A tropical island with palm trees and a clear blue sky.

Vacation Homes in Panama

Compare and save
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
In two months
In three months
In four months

Top Cities in Panama

Our top choices for Panama vacation homes

1. Villas Residences by Playa Caracol Resorts

Villas Residences by Playa Caracol Resorts
3.5 star property
Punta Chame
8.0 out of 10, Very good, (9 reviews)
"The place was equipped, clean and amazing location, we truly enjoyed and will come back , thank you"
United States
Saro
The price is AED 291
AED 482 total
includes taxes & fees
1 Oct - 2 Oct
Villas Residences by Playa Caracol Resorts

2. Ventanas del Mar by Playa Caracol Resort

Ventanas del Mar by Playa Caracol Resort
4.0 star property
Punta Chame
10.0 out of 10, Exceptional, (4 reviews)
"Buen lugar para pasar en familia, excelentes instalaciones y espectacular vista. Sin duda regresaremos."
United States
Linda
The price is AED 243
AED 433 total
includes taxes & fees
8 Oct - 9 Oct
Ventanas del Mar by Playa Caracol Resort

3. Surfari Bocas

Surfari Bocas
2.5 star property
Bocas del Toro
9.0 out of 10, Wonderful, (69 reviews)
"Lost our key partying about in Bocas town, came back to the hotel at 3am and the owner (great guy) let us back in!! Our savior and the accommodations (AC in particular) were very nice. Would 100% stay here again."
United States
Carter
The price is AED 102
AED 113 total
includes taxes & fees
30 Sep - 1 Oct
Surfari Bocas

4. Casa Nero Panama, Boca Chica, Chiriqui, Playa Hermosa, infinity pool, large garden

Casa Nero Panama, Boca Chica, Chiriqui, Playa Hermosa, infinity pool, large garden
Boca Chica
10.0 out of 10, Exceptional, (2 reviews)
"The property is beautiful, peaceful and well appointed. We enjoyed the pool and the hummingbirds that visit the flowers throughout the day. The kitchen is well stocked with all the equipment you need to prepare meals. I'd stay here again - no hesitation!"
United States
Mary S.
Casa Nero Panama, Boca Chica, Chiriqui, Playa Hermosa, infinity pool, large garden

5. Brand NEW Home Over on the Water

Brand NEW Home Over on the Water
Bocas del Toro
8.6 out of 10, Excellent, (7 reviews)
"The stay was good. We enjoyed the water, snorkeling and using the water board. "
United States
Sandy K.
The price is AED 149
AED 225 total
includes taxes & fees
30 Sep - 1 Oct
Brand NEW Home Over on the Water

6. Private Villa at Red Frog Beach Resort

Private Villa at Red Frog Beach Resort
Red Frog Beach
9.8 out of 10, Exceptional, (10 reviews)
"Gorgeous, spacious Villa at an absolutely beautiful resort. We loved the beaches and beach bars/restaurants. Brett is a responsive and helpful host. Shout out to Oliver at Red Frog who treated us as valued guests even though we rented through VRBO. Overall we had a wonderful vacation."
Canada
Angela B.
Private Villa at Red Frog Beach Resort

7. Aires frescos de Boquete

Aires frescos de Boquete
3.0 star property
Alto Boquete
8.0 out of 10, Very good, (6 reviews)
"I stayed there for 13 nights during a move to Panama. A real nice family run business. It was a great experience. The property is very well kept and super clean. The staff was super friendly and very timely with any questions I had. I had a small efficiency and there is a nice grocery store one block away. Can’t say enough and I would certainly recommend AIRES FRESCO to my friends and family. "
United States
David
The price is AED 163
AED 182 total
includes taxes & fees
4 Oct - 5 Oct
Aires frescos de Boquete

8. Susan Fish Camp in Playa Morrillo, Veraguas

Susan Fish Camp in Playa Morrillo, Veraguas
Morrillo
10.0 out of 10, Exceptional, (9 reviews)
"Fantastic place to stay in paradise! Look no further...this is the only place to stay if you're heading to Playa Morrillo area! "
United States
David M.
Susan Fish Camp in Playa Morrillo, Veraguas

9. Perfect for Families, Surfers and Nature-Lovers!!

Perfect for Families, Surfers and Nature-Lovers!!
Bocas del Toro
9.4 out of 10, Exceptional, (53 reviews)
"Loved the deck with ocean views and beautiful flowers! Enjoyed the close by restaurant and Skulleys."
United States
elizabeth k.
Perfect for Families, Surfers and Nature-Lovers!!

