Find hotels near Santo Domingo Square, Cartagena from AED 337

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santo Domingo Square hotels

Hotel Quadrifolio

Hotel Quadrifolio
4.5 star property
Cartagena Centro, 0.2 km from Santo Domingo Square
10.0 out of 10, Exceptional, (163)
"Super cute hotel in the heart of the walled city! Enjoyed the complimentary birthday cake in my room and the staff were super sweet and attentive! Their level of care needs to be studied as it’s hard to find these days. "
United States
Chiron
The price is AED 1,839
AED 1,839 total
11 Jan - 12 January 2026
Hotel Quadrifolio

Hotel Casa del Gobernador

Hotel Casa del Gobernador
4.5 star property
Cartagena Centro, 0.2 km from Santo Domingo Square
9.8 out of 10, Exceptional, (99)
"Beautiful place to stay in historic distric of Cartagena "
United States
Jorge
Hotel Casa del Gobernador

Alfiz Hotel Boutique

Alfiz Hotel Boutique
3.0 star property
Cartagena Centro, 0.3 km from Santo Domingo Square
9.6 out of 10, Exceptional, (186)
"This hotel is absolutely lovely, including the employees. They go above and beyond to take care of their guests. We will definitely stay here again!"
United States
Alison
Alfiz Hotel Boutique

Sophia Hotel By OxoHotel

Sophia Hotel By OxoHotel
4.0 star property
Cartagena Centro, 0.2 km from Santo Domingo Square
9.6 out of 10, Exceptional, (601)
"Amazing stay highly recommend "
United States
Michael
Sophia Hotel By OxoHotel

Casa La Cartujita

Casa La Cartujita
4.0 star property
San Diego, 0.5 km from Santo Domingo Square
9.8 out of 10, Exceptional, (171)
"Cute boutique hotel, great room , service and breakfast. "
United States
Kiranmayi
The price is AED 544
AED 544 total
23 Dec - 24 Dec
Casa La Cartujita

Amarla Boutique Hotel Cartagena

Amarla Boutique Hotel Cartagena
3.5 star property
Cartagena Centro, 0.1 km from Santo Domingo Square
9.6 out of 10, Exceptional, (54)
"The staff was freindly, helpful, gracious ... knew our names throughout our stay. We looked forward to breakfast every day! The ONLY down side was that the pool wasn't open. Otherwise we were comfortable and in awe of the beautiful Amarla."
United States
jennifer
Amarla Boutique Hotel Cartagena

Hotel Casa La Mantilla by Faranda Boutique

Hotel Casa La Mantilla by Faranda Boutique
4.0 star property
Cartagena Centro, < 0.1 km from Santo Domingo Square
9.4 out of 10, Exceptional, (139)
"Very nice, good and quiet hotel. I love it! I recommend it100%"
United States
Andres
The price is AED 623
AED 623 total
12 Jan - 13 January 2026
Hotel Casa La Mantilla by Faranda Boutique

Moet Cartagena Hotel Boutique - Adults Only

Moet Cartagena Hotel Boutique - Adults Only
4.5 star property
San Diego, 0.3 km from Santo Domingo Square
9.4 out of 10, Exceptional, (95)
"Very friendly and efficient staff Clean property Closed to interest areas"
United States
Luis
Moet Cartagena Hotel Boutique - Adults Only

Casa Claver Loft Boutique Hotel

Casa Claver Loft Boutique Hotel
4.0 star property
Cartagena Centro, 0.2 km from Santo Domingo Square
9.6 out of 10, Exceptional, (577)
"The property was gorgeous and the staff was awesome. Had a great stay. "
United States
Ibrahim
The price is AED 1,052
AED 1,052 total
18 Dec - 19 Dec
Casa Claver Loft Boutique Hotel

Movich Hotel Cartagena de Indias

Movich Hotel Cartagena de Indias
4.0 star property
Cartagena Centro, 0.2 km from Santo Domingo Square
9.4 out of 10, Exceptional, (551)
"The room was clean and well appointed but just a little bit musty when we entered. I loved the location of this hotel it was near to everything no need for cabs. The staff were very helpful and friendly. The food was just meh, the menu could be more varied especially breakfast. We loved the rooftop restaurant for the view and atmosphere. I would stay there again but just eat out more. "
United States
Desalyn Teresa
The price is AED 1,513
AED 1,513 total
13 Dec - 14 Dec
Movich Hotel Cartagena de Indias

Hotel Casa Don Luis by Faranda Boutique, a member of Radisson Individuals

Hotel Casa Don Luis by Faranda Boutique, a member of Radisson Individuals
4.0 star property
Cartagena Centro, 0.2 km from Santo Domingo Square
9.4 out of 10, Exceptional, (225)
"The staff was great supper friendly and helpful. Breakfast and restaurant was delicious."
United States
Joe
The price is AED 1,091
AED 1,091 total
13 Dec - 14 Dec
Hotel Casa Don Luis by Faranda Boutique, a member of Radisson Individuals

