Find hotels in Wykoff, MN from AED 216

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
24 Dec - 25 Dec
Tomorrow
25 Dec - 26 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Wykoff hotels

Front of property
Stone Mill Hotel & Suites

Stone Mill Hotel & Suites

Stone Mill Hotel & Suites
3.0 star property
Lanesboro
9.2 out of 10, Wonderful, (663)
Experience outdoor adventure from this welcoming retreat offering hiking trails, kayaking and cross-country skiing nearby. Enjoy complimentary breakfast, WiFi and parking while staying minutes from Commonweal Theatre and Lanesboro Arts Center.
"Great service, location"
United States
Eric
The price is AED 386
AED 414 total
includes taxes & fees
25 Dec - 26 Dec
Stone Mill Hotel & Suites
Loft | Iron/ironing board, free WiFi
Country Lodge inn

Country Lodge inn

Country Lodge inn
2.0 star property
Harmony
9.0 out of 10, Wonderful, (39)
Surrounded by Minnesota countryside, this welcoming lodge offers convenient access to Slim's Woodshed and Museum. Enjoy the tranquil setting with free WiFi and parking while exploring nearby Niagara Cave.
"Old motel but clean, with friendly owners."
United States
Fred
The price is AED 490
AED 562 total
includes taxes & fees
1 Jan - 2 January 2026
Country Lodge inn
Deluxe Double Room | Down comforters, pillowtop beds, individually decorated
Country Trails Inn & Suites

Country Trails Inn & Suites

Country Trails Inn & Suites
2.0 star property
Preston
9.4 out of 10, Exceptional, (102)
Escape to this golf hotel in Preston featuring a charming winery. After a refreshing morning swim, relax in the hot tub. Free amenities include breakfast, WiFi, and parking. The Old Barn Resort Course is nearby.
"Great desk host, nice property, comfortable rooms, nice breakfast & dining room within walking from Casey’s gas & market. "
United States
Nancy
The price is AED 418
AED 462 total
includes taxes & fees
1 Jan - 2 January 2026
Country Trails Inn & Suites
Front of property
White Valley Motel

White Valley Motel

White Valley Motel
2.5 star property
St. Charles
5.6 out of 10, (128)
Located in St. Charles, this welcoming motel offers free WiFi and parking with 24-hour front desk service. Enjoy easy access to the scenic Whitewater River while having a comfortable base for exploring the area.
"Very nice owner i wil come back again thank you.. "
United States
Rolando
The price is AED 253
AED 283 total
includes taxes & fees
25 Dec - 26 Dec
White Valley Motel
Lobby
Americas Best Value Inn & Suites Spring Valley

Americas Best Value Inn & Suites Spring Valley

Americas Best Value Inn & Suites Spring Valley
2.0 star property
Spring Valley
8.2 out of 10, Very Good, (434)
Enjoy free morning meals and convenient parking at this well-maintained property. Work out in the fitness center after exploring nearby Masonic Park and Four Daughters Vineyard & Winery. Clean rooms and business-friendly amenities create a comfortable base for your stay.
"The place was very clean, very quiet and the staff was extremely helpful. We will be back"
United States
Melissa
The price is AED 312
AED 345 total
includes taxes & fees
19 Jan - 20 January 2026
Americas Best Value Inn & Suites Spring Valley
Front of property
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3.0 star property
Rochester
7.2 out of 10, Good, (1025)
Located within a 10-minute drive of Mayo Clinic, this Rochester hotel offers complimentary perks including daily buffet breakfast, Wi-Fi, and self parking. Guests can maintain routines at the fitness center while enjoying clean, comfortable rooms praised by travelers.
"Staff was courteous and breakfast was well stocked."
United States
Doug
The price is AED 258
AED 297 total
includes taxes & fees
26 Dec - 27 Dec
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Desk, blackout drapes, iron/ironing board, free cribs/infant beds
AmericInn by Wyndham Rochester

AmericInn by Wyndham Rochester

AmericInn by Wyndham Rochester
2.0 star property
Rochester
8.8 out of 10, Excellent, (1004)
Enjoy convenient access to Mayo Clinic from this welcoming hotel offering free breakfast, WiFi, and parking. Unwind in the indoor pool and hot tub after a busy day. Clean rooms and friendly staff ensure a pleasant stay near local attractions.
"Enjoyed our stay, rated breakfast as a erage as we did not try it."
United States
jeanne
The price is AED 278
AED 320 total
includes taxes & fees
28 Dec - 29 Dec
AmericInn by Wyndham Rochester
Reception
America's Stay Inn Stewartville

America's Stay Inn Stewartville

America's Stay Inn Stewartville
2.5 star property
Stewartville
8.0 out of 10, Very Good, (419)
Just 15 minutes from Mayo Clinic, this Stewartville hotel provides complimentary breakfast, Wi-Fi and parking. Guests appreciate the clean rooms and convenient access to Maple Valley Golf & Country Club.
"Room was nicer and furnished better than most high end places I’ve stayed at. It’s a small hotel on a busy road, but comfortable bed and clean."
Canada
Robert
America's Stay Inn Stewartville
Exterior
Holiday Inn Express Rochester South - Mayo Area by IHG

