Search Vacation Homes in Upstate South Carolina

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Compare 973 Vacation Homes in Upstate South Carolina with updated reviews, rates, and availability.

Lakehouse Retreat with dock, paddle boat, canoe & kayaks!

10.0 out of 10, Exceptional, (170)
"Had a great time on the dock each night "
Lakehouse Retreat with dock, paddle boat, canoe & kayaks!

6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water.

9.8 out of 10, Exceptional, (141)
"The property was clean, loaded with everything you need, and gave our large group room for privacy along with lots of time together around the beautiful dining table, the fire pit, and the pool table. Awesome stay and the host was wonderful to work with. Beautiful lake views as well!!"
6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water.

Lakefront Home on Lake Hartwell, private covered dock, ~16 miles from Clemson

10.0 out of 10, Exceptional, (47)
"Wonderful location, amenities and family space !"
The price is AED 643
AED 2,030 total
includes taxes & fees
3 Jun - 4 Jun
Lakefront Home on Lake Hartwell, private covered dock, ~16 miles from Clemson

Keowee Key Townhouse- Lake, great deck, outdoor firetable & CLEMSON FOOTBALL!

10.0 out of 10, Exceptional, (14)
"Excellent and a great family experience! Plenty of usable space!"
Keowee Key Townhouse- Lake, great deck, outdoor firetable & CLEMSON FOOTBALL!

Beautiful home in the Heart of Five Forks, Simpsonville!

10.0 out of 10, Exceptional, (26)
"Exactly what we needed very nice and clean place in a good neighborhood "
Beautiful home in the Heart of Five Forks, Simpsonville!

3 Bedroom/2 Full Bath House in Seneca, SC. 4 miles from Clemson Campus!

8.0 out of 10, Very Good, (2)
"Communication with Katie was amazing from the get go! The house was clean and plenty big enough for the 6 of us that stayed. Plenty of towels provided, beds were comfortable, and it was easy to connect the tv to a hotspot if we wanted to. Definitely will be keeping this on my list of places to stay in Clemson! "
3 Bedroom/2 Full Bath House in Seneca, SC. 4 miles from Clemson Campus!

Quiet cove, deep water, minutes to Clemson, pet friendly, easy path to the dock

9.6 out of 10, Exceptional, (164)
"Gorgeous spot on the lake, nice and quiet, but still only a couple minutes to the store. Lots of space and a great deck. "
Quiet cove, deep water, minutes to Clemson, pet friendly, easy path to the dock

Cozy Pet Friendly Cottage, 2 story Deep Water Dock - bring your boat!

10.0 out of 10, Exceptional, (93)
"Home was very well stocked and beautiful location!"
Cozy Pet Friendly Cottage, 2 story Deep Water Dock - bring your boat!

4 Mi to Dtwn: Home w/ Fire Pit in Greenville

10.0 out of 10, Exceptional, (3)
"Great place to stay, cool and comfortable features. My kids play piano and were thrilled there was a piano there. The beds were comfortable and the master bath shower was really nicely finished."
4 Mi to Dtwn: Home w/ Fire Pit in Greenville

Lakefront Gem w/ Games in Westminster!

10.0 out of 10, Exceptional, (1)
"Our stay was wonderful. The kids had an absolute blast and the cabin was perfect!"
Lakefront Gem w/ Games in Westminster!

Lakefront Keowee Home w/ Dock ~ 14 Mi to Clemson

10.0 out of 10, Exceptional, (62)
"House was exactly as pictured and described. Communication from host was excellent and prompt. Very good location for Clemson graduation!"
Lakefront Keowee Home w/ Dock ~ 14 Mi to Clemson

Great weekend getaway just a mile from downtown!

10.0 out of 10, Exceptional, (12)
"Perfect place for a short stay near Clemson - walkable to downtown and the university!!"
Great weekend getaway just a mile from downtown!

Clemson House 1 mile from University & Stadium!

9.4 out of 10, Exceptional, (17)
"Came to visit my daughter at Clemson for the weekend. The house was close to campus. Easy check in and out and perfect for what we needed. Would stay here again!"
The price is AED 661
AED 1,398 total
includes taxes & fees
4 Jun - 5 Jun
Clemson House 1 mile from University & Stadium!

New! Boutique Tiny Home on the Saluda River

9.8 out of 10, Exceptional, (66)
"Tiny home on the River! Comfy bed and great water pressure in shower. We love how close this home is to Greenville,SC. The outdoor center that this place is located on did not have live music or events happening while we were here. We could definitely see how this is a great summer spot with access to tubing/river access. We would definitely come back to this. Our dogs loved It. Only setback is you are so close to the other homes that if you’re wanting privacy you’re having to share common...
New! Boutique Tiny Home on the Saluda River

Lake House Near Clemson Private Boat Dock WiFi 65" TV Grill Kayaks Deep Water

9.8 out of 10, Exceptional, (147)
"Great property, really secluded and right on the lake. The road coming in makes you feel like you're in a slasher movie but other than that, the place was nice and clean. Recommend."
Lake House Near Clemson Private Boat Dock WiFi 65" TV Grill Kayaks Deep Water

Lakefront home w/covered dock*Pool table*Kayak/SUP*11mi to Clemson*Hot tub

10.0 out of 10, Exceptional, (45)
"Loved this home. Lots of room, great area, beautiful views. "
Lakefront home w/covered dock*Pool table*Kayak/SUP*11mi to Clemson*Hot tub

The Rabbit Hole - cozy retreat in downtown Travelers Rest.

9.6 out of 10, Exceptional, (21)
"It was exactly as advertised - Joy was responsive when we needed her."
The Rabbit Hole - cozy retreat in downtown Travelers Rest.

~2 Bedroom Cozy Gem 💎 5 minutes from Downtown Spartanburg~

10.0 out of 10, Exceptional, (36)
"super cute very clean huge yard safe community…. Host was amazing!"
The price is AED 408
AED 824 total
includes taxes & fees
15 Jun - 16 Jun
~2 Bedroom Cozy Gem 💎 5 minutes from Downtown Spartanburg~

Whole House

10.0 out of 10, Exceptional, (45)
"Beautiful, well kept, close to everything you could need. Will definitely look this up next time we are in the area. "
Whole House

Almost Level Lot, Dock with Sun Deck, Pontoon rental, (25 min. from Clemson)

9.8 out of 10, Exceptional, (128)
"Very happy with our long weekend stay at this property. The location is perfect on a quiet cove with great dock and deep water. The house had everything we needed, was very comfortable, and is close to grocery stores and restaurants. Very easy to find. Jon was one of the best VRBO hosts I have encountered - super communicative, very helpful, and wanting to make sure we enjoyed the best stay that we could. Highly recommend, particularly for families."
Almost Level Lot, Dock with Sun Deck, Pontoon rental, (25 min. from Clemson)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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