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9 Dec - 10 Dec
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10 Dec - 11 Dec
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12 Dec - 14 Dec
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19 Dec - 21 Dec

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Our top choices for Southern Illinois Healthcare hotels

Terrace/patio
Home2 Suites by Hilton Carbondale

Home2 Suites by Hilton Carbondale

3.0 star property
2.8 km from Southern Illinois Healthcare
8.8 out of 10, Excellent, (510)
"Great location. Nice, new hotel. Spacious room."
United States
Sabrina
The price is AED 408
AED 470 total
includes taxes & fees
4 Jan - 5 January 2026
Home2 Suites by Hilton Carbondale
Exterior
Holiday Inn Carbondale-Conference Center by IHG

Holiday Inn Carbondale-Conference Center by IHG

3.0 star property
2.5 km from Southern Illinois Healthcare
8.8 out of 10, Excellent, (640)
"Great staff!"
United States
Greg
The price is AED 393
AED 452 total
includes taxes & fees
21 Dec - 22 Dec
Holiday Inn Carbondale-Conference Center by IHG
Standard Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave (Pet Friendly) | Desk, blackout drapes, iron/ironing board, free WiFi
Best Western Saluki Inn

Best Western Saluki Inn

2.5 star property
0.2 km from Southern Illinois Healthcare
8.0 out of 10, Very Good, (1004)
"It was fine for the price and location. Good value if all you need is a no frills hotel room, and much better since the re-model. Clean room and staff was friendly and courteous. Easy walk to Buffalo Wild Wings and Fujiyama Japanese Steak House and a few others. Would stay there again."
United States
Douglas
The price is AED 290
AED 341 total
includes taxes & fees
22 Dec - 23 Dec
Best Western Saluki Inn
Front of property - evening/night
Hampton Inn Carbondale

Hampton Inn Carbondale

2.5 star property
2.1 km from Southern Illinois Healthcare
8.4 out of 10, Very Good, (611)
"Room was spotless, check in was quick, all personnel were courteous. "
United States
William
The price is AED 408
AED 470 total
includes taxes & fees
17 Dec - 18 Dec
Hampton Inn Carbondale
Studio Suite, 1 King Bed, Non Smoking | Desk, laptop workspace, iron/ironing board, rollaway beds
Super 8 by Wyndham Carbondale

Super 8 by Wyndham Carbondale

2.0 star property
0.8 km from Southern Illinois Healthcare
7.4 out of 10, Good, (1001)
"Room was clean but a bit dated. "
United States
Giovanni
The price is AED 202
AED 232 total
includes taxes & fees
10 Dec - 11 Dec
Super 8 by Wyndham Carbondale
Lobby
Comfort Inn & Suites Carbondale University Area

Comfort Inn & Suites Carbondale University Area

2.5 star property
2.6 km from Southern Illinois Healthcare
7.6 out of 10, Good, (515)
"Our room was clean and our stay was comfortable. We were not expecting a 5 star hotel due to the price and felt we received a good value for what we paid. We would stay again."
United States
James
The price is AED 275
AED 316 total
includes taxes & fees
23 Dec - 24 Dec
Comfort Inn & Suites Carbondale University Area
Exterior
Quality Inn Carbondale University area

Quality Inn Carbondale University area

2.5 star property
0.3 km from Southern Illinois Healthcare
5.8 out of 10, (835)
"This was a good place to stay"
United States
Ronald
The price is AED 199
AED 228 total
includes taxes & fees
7 Jan - 8 January 2026
Quality Inn Carbondale University area
Indoor pool, seasonal outdoor pool
Walker's Bluff Casino Resort

Walker's Bluff Casino Resort

4.5 star property
8.3 km from Southern Illinois Healthcare
9.4 out of 10, Exceptional, (386)
"Great place!!"
United States
Jeff
Walker's Bluff Casino Resort
Free daily self-serve breakfast
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

2.5 star property
12.6 km from Southern Illinois Healthcare
9.4 out of 10, Exceptional, (510)
"great property, great breakfast, friendly and knowledgable staff."
United States
Ronald
The price is AED 393
AED 436 total
includes taxes & fees
21 Dec - 22 Dec
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
Lobby
Comfort Inn & Suites Marion I-57

Comfort Inn & Suites Marion I-57

2.5 star property
19.3 km from Southern Illinois Healthcare
9.4 out of 10, Exceptional, (1001)
"Very clean room, friendly staff, and the breakfast was tasty. Will stay there again"
United States
Marcus
The price is AED 397
AED 476 total
includes taxes & fees
5 Jan - 6 January 2026
Comfort Inn & Suites Marion I-57
Exterior
Drury Inn & Suites Marion

Drury Inn & Suites Marion

3.0 star property
19.4 km from Southern Illinois Healthcare
9.4 out of 10, Exceptional, (1002)
"Great hotel and very clean "
United States
Jose
The price is AED 239
AED 286 total
includes taxes & fees
2 Jan - 3 January 2026
Drury Inn & Suites Marion
Lobby
Country Inn & Suites by Radisson, Marion, IL

