Photo by Ryan Watts

Find hotels in Upstate South Carolina, SC from AED 245
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Our top choices for Upstate South Carolina hotels

Holiday Inn Express Gaffney by IHG
Holiday Inn Express Gaffney by IHGGaffney
8.8 out of 10, Excellent, (486 reviews)
The price is AED 327
AED 356 total
includes taxes & fees
17 May - 18 May

The Inn at Patrick Square
The Inn at Patrick SquareClemson
9.8 out of 10, Exceptional, (845 reviews)
The price is AED 584
AED 648 total
includes taxes & fees
14 May - 15 May

Embassy Suites Greenville Golf Resort & Conference Center
Embassy Suites Greenville Golf Resort & Conference CenterGreenville
9.0 out of 10, Wonderful, (1,201 reviews)
The price is AED 436
AED 479 total
includes taxes & fees
24 May - 25 May

Hampton Inn Greer Greenville, SC
Hampton Inn Greer Greenville, SCGreer
9.6 out of 10, Exceptional, (455 reviews)
The price is AED 511
AED 557 total
includes taxes & fees
14 May - 15 May

Hampton Inn Gaffney
Hampton Inn GaffneyGaffney
8.8 out of 10, Excellent, (710 reviews)
The price is AED 318
AED 347 total
includes taxes & fees
17 May - 18 May

Comfort Inn & Suites Greer - Greenville
Comfort Inn & Suites Greer - GreenvilleGreer
8.6 out of 10, Excellent, (788 reviews)
The price is AED 374
AED 419 total
includes taxes & fees
17 May - 18 May

Inn on the Square, an Ascend Collection Hotel
Inn on the Square, an Ascend Collection HotelUptown Greenwood
9.2 out of 10, Wonderful, (736 reviews)
The price is AED 412
AED 457 total
includes taxes & fees
7 Jun - 8 Jun

Fairfield Inn & Suites Seneca Clemson Univ Area
Fairfield Inn & Suites Seneca Clemson Univ AreaSeneca
9.4 out of 10, Exceptional, (229 reviews)
The price is AED 475
AED 522 total
includes taxes & fees
18 May - 19 May

Best Western Plus Clemson Hotel & Conference Center
Best Western Plus Clemson Hotel & Conference CenterClemson
8.2 out of 10, Very Good, (1,000 reviews)
The price is AED 403
AED 447 total
includes taxes & fees
8 Jun - 9 Jun

Deluxe Inn
Deluxe InnMauldin
10.0 out of 10, Exceptional, (2 reviews)
The price is AED 247
AED 272 total
includes taxes & fees
14 May - 15 May

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
Holiday Inn Express Hotel & Suites Spartanburg-North by IHGSpartanburg
8.6 out of 10, Excellent, (919 reviews)
The price is AED 354
AED 393 total
includes taxes & fees
24 May - 25 May

Clemson University's James F. Martin Inn
Clemson University's James F. Martin InnClemson
9.4 out of 10, Exceptional, (1,008 reviews)
The price is AED 547
AED 607 total
includes taxes & fees
14 May - 15 May

Lakeside Lodge Clemson
Lakeside Lodge ClemsonSeneca
9.0 out of 10, Wonderful, (1,007 reviews)
The price is AED 400
AED 497 total
includes taxes & fees
15 May - 16 May

Tru by Hilton Spartanburg
Tru by Hilton SpartanburgSpartanburg
9.2 out of 10, Wonderful, (892 reviews)
The price is AED 339
AED 377 total
includes taxes & fees
31 May - 1 Jun

Hampton Inn Easley
Hampton Inn EasleyEasley
9.2 out of 10, Wonderful, (708 reviews)
The price is AED 449
AED 498 total
includes taxes & fees
7 Jun - 8 Jun

The Abernathy of Clemson
The Abernathy of ClemsonClemson
9.6 out of 10, Exceptional, (598 reviews)
The price is AED 499
AED 554 total
includes taxes & fees
17 May - 18 May

Quality Inn Clinton - Laurens I-26
Quality Inn Clinton - Laurens I-26Clinton
7.4 out of 10, Good, (548 reviews)
The price is AED 231
AED 271 total
includes taxes & fees
7 Jun - 8 Jun

Days Inn by Wyndham Anderson
Days Inn by Wyndham AndersonAnderson
8.0 out of 10, Very Good, (1,026 reviews)
The price is AED 250
AED 277 total
includes taxes & fees
26 May - 27 May

Microtel Inn & Suites by Wyndham Anderson/Clemson
Microtel Inn & Suites by Wyndham Anderson/ClemsonAnderson
8.2 out of 10, Very Good, (1,011 reviews)
The price is AED 309
AED 343 total
includes taxes & fees
19 May - 20 May

Comfort Suites At WestGate Mall
Comfort Suites At WestGate MallSpartanburg
8.2 out of 10, Very Good, (1,014 reviews)
The price is AED 329
AED 373 total
includes taxes & fees
7 Jun - 8 Jun
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Vacation Rentals in Upstate South Carolina
Cabin

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott BonvoySeneca
9.8 out of 10, Exceptional, (73 reviews)
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Stay near popular Upstate South Carolina attractions
Learn more about Upstate South Carolina
Venture to sights like Discovery Island Water Park and Heritage Park as you discover Upstate South Carolina.

Photo by Ryan Watts
Open Photo by Ryan Watts
Top Upstate South Carolina Hotel Reviews

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
2/10 Terrible
More cheap stays in Upstate South Carolina

Sleep Inn Spartanburg Southwest
501 South Blackstock Rd Spartanburg SC
The price is AED 221 per night from Jun 7 to Jun 8
AED 221
AED 245 total
7 Jun - 8 Jun
includes taxes & fees
6/10 (600 reviews)
Hotels in Upstate South Carolina with star-rating

4 Star Hotels
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