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Sikeston Vacation Rentals

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Check prices for these dates

In two weeks
24 Jul - 26 Jul
In two months
4 Sep - 6 Sep
In three months
2 Oct - 4 Oct
In four months
30 Oct - 1 Nov

Our top choices for Sikeston vacation rentals

Living area

Little Blue Cottage on Spanish

Little Blue Cottage on Spanish
Cape Girardeau
8.4 out of 10, Very Good, (57 reviews)
"Great cute place. "
United States
Jeremy W.
The price is AED 298
AED 397 total
includes taxes & fees
8 Jul - 9 Jul
Little Blue Cottage on Spanish
Outdoor dining

Studio Apt | King Bed, Full Kitchen · By KeenStays

Studio Apt | King Bed, Full Kitchen · By KeenStays
Cape Girardeau
10.0 out of 10, Exceptional, (1 review)
"I loved the location and the staff was wonderful. The bed was comfortable. I loved that King size bed!"
United States
Melvin
The price is AED 294
AED 614 total
includes taxes & fees
8 Jul - 9 Jul
Studio Apt | King Bed, Full Kitchen · By KeenStays
Exterior

Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy

Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy
Dexter
7.8 out of 10, Good, (34 reviews)
"Stayed many times. Nice and comfortable "
United States
Susan R.
The price is AED 393
AED 789 total
includes taxes & fees
12 Jul - 13 Jul
Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy
Exterior

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
Cape Girardeau
8.8 out of 10, Excellent, (41 reviews)
"Will definitely book again! Great location, comfortable stay."
United States
Pynktoria !.
The price is AED 658
AED 1,165 total
includes taxes & fees
14 Jul - 15 Jul
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
TV, offices

Modern Boho Getaway · 1BR Apartment · By KeenStays

Modern Boho Getaway · 1BR Apartment · By KeenStays
Cape Girardeau
The price is AED 294
AED 614 total
includes taxes & fees
2 Aug - 3 Aug
Modern Boho Getaway · 1BR Apartment · By KeenStays
Outdoor dining

A-Frame Cottage with Deck in Charming Inspiration Village

A-Frame Cottage with Deck in Charming Inspiration Village
Cape Girardeau
The price is AED 612
AED 886 total
includes taxes & fees
8 Jul - 9 Jul
A-Frame Cottage with Deck in Charming Inspiration Village
Fridge, microwave, oven, stovetop

Relax in the country at Countryside Villas! - Villa A

Relax in the country at Countryside Villas! - Villa A
Jackson
10.0 out of 10, Exceptional, (36 reviews)
"Great place to stay, felt like home away from home. "
United States
Brittany
The price is AED 551
AED 656 total
includes taxes & fees
6 Aug - 7 Aug
Relax in the country at Countryside Villas! - Villa A
Interior

Villa B offers peace and quiet with beautiful views of the countryside.

Villa B offers peace and quiet with beautiful views of the countryside.
Jackson
10.0 out of 10, Exceptional, (12 reviews)
"It was great. "
United States
Benjamin Q.
The price is AED 551
AED 656 total
includes taxes & fees
6 Aug - 7 Aug
Villa B offers peace and quiet with beautiful views of the countryside.
Terrace/patio

Romantic Tea Cottage Retreat on Boulder Creek with Firepit and Deck

Romantic Tea Cottage Retreat on Boulder Creek with Firepit and Deck
Cape Girardeau
The price is AED 570
AED 834 total
includes taxes & fees
8 Jul - 9 Jul
Romantic Tea Cottage Retreat on Boulder Creek with Firepit and Deck
Property grounds

Vibrant Lofted Tiny Home

Vibrant Lofted Tiny Home
Cape Girardeau
10.0 out of 10, Exceptional, (1 review)
"The tiny house was adorable, clean, and everything we expected. We can’t wait to stay in the others. We definitely recommend staying here. Lisa and Holly have done a wonderful job. Holly was great at getting back to me. Loved everything about our stay and the trip. Thank you so much"
United States
Kim K.
The price is AED 591
AED 860 total
includes taxes & fees
19 Jul - 20 Jul
Vibrant Lofted Tiny Home
TV, fireplace

Gorgeous 1856 Log Cabin, Completely Renovated

Gorgeous 1856 Log Cabin, Completely Renovated
Jackson
10.0 out of 10, Exceptional, (4 reviews)
"This was the coolest place! Our family absolutely loved it. Plenty of space, bathrooms, sitting areas outside were plenty as well as fireplaces and fire pit. The bedrooms are spacious- the area where the two twin beds are is downstairs and the beds are smaller but just know that going in. Beautiful area. We’d love to stay again."
United States
Victoria
The price is AED 735
AED 1,153 total
includes taxes & fees
14 Jul - 15 Jul
Gorgeous 1856 Log Cabin, Completely Renovated
Interior

