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Find hotels in Upstate South Carolina, SC from AED 245
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Go beyond your typical stay in Upstate South Carolina
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Our top choices for Upstate South Carolina hotels

Carolina Inn Anderson Clemson Area
Carolina Inn Anderson Clemson AreaAnderson
The price is AED 202
AED 224 total
includes taxes & fees
14 May - 15 May

Deluxe Inn
Deluxe InnMauldin
10.0 out of 10, Exceptional, (2 reviews)
The price is AED 247
AED 272 total
includes taxes & fees
14 May - 15 May

Clemson University's James F. Martin Inn
Clemson University's James F. Martin InnClemson
9.4 out of 10, Exceptional, (1,008 reviews)
The price is AED 547
AED 607 total
includes taxes & fees
14 May - 15 May

Carolina Camp Cedar
Carolina Camp CedarPickens
10.0 out of 10, Exceptional, (3 reviews)
The price is AED 584
AED 953 total
includes taxes & fees
14 May - 15 May

Lakeside Lodge Clemson
Lakeside Lodge ClemsonSeneca
9.0 out of 10, Wonderful, (1,007 reviews)
The price is AED 400
AED 497 total
includes taxes & fees
14 May - 15 May

Quality Inn Seneca Clemson Area US-123
Quality Inn Seneca Clemson Area US-123Downtown
8.0 out of 10, Very Good, (699 reviews)
The price is AED 319
AED 374 total
includes taxes & fees
28 May - 29 May

Inn on the Square, an Ascend Collection Hotel
Inn on the Square, an Ascend Collection HotelUptown Greenwood
9.2 out of 10, Wonderful, (736 reviews)
The price is AED 439
AED 487 total
includes taxes & fees
31 May - 1 Jun

Fairfield Inn & Suites Seneca Clemson Univ Area
Fairfield Inn & Suites Seneca Clemson Univ AreaSeneca
9.4 out of 10, Exceptional, (229 reviews)
The price is AED 475
AED 522 total
includes taxes & fees
17 May - 18 May

Hampton Inn Gaffney
Hampton Inn GaffneyGaffney
8.8 out of 10, Excellent, (710 reviews)
The price is AED 318
AED 347 total
includes taxes & fees
17 May - 18 May

Clemson Memorabilia House
Clemson Memorabilia HouseClemson
9.6 out of 10, Exceptional, (10 reviews)
The price is AED 327
AED 872 total
includes taxes & fees
17 May - 18 May

Hampton Inn Greer Greenville, SC
Hampton Inn Greer Greenville, SCGreer
9.6 out of 10, Exceptional, (454 reviews)
The price is AED 511
AED 557 total
includes taxes & fees
7 Jun - 8 Jun

Best Western Plus Clemson Hotel & Conference Center
Best Western Plus Clemson Hotel & Conference CenterClemson
8.2 out of 10, Very Good, (1,000 reviews)
The price is AED 403
AED 447 total
includes taxes & fees
31 May - 1 Jun

Comfort Inn & Suites Greer - Greenville
Comfort Inn & Suites Greer - GreenvilleGreer
8.6 out of 10, Excellent, (788 reviews)
The price is AED 374
AED 419 total
includes taxes & fees
17 May - 18 May

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHGAnderson
9.2 out of 10, Wonderful, (614 reviews)
The price is AED 404
AED 448 total
includes taxes & fees
24 May - 25 May

Microtel Inn & Suites by Wyndham Anderson/Clemson
Microtel Inn & Suites by Wyndham Anderson/ClemsonAnderson
8.2 out of 10, Very Good, (1,011 reviews)
The price is AED 309
AED 343 total
includes taxes & fees
19 May - 20 May

Quality Inn Clinton - Laurens I-26
Quality Inn Clinton - Laurens I-26Clinton
7.4 out of 10, Good, (548 reviews)
The price is AED 231
AED 271 total
includes taxes & fees
7 Jun - 8 Jun

Comfort Inn & Suites Clemson - University Area
Comfort Inn & Suites Clemson - University AreaClemson
8.4 out of 10, Very Good, (1,001 reviews)
The price is AED 393
AED 437 total
includes taxes & fees
24 May - 25 May

Tru by Hilton Seneca Clemson
Tru by Hilton Seneca ClemsonSeneca
9.2 out of 10, Wonderful, (839 reviews)
The price is AED 419
AED 461 total
includes taxes & fees
24 May - 25 May

Hampton Inn & Suites Clinton - I-26
Hampton Inn & Suites Clinton - I-26Clinton
9.0 out of 10, Wonderful, (736 reviews)
The price is AED 452
AED 506 total
includes taxes & fees
31 May - 1 Jun

The Inn at Patrick Square
The Inn at Patrick SquareClemson
9.8 out of 10, Exceptional, (845 reviews)
The price is AED 584
AED 648 total
includes taxes & fees
14 May - 15 May
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Vacation Rentals in Upstate South Carolina
Cabin

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott BonvoySeneca
9.8 out of 10, Exceptional, (72 reviews)
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Stay near popular Upstate South Carolina attractions
Learn more about Upstate South Carolina
Venture to sights like Discovery Island Water Park and Heritage Park as you discover Upstate South Carolina.

Photo by Ryan Watts
Open Photo by Ryan Watts
Top Upstate South Carolina Hotel Reviews

Best Western Plus Greenville I-385 Inn & Suites
6/10 Okay
More cheap stays in Upstate South Carolina

Sleep Inn Spartanburg Southwest
501 South Blackstock Rd Spartanburg SC
The price is AED 221 per night from Jun 7 to Jun 8
AED 221
AED 245 total
7 Jun - 8 Jun
includes taxes & fees
6/10 (600 reviews)
Hotels in Upstate South Carolina with star-rating

4 Star Hotels
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