See all vacation rentals in O Brien.
If I need to cancel my hotel reservation in O Brien, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in O Brien.
Where can I learn more about changing or cancelling my trip to O Brien?
To access more information about picking new dates or cancelling your trip to O Brien, click here.
Where is the best hotel to stay near Ichetucknee Springs State Park?
Escape to Nature - 2 miles from Ichetucknee park is one of the top choices for your stay based on our traveler data, and this property features in-room kitchens and fireplaces. It's located 2.3 mi (3.8 km) from Ichetucknee Springs State Park. Another good choice is A Riverview of a Magical Sunrise every morning, located 5.6 mi (9.1 km) away.
What are some accommodations with pools in O Brien?
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG: Offers buffet, an outdoor pool, and complimentary wired internet access. Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks! and La Quinta Inn & Suite by Wyndham Lake City are two additional hotels that feature an onsite pool. View all hotels with pools in O Brien.
What's the best hotel for staying near Gainesville Regional Airport (GNV)?
Hampton Inn & Suites Gainesville Downtown is one of the top choices for your stay and is a popular hotel, featuring free breakfast and an outdoor pool. It's located 3.7 mi (6 km) from Gainesville Regional Airport. Other good choices close to the airport include Sweetwater Branch Inn and Travelers Inn.
How is it to stay in O Brien?
Visitors to O Brien are sure to find plenty to explore and enjoy. In O Brien, there are 11 hotels and other accommodations to choose from. Find out more about O Brien.
What should I see while I'm in O Brien?
Natural beauty is on display at Suwannee River, Ichetucknee River, and Ichetucknee Springs State Park. You'll also find Wes Skiles Peacock Springs State Park and Lake City Mall in the area. Check out what more to see and do in Expedia's O Brien guide.
What's the seasonal weather like in O Brien?
The hottest months are usually July and August with an average temp of 80°F, while the coldest months are January and February with an average of 58°F. Average annual precipitation for O Brien is 50 inches.