Find Resorts & Hotels with Spas in Panama City
Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Check availability on Panama City Resorts & Hotels with Spas
Pick from 45 Panama City Resorts & Hotels with Spas and compare room rates, reviews, and availability. Most hotels are fully refundable.
Bristol Panama, a Registry Collection Hotel
Bristol Panama, a Registry Collection Hotel
9.2 out of 10, Wonderful, (1004)
The price is AED 711
AED 782 total
includes taxes & fees
28 Jun - 29 Jun
American Trade Hotel
American Trade Hotel
9.2 out of 10, Wonderful, (396)
The price is AED 1,062
AED 1,168 total
includes taxes & fees
18 Jun - 19 Jun
Hotel Riu Plaza Panama
Hotel Riu Plaza Panama
9.0 out of 10, Wonderful, (2530)
The price is AED 422
AED 465 total
includes taxes & fees
16 Jun - 17 Jun
Waldorf Astoria Panama
Waldorf Astoria Panama
9.0 out of 10, Wonderful, (945)
The price is AED 673
AED 740 total
includes taxes & fees
3 Jul - 4 Jul
TRYP by Wyndham Panamá Centro
TRYP by Wyndham Panamá Centro
9.0 out of 10, Wonderful, (1009)
The price is AED 284
AED 312 total
includes taxes & fees
10 Jun - 11 Jun
Best Western Plus Panama Zen Hotel
Best Western Plus Panama Zen Hotel
9.0 out of 10, Wonderful, (680)
The price is AED 290
AED 319 total
includes taxes & fees
23 Jun - 24 Jun
Central Hotel Panama Casco Viejo
Central Hotel Panama Casco Viejo
9.0 out of 10, Wonderful, (690)
The price is AED 818
AED 900 total
includes taxes & fees
10 Jun - 11 Jun
Las Americas Golden Tower Panama
Las Americas Golden Tower Panama
8.8 out of 10, Excellent, (887)
The price is AED 414
AED 456 total
includes taxes & fees
15 Jun - 16 Jun
JW Marriott Panama
JW Marriott Panama
8.8 out of 10, Excellent, (1007)
The price is AED 871
AED 943 total
includes taxes & fees
23 Jun - 24 Jun
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Recent reviews of Panama City hotelsExpedia verified reviews
5/5 Excellent
"Staff very professional and helpful."
A verified traveler stayed at Decapolis Hotel Panama City
Posted 1 day ago
Top neighborhoods for Resorts & Hotels with Spas
- Resorts & Hotels with Spas in Casco Viejo
- Resorts & Hotels with Spas in Bella Vista
- Resorts & Hotels with Spas in El Cangrejo
- Resorts & Hotels with Spas in San Francisco
- Resorts & Hotels with Spas in Calidonia
- Resorts & Hotels with Spas in Punta Paitilla
- Resorts & Hotels with Spas in Punta Pacifica
- Resorts & Hotels with Spas in Costa del Este
- Resorts & Hotels with Spas in Amador
More Hotel Options in Panama City
- Adventure Hotels (49)
- All-inclusive Hotel (4)
- Beach Hotels (31)
- Boutique Hotels (16)
- Business Hotels (97)
- Casinos (105)
- Cheap Hotels (56)
- Family Hotels (86)
- Golf Hotels (15)
- Green Hotels (3)
- Historic Hotels (111)
- Hotel Wedding Venues (38)
- Hotel with a Concierge (62)
- Hotels with Bars (93)
- Hotels with Early Check-in (4)
- Hotels with Free Parking (110)
- Hotels with Hot Tubs (24)
- Hotels with WiFi (141)
- Hotels with a Pool (88)
- Hotels with an Indoor Pool (1)
- Hotels with smoking rooms (39)
- Luxury Hotels (48)
- Pet-friendly Hotels (24)
- Romantic Hotels (20)
- Shopping Hotels (111)
- Ski Hotels (1)
- Waterpark Hotels (1)
- Winery Hotels (1)
More Accommodation Types in Panama City
- Apartments in Panamá Province (606)
- Vacation Homes in Panamá Province (50)
- Aparthotels in Panamá Province (37)
- Condo Rentals in Panamá Province (37)
- Hostels in Panamá Province (28)
- B&B in Panamá Province (15)
- Lodges in Panamá Province (8)
- Guest Houses in Panamá Province (6)
- Villas in Panamá Province (6)
- Farmstay in Panamá Province (2)
- Cabin Rentals in Panamá Province (2)
- RV Parks in Panamá Province (2)
- Resorts in Panamá Province (2)
- Castles in Panamá Province (1)
- Cottages in Panamá Province (1)
- Houseboats in Panamá Province (1)
- Inns in Panamá Province (1)
- Pensions in Panamá Province (1)
Hotels near popular Panama City Attractions
- Hotels near Albrook Shopping Mall
- Hotels near Multiplaza Pacific Mall
- Hotels near Amador Causeway
- Hotels near Avenida Balboa
- Hotels near Via Espana
- Hotels near Cinta Costera
- Hotels near El Dorado Mall
- Hotels near Miraflores Locks
- Hotels near Fuerte Amador Resort & Marina
- Hotels near Iglesia del Carmen
Panama City Hotels by Star Rating
Explore more hotels
- Ramada Plaza By Wyndham Panama Punta Pacífica
- Marriott Panama Hotel
- Hospedium Princess Hotel Panama
- TRYP by Wyndham Panamá Centro
- Sofitel Legend Casco Viejo, Panama City
- Hilton Panama
- Holiday Inn Panama Distrito Financiero, an IHG Hotel
- Hotel Ojos del Rio
- Riande Urban Hotel
- AC Hotel by Marriott Panama City
- The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
- Radisson Hotel Panama Canal
- MARINN PLACE Financial District
- Residence Inn by Marriott Panama City
- Studio Coliving
- Hotel El Panama by Faranda Grand, a member of Radisson Individuals
- Central Hotel Panama Casco Viejo
- The Executive Hotel
- Sortis Hotel, Spa & Casino, Autograph Collection
- Sheraton Grand Panama
Expedia's Latest Trends
Hotels
Flights
Flights to EasthopeFlights to BroadstoneFlights to AtchamFlights to DetchantFlights to BranscombeFlights to TywardreathFlights to TredunnockFlights to TingrithFlights to BoxgroveFlights to StokesleyFlights to Great SalkeldFlights to CriggionFlights to PonsanoothFlights to HacilarFlights to Down ThomasFlights to RowtonFlights to BrockworthFlights to DartingtonFlights to BosburyFlights to BostanFlights to LochdonFlights to Toy's HillFlights to MarkyateFlights to AltarnunFlights to GuzelcehisarFlights to SirnakFlights to Skeyton