An aerial view of a coastal city with a prominent central monument, dense urban buildings, and a rocky shoreline.

Search Vacation Homes in Santo Domingo

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
13 Nov - 15 Nov
In two months
25 Dec - 27 Dec
In three months
22 Jan - 24 Jan
In four months
19 Feb - 21 Feb

Our top choices for Santo Domingo vacation homes

A dining area with a wooden table and chairs, a black sofa, and a ceiling fan.

1. House by Aut. Las Américas 10 minutes from the airport

House by Aut. Las Américas 10 minutes from the airport
Los Frailes
The price is AED 595
AED 683 total
includes taxes & fees
31 Oct - 1 Nov
House by Aut. Las Américas 10 minutes from the airport
A living room with a white sofa, a glass coffee table, a wicker pendant light, and a view of the dining area through an archway.

2. Cozy and Quiet Corner to Rest

Cozy and Quiet Corner to Rest
Los Frailes
Cozy and Quiet Corner to Rest
Room

3. Room-malecon Cozy - Premium Plus 12

Room-malecon Cozy - Premium Plus 12
2.5 star property
Ciudad Universitaria
The price is AED 202
AED 283 total
includes taxes & fees
3 Nov - 4 Nov
Room-malecon Cozy - Premium Plus 12
A traditional room with a patterned tile floor, a wooden door, a small table with chairs, and a shelf with plants.

4. Comfort & ancient beauty meet

Comfort & ancient beauty meet
Zona Colonial
8.0 out of 10, Very good, (3 reviews)
"Love the location"
United States
tysean
Comfort & ancient beauty meet
A wooden outdoor seating area with wicker furniture and a staircase.

5. Luxury Morden house with Jacuzzi Zona Colonial.!

Luxury Morden house with Jacuzzi Zona Colonial.!
Zona Colonial
10.0 out of 10, Exceptional, (7 reviews)
"Everything was perfect, the host was very friendly and accessible. I definitely will stay again."
United States
Robert J.
Luxury Morden house with Jacuzzi Zona Colonial.!
A modern outdoor living space with a dining area, seating, and a city view.

6. ★Designer LOFT 1BR Piantini | CityViews-YellowKey

★Designer LOFT 1BR Piantini | CityViews-YellowKey
Piantini
10.0 out of 10, Exceptional, (5 reviews)
"It was amazing"
United States
Miguel Ángel M.
The price is AED 209
AED 466 total
includes taxes & fees
2 Nov - 3 Nov
★Designer LOFT 1BR Piantini | CityViews-YellowKey
A patio with string lights, a table, and chairs.

7. Acogedora Casita en el corazón de la Zona Colonial

Acogedora Casita en el corazón de la Zona Colonial
Zona Colonial
Acogedora Casita en el corazón de la Zona Colonial
A bedroom with a bed, a desk with a chair, a ceiling fan, and an air conditioning unit.

8. Short Term Rooms in Central Zone of the City

Short Term Rooms in Central Zone of the City
Gascue
6.6 out of 10, (4 reviews)
"The room is OK, very spacious, and very comodable. Only issue is that the wifi is intermittent."
United States
Benjamin
Short Term Rooms in Central Zone of the City
A modern dining area with a glass table and grey upholstered chairs, a wooden accent wall, and a view of a balcony with a railing.

9. Santo Domingo GETAWAY OASIS

Santo Domingo GETAWAY OASIS
Ciudad Universitaria
10.0 out of 10, Exceptional, (1 review)
"Awesome stay would stay here again highly recommend "
United States
Moolah E.
The price is AED 239
AED 496 total
includes taxes & fees
31 Oct - 1 Nov
Santo Domingo GETAWAY OASIS
A corridor with white tiled flooring, ornate columns, and a metal railing.

10. Heart of DR, 20 Min from Airport

Heart of DR, 20 Min from Airport
Santo Domingo Este
10.0 out of 10, Exceptional, (2 reviews)
"The place is quiet and Miguel the person who assist you with the check in he’s so nice"
United States
Yaisel L.
Heart of DR, 20 Min from Airport
A modern living room with a sofa, a glass coffee table, a television, and a ceiling fan.

