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Check availability on Southeast Minnesota Historic Hotels

Our top choices for Southeast Minnesota historic hotels

A Comfort Inn & Suites hotel with a modern design, featuring a prominent signage and a parking lot.

1. Comfort Inn & Suites Rochester South Mayo Clinic

Comfort Inn & Suites Rochester South Mayo Clinic
2.0 star property
Rochester
8.8 out of 10, Excellent, (1,000 reviews)
"Great place to stay."
United States
LeeAnn
The price is AED 244
AED 281 total
includes taxes & fees
12 Dec - 13 Dec
Comfort Inn & Suites Rochester South Mayo Clinic
A hotel kitchen with a long counter, coffee machines, a bread display, and a fruit bowl.

2. Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area
2.0 star property
Rochester
9.0 out of 10, Wonderful, (1,000 reviews)
"Clean room and breakfast area was very clean."
United States
Britta
The price is AED 247
AED 284 total
includes taxes & fees
12 Dec - 13 Dec
Econo Lodge Mayo Clinic Area
A modern hotel lobby with a reception desk, seating area, and a large window providing natural light.

3. Spark by Hilton Rochester South

Spark by Hilton Rochester South
3.0 star property
Rochester
9.2 out of 10, Wonderful, (610 reviews)
"Great value"
United States
Jen
The price is AED 278
AED 320 total
includes taxes & fees
28 Nov - 29 Nov
Spark by Hilton Rochester South
A modern dining area with high tables, chairs, and pendant lighting.

4. Hampton Inn & Suites Rochester-North

Hampton Inn & Suites Rochester-North
2.5 star property
Rochester
9.2 out of 10, Wonderful, (1,000 reviews)
"Clean room great facilities."
United States
Mark
The price is AED 358
AED 413 total
includes taxes & fees
28 Nov - 29 Nov
Hampton Inn & Suites Rochester-North
An outdoor seating area with a fire feature, blue cushioned chairs, and a modern building with large windows in the background.

5. Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area
3.0 star property
Downtown Rochester
9.0 out of 10, Wonderful, (1,002 reviews)
"Great stay."
Canada
Robert Blaise
The price is AED 408
AED 470 total
includes taxes & fees
27 Nov - 28 Nov
Hyatt House Rochester/Mayo Clinic Area
A modern outdoor seating area with a built-in fireplace, two wooden chairs, a table, and a sofa.

6. EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG
4.0 star property
Kutzky Park
9.4 out of 10, Exceptional, (1,001 reviews)
"Very nice, well kept, comfy beds, nice staff"
United States
Ashley
The price is AED 419
AED 532 total
includes taxes & fees
26 Nov - 27 Nov
EVEN Hotel Rochester - Mayo Clinic Area by IHG
A modern living room with a stone fireplace, a blue armchair, a round coffee table, and a large window offering a view of the outdoors.

7. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
3.0 star property
Kutzky Park
9.6 out of 10, Exceptional, (755 reviews)
"The staff was extremely helpful making for a comfortable stay."
United States
Brien
The price is AED 410
AED 472 total
includes taxes & fees
22 Nov - 23 Nov
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
An outdoor seating area with colorful striped sofas and yellow chairs, a fire pit, and a covered patio with string lights.

8. Home2 Suites by Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area
3.0 star property
Rochester
9.4 out of 10, Exceptional, (1,001 reviews)
"Clean room, very nice staff and nice atmosphere."
United States
howard
The price is AED 403
AED 464 total
includes taxes & fees
13 Dec - 14 Dec
Home2 Suites by Hilton Rochester Mayo Clinic Area
A restaurant with wooden tables and bar stools, a bar area with a counter, and multiple televisions mounted on the walls.

9. AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic
3.0 star property
Rochester
8.2 out of 10, Very good, (1,596 reviews)
"Great stay, we were only there for one night, but the staff was very nice and helpful!"
United States
Madelyn
The price is AED 268
AED 309 total
includes taxes & fees
6 Dec - 7 Dec
AmericInn by Wyndham Rochester Near Mayo Clinic
A Sleep Inn hotel with a covered entrance, stone pillars, and a clear blue sky.

10. Sleep Inn & Suites West-Near Medical Center

Sleep Inn & Suites West-Near Medical Center
2.5 star property
Rochester
9.0 out of 10, Wonderful, (729 reviews)
"Just a pleasant hotel a few hours from NYC"
United States
Christopher
The price is AED 269
AED 310 total
includes taxes & fees
11 Dec - 12 Dec
Sleep Inn & Suites West-Near Medical Center
An outdoor patio area with wicker furniture, a central fire feature, and a stone building in the background.

