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Search Vacation Homes in Upstate South Carolina

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Check prices for these dates

Next weekend
19 Dec - 21 Dec
In two weeks
26 Dec - 28 Dec
In one month
9 Jan - 11 Jan
In two months
6 Feb - 8 Feb

Vacation Homes in Upstate South Carolina

Private kitchen
Cozy 2BR Near Furman & Downtown, Fenced Yard

Vacation Home in Greenville

10.0 out of 10, Exceptional, (2)
"delightful house on a very mellow street. super easy access to downtown, a grocery store close, beautiful backyard for the dog, lovely kitchen. i was in town for my anniversary week and my partner and i enjoyed the stay very much. hosts were helpful and communicative, the house was exactly as described and we literally had zero issues. i have no problem recommending this house strongly! "
United States
jon b.
The price is AED 323
AED 800 total
includes taxes & fees
5 Jan - 6 January 2026
Cozy 2BR Near Furman & Downtown, Fenced Yard
Interior
Cozy, Updated 2BR/2.5BA End-Unit Townhome, Greer SC

Vacation Home in Greer

10.0 out of 10, Exceptional, (3)
"House was perfect for our needs. Spacious and clean. Easy to access, good parking and good communication with host. "
United States
Christopher A.
The price is AED 496
AED 1,297 total
includes taxes & fees
15 Dec - 16 Dec
Cozy, Updated 2BR/2.5BA End-Unit Townhome, Greer SC
Smart TV
Cozy Stays King Size Bed Full Kitchen Work

Vacation Home in Spartanburg

10.0 out of 10, Exceptional, (3)
"SHEENA WAS AN AWESOME HOSTESS!."
United States
TOM w.
The price is AED 496
AED 1,435 total
includes taxes & fees
5 Jan - 6 January 2026
Cozy Stays King Size Bed Full Kitchen Work
Outdoor dining
Secluded Yurt Hideaway 10 min to Table Rock

Vacation Home in cleveland

9.6 out of 10, Exceptional, (7)
"The place is awesome! I don’t usually leave comments but this place is worth the visit."
United States
Michael
The price is AED 364
AED 1,228 total
includes taxes & fees
9 Dec - 10 Dec
Secluded Yurt Hideaway 10 min to Table Rock
Fridge, microwave, oven, stovetop
The Blue Bungalow by Unity Park - Newly Renovated

Vacation Home in Woodside Cotton Mill Village Historic District

9.8 out of 10, Exceptional, (81)
"Thand comfortable e bungalow was great ,clean,updated "
United States
Mark
The price is AED 271
AED 722 total
includes taxes & fees
9 Dec - 10 Dec
The Blue Bungalow by Unity Park - Newly Renovated
Fridge, microwave, oven, stovetop
Skyline Split A Retreat Close to Everything You Need! Quiet, Clean & Convenient.

Vacation Home in Woodside Cotton Mill Village Historic District

2.0 star property
10.0 out of 10, Exceptional, (1)
"Check-in was smooth as could, be. The place itself was spotless, clean, and perfect for our stay. Highly recommend Old Europe for coffee and a pastry nearby. "
United States
Matthew K.
The price is AED 331
AED 800 total
includes taxes & fees
27 Dec - 28 Dec
Skyline Split A Retreat Close to Everything You Need! Quiet, Clean & Convenient.
Terrace/patio
Welcome To Downtown Pickens close to Clemson and Lake Keowee

Vacation Home in Pickens

9.8 out of 10, Exceptional, (30)
"We enjoyed our stay at this lovely home! Checking was easy and kitchen was roomy and met our needs."
United States
Carla B.
The price is AED 397
AED 966 total
includes taxes & fees
9 Dec - 10 Dec
Welcome To Downtown Pickens close to Clemson and Lake Keowee
Fridge, microwave, oven, stovetop
Spacious 4-bedroom home in charming Travelers Rest with WiFi & Firepit.

Vacation Home in Travelers Rest

10.0 out of 10, Exceptional, (16)
"Great location, clean place, great communication would come back again."
United States
Jeff S.
The price is AED 459
AED 1,220 total
includes taxes & fees
5 Jan - 6 January 2026
Spacious 4-bedroom home in charming Travelers Rest with WiFi & Firepit.
Interior
Pet-Friendly Cabin in Marietta w/ Porch Swings

Vacation Home in Cleveland

10.0 out of 10, Exceptional, (1)
"Accurate listing, easy to find! "
United States
Beth T.
The price is AED 303
AED 968 total
includes taxes & fees
9 Dec - 10 Dec
Pet-Friendly Cabin in Marietta w/ Porch Swings
Exterior detail
Apt. near Downtown Greenville (2BR/1BA, 3 beds)

Vacation Home in Greenville

10.0 out of 10, Exceptional, (11)
"It was clean and quiet..I will stay here again. "
United States
Kimberly S.
The price is AED 332
AED 607 total
includes taxes & fees
9 Dec - 10 Dec
Apt. near Downtown Greenville (2BR/1BA, 3 beds)
Property grounds
Hobbit Hideaway - Do Something Different!

