Find Resorts & Hotels with Spas in Panama City

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Our top choices for Panama City hotels with a spa

1. Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2,246 reviews)
  • cleanliness
    Unwind with hot stone massages and facials at this hotel spa with pool views and plush treatment rooms.
The price is AED 355
AED 391 total
includes taxes & fees
22 Nov - 23 Nov
Plaza Paitilla Inn Hotel

2. Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
Tocumen Airport
8.6 out of 10, Excellent, (1,817 reviews)
  • cleanliness
    Rejuvenate at this tranquil resort with pampering spa services, a stunning pool with swim-up bar, and lush gardens perfect for unwinding.
The price is AED 398
AED 437 total
includes taxes & fees
24 Nov - 25 Nov
Riande Aeropuerto Hotel & Casino

3. Decapolis Hotel Panama City

Decapolis Hotel Panama City
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,746 reviews)
  • cleanliness
    Revive in Panama's premier hotel spa with Turkish hammam, hydrotherapy, and multiple treatment rooms for total rejuvenation.
The price is AED 377
AED 418 total
includes taxes & fees
16 Dec - 17 Dec
Decapolis Hotel Panama City

4. Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
San Francisco
8.6 out of 10, Excellent, (1,883 reviews)
  • cleanliness
    Immerse in therapeutic bliss with 2 spa rooms, steam, and sauna at this full-service wellness hotel.
The price is AED 553
AED 609 total
includes taxes & fees
23 Nov - 24 Nov
Megapolis Hotel Panamá

5. Hotel San Felipe

Hotel San Felipe
4.0 star property
Casco Viejo
9.4 out of 10, Exceptional, (479 reviews)
  • cleanliness
    Recharge with daily aromatherapy, couples massages, and a garden-view spa at this stylish Panama City retreat.
The price is AED 577
AED 635 total
includes taxes & fees
16 Nov - 17 Nov
Hotel San Felipe

6. Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
Casco Viejo
9.8 out of 10, Exceptional, (774 reviews)
  • cleanliness
    Indulge in a waterfront spa retreat with outdoor treatment areas and hot stone massages at this beautifully restored Colonial hotel.
The price is AED 1,388
AED 1,527 total
includes taxes & fees
17 Nov - 18 Nov
Sofitel Legend Casco Viejo, Panama City

7. Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
4.0 star property
Casco Viejo
9.2 out of 10, Wonderful, (1,010 reviews)
  • cleanliness
    Discover revitalizing massages and soothing facials at this historic hotel with a rooftop pool and steam room in Panama's vibrant center.
The price is AED 616
AED 678 total
includes taxes & fees
29 Nov - 30 Nov
Central Hotel Panama Casco Viejo

8. Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
4.0 star property
Bella Vista
7.8 out of 10, Good, (1,002 reviews)
  • cleanliness
    Tranquil spa sanctuary with deep-tissue massages and couples' treatments awaits in upscale Panama hotel.
The price is AED 347
AED 382 total
includes taxes & fees
1 Dec - 2 Dec
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

9. Hilton Panama

Hilton Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,000 reviews)
  • cleanliness
    Indulge in blissful wellness at this Panama hotel with a full-service spa, casino, and outdoor pool to restore and rejuvenate.
The price is AED 855
AED 941 total
includes taxes & fees
13 Dec - 14 Dec
Hilton Panama

10. Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
5.0 star property
Casco Viejo
9.8 out of 10, Exceptional, (380 reviews)
  • cleanliness
    Soak in this colonial retreat's full-service spa sanctuary with rooftop pool and historic charm, creating a rejuvenating wellness escape.
The price is AED 1,202
AED 1,322 total
includes taxes & fees
1 Dec - 2 Dec
Hotel La Compañía Casco Antiguo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Choose what matters most at spa hotels in Panama City

Spa hotels with pools in Panama City

Spa hotels with hot tubs in Panama City

Spa hotels with free breakfast in Panama City

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Panama City Hotel Reviews