A coastal cityscape with high-rise buildings, a marina, and a clear blue sky.

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Check availability on Panama City Resorts & Hotels with Spas

This weekend
30 Oct - 1 Nov
Next weekend
6 Nov - 8 Nov

Our top choices for Panama City hotels with a spa

A covered outdoor seating area with a view of a city skyline and water.

1. Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2,246 reviews)
  • cleanliness
    Unwind with hot stone massages and facials at this hotel spa with pool views and plush treatment rooms.
The price is AED 482
AED 530 total
includes taxes & fees
1 Nov - 2 Nov
Plaza Paitilla Inn Hotel
A modern spa area with a hot tub, seating, and a city view.

2. Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
San Francisco
8.6 out of 10, Excellent, (1,829 reviews)
  • cleanliness
    Immerse in therapeutic bliss with 2 spa rooms, steam, and sauna at this full-service wellness hotel.
The price is AED 487
AED 536 total
includes taxes & fees
31 Oct - 1 Nov
Megapolis Hotel Panamá
A modern building facade with large glass windows and a visible sign for 'AQUA SPA'.

3. Decapolis Hotel Panama City

Decapolis Hotel Panama City
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,734 reviews)
  • cleanliness
    Revive in Panama's premier hotel spa with Turkish hammam, hydrotherapy, and multiple treatment rooms for total rejuvenation.
The price is AED 323
AED 355 total
includes taxes & fees
31 Oct - 1 Nov
Decapolis Hotel Panama City
A room with two beds, a desk, a chair, and a window with a view of greenery.

4. Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
Tocumen Airport
8.6 out of 10, Excellent, (1,820 reviews)
  • cleanliness
    Rejuvenate at this tranquil resort with pampering spa services, a stunning pool with swim-up bar, and lush gardens perfect for unwinding.
The price is AED 398
AED 437 total
includes taxes & fees
29 Oct - 30 Oct
Riande Aeropuerto Hotel & Casino
A modern bathroom with a large bathtub, two sinks, and a glass-enclosed shower area with a city view.

5. JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.2 out of 10, Wonderful, (1,003 reviews)
  • cleanliness
    Immerse in waterfront tranquility with bay views, rejuvenating in-room massages, and four outdoor pools for a complete spa getaway.
The price is AED 1,084
AED 1,193 total
includes taxes & fees
27 Nov - 28 Nov
JW Marriott Panama
A massage therapy session in a dimly lit room with a bedside table, candles, and a potted plant.

6. Hotel San Felipe

Hotel San Felipe
4.0 star property
Casco Viejo
9.4 out of 10, Exceptional, (468 reviews)
  • cleanliness
    Recharge with daily aromatherapy, couples massages, and a garden-view spa at this stylish Panama City retreat.
The price is AED 575
AED 633 total
includes taxes & fees
28 Oct - 29 Oct
Hotel San Felipe
A rooftop pool with sun loungers and a city skyline in the background.

7. Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
4.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,215 reviews)
  • cleanliness
    Immerse in a full-service spa retreat with 4 treatment rooms, sauna, and steam room at this modern bed & breakfast.
The price is AED 324
AED 561 total
includes taxes & fees
29 Oct - 30 Oct
Waymore Hotel Spa & Casino
A reception desk with a logo, a patterned wall, and a potted plant.

8. Hilton Panama

Hilton Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,001 reviews)
  • cleanliness
    Indulge in blissful wellness at this Panama hotel with a full-service spa, casino, and outdoor pool to restore and rejuvenate.
The price is AED 965
AED 1,061 total
includes taxes & fees
20 Nov - 21 Nov
Hilton Panama
A bedroom with a large wooden wardrobe, a bed with a beige blanket, a pillow with a 'H' logo, and a wall mural of a tree.

9. Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
4.0 star property
Casco Viejo
9.2 out of 10, Wonderful, (1,007 reviews)
  • cleanliness
    Discover revitalizing massages and soothing facials at this historic hotel with a rooftop pool and steam room in Panama's vibrant center.
The price is AED 615
AED 677 total
includes taxes & fees
10 Nov - 11 Nov
Central Hotel Panama Casco Viejo
A bathroom with a large mirror, a sink, and a towel with a flower on a tray.

10. Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
5.0 star property
Casco Viejo
9.8 out of 10, Exceptional, (370 reviews)
  • cleanliness
    Soak in this colonial retreat's full-service spa sanctuary with rooftop pool and historic charm, creating a rejuvenating wellness escape.
The price is AED 1,099
AED 1,209 total
includes taxes & fees
1 Nov - 2 Nov
Hotel La Compañía Casco Antiguo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Panama City

Pool
Hot tub

Spa hotels with pools in Panama City

A high-rise building with a modern architectural design, featuring a grid of windows and balconies.
Megapolis Hotel Panamá

Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
San Francisco
8.6 out of 10, Excellent, (1829)
The price is AED 487
AED 536 total
includes taxes & fees
31 Oct - 1 Nov
Megapolis Hotel Panamá
View all properties

Spa hotels with hot tubs in Panama City

A high-rise building with a modern architectural design, featuring a grid of windows and balconies.
Megapolis Hotel Panamá

Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
San Francisco
8.6 out of 10, Excellent, (1829)
The price is AED 487
AED 536 total
includes taxes & fees
31 Oct - 1 Nov
Megapolis Hotel Panamá
View all properties

Spa hotels with free breakfast in Panama City

A high-rise building with a modern architectural design, featuring a grid of windows and balconies.
Megapolis Hotel Panamá

Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
San Francisco
8.6 out of 10, Excellent, (1829)
The price is AED 487
AED 536 total
includes taxes & fees
31 Oct - 1 Nov
Megapolis Hotel Panamá
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Panama City Hotel Reviews

Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

10/10 Excellent
"Muy buen espacio"
ELIUD 4-night trip
Posted 4 hours ago
Las Americas Golden Tower Panama

Frequently asked questions

Looking to vacation at a spa hotel in Panama City?
Forget the stress of everyday life and book yourself a hotel with a spa. Travelers highly recommend Panama City for its array of shops and gourmet restaurants—your day tour starts here. Be sure to enjoy the cafes during your stay. Spa hotels are a great way to break away from your routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Panama City?
Megapolis Hotel Panamá is a top luxury spa hotel featuring 3 bars, a casino, a shopping mall, and a fitness center. Enjoy a facial, body scrub, or detox wrap at the onsite spa. Other popular spa hotels in Panama City include Waymore Hotel Spa & Casino and Decapolis Hotel Panama City.
How many spa hotels are there in Panama City?
Expedia has 21 spa hotels to choose from in Panama City.
What's there to see and do in Panama City?
Enjoy Panama City with a stop at Albrook Shopping Mall, Via Espana, and Iglesia del Carmen. If you have a little extra time during your trip, you might want to check out Uruguay Street and Avenida Balboa.
What is a Panama City spa hotel?
Spa hotels in Panama City have full on-site spas which offer services like massages and a range of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are great for rest, rejuvenation, and relaxation.