A coastal cityscape with high-rise buildings, a marina, and a clear blue sky.

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Our top choices for Panama City hotels with a spa

1. Casa Bianca

Casa Bianca
2.0 star property
Bella Vista
9.8 out of 10, Exceptional, (8 reviews)
"Good place , nice, clean, "
United States
Jose A
The price is AED 575
AED 636 total
includes taxes & fees
14 Nov - 15 Nov
Casa Bianca

2. Hyatt Regency Panama City

Hyatt Regency Panama City
5.0 star property
Bella Vista
9.6 out of 10, Exceptional, (496 reviews)
"Enjoyed our stay"
United States
Mariah
The price is AED 848
AED 933 total
includes taxes & fees
4 Nov - 5 Nov
Hyatt Regency Panama City

3. The Executive Hotel

The Executive Hotel
3.5 star property
Bella Vista
9.2 out of 10, Wonderful, (1,305 reviews)
"The staff were very helpful and friendly, also it was a nice location to restaurants and some attractions"
United States
Shereka
The price is AED 293
AED 323 total
includes taxes & fees
27 Nov - 28 Nov
The Executive Hotel

4. Hotel Milan

Hotel Milan
3.0 star property
Bella Vista
9.0 out of 10, Wonderful, (600 reviews)
"Hotel is maintained and managed well, close to many restaurants and transportation."
United States
Michael
The price is AED 147
AED 162 total
includes taxes & fees
14 Nov - 15 Nov
Hotel Milan

5. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (6,162 reviews)
"Excellent breakfast buffet.!!!"
United States
Rafael
The price is AED 485
AED 533 total
includes taxes & fees
1 Dec - 2 Dec
Hotel Riu Plaza Panama

6. TRYP by Wyndham Panamá Centro

TRYP by Wyndham Panamá Centro
3.5 star property
Bella Vista
9.0 out of 10, Wonderful, (1,004 reviews)
"Nice easy, central place to stay in Panama City"
Canada
Kanokwan
The price is AED 318
AED 350 total
includes taxes & fees
10 Nov - 11 Nov
TRYP by Wyndham Panamá Centro

7. Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
5.0 star property
Bella Vista
9.2 out of 10, Wonderful, (1,000 reviews)
"was good"
United States
Juliet
The price is AED 777
AED 855 total
includes taxes & fees
13 Nov - 14 Nov
Bristol Panama, a Registry Collection Hotel

8. Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
4.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,221 reviews)
"Breakfast, Cafe, was just perfect location"
United States
Bruno
The price is AED 324
AED 561 total
includes taxes & fees
9 Nov - 10 Nov
Waymore Hotel Spa & Casino

9. Hotel Dann Carlton Marinn Place Panama Financial District

Hotel Dann Carlton Marinn Place Panama Financial District
4.5 star property
Bella Vista
9.0 out of 10, Wonderful, (539 reviews)
"Breakfast was great, and location!!"
United States
Oscar
The price is AED 298
AED 436 total
includes taxes & fees
2 Dec - 3 Dec
Hotel Dann Carlton Marinn Place Panama Financial District

10. La Résidence Panamá

La Résidence Panamá
3.5 star property
Bella Vista
9.2 out of 10, Wonderful, (21 reviews)
"Excellent rooms and fantastic staff!"
United States
Mohamad
The price is AED 503
AED 553 total
includes taxes & fees
3 Nov - 4 Nov
La Résidence Panamá

11. Riande Urban Hotel

Riande Urban Hotel
3.5 star property
Bella Vista
8.8 out of 10, Excellent, (1,039 reviews)
"Good breakfast and staff"
United States
Travis
The price is AED 293
AED 323 total
includes taxes & fees
3 Nov - 4 Nov
Riande Urban Hotel

12. Hilton Panama

Hilton Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,001 reviews)
"Perfect location close to the financial district, local markets, and great restaurants."
United States
Simon
The price is AED 965
AED 1,061 total
includes taxes & fees
20 Nov - 21 Nov
Hilton Panama