11. Modern Apartment in Santo Domingo – Near the Colonial District & Malecón

Modern Apartment in Santo Domingo – Near the Colonial District & Malecón
Gascue
Modern Apartment in Santo Domingo – Near the Colonial District & Malecón
A hotel room with a bed, a TV, a dresser, and a window with curtains.

12. Short Term Studio Apartment in Gascue, Central Zone of the City

Short Term Studio Apartment in Gascue, Central Zone of the City
Gascue
8.8 out of 10, Excellent, (3 reviews)
"Very friendly staff. The room was clean and comfortable. "
United States
Jorge R.
Short Term Studio Apartment in Gascue, Central Zone of the City
Point of interest

13. Room-malecon Cozy Private Room 6

Room-malecon Cozy Private Room 6
3.0 star property
Ciudad Universitaria
4.0 out of 10, (1 review)
"There was no hot water option in the shower or sink house cleaning was extra and towels were not regularly available had to ask for new ones and they didn’t want to give me more then one at a time "
United States
Matthew
The price is AED 132
AED 201 total
includes taxes & fees
1 Nov - 2 Nov
Room-malecon Cozy Private Room 6
A modern living room with a white sofa, red chair, glass coffee table, and a ceiling fan.

14. Rentamos Aparta Estudio for short or long stay

Rentamos Aparta Estudio for short or long stay
Gascue
The price is AED 250
AED 324 total
includes taxes & fees
28 Nov - 29 Nov
Rentamos Aparta Estudio for short or long stay
A modern outdoor living space with a dining area, seating, and a city view.

15. Getaway 1BR-WiFi-AC-View-Gym-BlueMall-YellowKey

Getaway 1BR-WiFi-AC-View-Gym-BlueMall-YellowKey
Piantini
Getaway 1BR-WiFi-AC-View-Gym-BlueMall-YellowKey
A modern living room with a ceiling fan, a flat-screen TV, a sofa, a coffee table, and decorative items on shelves.

16. 2-Bedroom Family Apartment in Downtown with Gym and Rooftop Terrace

2-Bedroom Family Apartment in Downtown with Gym and Rooftop Terrace
Downtown Santo Domingo
10.0 out of 10, Exceptional, (4 reviews)
"This apartment has all that you need, spacious, clean, modern and welcoming.The location is perfect and easy to get around Santo Domingo. Great communication with host."
United States
José J.
2-Bedroom Family Apartment in Downtown with Gym and Rooftop Terrace
A modern hotel room with a kitchen area, a large mirror, and a balcony with curtains.

17. In The City Center Modern Apartment! Pool&Gym

In The City Center Modern Apartment! Pool&Gym
Downtown Santo Domingo
9.0 out of 10, Wonderful, (7 reviews)
"Great location! Around a few restaurants and stores an uber to almost every location. Soler the front guy was amazing and friendly. "
United States
Lucia M.
In The City Center Modern Apartment! Pool&Gym
A rooftop terrace with a hot tub, lounge chairs, and a canopy seating area.

18. Regatta Living Prime Location, Stunning Amenities

Regatta Living Prime Location, Stunning Amenities
Piantini
Regatta Living Prime Location, Stunning Amenities
A modern dining area with a glass table, chairs, and a city view.

19. Upscale 1BR apartment near Blue mall with rooftop by Yellowkey

Upscale 1BR apartment near Blue mall with rooftop by Yellowkey
Piantini
10.0 out of 10, Exceptional, (2 reviews)
"Great weekend getaway. Would highly recommend."
United States
Andres A.
Upscale 1BR apartment near Blue mall with rooftop by Yellowkey
A modern outdoor living space with a dining area, seating, and a city view.

20. Armonia Piantini, A/C, Wifi, Smart tv-YellowKey

Armonia Piantini, A/C, Wifi, Smart tv-YellowKey
Piantini
10.0 out of 10, Exceptional, (1 review)
"Great stay"
United States
Christopher R.
Armonia Piantini, A/C, Wifi, Smart tv-YellowKey
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Santo Domingo Hotel Reviews

whala! boca chica - All inclusive

whala! boca chica - All inclusive

10/10 Excellent
"On a beautiful beach"
David 9-night trip
Posted 4 hours ago
whala! boca chica - All inclusive

Explore a world of travel with Expedia