Photo by Ryan Watts

Find hotels in Upstate South Carolina, SC from AED 261
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Our top choices for Upstate South Carolina hotels

Home2 Suites by Hilton Anderson Downtown
Home2 Suites by Hilton Anderson DowntownAnderson
9.4 out of 10, Exceptional, (231 reviews)
The price is AED 514
AED 570 total
includes taxes & fees
29 Mar - 30 Mar

Embassy Suites Greenville Golf Resort & Conference Center
Embassy Suites Greenville Golf Resort & Conference CenterGreenville
9.0 out of 10, Wonderful, (1,125 reviews)
The price is AED 358
AED 394 total
includes taxes & fees
5 Apr - 6 Apr

Hampton Inn Easley
Hampton Inn EasleyEasley
9.2 out of 10, Wonderful, (693 reviews)
The price is AED 509
AED 565 total
includes taxes & fees
5 Apr - 6 Apr

Carolina Camp Cedar
Carolina Camp CedarPickens
10.0 out of 10, Exceptional, (3 reviews)
The price is AED 356
AED 701 total
includes taxes & fees
24 Mar - 25 Mar

Inn on the Square, an Ascend Collection Hotel
Inn on the Square, an Ascend Collection HotelUptown Greenwood
9.2 out of 10, Wonderful, (725 reviews)
The price is AED 434
AED 482 total
includes taxes & fees
12 Apr - 13 Apr

Hampton Inn Greer Greenville, SC
Hampton Inn Greer Greenville, SCGreer
9.6 out of 10, Exceptional, (441 reviews)
The price is AED 511
AED 557 total
includes taxes & fees
28 Mar - 29 Mar

Lakeside Lodge Clemson
Lakeside Lodge ClemsonSeneca
9.0 out of 10, Wonderful, (1,002 reviews)
The price is AED 400
AED 497 total
includes taxes & fees
24 Mar - 25 Mar

Holiday Inn Express Gaffney by IHG
Holiday Inn Express Gaffney by IHGGaffney
8.8 out of 10, Excellent, (458 reviews)
The price is AED 386
AED 420 total
includes taxes & fees
27 Mar - 28 Mar

The Inn at Patrick Square
The Inn at Patrick SquareClemson
9.8 out of 10, Exceptional, (813 reviews)
The price is AED 584
AED 648 total
includes taxes & fees
31 Mar - 1 Apr

Fairfield Inn & Suites by Marriott Greenville Simpsonville
Fairfield Inn & Suites by Marriott Greenville SimpsonvilleSimpsonville
9.0 out of 10, Wonderful, (685 reviews)
The price is AED 340
AED 374 total
includes taxes & fees
5 Apr - 6 Apr

Clemson University's James F. Martin Inn
Clemson University's James F. Martin InnClemson
9.4 out of 10, Exceptional, (987 reviews)
The price is AED 547
AED 607 total
includes taxes & fees
24 Mar - 25 Mar

Quality Inn Seneca Clemson Area US-123
Quality Inn Seneca Clemson Area US-123Downtown
8.0 out of 10, Very Good, (689 reviews)
The price is AED 286
AED 337 total
includes taxes & fees
29 Mar - 30 Mar

Hampton Inn Gaffney
Hampton Inn GaffneyGaffney
8.8 out of 10, Excellent, (693 reviews)
The price is AED 317
AED 345 total
includes taxes & fees
19 Apr - 20 Apr

Best Western Travelers Rest Greenville
Best Western Travelers Rest GreenvilleTravelers Rest
7.6 out of 10, Good, (1,005 reviews)
The price is AED 323
AED 356 total
includes taxes & fees
29 Mar - 30 Mar

Best Western Plus Clemson Hotel & Conference Center
Best Western Plus Clemson Hotel & Conference CenterClemson
8.2 out of 10, Very Good, (1,002 reviews)
The price is AED 381
AED 423 total
includes taxes & fees
3 Apr - 4 Apr

Tru by Hilton Spartanburg
Tru by Hilton SpartanburgSpartanburg
9.2 out of 10, Wonderful, (863 reviews)
The price is AED 337
AED 374 total
includes taxes & fees
29 Mar - 30 Mar

La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.
La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.Greenville
8.8 out of 10, Excellent, (149 reviews)
The price is AED 291
AED 330 total
includes taxes & fees
25 Mar - 26 Mar

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHGAnderson
9.0 out of 10, Wonderful, (600 reviews)
The price is AED 378
AED 420 total
includes taxes & fees
5 Apr - 6 Apr

Spartanburg Marriott
Spartanburg MarriottSpartanburg
8.6 out of 10, Excellent, (1,001 reviews)
The price is AED 433
AED 481 total
includes taxes & fees
12 Apr - 13 Apr

Best Western Spartanburg Northwest
Best Western Spartanburg NorthwestSpartanburg
8.2 out of 10, Very Good, (858 reviews)
The price is AED 325
AED 360 total
includes taxes & fees
25 Mar - 26 Mar
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Vacation Rentals in Upstate South Carolina
Cabin

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott BonvoySeneca
9.8 out of 10, Exceptional, (66 reviews)
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Venture to sights like Heritage Park and Conestee Nature Preserve as you discover Upstate South Carolina.

Photo by Ryan Watts
Open Photo by Ryan Watts
Top Upstate South Carolina Hotel Reviews

Hyatt Regency Greenville
10/10 Excellent
More cheap stays in Upstate South Carolina

Urban Boutique Hotel, BW Signature Collection
536 Wade Hampton Blvd Greenville SC
The price is AED 237 per night from Apr 5 to Apr 6
AED 237
AED 261 total
5 Apr - 6 Apr
includes taxes & fees
8/10 Very Good! (978 reviews)
Hotels in Upstate South Carolina with star-rating

4 Star Hotels
11 properties
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Other Hotels near Upstate South Carolina, South Carolina
Explore more hotels
- La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.
- Aloft Greenville Downtown
- Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
- Mint House Greenville Downtown by Kasa
- Comfort Inn Greenville - Haywood Mall
- The Shepherd Hotel Downtown Clemson
- Inn @ Clemson
- Comfort Suites At WestGate Mall
- HomeTowne Studios by Red Roof Spartanburg - Asheville Highway
- Best Western Spartanburg Northwest
- Clemson University's James F. Martin Inn





































































































