11. Residence Inn by Marriott Rochester Mayo Clinic Area South

Residence Inn by Marriott Rochester Mayo Clinic Area South
3.0 star property
Rochester
9.6 out of 10, Exceptional, (321 reviews)
"Clean hotel, friendly staff, great location."
United States
Chee
The price is AED 485
AED 558 total
includes taxes & fees
27 Nov - 28 Nov
Residence Inn by Marriott Rochester Mayo Clinic Area South
A Holiday Inn Express building with a covered entrance, multiple floors, and a parking lot.

12. Holiday Inn Express Rochester South - Mayo Area by IHG

Holiday Inn Express Rochester South - Mayo Area by IHG
2.5 star property
Rochester
8.8 out of 10, Excellent, (1,001 reviews)
"Nice location, easy access and good breakfast."
United States
Rick
The price is AED 294
AED 338 total
includes taxes & fees
11 Dec - 12 Dec
Holiday Inn Express Rochester South - Mayo Area by IHG
A coffee shop interior with a wooden counter, menu boards, and seating area.

13. TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area
3.0 star property
Kutzky Park
9.6 out of 10, Exceptional, (577 reviews)
"This location is awesome if you are going to Mayo Clinic. What an easy walk to the clinic. Several great restaurants are also within walking distance."
United States
Neil
The price is AED 503
AED 579 total
includes taxes & fees
27 Nov - 28 Nov
TownePlace Suites by Marriott Rochester Mayo Clinic Area
A reception area with a wooden reception desk, a "Welcome to the Bread & Butter State" sign, and a "Please Center" sign.

14. Hampton Inn Rochester-South

Hampton Inn Rochester-South
2.5 star property
Rochester
9.0 out of 10, Wonderful, (1,001 reviews)
"Great stay"
United States
Susan
The price is AED 356
AED 410 total
includes taxes & fees
12 Dec - 13 Dec
Hampton Inn Rochester-South
A modern living room with a sofa, coffee table, and a TV mounted on a stone wall.

15. Quality Inn & Suites Mayo Clinic Area

Quality Inn & Suites Mayo Clinic Area
2.5 star property
Rochester
8.8 out of 10, Excellent, (973 reviews)
"Nice location, staff very helpful and friendly, and nice big room"
United States
Mark
The price is AED 247
AED 288 total
includes taxes & fees
11 Dec - 12 Dec
Quality Inn & Suites Mayo Clinic Area
An outdoor seating area with stone walls, a fire pit, and wicker chairs.

16. Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
3.0 star property
Kutzky Park
9.2 out of 10, Wonderful, (542 reviews)
"Clean, spacious and very modern. Would definitely stay here again."
United States
Paul
The price is AED 403
AED 464 total
includes taxes & fees
25 Nov - 26 Nov
Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
A modern living room with a flat-screen TV, a fireplace, a sofa, a coffee table, and a view of a cityscape through large windows.

17. Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area
3.5 star property
Downtown Rochester
9.6 out of 10, Exceptional, (657 reviews)
"Clean rooms, great staff, convenient location."
United States
Jennifer
The price is AED 621
AED 715 total
includes taxes & fees
27 Nov - 28 Nov
Hilton Rochester Mayo Clinic Area
A Comfort Inn hotel with a stone facade, a covered entrance, and a parking area.

18. Comfort Inn & Suites West - Medical Center

Comfort Inn & Suites West - Medical Center
3.0 star property
Rochester
8.8 out of 10, Excellent, (670 reviews)
"Great stay"
United States
Angela
The price is AED 302
AED 348 total
includes taxes & fees
11 Dec - 12 Dec
Comfort Inn & Suites West - Medical Center
A modern living room with a fireplace, comfortable seating, and large windows.

19. Staybridge Suites Rochester - Mayo Clinic Area by IHG

Staybridge Suites Rochester - Mayo Clinic Area by IHG
3.0 star property
Kutzky Park
9.4 out of 10, Exceptional, (564 reviews)
"Love this place!"
United States
Sheri
The price is AED 386
AED 451 total
includes taxes & fees
25 Nov - 26 Nov
Staybridge Suites Rochester - Mayo Clinic Area by IHG
A garden with a water feature, rocks, and yellow umbrellas.

20. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
3.0 star property
Historic Southwest
8.6 out of 10, Excellent, (1,002 reviews)
"Great place to stay"
United States
Jordan
The price is AED 419
AED 483 total
includes taxes & fees
14 Nov - 15 Nov
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Southeast Minnesota Hotel Reviews

Super 8 by Wyndham Winona MN

Super 8 by Wyndham Winona MN

8/10 Good
"cleanliness"
Chueyee 1-night trip
Posted 2 hours ago
Super 8 by Wyndham Winona MN

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