St. Charles County Vacations

Book a Hotel + Flight together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to AED 148 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Top destinations in St. Charles County

St. Charles County Hotel Deals

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
1 Ameristar Blvd St. Charles MO
Fully refundableReserve now, pay when you stay
The price is AED 724 per night from Feb 12 to Feb 13
AED 724
AED 907 total
12 Feb - 13 Feb
includes taxes & fees
8.4/10 Very Good! (1,000 reviews)
The room was great. I enjoyed my stay.

Reviewed on 3 February 2026

Ameristar Casino Resort and Spa
Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

2.5 out of 5
1190 S Main St St. Charles MO
Fully refundable
The price is AED 410 per night from Feb 15 to Feb 16
AED 410
AED 471 total
15 Feb - 16 Feb
includes taxes & fees
9.4/10 Exceptional! (1,000 reviews)
From check in my time at Country Inn was wonderful! The people are so very kind and helpful, the building is spotless, location is perfect and I had everything I needed. I recommend the Country Inn & Suites!

Reviewed on 3 February 2026

Country Inn & Suites by Radisson, St. Charles Historic District
Drury Plaza Hotel St. Louis St. Charles

Drury Plaza Hotel St. Louis St. Charles

3 out of 5
380 Mulholland Drive St. Charles MO
Fully refundableReserve now, pay when you stay
The price is AED 485 per night from Feb 15 to Feb 16
AED 485
AED 562 total
15 Feb - 16 Feb
includes taxes & fees
9.6/10 Exceptional! (1,001 reviews)
Location

Reviewed on 4 February 2026

Drury Plaza Hotel St. Louis St. Charles
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.