Top Vacation Homes in Stoddard County in 2026

A river surrounded by trees and fallen leaves.

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Our top choices for Stoddard County vacation homes

A dining area with a round wooden table, white chairs, a vase with flowers, and a view through large windows.

1. “Kozy on Kingsway” is a charming 4-bedroom house in Cape -The City of Roses

Cape Girardeau

Merry J.

A modern kitchen with stainless steel appliances, wooden cabinets, and a white countertop.

2. The Cutie Patootie on Helen- Cute, Cozy, Comfortable - 3 BR Home in Dexter, MO

Dexter

Robert G.

AED 602 total

includes taxes & fees

10 Nov - 11 Nov

A two-story house with a covered porch, a large window, and a chimney.

3. “Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau

Cape Girardeau

Eric P.

A modern house with a prominent entrance, large windows, and a sloped roof.

4. Urban 2-bedroom Escape in Downtown Cape Girardeau

Cape Girardeau

Connor c.

A hallway with wooden flooring leading to a dining area with a table and chairs.

5. 3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau

Cape Girardeau

Daniel W.

A living room with a TV, a fireplace, a sofa, and wall art.

6. Little Blue Cottage on Spanish

Cape Girardeau

Jeremy W.

AED 368 total

includes taxes & fees

10 Nov - 11 Nov

A hallway with a wooden floor, a chandelier, a door with frosted glass panels, and a small table with a plant.

7. Charming, historic Fuerth House in Downtown Cape Girardeau, 2 bedrooms, 1 bath.

Cape Girardeau

Pam A.

A covered deck with a sofa and table, a wooden ceiling, and a view of a green landscape.

8. Cozy 3-bedroom in Wappapello with AC, WiFi and close to the Lake.

Wappapello

Lori W.

A modern kitchen with a large island, bar stools, and a view of the outdoors.

9. Private lake, beach & hot tub, romantic getaway or family vaca

Wappapello

Bobbie M.

A hot tub in a forested area with a wooden deck and a view of the surrounding trees.

10. Camp Stonebass-Lake House-Hottub

Wappapello

bryan b.

A kitchen with wooden cabinets, a stainless steel refrigerator, a stove, and a window.

11. Hunting / Fishing Cabin at Lake Wappapello

Williamsville

Donna M.

AED 869 total

includes taxes & fees

10 Nov - 11 Nov

A living room with a sofa, armchair, coffee table, and a TV mounted on the wall.

12. Quaint, Beautiful Home next to SEMO and Hospital

Cape Girardeau

Michelle C.

A cozy living room with two leather sofas, a stone wall, wooden ceiling, and a large sliding glass door leading to an outdoor deck.

13. Doc's Cottage - A-Frame in Piggott, AR

Piggott

Mary C.

AED 822 total

includes taxes & fees

10 Nov - 11 Nov

A spacious living area with a dark grey sofa set, a matching ottoman, and a wooden-paneled wall.

14. 40-Acre Poplar Bluff Nature Lovers Paradise!

Poplar Bluff

Jennie M.

A spacious living room with a wooden ceiling, a fireplace, and a cozy seating area.

15. Lake Wappapello 2 Bedroom Home 1/8 mile to beach and boat ramp

Wappapello

Amber F.

A two-story house with a covered porch, stone facade, and a blue door.

16. Spacious & Secluded Shook Home w/ Private Hot Tub!

Shook

Jessie R.

A cozy living room with wooden walls and ceiling, a large window, a fireplace, and a television.

17. Home Sweet Home, Spacious Sunroom & Fun Deck!

Poplar Bluff

Shirley H.

A two-story house with a front porch, a covered entryway, and a small garden with white flowers.

18. Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy

Dexter

Tammy G.

AED 756 total

includes taxes & fees

10 Nov - 11 Nov

A house with a front porch decorated with hay bales, a scarecrow, and pumpkins.

19. Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff

Poplar Bluff

Melissa W.

AED 963 total

includes taxes & fees

10 Nov - 11 Nov

A modern kitchen with white cabinets, stainless steel appliances, and a granite countertop.

20. Greenway Getaway~Charming 3-bedroom, 3 BA home in the heart of Jackson, Missouri

Jackson

John B M.

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Top Stoddard County Hotel Reviews

Fairfield Inn & Suites by Marriott Cape Girardeau

10/10 Excellent

"I didn't get the receptionist's name, but she was absolutely wonderful! As we were leaving today after our 2-night stay, she asked if we needed ice for our cooler, and then proceeded to fill our cooler with ice and carried it out to our vehicle. So very, very kind, and very much appreciated."

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

8/10 Good

"The room was clean and fresh. But I couldn’t say that about the breakfast area. The food was cold, no coffee, the juice machine was gross, the floor was wet and sticky. Kept running out of food. The trash area stunk around the food. Also the elevator floors were always wet and sticky as well."

Lake Wappapello

10/10 Excellent

"This a cabin in a state park. It was very clean and had newer upgrades. Bring the food you need because it's fairly distance from a grocery. We came later in the day because we needed one night and this was a great price and not a chain hotel which we like. There is a little store not too far from the park. We ordered deli sandwiches from here and picked up some icecream. The sandwiches were delicious and the store had pretty much whatever you might need. The checkin process was great with good communication about which cabin to go to, what the door code was etc... We plan to come back for a longer stay so we can have another evening around the firepit and see all of the stars. Great place to stay."

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Advance Vacations

Room 1

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for Stoddard County vacation homes

1. “Kozy on Kingsway” is a charming 4-bedroom house in Cape -The City of Roses

2. The Cutie Patootie on Helen- Cute, Cozy, Comfortable - 3 BR Home in Dexter, MO

3. “Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau

4. Urban 2-bedroom Escape in Downtown Cape Girardeau

5. 3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau

6. Little Blue Cottage on Spanish

7. Charming, historic Fuerth House in Downtown Cape Girardeau, 2 bedrooms, 1 bath.

8. Cozy 3-bedroom in Wappapello with AC, WiFi and close to the Lake.

9. Private lake, beach & hot tub, romantic getaway or family vaca

10. Camp Stonebass-Lake House-Hottub

11. Hunting / Fishing Cabin at Lake Wappapello

12. Quaint, Beautiful Home next to SEMO and Hospital

13. Doc's Cottage - A-Frame in Piggott, AR

14. 40-Acre Poplar Bluff Nature Lovers Paradise!

15. Lake Wappapello 2 Bedroom Home 1/8 mile to beach and boat ramp

16. Spacious & Secluded Shook Home w/ Private Hot Tub!

17. Home Sweet Home, Spacious Sunroom & Fun Deck!

18. Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy

19. Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff

20. Greenway Getaway~Charming 3-bedroom, 3 BA home in the heart of Jackson, Missouri

Find vacation rentals that suit your style

Top Stoddard County Hotel Reviews

Fairfield Inn & Suites by Marriott Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Drury Inn & Suites Sikeston, MO

Econo Lodge Dexter

Dexter Inn

Lake Wappapello

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