13. W Panama

W Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,005 reviews)
"Had an amazing trip, the staff were amazing!!!"
United States
Naomi
The price is AED 949
AED 1,044 total
includes taxes & fees
22 Nov - 23 Nov
W Panama

14. Hotel Mio Panama

Hotel Mio Panama
3.0 star property
Bella Vista
8.8 out of 10, Excellent, (286 reviews)
"Great place and great location"
United States
Nfamory
The price is AED 218
AED 241 total
includes taxes & fees
5 Nov - 6 Nov
Hotel Mio Panama

15. Toscana Inn

Toscana Inn
3.5 star property
Bella Vista
8.8 out of 10, Excellent, (792 reviews)
"Wonderful staff,great hotel,perfect location"
Canada
Dalton
The price is AED 236
AED 260 total
includes taxes & fees
6 Nov - 7 Nov
Toscana Inn

16. Waldorf Astoria Panama

Waldorf Astoria Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,001 reviews)
"The room was very nice, the bar staff and front desk staff were very helpful."
United States
Oscar
The price is AED 1,044
AED 1,149 total
includes taxes & fees
7 Nov - 8 Nov
Waldorf Astoria Panama

17. Hotel Coral Suites

Hotel Coral Suites
3.5 star property
Bella Vista
8.8 out of 10, Excellent, (1,003 reviews)
"Great hotel."
Canada
peter
The price is AED 271
AED 298 total
includes taxes & fees
6 Nov - 7 Nov
Hotel Coral Suites

18. Luxury City View Apartments at Worldwide

Luxury City View Apartments at Worldwide
3.0 star property
Bella Vista
10.0 out of 10, Exceptional, (4 reviews)
"The place is peaceful and its close to restaurants and supermarkets. I would booked dem again in future"
United States
Denesha
The price is AED 267
AED 295 total
includes taxes & fees
25 Nov - 26 Nov
Luxury City View Apartments at Worldwide

19. Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
San Francisco
8.6 out of 10, Excellent, (1,829 reviews)
"Loved our stay there"
United States
Amanda
The price is AED 553
AED 609 total
includes taxes & fees
3 Nov - 4 Nov
Megapolis Hotel Panamá

20. Hilton Garden Inn Panama City Downtown, Panama

Hilton Garden Inn Panama City Downtown, Panama
3.5 star property
Bella Vista
8.8 out of 10, Excellent, (1,001 reviews)
"It was the wonderful stay highly recommended. It keeps it downtown, easy access to where you need to go Uber will pick you right in front well manage! Wonderful service great staff!"
United States
carla
The price is AED 328
AED 361 total
includes taxes & fees
30 Nov - 1 Dec
Hilton Garden Inn Panama City Downtown, Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Choose what matters most at spa hotels in Panama City

Spa hotels with pools in Panama City

Spa hotels with hot tubs in Panama City

Spa hotels with free breakfast in Panama City

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Panama City Hotel Reviews

Frequently asked questions

Looking to vacation at a spa hotel in Panama City?
Forget the stress of everyday life and book yourself a hotel with a spa. Travelers highly recommend Panama City for its array of shops and gourmet restaurants—your day tour starts here. Be sure to enjoy the cafes during your stay. Spa hotels are a great way to break away from your routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Panama City?
Megapolis Hotel Panamá is a top luxury spa hotel featuring 3 bars, a casino, a shopping mall, and a fitness center. Enjoy a facial, body scrub, or detox wrap at the onsite spa. Other popular spa hotels in Panama City include Waymore Hotel Spa & Casino and Decapolis Hotel Panama City.
How many spa hotels are there in Panama City?
Expedia has 21 spa hotels to choose from in Panama City.
What's there to see and do in Panama City?
Enjoy Panama City with a stop at Albrook Shopping Mall, Via Espana, and Iglesia del Carmen. If you have a little extra time during your trip, you might want to check out Uruguay Street and Avenida Balboa.
What is a Panama City spa hotel?
Spa hotels in Panama City have full on-site spas which offer services like massages and a range of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are great for rest, rejuvenation, and relaxation.