Find all hotels by Motel 6 in Southeast Missouri, MO from AED 264
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check prices for these dates
Tonight
18 Aug - 19 AugTomorrow
19 Aug - 20 AugThis weekend
21 Aug - 23 AugNext weekend
28 Aug - 30 AugOur top choices for Southeast Missouri Motel 6
AED 290
AED 325 total
includes taxes & fees
19 Aug - 20 Aug
AED 224
AED 264 total
includes taxes & fees
16 Sep - 17 Sep
Save an average of 15% on thousands of hotels when you're signed in
Top Southeast Missouri Hotel Reviews
Comfort Inn Festus - St Louis South
10/10 Excellent
"Clean room and relaxing 1-night stay"
Drury Inn & Suites Sikeston, MO
10/10 Excellent
"Food was good, beautiful and functional lobby, nice friendly staff, room clean. Couldn’t ask for more."
Motel 6 Poplar Bluff, MO
8/10 Good
"Clean and nice."
Drury Plaza Hotel Cape Girardeau Conference Center
10/10 Excellent
"The breakfast was great."
Baymont Inn and Suites by Wyndham Farmington, MO
10/10 Excellent
"The staff were very helpful. The room was in good shape."
Candlewood Suites Cape Girardeau by IHG
10/10 Excellent
"Property was clean a room was stocked. Had microwave refrigerator and a stove refrigerator had working ice maker. Great room for the price"
Fairfield Inn & Suites by Marriott Poplar Bluff
10/10 Excellent
"Clean room help staff basic breakfast, but was good parking. Plenty easy to reach."
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
10/10 Excellent
"It was a very unique and great experience! Would definitely recommend to others."
Silo Farm Haus- located in the heart of wine country!
10/10 Excellent
"Our stay at the Silo House was absolutely wonderful! The home and surrounding property are stunning, and the peaceful setting made it the perfect escape from the hustle and bustle of everyday life. If you’re looking for a place to truly relax and recharge, this is it.My favorite part of the entire stay was starting each morning on the porch swing, watching the sunrise while listening to the sounds of nature. It was such a calming and memorable experience.The house itself was immaculate and thoughtfully equipped with every amenity you could possibly need. It was clear that every detail had been considered to make guests feel comfortable and at home.We couldn’t have asked for a better getaway and would absolutely stay here again. Highly recommend the Silo House to anyone looking for a peaceful, beautiful retreat!"
Explore a world of travel with Expedia
- 4 Star Hotels in Doe Run
- Middle Brook Hotels
- 5 Star Hotels in Piedmont
- Best Western Hotels in Potosi
- Resorts & Hotels with Spas in Farmington
- La Quinta Inn & Suites Hotels in Southeast Missouri
- Cottages in Doe Run
- Cabin Rentals in Southeast Missouri
- Vacation Homes in Sturdivant
- Vacation Homes in Piedmont
- Hotels with Bars in Farmington
- 5 Star Hotels in Middle Brook
- Premier Inn Hotels in Park Hills
- Independent Hotels in Friedheim
- Golf Hotels in Southeast Missouri
- Wyndham Hotels in Bonne Terre
- Farmington Hotels
- Hotels with Hot Tubs in Southeast Missouri
- Vacation Homes in Southeast Missouri
- Marriott Hotels & Resorts in Farmington
- Best Western Hotels in Bloomfield
- Wyndham Hotels in Park Hills
- Motels in Ironton
- 2 Star Hotels in Pilot Knob
- Cabin Rentals in Farmington
- Wyndham Hotels in Fredericktown
- Independent Hotels in Marble Hill
- Drury Inn & Suites Hotels in Perryville
- Wyndham Hotels in Sedgewickville
- Wyndham Hotels in St Mary
- Cabin Rentals in Park Hills
- 4 Star Hotels in Piedmont
- 2 Star Hotels in Black
- Hilton Hotels in Valles Mines
- Hilton Hotels in Potosi
- 2 Star Hotels in Lesterville
- Vacation Homes in Leadwood
- Wyndham Hotels in Doe Run
- Apartments in Piedmont
- Pilot Knob Hotels
- Motels in Doe Run
- 5 Star Hotels in Arcadia
- 2 Star Hotels in Lowndes
- 2 Star Hotels in Park Hills
- 2 Star Hotels in Fredericktown
- Hilton Hotels in Poplar Bluff
- Rv Parks in Southeast Missouri
- Pet-Friendly Hotels in Southeast Missouri
- Winery Hotels in Southeast Missouri
- Motels in Fredericktown
- Hotels near Fort Davidson State Historic Site
- Independent Hotels in Bonne Terre
- Wyndham Hotels in Friedheim
- 4 Star Hotels in Leadwood
- Hotels with WiFi in Pilot Knob
- Cabin Rentals in Belleview
- Cottages in Caledonia
- Cottages in Ironton
- Wyndham Hotels in Bloomfield
- Aimbridge Hospitality Hotels in Wappapello
- Independent Hotels in Poplar Bluff
- Farmstay in Ellington
- Accor Hotels in Potosi
- Hotels near Twin Oaks Vineyard & Winery
- 5 Star Hotels in Ironton
- 4 Star Hotels in Fredericktown
- 5 Star Hotels in Flat River
- Motels in Ellington
- Farmstay in Sedgewickville
- Hilton Hotels in Arcadia
- 3 Star Hotels in Pilot Knob
- Independent Hotels in Cadet
- Drury Inn & Suites Hotels in Jackson
- 2 Star Hotels in Piedmont
- Motels in Park Hills
- Apartments in Lesterville
- Hilton Hotels in Belleview
- Red Carpet Inn Hotels in Bloomfield
- B&B in Ironton
- Hotels near Bollinger Mill State Historic Site
- Wyndham Hotels in Caledonia
- Wyndham Hotels in Pilot Knob
- 2 Star Hotels in Sturdivant
- 4 Star Hotels in Ellington
- Hotels with Free Parking in Farmington
- Flights from Park Hills
- Flights from Pilot Knob
- Flights from Lowndes
- Flights from Flat River
- Flights from Ellington
- Flights from Ironton
- Flights from Fredericktown
- Flights from Leadwood
- Flights from Farmington
- Flights from Desloge
- Flights to Black
- Flights from Caledonia
- Flights from Annapolis
- Flights from Lesterville