Find hotels near Oklahoma Frontier Drugstore Museum, Guthrie from AEDĀ 177

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
13 Nov - 14 Nov
Tomorrow
14 Nov - 15 Nov
This weekend
13 Nov - 15 Nov
Next weekend
20 Nov - 22 Nov

Filter by

Property class

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Oklahoma Frontier Drugstore Museum hotels

A garden with transparent geodesic domes, string lights, and Christmas trees.

1. Dominion Gardens and Hotel

Dominion Gardens and Hotel
2.5 star property
1.1 km from Oklahoma Frontier Drugstore Museum
9.6 out of 10, Exceptional, (607 reviews)
"Great place to stay, loved it!!"
United States
Terri
The price is AEDĀ 426
AEDĀ 495 total
includes taxes & fees
15 Nov - 16 Nov
Dominion Gardens and Hotel
A two-story building with a central entrance flanked by columns, a covered porch, and a symmetrical facade.

2. The Judge's Chambers

The Judge's Chambers
3.0 star property
1.4 km from Oklahoma Frontier Drugstore Museum
10.0 out of 10, Exceptional, (13 reviews)
"The Rose cottage was very cozy and beautiful. The bed was very comfy."
United States
Coby
The price is AEDĀ 578
AEDĀ 671 total
includes taxes & fees
16 Nov - 17 Nov
The Judge's Chambers
A Holiday Inn Express hotel with a prominent sign, a covered entrance, and a brick facade.

3. Holiday Inn Express & Suites Guthrie North Edmond by IHG

Holiday Inn Express & Suites Guthrie North Edmond by IHG
2.5 star property
2.6 km from Oklahoma Frontier Drugstore Museum
8.4 out of 10, Very good, (1,000 reviews)
"The rooms were clean and the breakfast was very good!"
United States
Francisco
The price is AEDĀ 334
AEDĀ 388 total
includes taxes & fees
13 Dec - 14 Dec
Holiday Inn Express & Suites Guthrie North Edmond by IHG
A hotel with a modern facade, multiple floors, and a well-maintained lawn.

4. Hampton Inn & Suites Guthrie

Hampton Inn & Suites Guthrie
2.5 star property
2.9 km from Oklahoma Frontier Drugstore Museum
8.4 out of 10, Very good, (1,000 reviews)
"Great staff"
United States
Russ
The price is AEDĀ 356
AEDĀ 413 total
includes taxes & fees
6 Dec - 7 Dec
Hampton Inn & Suites Guthrie
A covered outdoor seating area with a wooden pergola, a bench, and a small garden with rocks and plants.

5. Sleep Inn & Suites Guthrie - Edmond North

Sleep Inn & Suites Guthrie - Edmond North
2.5 star property
2.9 km from Oklahoma Frontier Drugstore Museum
8.2 out of 10, Very good, (198 reviews)
"Friendly staff, everything was clean, and it was a very peaceful stay."
United States
Dominic
The price is AEDĀ 265
AEDĀ 308 total
includes taxes & fees
6 Dec - 7 Dec
Sleep Inn & Suites Guthrie - Edmond North
A hotel with a covered entrance, a sign reading "La Quinta Inn & Suites," and a brick facade.

6. La Quinta Inn & Suites by Wyndham Guthrie

La Quinta Inn & Suites by Wyndham Guthrie
3.0 star property
2.9 km from Oklahoma Frontier Drugstore Museum
8.2 out of 10, Very good, (1,001 reviews)
"Breakfast was just ok, but we came in on a Monday and left on Wednesday,"
United States
Daryl
The price is AEDĀ 290
AEDĀ 337 total
includes taxes & fees
15 Nov - 16 Nov
La Quinta Inn & Suites by Wyndham Guthrie
A lobby with a large mural, two black leather sofas, and a chandelier.

7. Quality Inn Guthrie

Quality Inn Guthrie
2.5 star property
2.9 km from Oklahoma Frontier Drugstore Museum
8.2 out of 10, Very good, (901 reviews)
"It was a good one night stay, clean and very comfortable beds!"
United States
Claudia
The price is AEDĀ 177
AEDĀ 205 total
includes taxes & fees
21 Nov - 22 Nov
Quality Inn Guthrie
A hotel room with a bed, a desk with a chair, a television, a mirror, and a microwave.

8. Interstate Motel Guthrie

Interstate Motel Guthrie
2.0 star property
2.4 km from Oklahoma Frontier Drugstore Museum
6.0 out of 10, (139 reviews)
"Staff was wonderful!"
United States
Mary
The price is AEDĀ 257
AEDĀ 298 total
includes taxes & fees
17 Nov - 18 Nov
Interstate Motel Guthrie
A wooden porch with a rocking chair, a potted plant, and a view of a residential area.

9. Legacy Run: Guthries Historic Haven Near Shops

Legacy Run: Guthries Historic Haven Near Shops
3.0 star property
1.6 km from Oklahoma Frontier Drugstore Museum
10.0 out of 10, Exceptional, (1 review)
"We loved it and are definitely rebooking for next year!! very cozy very comfortable!!"
United States
AMANDA
The price is AEDĀ 507
AEDĀ 1,239 total
includes taxes & fees
21 Nov - 22 Nov
Legacy Run: Guthries Historic Haven Near Shops
A kitchen with green cabinets, a coffee machine, and a window with blinds.

