Top Vacation Homes in Pemiscot County in 2026

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Top cities in Pemiscot County

A rock formation by a river with a bridge in the background.

Find vacation rentals that suit your style

Check prices for these dates

Next weekend

In two weeks

In one month

In two months

Our top choices for Pemiscot County vacation homes

A wooden interior with a dining table, chairs, a sofa, and a fireplace.

1. 3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters

Hornbeak

Steve H.

AED 1,573 total

includes taxes & fees

15 Nov - 16 Nov

A room with a large window, a table with woven placemats, and a hanging light fixture.

2. Duck Hunting, Fishing or Relaxing Family Vacation

Hornbeak

Karen H.

A modern kitchen with dark cabinets, stainless steel appliances, and a wooden floor.

3. Newly remodeled nice house in very safe and convenient neighborhood.

Dyersburg

Stephanie M.

4. Roberson Legacy Lakehouse Reelfoot Lake Pet friendly

Obion County

Brian L.

A kitchen area with a microwave above a shelf holding jars, a trash bin, and a snack shelf with chips and other snacks.

5. Comfy just like HOME- All the things!! Sportsmen welcome!

Dyersburg

AED 1,925 total

includes taxes & fees

30 Nov - 1 Dec

Three cabins with a gravel driveway and large trees in the background.

6. The Dragonfly - Sleeps up to 8, Lake views.

Hornbeak

Terry G.

A spacious wooden interior with a high ceiling, stone walls, and a dining area with multiple chairs and a table.

7. Stunning Cabin Truly On Reelfoot Lake_Private Hot Tub_Billiards

Hornbeak

Alenne G.

AED 1,886 total

includes taxes & fees

7 Dec - 8 Dec

A room with a large window overlooking a lake, wooden flooring, and two bar stools.

8. Lakeside Lodge Reelfoot cozy waterfront w greatview 3bdrm 2bth WIFI Bartop table

Hornbeak

Mike P.

A patio area with a covered seating arrangement, surrounded by well-maintained hedges and a variety of plants.

9. 3 bedrooms, 2 full bath, dining room, great room, den, beautiful outdoor patio.

Blytheville

Amanda H.

A living room with a sofa, coffee table, TV, and ceiling fan.

10. Peaceful tranquility 2-bedroom house with AC in friendly Blytheville

Blytheville

Jamie W.

View all properties

Top reviews in Pemiscot County

A spacious lobby with a modern design, featuring a seating area with patterned armchairs and a round table, a large window, and a fireplace with decorative wall art.

Drury Inn & Suites Hayti Caruthersville

Hayti

10/10 Excellent

William

A hotel room with two beds, a TV, a desk, and a wardrobe.

The Farmstead Hotel

Caruthersville

10/10 Excellent

Anonymous traveler

A hotel lobby with a reception desk, seating areas, and a hallway.

Hampton Inn Blytheville

Blytheville

10/10 Excellent

Marie

An indoor swimming pool with a clear waterline, a pool ladder, and lounge chairs along the side.

Holiday Inn Express Hotel & Suites Dyersburg by IHG

Dyersburg

10/10 Excellent

Geraldine

A hotel room with a large bed, a desk with a chair, a window with curtains, and a view of a parking lot.

Days Inn by Wyndham Dyersburg

Dyersburg

10/10 Excellent

Keith

Quality Inn Dyersburg I-155

Dyersburg

10/10 Excellent

David

A hotel room with two beds, a desk, a mirror, and a view of the city.

Motel 6 Dyersburg, TN

Dyersburg

10/10 Excellent

I didn't spend a lot of time in the room because of visiting with family but the room was nice and comfortable. The shower was AMAZING! Large and I want one just like it at home! The dresser and desk were a little large for the size of the room but very nice overall. My main problem with the Executive Inn and Suites is the lobby is so small that most of my family stays at the Hampton so they can visit in the evenings and at breakfast in the morning.

Rose M

A hotel room with two beds, a desk, a TV, and a window.

Deerfield Inn By Capital O Blytheville AR I55

Blytheville

10/10 Excellent

Corey

A modern kitchen with a stone backsplash, wooden cabinets, and a dining area with a black table and blue chairs.

Americas Best Value Inn Suites & Studios Blytheville by Sonesta

Blytheville

10/10 Excellent

Room was clean , beds comfortable , mini fridge very cold , kitchenette was nice to have ,staff was very friendly and attentive . Room was small but this is a motel type setting . Easy on the wallet . Traveling for work you can appreciate what you have . Breakfast was small but much better that the LaQuinta I had stayed at 3 hours back . No powdered eggs here ! Eggs cooked to order that’s hard to find at 90% of your larger hotels again staff was very attentive and cordial . Walmart and Starbucks...

Catherine