Bastión Luxury Hotel

Bastión Luxury Hotel
4.5 star property
San Diego, 0.4 km from Santo Domingo Square
9.6 out of 10, Exceptional, (1002)
"Beautiful property "
Canada
Linda
The price is AED 979
AED 979 total
15 Dec - 16 Dec
Bastión Luxury Hotel

Cinco Quintas Hotel Boutique

Cinco Quintas Hotel Boutique
4.0 star property
Cartagena Centro, 0.3 km from Santo Domingo Square
9.4 out of 10, Exceptional, (233)
"Great Place"
Canada
James
The price is AED 660
AED 660 total
24 Dec - 25 Dec
Cinco Quintas Hotel Boutique

Hotel Boutique Casa del Coliseo

Hotel Boutique Casa del Coliseo
4.5 star property
Cartagena Centro, 0.3 km from Santo Domingo Square
9.4 out of 10, Exceptional, (304)
"The staff was very helpful. "
United States
thomas
The price is AED 904
AED 904 total
17 Dec - 18 Dec
Hotel Boutique Casa del Coliseo

Casa del Arzobispado Hotel

Casa del Arzobispado Hotel
4.0 star property
Cartagena Centro, 0.2 km from Santo Domingo Square
9.4 out of 10, Exceptional, (320)
"Fantastic staff and very friendly, very close to everything "
Canada
Sahar
Casa del Arzobispado Hotel

Charleston Santa Teresa Cartagena

Charleston Santa Teresa Cartagena
5.0 star property
Cartagena Centro, 0.3 km from Santo Domingo Square
9.4 out of 10, Exceptional, (779)
"Excellent service, food and amenities "
United States
Alejandra
The price is AED 1,261
AED 1,261 total
15 Dec - 16 Dec
Charleston Santa Teresa Cartagena

Casa Noa Colonial Rooms

Casa Noa Colonial Rooms
2.5 star property
Cartagena Centro, 0.3 km from Santo Domingo Square
9.2 out of 10, Wonderful, (163)
"The room was comfortable and the area was very convenient !"
United States
Pierre
The price is AED 337
AED 337 total
25 Dec - 26 Dec
Casa Noa Colonial Rooms

Upper House

Upper House
2.5 star property
Cartagena Walled City, 0.5 km from Santo Domingo Square
9.4 out of 10, Exceptional, (48)
"Super nice place :)"
United States
Samuel
The price is AED 378
AED 382 total
14 Dec - 15 Dec
Upper House

Hotel Santa Catalina By OxoHotel

Hotel Santa Catalina By OxoHotel
4.0 star property
Cartagena Centro, 0.3 km from Santo Domingo Square
9.2 out of 10, Wonderful, (1002)
"Location is great and the property very nice. "
United States
Lilian
The price is AED 811
AED 811 total
8 Jan - 9 January 2026
Hotel Santa Catalina By OxoHotel

Terrazas Hotel Boutique

Terrazas Hotel Boutique
5.0 star property
La Matuna, 0.4 km from Santo Domingo Square
9.4 out of 10, Exceptional, (56)
"Small place, but nice"
United States
Jorge
The price is AED 539
AED 539 total
21 Dec - 22 Dec
Terrazas Hotel Boutique
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Santo Domingo Square Hotel Reviews

Hotels near other Santo Domingo Square attractions

Frequently asked questions

What's the area like around Santo Domingo Square?
Santo Domingo Square is located in a historic area of Cartagena known for its beautiful beaches. If you're looking for a convenient place to stay, check out the 1151 hotels and other accommodations you'll find within a mile.
Where is the best place to stay near Santo Domingo Square?
Adjacent to Santo Domingo Square, Hotel Santa Catalina By OxoHotel is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a restaurant. Other good choices within a short distance include Hyatt Regency Cartagena and Osh Hotel Cartagena.
How many hotels can I expect to find close to Santo Domingo Square?
Expedia has 1151 hotels and other accommodations within a mile from Santo Domingo Square.
If I need to cancel the hotel reservation for my stay near Santo Domingo Square, will I receive a refund?
Yes! The majority of room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a non-refundable reservation, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Put your dates in and click on "Search", then use the "fully refundable" filter to review the top deals on offer near Santo Domingo Square.
Where can I learn more about changing or cancelling my trip in the area near Santo Domingo Square?
To access more information about picking new dates or cancelling your stay near Santo Domingo Square, go to https://www.expedia.com/service/.
What can I see and do near Santo Domingo Square?
Study the collections at Palace of the Inquisition Cartagena Historical Museum, Bastion of Santiago, or Palacio de la Inquisicion. Cartagena Cathedral, Plaza Santo Domingo, and San Pedro Claver Church and Convent are monuments to see when you're exploring the area around Santo Domingo Square. You can enjoy live performances at Teatro Heredia and Ciudad Movil Cultural Center.

Explore a world of travel with Expedia