Find Resorts & Hotels with Spas in Pickens, SC

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Pickens Resorts & Hotels with Spas

Top Pickens Resorts & Hotels with Spas

Couples treatment rooms, body treatments, aromatherapy
Greystone Inn

Greystone Inn

3.5 star property
Lake Toxaway
  • Massages
  • Couples treatment rooms
9.4 out of 10, Exceptional, (85)
Lakeside serenity beckons at this mountain-cradled hotel where aromatherapy, reflexology, and Thai massages rejuvenate body and mind. Couples enjoy dedicated treatment rooms while active travelers appreciate tennis courts, seasonal pool, and water activities after savoring excellent on-property dining.
The price is AED 960
AED 1,196 total
includes taxes & fees
23 Nov - 24 Nov
Greystone Inn
Bar (on property)
Hotel Domestique

Hotel Domestique

4.0 star property
Travelers Rest
  • Massages
  • Sauna
  • Breakfast included
9.6 out of 10, Exceptional, (30)
Signature massage therapies transform tired muscles into renewed vitality at this boutique mountain retreat. Sauna sessions, tennis matches, and garden strolls complement spa treatments, while Restaurant 17 serves farm-fresh cuisine between wellness indulgences.
The price is AED 1,502
AED 1,652 total
includes taxes & fees
23 Nov - 24 Nov
Hotel Domestique
Spa
Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

4.0 star property
Greenville Downtown
  • Full-service spa
9.6 out of 10, Exceptional, (408)
Rushing water soundscapes enhance treatments at the full-service spa, creating a perfect harmony of nature and nurture. Professional staff deliver personalized care while scenic park surroundings offer peaceful walks after pampering sessions in this immaculate riverside haven.
The price is AED 988
AED 1,116 total
includes taxes & fees
30 Nov - 1 Dec
Grand Bohemian Lodge Greenville, Autograph Collection
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Black Friday Sale

Limited-time deals: Save up to 50% on select hotels
Book now

Top Pickens Hotel Reviews

Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center

10/10 Excellent
"So comfortable and relaxing "
Deborah 1-night trip
Posted 6 days ago
Embassy Suites Greenville Golf Resort & Conference Center

Explore a world of travel with Expedia

Frequently asked questions

Looking for a spa hotel in Pickens?
Soothe the senses with some time in one of our wonderful spa hotels. Check out the natural parks in Pickens - worth a picture or two! Hotels with spas are the perfect way to take a break from your daily routine and add a layer of luxury to your vacation.
What's there to see and do in Pickens?
Experience Pickens and visit Table Rock State Park, Table Rock, and Lake Keowee. If you have a little extra time during your trip, you might want to check out Irma Morris Museum of Fine Arts and Nine Times Forest.
What is a Pickens spa hotel?
Spa hotels in Pickens provide lodging and have an on-site spa offering services such as massages and body treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.