Find Resorts & Hotels with Spas in Simpsonville, SC

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Check availability on Simpsonville Resorts & Hotels with Spas

Our top choices for Simpsonville hotels with a spa

Couples treatment rooms, body treatments, body wraps, body scrubs
Hotel Hartness

Hotel Hartness

Hotel Hartness
4.0 star property
Greenville
9.8 out of 10, Exceptional, (624)
"Beautiful location, friendly staff"
United States
Andrew
The price is AED 556
AED 735 total
includes taxes & fees
15 Dec - 16 Dec
Hotel Hartness
Spa
Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection
4.0 star property
Greenville Downtown
9.6 out of 10, Exceptional, (418)
"Absolutely one of the best hotels to stay at. "
United States
stephen
The price is AED 1,054
AED 1,191 total
includes taxes & fees
4 Jan - 5 January 2026
Grand Bohemian Lodge Greenville, Autograph Collection
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Simpsonville Hotel Reviews

Drury Inn & Suites Greenville

Drury Inn & Suites Greenville

10/10 Excellent
"Very nice amenities and rooms. Staff was super friendly and very helpful when needed. We will definitely stay at another Drury Inn when traveling or needing a hotel"
Blair 2-night trip
Posted 3 days ago
Drury Inn & Suites Greenville

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Frequently asked questions

Looking to vacation at a spa hotel in Simpsonville?
Forget the stress of everyday life and book yourself a hotel with a spa. Check out the live music scene and historical sites in Simpsonville—your cultural tour starts here. Hotels with spas are the perfect way to break away from your routine and add a layer of luxury to your holiday.
What's there to see and do in Simpsonville?
Take in the sights and attractions that Simpsonville offers with a visit to Heritage Park, Regal Simpsonville, and Beck Plaza. If you have spare time during your trip, you might want to make a stop at Bradford Plaza and The Market at Standing Springs.
What is a Simpsonville spa hotel?
Spa hotels in Simpsonville provide lodging and have an on-site spa which offers services such as massages as well as beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.