Country Inn & Suites by Radisson, Marion, IL

2.5 star property
19.5 km from Southern Illinois Healthcare
8.6 out of 10, Excellent, (1003)
"Room was nice and staff was friendly."
United States
MING
The price is AED 356
AED 427 total
includes taxes & fees
29 Dec - 30 Dec
Country Inn & Suites by Radisson, Marion, IL
Free daily continental breakfast
Fairfield Inn and Suites by Marriott Marion

Fairfield Inn and Suites by Marriott Marion

2.5 star property
19.6 km from Southern Illinois Healthcare
8.4 out of 10, Very Good, (358)
"The room was clean and comfortable bed"
United States
Marilee
The price is AED 323
AED 388 total
includes taxes & fees
28 Dec - 29 Dec
Fairfield Inn and Suites by Marriott Marion
Lobby sitting area
Baymont by Wyndham Marion

Baymont by Wyndham Marion

2.5 star property
19.7 km from Southern Illinois Healthcare
8.4 out of 10, Very Good, (1066)
"This place was nice for the money and our 1 night stay. "
United States
Charles
The price is AED 276
AED 331 total
includes taxes & fees
1 Jan - 2 January 2026
Baymont by Wyndham Marion
Desk, iron/ironing board, free cribs/infant beds, free rollaway beds
Super 8 by Wyndham Marion

Super 8 by Wyndham Marion

2.0 star property
19.7 km from Southern Illinois Healthcare
7.6 out of 10, Good, (1002)
"Decent room for the cost compared to others."
United States
Nicole
The price is AED 272
AED 326 total
includes taxes & fees
15 Dec - 16 Dec
Super 8 by Wyndham Marion
Lobby
Motel 6 Marion, IL

Motel 6 Marion, IL

2.0 star property
15.7 km from Southern Illinois Healthcare
7.2 out of 10, Good, (607)
"This is a no frills motel that offers great value for the money! I found it to be safe, quiet and convenient to dining, shopping and several nearby towns. Would not hesitate to stay here again! The owner and staff work hard to ensure a pleasant stay!"
United States
Charles
The price is AED 220
AED 245 total
includes taxes & fees
16 Dec - 17 Dec
Motel 6 Marion, IL
Lobby
Quality Inn And Suites

Quality Inn And Suites

2.5 star property
19.8 km from Southern Illinois Healthcare
7.4 out of 10, Good, (1003)
"Clean room. Friendly staff. My 2nd stay here. Good room for the price. Would stay here again. "
United States
Rodney
The price is AED 215
AED 258 total
includes taxes & fees
7 Jan - 8 January 2026
Quality Inn And Suites
Front of property
University Inn of Carbondale

University Inn of Carbondale

2.5 star property
5.3 km from Southern Illinois Healthcare
6.0 out of 10, (325)
"Yes everything was great"
United States
Jesse
University Inn of Carbondale
Free daily buffet breakfast
Holiday Inn Express Hotel & Suites Marion Northeast by IHG

Holiday Inn Express Hotel & Suites Marion Northeast by IHG

2.5 star property
19.8 km from Southern Illinois Healthcare
9.0 out of 10, Wonderful, (925)
"yes the room was great and the staff was great! "
United States
Amador
The price is AED 356
AED 427 total
includes taxes & fees
9 Jan - 10 January 2026
Holiday Inn Express Hotel & Suites Marion Northeast by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Southern Illinois Healthcare Hotel Reviews

Best Western Saluki Inn

Best Western Saluki Inn

10/10 Excellent
"Yes, very clean"
Nancy 1-night trip
Posted 2 days ago
Best Western Saluki Inn

Hotels near other Southern Illinois Healthcare attractions

African American Museum of Southern Illinois

You can spend time exploring the galleries in African American Museum of Southern Illinois in Carbondale. Check out the shops and top-notch restaurants in this family-friendly area.
See properties

The Science Center

You can take time to visit The Science Center during your travels to Carbondale. Check out the shops and top-notch restaurants in this family-friendly area.
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Frequently asked questions

What's the area like around Southern Illinois Healthcare?
Southern Illinois Healthcare is located in Carbondale. This family-friendly area is known for its array of dining options and major shopping area. You'll find 63 hotels and other accommodations within a few miles for a convenient home base.
What's the best place to stay close to Southern Illinois Healthcare?
Adjacent to Southern Illinois Healthcare, Best Western Saluki Inn is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. Other good options close by include Super 8 by Wyndham Carbondale and Quality Inn Carbondale University area.
How many hotels can I expect to find close to Southern Illinois Healthcare?
Expedia has 63 hotels and other accommodations a few miles from Southern Illinois Healthcare.
If I need to cancel the hotel reservation for my stay near Southern Illinois Healthcare, will I receive a refund?
Yes! The majority of room reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to get top deals close to Southern Illinois Healthcare.
Where can I learn more about changing or cancelling my trip in the area near Southern Illinois Healthcare?
To find more details about updating your stay near Southern Illinois Healthcare or cancelling it, head over to our customer service page.

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