10. Downtown Villa with Private Pool & Bar

Downtown Villa with Private Pool & Bar
Bella Vista
10.0 out of 10, Exceptional, (2 reviews)
"The villa was perfect for me and my group of friends! Exactly as described in the pictures, great location, great host. Would recommend"
United States
Joe C.
Downtown Villa with Private Pool & Bar

11. Boquete Luxury: Chic & Serene Home, Walk to Town & Amenities

Boquete Luxury: Chic & Serene Home, Walk to Town & Amenities
Boquete
10.0 out of 10, Exceptional, (14 reviews)
"Stunning home, quiet and peaceful! We loved our stay here, two weeks was not enough. We are planning to return next year. We were going to rent a car but did not find it necessary as we could walk everywhere. Very highly recommend this home!"
United States
JoAnne L.
The price is AED 810
AED 1,060 total
includes taxes & fees
30 Sep - 1 Oct
Boquete Luxury: Chic & Serene Home, Walk to Town & Amenities

12. Paradise House, Boquete - Hiking, Birding, Coffee! Walk to town.

Paradise House, Boquete - Hiking, Birding, Coffee! Walk to town.
Bajo Boquete
9.8 out of 10, Exceptional, (14 reviews)
"Easy peezy to access, owner did a great job getting us oriented and settled in. Our stay was super relaxing, enjoyed the Boquete area, the facilities at Valle Escondido Resort, and the residence was well kept, modern, and clean. "
United States
Jeremy T.
Paradise House, Boquete - Hiking, Birding, Coffee! Walk to town.

13. A entire beach house in front of the Pacific for nature-loving families!

A entire beach house in front of the Pacific for nature-loving families!
San Lorenzo
10.0 out of 10, Exceptional, (9 reviews)
"The house and pool was exactly what we expected (perfect). The owner Marc André, was alway's available and kind. We enjoyed every moment of our stay."
Canada
Terri P.
A entire beach house in front of the Pacific for nature-loving families!

14. Jacuzy, pool and lake at the same house.

Jacuzy, pool and lake at the same house.
Colon
7.4 out of 10, Good, (3 reviews)
"Great. Please take care of the cat"
United States
KENNETH E.
Jacuzy, pool and lake at the same house.

15. Beachfront House at La Vida Resort

Beachfront House at La Vida Resort
3.0 star property
Bastimentos
8.6 out of 10, Excellent, (4 reviews)
"The beach,ocean and cottage was beautiful."
Canada
Michael
Beachfront House at La Vida Resort

16. Bocas Villas - Private Acqua Villas

Bocas Villas - Private Acqua Villas
Punta Caracol
9.2 out of 10, Wonderful, (7 reviews)
"The place is magical, right on the water, with a beautiful coral reef teeming with fish below for snorkeling. There's a small kayak for you to use; I used it to watch the sunset and it was beautiful. My wife loved this place. It's quiet, with a very peaceful vibe. It's about a 15-minute boat ride to get there. The owner, Philip, was very attentive and kind. This place definitely has a beautiful vibe; highly recommended."
United States
Daniel
The price is AED 281
AED 428 total
includes taxes & fees
30 Sep - 1 Oct
Bocas Villas - Private Acqua Villas

17. Luxury 3BR Pool, SPA & Golf Resort Near Canal 302

Luxury 3BR Pool, SPA & Golf Resort Near Canal 302
Cocoli
Luxury 3BR Pool, SPA & Golf Resort Near Canal 302

18. Chic 1-bedroom with WiFi and AC in enchanting Río Hato

Chic 1-bedroom with WiFi and AC in enchanting Río Hato
Río Hato
Chic 1-bedroom with WiFi and AC in enchanting Río Hato

19. Unique house with direct access to the beach, four bedrooms, balcony and design

Unique house with direct access to the beach, four bedrooms, balcony and design
Ciudad de Panamá
Unique house with direct access to the beach, four bedrooms, balcony and design

20. House with Pool and Ocean View - PH Costa Grande

House with Pool and Ocean View - PH Costa Grande
Nueva Gorgona
The price is AED 286
AED 517 total
includes taxes & fees
30 Sep - 1 Oct
House with Pool and Ocean View - PH Costa Grande
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Panama Hotel Reviews