A coastal cityscape with high-rise buildings, a marina, and a clear blue sky.

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Check availability on Panama City Resorts & Hotels with Spas

This weekend
7 Aug - 9 Aug
Next weekend
14 Aug - 16 Aug

Our top choices for Panama City hotels with a spa

Spa

1. W Panama

W Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,005 reviews)
  • cleanliness
    Revitalize at this luxury hotel with three hot tubs, yoga classes, and rejuvenating massage services in a serene garden setting.
The price is AED 1,025
AED 1,127 total
includes taxes & fees
7 Aug - 8 Aug
W Panama
Couples treatment rooms, body treatments, aromatherapy

2. Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
Casco Viejo
9.8 out of 10, Exceptional, (708 reviews)
  • cleanliness
    Indulge in a waterfront spa retreat with outdoor treatment areas and hot stone massages at this beautifully restored Colonial hotel.
The price is AED 1,388
AED 1,527 total
includes taxes & fees
24 Aug - 25 Aug
Sofitel Legend Casco Viejo, Panama City
Executive Suite, 1 King Bed, Partial Ocean View | Bathroom | Separate tub and shower, designer toiletries, hair dryer, slippers

3. JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,002 reviews)
  • cleanliness
    Immerse in waterfront tranquility with bay views, rejuvenating in-room massages, and four outdoor pools for a complete spa getaway.
The price is AED 996
AED 1,096 total
includes taxes & fees
22 Aug - 23 Aug
JW Marriott Panama
Body treatments, body wraps, body scrubs, facials, 4 treatment rooms

4. Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
4.5 star property
Casco Viejo
9.8 out of 10, Exceptional, (335 reviews)
  • cleanliness
    Soak in this colonial retreat's full-service spa sanctuary with rooftop pool and historic charm, creating a rejuvenating wellness escape.
The price is AED 1,246
AED 1,370 total
includes taxes & fees
20 Aug - 21 Aug
Hotel La Compañía Casco Antiguo
Massage in accommodation

5. Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
4.0 star property
Casco Viejo
9.2 out of 10, Wonderful, (1,010 reviews)
  • cleanliness
    Discover revitalizing massages and soothing facials at this historic hotel with a rooftop pool and steam room in Panama's vibrant center.
The price is AED 606
AED 667 total
includes taxes & fees
2 Sep - 3 Sep
Central Hotel Panama Casco Viejo
Reception

6. Hilton Panama

Hilton Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,003 reviews)
  • cleanliness
    Indulge in blissful wellness at this Panama hotel with a full-service spa, casino, and outdoor pool to restore and rejuvenate.
The price is AED 870
AED 957 total
includes taxes & fees
4 Sep - 5 Sep
Hilton Panama
Couples treatment rooms, sauna, hot tub, steam room, Turkish bath

7. Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
San Francisco
8.4 out of 10, Very Good, (1,630 reviews)
  • cleanliness
    Immerse in therapeutic bliss with 2 spa rooms, steam, and sauna at this full-service wellness hotel.
The price is AED 639
AED 703 total
includes taxes & fees
28 Aug - 29 Aug
Megapolis Hotel Panamá
Outdoor pool

8. Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
4.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,050 reviews)
  • cleanliness
    Immerse in a full-service spa retreat with 4 treatment rooms, sauna, and steam room at this modern bed & breakfast.
The price is AED 386
AED 424 total
includes taxes & fees
1 Sep - 2 Sep
Waymore Hotel Spa & Casino
Terrace/patio

9. Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2,224 reviews)
  • cleanliness
    Unwind with hot stone massages and facials at this hotel spa with pool views and plush treatment rooms.
The price is AED 379
AED 417 total
includes taxes & fees
24 Aug - 25 Aug
Plaza Paitilla Inn Hotel
Lobby lounge

10. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (724 reviews)
  • cleanliness
    Discover tranquility at this luxury spa oasis with 5 treatment rooms and a garden retreat for the ultimate wellness escape.
The price is AED 989
AED 1,088 total
includes taxes & fees
14 Aug - 15 Aug
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Panama City

Pool
Hot tub

Spa hotels with pools in Panama City

Terrace/patio
Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2224)
The price is AED 379
AED 417 total
includes taxes & fees
24 Aug - 25 Aug
Plaza Paitilla Inn Hotel
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Spa hotels with hot tubs in Panama City

Front of property
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
4.0 star property
Casco Viejo
9.2 out of 10, Wonderful, (1010)
The price is AED 606
AED 667 total
includes taxes & fees
2 Sep - 3 Sep
Central Hotel Panama Casco Viejo
View all properties

Spa hotels with free breakfast in Panama City

Terrace/patio
Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2224)
The price is AED 379
AED 417 total
includes taxes & fees
24 Aug - 25 Aug
Plaza Paitilla Inn Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Panama City Hotel Reviews

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

10/10 Excellent
"Vert pretty hotel with a great location. A lot of stores, bars and restaurants around."
LAURA 4-night trip
Posted 12 hours ago
Central Hotel Panama Casco Viejo

Frequently asked questions

Looking to vacation at a spa hotel in Panama City?
Forget the stress of everyday life and book yourself a hotel with a spa. Travelers highly recommend Panama City for its array of shops and gourmet restaurants—your day tour starts here. Be sure to enjoy the cafes during your stay. Spa hotels are a great way to break away from your routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Panama City?
Megapolis Hotel Panamá is a top luxury spa hotel featuring 3 bars, a casino, a shopping mall, and a fitness center. Enjoy a facial, body scrub, or detox wrap at the onsite spa. Other popular spa hotels in Panama City include Waymore Hotel Spa & Casino and W Panama.
How many spa hotels are there in Panama City?
Expedia has 21 spa hotels to choose from in Panama City.
What's there to see and do in Panama City?
Enjoy Panama City with a stop at Albrook Shopping Mall, Via Espana, and Iglesia del Carmen. If you have a little extra time during your trip, you might want to check out Uruguay Street and Avenida Balboa.
What is a Panama City spa hotel?
Spa hotels in Panama City have full on-site spas which offer services like massages and a range of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are great for rest, rejuvenation, and relaxation.