The Colosseum in Rome with its arches and surrounding gardens.

Find Business Hotels in Rome

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check availability on Rome Business Hotels

Tonight
16 Oct - 17 Oct
Tomorrow
17 Oct - 18 Oct
This weekend
16 Oct - 18 Oct
Next weekend
23 Oct - 25 Oct

Our top choices for Rome business-friendly hotels

1. UNA Hotels Decò Roma

UNA Hotels Decò Roma
Rome City Centre
Australia
Matthew
AED 400
AED 501 total
includes taxes & fees
8 Nov - 9 Nov
UNA Hotels Decò Roma

2. Hotel Scalinata di Spagna

Hotel Scalinata di Spagna
Rome City Centre
Canada
ANNA
AED 748
AED 872 total
includes taxes & fees
10 Nov - 11 Nov
Hotel Scalinata di Spagna

3. Hotel Nazionale

Hotel Nazionale
Rome City Centre
United Kingdom
Jacqueline
AED 703
AED 836 total
includes taxes & fees
16 Nov - 17 Nov
Hotel Nazionale

4. Hotel Delle Nazioni

Hotel Delle Nazioni
Rome City Centre
United States
eric
AED 715
AED 848 total
includes taxes & fees
8 Nov - 9 Nov
Hotel Delle Nazioni

5. Best Western Premier Hotel Royal Santina

Best Western Premier Hotel Royal Santina
Rome City Centre
United States
Danielle
AED 565
AED 684 total
includes taxes & fees
15 Nov - 16 Nov
Best Western Premier Hotel Royal Santina

6. Hotel Quirinale

Hotel Quirinale
Rome City Centre
United States
Kayleigh
AED 539
AED 655 total
includes taxes & fees
15 Nov - 16 Nov
Hotel Quirinale

7. Argentina Residenza Style Hotel

Argentina Residenza Style Hotel
Rome City Centre
United States
Nathaniel
AED 833
AED 978 total
includes taxes & fees
15 Nov - 16 Nov
Argentina Residenza Style Hotel

8. Hotel La Residenza

Hotel La Residenza
Rome City Centre
Canada
Sergio
AED 657
AED 784 total
includes taxes & fees
10 Nov - 11 Nov
Hotel La Residenza

9. Bettoja Hotel Massimo D'Azeglio

Bettoja Hotel Massimo D'Azeglio
Rome City Centre
United States
Nina
AED 627
AED 752 total
includes taxes & fees
16 Nov - 17 Nov
Bettoja Hotel Massimo D'Azeglio

10. Hotel Columbia

Hotel Columbia
Rome City Centre
United States
Diana
AED 531
AED 633 total
includes taxes & fees
15 Nov - 16 Nov
Hotel Columbia
View all properties

Top Rome Hotel Reviews

Hotel Quirinale

Hotel Quirinale

10/10 Excellent
"El Hotel tiene 150 años de fundado y está impecable, es una mezcla donde tienes mobiliarios de época con un servicio impecable. Las atenciones excelentes, el ambiente en el patio interior, sobre todo cuando hay música en vivo, buenísimo. Los desayunos son buenos y cenamos en el restaurante y fue muy bueno tanto el servicio como la cena en sí. El vino que pedimos buenísimo. La ubicación excelente, con línea de Metro en la esquina de la manzana del hotel y muy cerca de la Terminal de trenes Roma Termini. Excelente Hotel por donde quiera que lo mires."
MIGUELINA 3-night trip
Posted 13 hours ago
Hotel Quirinale
Best Western Hotel Rome Airport

Best Western Hotel Rome Airport

10/10 Excellent
"We stayed in the new wing and it was very comfortable. The rooms were a bit small but plenty of space for the one evening. The beds were comfortable and the the shower was fabulous."
Connie 1-night trip
Posted 13 hours ago
Best Western Hotel Rome Airport
Hilton Rome Airport

Hilton Rome Airport

10/10 Excellent
"This hotel was such a surprise! In the best way. We stayed there to be close to the airport for our trip out of Rome. It was beautiful and lovely. We spent time at the bar/restaurant and enjoyed our time there. It was more of an American style hotel, but that was fine, we were on our way back home. It was a pleasure to stay there. -The bed was ultra soft, and we had our best night's sleep there. -The food was great at the restaurant, but again, more American style with some Italian twists. -The location was right at the airport. You just walk over to your terminal. I would 100% recommend to anyway traveling back home from Rome!"
DEBORAH 1-night trip
Posted 14 hours ago
Hilton Rome Airport
Hotel Delle Nazioni

Hotel Delle Nazioni

10/10 Excellent
"Excellent location in Rome! We loved our stay at this hotel in Oct 2026. The location was perfect, right down the "road" from the Trevi Fountain, less than a block away. The staff was friendly. We had drinks at the restaurant, street level, great for people watching. We especially loved the rooftop bar for snacks and drinks. The man working there was fabulous. Our bedroom was comfy after a day of touring Rome. The breakfast was more than we could ever eat. We felt safe the entire time. What a great place. I would stay there again! It was very clean and modern. Shops were nearby, literally on the same block. Restaurants were everywhere, we never had to look for one."
DEBORAH 3-night trip
Posted 14 hours ago
Hotel Delle Nazioni
Hotel Artemide

Hotel Artemide

10/10 Excellent
"Beautiful hotel! We had an amazing stay!"
Crystal 2-night trip
Posted 3 days ago
Hotel Artemide

Explore a world of travel with Expedia