Ancient stone columns with intricate capitals, surrounded by a chain-link fence, set against a backdrop of lush greenery and a cloudy sky.

Find Resorts & Hotels with Spas in Southwest, MS

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Southwest Resorts & Hotels with Spas

Tonight
11 Oct - 12 Oct
Tomorrow
12 Oct - 13 Oct
Next weekend
16 Oct - 18 Oct
In two weeks
23 Oct - 25 Oct

Our top choices for Southwest hotels with a spa

A hotel room with a large bed, a sitting area with a chair, a desk, a television, a ceiling fan, and a bathtub.
A hotel lobby with a reception desk, dining area with chairs and tables, and a patterned carpet.
A room with a patterned sofa set, a glass coffee table, and a ceiling fan.
A gym with exercise equipment, a clock, and a window.

1. Quality Inn & Suites Clinton - Jackson West

Quality Inn & Suites Clinton - Jackson West
Clinton
  • Soothe your senses at a serene oasis where daily spa treatments and a rejuvenating hot tub create the perfect escape for wellness seekers.
AED 198
AED 218 total
includes taxes & fees
2 Nov - 3 Nov
Quality Inn & Suites Clinton - Jackson West
A living room with a chandelier, two sofas, a coffee table, and a fireplace.
A two-story building with a central entrance, columns, and a balcony with railings.
A covered porch with outdoor seating, a view of the landscape, and a railing.
A stone fountain with water spouting into a pool, surrounded by brick walls and greenery.

2. The Inn at Cedar Grove

The Inn at Cedar Grove
Vicksburg
  • Rejuvenate with deep-tissue massages at this historic inn with a serene garden and seasonal outdoor pool near Vicksburg's attractions.
AED 511
AED 563 total
includes taxes & fees
8 Nov - 9 Nov
The Inn at Cedar Grove
A room with two beds, a chair, a coat rack, and a mirror.
A porch with a bench, potted plants, and an American flag.
A two-story Victorian-style house with a wrap-around porch, a balcony, and a well-maintained front yard.
A house with a porch, surrounded by a garden with various flowers.

3. Devereaux Shields House

Devereaux Shields House
Natchez
  • Rejuvenate with hot stone massages in an elegant bed & breakfast featuring couples treatment rooms and a peaceful garden retreat.
AED 639
AED 714 total
includes taxes & fees
13 Oct - 14 Oct
Devereaux Shields House
A reception desk with a dark, textured surface and decorative leaf patterns. It features multiple shelves with various items and a central vase with flowers.
A modern hotel entrance with a covered walkway, large windows, and a well-lit facade.
Two people walking in a hallway with a modern interior design, including a wooden frame and a wall with black and white photographs.
An outdoor dining area with wicker furniture and red umbrellas, overlooking a modern building with the name "WESTIN" on the facade.

4. The Westin Jackson

The Westin Jackson
Downtown Jackson
  • Immerse in a luxurious wellness retreat with 7 serene treatment rooms at Soul Spa, complemented by an indoor pool and exceptional dining.
AED 496
AED 633 total
includes taxes & fees
18 Oct - 19 Oct
The Westin Jackson
A bedroom with a four-poster bed, a fireplace, and a large painting on the wall.
A dining area with a chandelier, wooden chairs, and a glass table.
A bathroom with a sink, mirror, and shower.
A library with outdoor seating and a large tree in the center.

5. Fairview Inn

Fairview Inn
Greater Belhaven
  • Retreat to a colonial haven with daily full-service spa treatments and serene garden settings at this charming inn.
AED 841
AED 936 total
includes taxes & fees
13 Oct - 14 Oct
Fairview Inn
View all properties

Choose what matters most at spa hotels in Southwest

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Southwest Hotel Reviews

Hilton Garden Inn Jackson/Madison

Hilton Garden Inn Jackson/Madison

10/10 Excellent
"Amazing staff"
Sharon 2-night trip
Posted 1 hour ago
Hilton Garden Inn Jackson/Madison
Baymont by Wyndham Jackson/Ridgeland

Baymont by Wyndham Jackson/Ridgeland

10/10 Excellent
"Nice place to stay"
Jeannie 1-night trip
Posted 1 day ago
Baymont by Wyndham Jackson/Ridgeland
Ameristar Casino Hotel Vicksburg

Ameristar Casino Hotel Vicksburg

10/10 Excellent
"Everyone was nice"
David 4-night trip
Posted 2 days ago
Ameristar Casino Hotel Vicksburg

Explore a world of travel with Expedia