Charming Secluded Getaway Cabin within minutes of amenities

Charming Secluded Getaway Cabin within minutes of amenities
Cape girardeau
10.0 out of 10, Exceptional, (22 reviews)
"Very peaceful"
United States
Gloria M.
The price is AED 569
AED 1,119 total
includes taxes & fees
8 Jul - 9 Jul
Charming Secluded Getaway Cabin within minutes of amenities
Interior

The Twisted Sassafras Treehouse

The Twisted Sassafras Treehouse
Cape Girardeau
10.0 out of 10, Exceptional, (34 reviews)
"Nice, quiet, close to shopping & restaurants"
United States
Jaime M.
The price is AED 790
AED 1,165 total
includes taxes & fees
8 Jul - 9 Jul
The Twisted Sassafras Treehouse
1 bedroom, desk, iron/ironing board, WiFi

The Cottage, Rusted Route Farms

The Cottage, Rusted Route Farms
Jackson
10.0 out of 10, Exceptional, (2 reviews)
"This Cottage was very nice and clean and well maintained. The meat tray that we ordered and the breakfast tray was beyond Fabulous!!! My husband is still talking about it. . .Rick & Renee Christman"
United States
Renee C.
The price is AED 459
AED 731 total
includes taxes & fees
12 Jul - 13 Jul
The Cottage, Rusted Route Farms
Pool

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
Cape Girardeau
9.6 out of 10, Exceptional, (9 reviews)
"Nice place, great times"
United States
Jace W.
The price is AED 1,240
AED 2,038 total
includes taxes & fees
14 Jul - 15 Jul
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
1 bedroom, free WiFi, bed sheets

Purple Tiny House with Fire pit & Nature

Purple Tiny House with Fire pit & Nature
Cape Girardeau
The price is AED 507
AED 760 total
includes taxes & fees
8 Jul - 9 Jul
Purple Tiny House with Fire pit & Nature
Property grounds

European Inspired Lofted Cottage in Tiny Home Village

European Inspired Lofted Cottage in Tiny Home Village
Cape Girardeau
The price is AED 570
AED 834 total
includes taxes & fees
8 Jul - 9 Jul
European Inspired Lofted Cottage in Tiny Home Village
Smart TV

Rent All 5 Suites at Peach Tree Inn

Rent All 5 Suites at Peach Tree Inn
Cobden
The price is AED 2,775
AED 3,405 total
includes taxes & fees
8 Jul - 9 Jul
Rent All 5 Suites at Peach Tree Inn
Interior

The Atrium - A Boutique Hotel

The Atrium - A Boutique Hotel
2.0 star property
Perryville
9.6 out of 10, Exceptional, (4 reviews)
"What an amazing little suite wrapped in a very thought-filled overall venue. Very unique room with a so many details. The overall building with fire pit, game rooms, and local vendor items…all was quite amazing. Every element is thought out very well. It is very convenient and overall comfortable. It was a great getaway."
United States
Brian
The price is AED 252
AED 555 total
includes taxes & fees
2 Aug - 3 Aug
The Atrium - A Boutique Hotel
Interior

Cozy and Updated Farmhouse with King Suite

Cozy and Updated Farmhouse with King Suite
Anna
9.8 out of 10, Exceptional, (20 reviews)
"Nice little house that was perfect for our family of five plus our dog. We would stay here again if we found ourselves out this way again."
United States
Kyle
The price is AED 327
AED 580 total
includes taxes & fees
13 Jul - 14 Jul
Cozy and Updated Farmhouse with King Suite
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Sikeston Hotel Reviews

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

8/10 Good
"Can’t wait to come back"
Kimesha 3-night trip
Posted less than an hour ago
Drury Plaza Hotel Cape Girardeau Conference Center

Frequently asked questions

Can I find a vacation rental in Sikeston?

Yes, there are vacation rentals close to the most popular local attractions in Sikeston, or you can choose a more remote option if you're looking for relaxation. Tourists like the array of shops and top-notch restaurants in Sikeston. Make sure you allow time to enjoy the riverfront during your vacation.

What's the top vacation rental in Sikeston?

Beautiful location in the secluded woods : Visitors like this Sikeston vacation home rental. It offers a fireplace, a patio, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Make the most of the selection of games in this rental home to help you unwind.

What’s there to see and do in Sikeston?

Cultural attractions include Sikeston Depot Museum, whereas Central Park is a spot to enjoy nature. In the larger area, you’ll find Front Street Studio & Art Gallery and Stoddard County Civil War Memorial Cemetery.

What’s a vacation rental in Sikeston like?

A vacation rental is a private property you can book for a couple of days or more in Sikeston. Vacation rentals feature extras such as kitchens and laundry facilities so you'll feel right at home. If you're concerned about a clean environment, a vacation rental can offer a sense of security away from public hotel elevators and busy reception areas while still allowing you to travel. You'll also get more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a popular option for a small group gathering.