Vacation Home in Marietta

10.0 out of 10, Exceptional, (50)
"Very well appointed."
United States
Sara P.
The price is AED 248
AED 576 total
includes taxes & fees
10 Dec - 11 Dec
Hobbit Hideaway - Do Something Different!
Fridge, microwave, oven, stovetop
6 Min>Clemson - 1kMbps - Keyless Entry - Office Space

Vacation Home in Pendleton

10.0 out of 10, Exceptional, (4)
"Clean and comfortable. Close to campus"
United States
Russ C.
The price is AED 459
AED 1,476 total
includes taxes & fees
16 Dec - 17 Dec
6 Min>Clemson - 1kMbps - Keyless Entry - Office Space
Dining
Chic 3BR Home: Pet Friendly, Near Furman & Parks

Vacation Home in Greenville

9.6 out of 10, Exceptional, (4)
"Great for our visit"
United States
Robert B.
The price is AED 335
AED 1,092 total
includes taxes & fees
11 Dec - 12 Dec
Chic 3BR Home: Pet Friendly, Near Furman & Parks
Fridge, microwave, oven, stovetop
Cozy Bamboo Retreat, Modern Comforts Duplex

Vacation Home in Wellford

2.0 star property
9.8 out of 10, Exceptional, (7)
"Reasonably priced and the owner was very communicative. They provided the little things to make our stay enjoyable. "
United States
david m.
The price is AED 386
AED 1,036 total
includes taxes & fees
1 Jan - 2 January 2026
Cozy Bamboo Retreat, Modern Comforts Duplex
Private kitchen
Family-Friendly 3/2 Home Near Prisma, Fenced Yard

Vacation Home in Greenville

10.0 out of 10, Exceptional, (5)
"The place was perfect! Had everything we needed and was extremely clean!"
United States
Matthew S.
The price is AED 364
AED 1,111 total
includes taxes & fees
22 Dec - 23 Dec
Family-Friendly 3/2 Home Near Prisma, Fenced Yard
Fridge, microwave, oven, stovetop
Private family, pet friendly with fenced yard near Limestone College and Outlets

Vacation Home in Gaffney

9.8 out of 10, Exceptional, (24)
"It is a really nice place and in a quiet area. Very cute backyard. Would stay again!! "
United States
Jessica S.
The price is AED 294
AED 745 total
includes taxes & fees
19 Dec - 20 Dec
Private family, pet friendly with fenced yard near Limestone College and Outlets
Outdoor spa tub
⭐️Hot Tub⭐️ Luxury Getaway Near GSP Airport Downtown Greer Greenville Spartanburg

Vacation Home in Lyman

10.0 out of 10, Exceptional, (40)
"We loved this place! Clean and beautiful. The snacks and the candle were just perfect to make our stay the best."
United States
Molly M.
The price is AED 331
AED 754 total
includes taxes & fees
15 Dec - 16 Dec
⭐️Hot Tub⭐️ Luxury Getaway Near GSP Airport Downtown Greer Greenville Spartanburg
Private kitchen
Downtown Easley Home

Vacation Home in Easley

7.8 out of 10, Good, (6)
"The house was great for our one night stay. The house was clean and stocked. We had to leave early and didn't spend the entire night. But the host was gracious and easy to communicate with. Would recommend!"
United States
CANDY B.
The price is AED 327
AED 869 total
includes taxes & fees
9 Dec - 10 Dec
Downtown Easley Home
Outdoor dining
The Rustic Rectangle

Vacation Home in Pendleton

10.0 out of 10, Exceptional, (10)
"Cozy, clean and quiet! Loved that we could have our dogs stay with us! "
United States
Jennifer T.
The price is AED 489
AED 1,049 total
includes taxes & fees
9 Dec - 10 Dec
The Rustic Rectangle
TV
Sleek 3BR Pet-Friendly Oasis, Close to City

Vacation Home in Taylors

10.0 out of 10, Exceptional, (4)
"Very clean. Wonderful location and private. "
United States
Paula
The price is AED 408
AED 1,184 total
includes taxes & fees
10 Dec - 11 Dec
Sleek 3BR Pet-Friendly Oasis, Close to City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Upstate South Carolina Hotel Reviews

Drury Inn & Suites Greenville

Drury Inn & Suites Greenville

10/10 Excellent
"Very nice amenities and rooms. Staff was super friendly and very helpful when needed. We will definitely stay at another Drury Inn when traveling or needing a hotel"
Blair 2-night trip
Posted 20 hours ago
Drury Inn & Suites Greenville

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