The Colosseum in Rome with its arches and surrounding gardens.

Find Adults Only Resorts & Hotels in Rome

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Rome Adults Only Resorts & Hotels

This weekend
30 Oct - 1 Nov
Next weekend
6 Nov - 8 Nov

Our top choices for Rome adults-only hotels

A nighttime view of a narrow street with buildings on either side, a potted plant with flowers, and two wine glasses on a ledge.

1. Palazzo Medusa

Palazzo Medusa
Rome City Centre
9.4 out of 10, Exceptional, (364 reviews)
"The location is good, near the river and walkable to the Vatican."
United States
Donald
The price is AED 363
AED 441 total
includes taxes & fees
22 Nov - 23 Nov
Palazzo Medusa
A cafe with wooden tables and chairs, a counter with pastries, and a view of the street outside.

2. Moderno Hotel Roma – Adults Only

Moderno Hotel Roma – Adults Only
4.0 star property
Rome City Centre
8.6 out of 10, Excellent, (306 reviews)
"Close to all amenities and restaurants. Front desk staff was super friendly"
Canada
Mike
The price is AED 404
AED 506 total
includes taxes & fees
19 Nov - 20 Nov
Moderno Hotel Roma – Adults Only
An arched doorway with a metal grille, wooden doors, and a small step leading into a building.

3. Vicolo del lupo Guesthouse

Vicolo del lupo Guesthouse
Rome City Centre
9.4 out of 10, Exceptional, (241 reviews)
"Absolutely perfect location. Extremely helpful and welcoming staff. Great communication before and during stay. Arranged private transportation from airport and to the cruise port for us. Made our stay easy and stress free."
United States
steven
The price is AED 518
AED 627 total
includes taxes & fees
8 Nov - 9 Nov
Vicolo del lupo Guesthouse
An outdoor dining area with a table set for two, a potted plant, and a lantern. In the background, there is a large dome and bell tower structure.

4. Lifestyle Suites Rome

Lifestyle Suites Rome
Rome City Centre
9.8 out of 10, Exceptional, (203 reviews)
"Staff was great the hotel was in a great location everything was wonderful"
United States
Sonia
The price is AED 919
AED 1,051 total
includes taxes & fees
15 Nov - 16 Nov
Lifestyle Suites Rome
A modern reception area with a marble reception desk, a seating area with chairs, and a large window with curtains.

5. Hotel Alex Square

Hotel Alex Square
3.0 star property
Rome City Centre
6.8 out of 10, (50 reviews)
"I loved having clean towels and room clean upon return. The breakfast was great and staff attending it was very friendly."
United States
Elizabeth
The price is AED 289
AED 367 total
includes taxes & fees
5 Nov - 6 Nov
Hotel Alex Square
A couple dining at a restaurant with a mural of a classical fountain and architecture in the background.

6. Dream Suite Trevi

Dream Suite Trevi
Rome City Centre
10.0 out of 10, Exceptional, (37 reviews)
"Wonderful location. Great staff. Lovely stay!"
United States
Julia A
The price is AED 825
AED 965 total
includes taxes & fees
20 Nov - 21 Nov
Dream Suite Trevi
A terrace with white chairs and a table, overlooking a historic building with a dome.

7. Hotel VM

Hotel VM
Vatican
8.4 out of 10, Very good, (71 reviews)
"Location, location, location and parking!!! Roof terrace with a view"
United States
Adam
The price is AED 290
AED 368 total
includes taxes & fees
22 Nov - 23 Nov
Hotel VM
A grand entrance with a double door, a tiled floor, and potted plants at the entrance.

8. Pantheonview - Luxury Suites

Pantheonview - Luxury Suites
Rome City Centre
8.6 out of 10, Excellent, (195 reviews)
"It was a lovely hotel in a very strategic area near the Pantheon. We loved it!"
United States
Sofia
The price is AED 633
AED 746 total
includes taxes & fees
9 Nov - 10 Nov
Pantheonview - Luxury Suites
A modern hotel room with a large bathtub, a bed with a view of a glass-enclosed shower area, and a mounted television.

9. Ripetta Relais

Ripetta Relais
Rome City Centre
8.6 out of 10, Excellent, (162 reviews)
"Love it"
United States
farid
Ripetta Relais
A view from a window overlooking a cobblestone street with parked cars and lush greenery.

10. Vinci House

Vinci House
Rome City Centre
9.8 out of 10, Exceptional, (30 reviews)
"Great walking tour route and restaurant recommendations from the host!"
United States
Peiwen
The price is AED 521
AED 623 total
includes taxes & fees
3 Nov - 4 Nov
Vinci House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Rome Hotel Reviews

Explore a world of travel with Expedia