A coastal cityscape with high-rise buildings, a marina, and a clear blue sky.

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Our top choices for Panama City hotels with a spa

1. Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
San Francisco
8.4 out of 10, Very Good, (1,633 reviews)
  • cleanliness
    Immerse in therapeutic bliss with 2 spa rooms, steam, and sauna at this full-service wellness hotel.
The price is AED 639
AED 703 total
includes taxes & fees
28 Aug - 29 Aug
Megapolis Hotel Panamá

2. Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2,225 reviews)
  • cleanliness
    Unwind with hot stone massages and facials at this hotel spa with pool views and plush treatment rooms.
The price is AED 379
AED 417 total
includes taxes & fees
24 Aug - 25 Aug
Plaza Paitilla Inn Hotel

3. Decapolis Hotel Panama City

Decapolis Hotel Panama City
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,710 reviews)
  • cleanliness
    Revive in Panama's premier hotel spa with Turkish hammam, hydrotherapy, and multiple treatment rooms for total rejuvenation.
The price is AED 440
AED 484 total
includes taxes & fees
7 Aug - 8 Aug
Decapolis Hotel Panama City

4. Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
4.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,051 reviews)
  • cleanliness
    Immerse in a full-service spa retreat with 4 treatment rooms, sauna, and steam room at this modern bed & breakfast.
The price is AED 386
AED 424 total
includes taxes & fees
1 Sep - 2 Sep
Waymore Hotel Spa & Casino

5. Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,060 reviews)
  • cleanliness
    Rejuvenating spa sanctuary with indoor pool offers daily pampering in Panama's central district.
The price is AED 595
AED 654 total
includes taxes & fees
9 Aug - 10 Aug
Las Americas Golden Tower Panama

6. Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
Tocumen
8.4 out of 10, Very Good, (1,815 reviews)
  • cleanliness
    Rejuvenate at this tranquil resort with pampering spa services, a stunning pool with swim-up bar, and lush gardens perfect for unwinding.
The price is AED 434
AED 477 total
includes taxes & fees
17 Aug - 18 Aug
Riande Aeropuerto Hotel & Casino

7. JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,002 reviews)
  • cleanliness
    Immerse in waterfront tranquility with bay views, rejuvenating in-room massages, and four outdoor pools for a complete spa getaway.
The price is AED 1,026
AED 1,128 total
includes taxes & fees
28 Aug - 29 Aug
JW Marriott Panama

8. Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
4.5 star property
Bella Vista
8.8 out of 10, Excellent, (1,004 reviews)
  • cleanliness
    Luxurious spa retreat in the heart of Panama with 10 treatment rooms and pampering Ayurvedic services for a complete wellness journey.
The price is AED 569
AED 626 total
includes taxes & fees
5 Aug - 6 Aug
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

9. Hilton Panama

Hilton Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1,003 reviews)
  • cleanliness
    Indulge in blissful wellness at this Panama hotel with a full-service spa, casino, and outdoor pool to restore and rejuvenate.
The price is AED 870
AED 957 total
includes taxes & fees
4 Sep - 5 Sep
Hilton Panama

10. Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive
4.0 star property
Veracruz
7.6 out of 10, Good, (1,044 reviews)
  • cleanliness
    Rejuvenating oceanfront retreat with couples spa suites and hydrotherapy treatments awaits at this beachfront haven with 4 pools.
The price is AED 1,000
AED 1,000 total
includes taxes & fees
23 Aug - 24 Aug
Dreams Playa Bonita Panama - All Inclusive
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Choose what matters most at spa hotels in Panama City

Spa hotels with pools in Panama City

Spa hotels with hot tubs in Panama City

Spa hotels with free breakfast in Panama City

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Panama City Hotel Reviews

Frequently asked questions

Looking to vacation at a spa hotel in Panama City?
Forget the stress of everyday life and book yourself a hotel with a spa. Travelers highly recommend Panama City for its array of shops and gourmet restaurants—your day tour starts here. Be sure to enjoy the cafes during your stay. Spa hotels are a great way to break away from your routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Panama City?
Megapolis Hotel Panamá is a top luxury spa hotel featuring 3 bars, a casino, a shopping mall, and a fitness center. Enjoy a facial, body scrub, or detox wrap at the onsite spa. Other popular spa hotels in Panama City include Waymore Hotel Spa & Casino and W Panama.
How many spa hotels are there in Panama City?
Expedia has 21 spa hotels to choose from in Panama City.
What's there to see and do in Panama City?
Enjoy Panama City with a stop at Albrook Shopping Mall, Via Espana, and Iglesia del Carmen. If you have a little extra time during your trip, you might want to check out Uruguay Street and Avenida Balboa.
What is a Panama City spa hotel?
Spa hotels in Panama City have full on-site spas which offer services like massages and a range of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are great for rest, rejuvenation, and relaxation.