10. Guthrie Home in the Heart of Historic Downtown!

Guthrie Home in the Heart of Historic Downtown!
3.0 star property
0.5 km from Oklahoma Frontier Drugstore Museum
The price is AEDĀ 507
AEDĀ 1,370 total
includes taxes & fees
16 Nov - 17 Nov
Guthrie Home in the Heart of Historic Downtown!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare top hotels near Oklahoma Frontier Drugstore Museum

A garden with transparent geodesic domes, string lights, and Christmas trees.

Dominion Gardens and Hotel

2.5 star property
1.1 km from Oklahoma Frontier Drugstore Museum
View
A two-story building with a central entrance flanked by columns, a covered porch, and a symmetrical facade.

The Judge's Chambers

3.0 star property
1.4 km from Oklahoma Frontier Drugstore Museum
View
A Holiday Inn Express hotel with a prominent sign, a covered entrance, and a brick facade.

Holiday Inn Express & Suites Guthrie North Edmond by IHG

2.5 star property
2.6 km from Oklahoma Frontier Drugstore Museum
View
A hotel with a modern facade, multiple floors, and a well-maintained lawn.

Hampton Inn & Suites Guthrie

2.5 star property
2.9 km from Oklahoma Frontier Drugstore Museum
View
A covered outdoor seating area with a wooden pergola, a bench, and a small garden with rocks and plants.

Sleep Inn & Suites Guthrie - Edmond North

2.5 star property
2.9 km from Oklahoma Frontier Drugstore Museum
View
9.6
Exceptional
607 reviews
10.0
Exceptional
13 reviews
8.4
Very good
1,000 reviews
8.4
Very good
1,000 reviews
8.2
Very good
198 reviews
The price is AEDĀ 426
AEDĀ 495 total
includes taxes & fees
15 Nov - 16 Nov
The price is AEDĀ 578
AEDĀ 671 total
includes taxes & fees
16 Nov - 17 Nov
The price is AEDĀ 334
AEDĀ 388 total
includes taxes & fees
13 Dec - 14 Dec
The price is AEDĀ 356
AEDĀ 413 total
includes taxes & fees
6 Dec - 7 Dec
The price is AEDĀ 265
AEDĀ 308 total
includes taxes & fees
6 Dec - 7 Dec
  • Yes, Breakfast included
  • No Pool
  • No Spa
  • No Pet friendly
  • Yes, WiFi included
  • Yes, Parking
  • No Breakfast included
  • No Pool
  • No Spa
  • No Pet friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet friendly
  • No WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • No Pet friendly
  • Yes, WiFi included
  • Yes, Parking

Other attractions near Oklahoma Frontier Drugstore Museum

Guthrie City Hall

Guthrie City Hall is just one of the places to see in Guthrie, so why not enjoy the other things to explore during your travels? Discover the area's festivals and temples.
See properties

Top Oklahoma Frontier Drugstore Museum Hotel Reviews

A two-story building with a central entrance flanked by columns, a covered porch, and a symmetrical facade.
The Judge's Chambers

The Judge's Chambers

The Judge's Chambers
Guthrie

10/10 Excellent

The Rose Cottage was so spacious and quiet and Robin was very friendly and accommodating with requests. She helped with dinner recommendations and shops around town. I would love to come back here again!
United States
Melissa
Reviewed May 12, 2026
The Judge's Chambers

Frequently Asked Questions

What's the area like around Oklahoma Frontier Drugstore Museum?

Oklahoma Frontier Drugstore Museum is located in Guthrie. If you're looking for a convenient place to stay, check out the 32 hotels and other accommodations you'll find within a mile.

What's the best hotel to stay near Oklahoma Frontier Drugstore Museum?

Hilton Garden Inn Edmond / Oklahoma City North, OK is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and free parking. You'll find it 13.5 mi (21.7 km) from Oklahoma Frontier Drugstore Museum. Other good options around the area include Executive Inn and La Quinta Inn & Suites by Wyndham Edmond.

How many hotels will I be able to find close to Oklahoma Frontier Drugstore Museum?

Expedia has 32 hotels and other accommodations within a mile from Oklahoma Frontier Drugstore Museum.

If I need to cancel the hotel reservation for my stay near Oklahoma Frontier Drugstore Museum, will I receive a refund?

Yes, most room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a non-refundable reservation, you might be able to still cancel and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then you can use the "fully refundable" filter to get top deals close to Oklahoma Frontier Drugstore Museum.

Where can I learn more about changing or cancelling my trip in the area near Oklahoma Frontier Drugstore Museum?

For more details about updating your stay near Oklahoma Frontier Drugstore Museum or cancelling it, click here.

What can I see and do near Oklahoma Frontier Drugstore Museum?

You'll want to browse the exhibits at Scottish Rite Temple and Oklahoma Territorial Museum and Carnegie Library. Learn about local history at Guthrie Historic District and Guthrie Depot. If you have some time to wander around the area, you might stop by Jelsma Stadium, Guthrie Golf & Country Club, or Cimarron National Golf Club.