Holiday Inn Express Rochester South - Mayo Area by IHG

Holiday Inn Express Rochester South - Mayo Area by IHG
2.5 star property
Rochester
8.8 out of 10, Excellent, (1000)
This welcoming hotel puts you just 10 minutes from Mayo Clinic. Start each morning with complimentary breakfast before unwinding in the hot tub. The fitness center, free parking, and helpful staff ensure a comfortable, convenient visit.
"Clean rooms, very friendly staff and just all around homey "
United States
Kathy
The price is AED 268
AED 309 total
includes taxes & fees
1 Jan - 2 January 2026
Holiday Inn Express Rochester South - Mayo Area by IHG
Reception
Hampton Inn Rochester-South

Hampton Inn Rochester-South

Hampton Inn Rochester-South
2.5 star property
Rochester
9.0 out of 10, Wonderful, (1001)
Enjoy tranquility at this Rochester hotel with an indoor pool and hot tub to unwind after Mayo Clinic visits. Free WiFi, parking, and breakfast await, with Olmsted County Fairgrounds and Apache Mall nearby. Guests praise the quiet atmosphere and helpful staff.
"We had a wonderful stay!"
United States
Sarah
The price is AED 296
AED 340 total
includes taxes & fees
24 Jan - 25 January 2026
Hampton Inn Rochester-South
Exterior
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG
3.5 star property
Downtown Rochester
8.8 out of 10, Excellent, (892)
Located within walking distance of Mayo Clinic, this hotel offers quiet rooms and convenient access to Rochester Public Library. The on-site Crave restaurant serves American cuisine, while the rooftop terrace provides a serene escape after a busy day.
"Room was clean and comfortable Staff courteous Comfortable beds Great restaurant"
United States
Matney
The price is AED 283
AED 326 total
includes taxes & fees
24 Jan - 25 January 2026
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Serves lunch, dinner, and happy hour
AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic
3.0 star property
Rochester
8.2 out of 10, Very Good, (1146)
This peaceful hotel offers an indoor pool and 24-hour fitness center just 5 minutes from Mayo Clinic. Enjoy free breakfast and parking, plus convenient dining at Crooked Pint Ale House. Rooms include refrigerators and microwaves for added comfort.
"Good price, room clean, descent breakfast. I have stayed here several time"
United States
Amy M
The price is AED 271
AED 312 total
includes taxes & fees
2 Jan - 3 January 2026
AmericInn by Wyndham Rochester Near Mayo Clinic
Reception
Spark by Hilton Rochester South

Spark by Hilton Rochester South

Spark by Hilton Rochester South
3.0 star property
Rochester
9.4 out of 10, Exceptional, (326)
This inviting hotel features a refreshing indoor pool and convenient fitness center. Just 10 minutes from Mayo Clinic and Saint Marys Campus, it offers free breakfast, WiFi and parking. Staff receive high marks from travelers for their helpfulness.
"Great place"
United States
Abidemi
The price is AED 259
AED 298 total
includes taxes & fees
4 Jan - 5 January 2026
Spark by Hilton Rochester South
Free daily full breakfast
Quality Inn & Suites Mayo Clinic Area

Quality Inn & Suites Mayo Clinic Area

Quality Inn & Suites Mayo Clinic Area
2.5 star property
Rochester
8.8 out of 10, Excellent, (830)
Just a 5-minute drive from Mayo Clinic, this quiet hotel offers free breakfast, WiFi, and parking. Located in a great neighborhood near restaurants and shops, with clean rooms and helpful staff. Apache Mall and Olmsted County Fairgrounds are nearby.
"Very clean and so helpful "
United States
Mark
The price is AED 248
AED 289 total
includes taxes & fees
2 Jan - 3 January 2026
Quality Inn & Suites Mayo Clinic Area
Breakfast served
Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN
3.0 star property
Downtown Rochester
8.8 out of 10, Excellent, (853)
Experience comfort in this downtown hotel with an indoor pool, hot tub, and 24-hour fitness center. Just 5 minutes from Mayo Clinic, the location draws praise from travelers. Rooms include refrigerators and microwaves, while the restaurant and bar offer welcome refreshment.
"Everything was wonderful! Helpful, friendly staff, great location, nice amenities."
United States
kristi
The price is AED 393
AED 453 total
includes taxes & fees
2 Jan - 3 January 2026
Hilton Garden Inn Rochester Downtown, MN
Exterior
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
3.0 star property
Kutzky Park
9.2 out of 10, Wonderful, (771)
"Clean room and housekeeping service was excellent"
United States
Dawn
The price is AED 309
AED 355 total
includes taxes & fees
28 Dec - 29 Dec
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
Indoor pool, open 9:00 AM to 10:00 PM, pool umbrellas, sun loungers
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
2.5 star property
Rochester
8.2 out of 10, Very Good, (794)
Situated just minutes from Mayo Clinic, this Rochester hotel offers an indoor pool and hot tub for relaxation after appointments. Enjoy free breakfast, WiFi, and parking, plus American dining at Wildwood Sports Bar. Nearby shops and restaurants enhance the stay.
"This hotel was"
United States
Sheila
The price is AED 328
AED 378 total
includes taxes & fees
2 Jan - 3 January 2026
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
Free daily full breakfast
Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area
2.0 star property
Rochester
9.0 out of 10, Wonderful, (899)
This quiet Rochester hotel offers a serene retreat with complimentary full breakfast and parking. Just minutes from Mayo Clinic campuses and convenient to area attractions. The 24-hour fitness center and helpful staff enhance your stay.
"Good breakfast..shuttle service is excellent..super nice staff.."
United States
DALE K
The price is AED 248
AED 286 total
includes taxes & fees
9 Jan - 10 January 2026
Econo Lodge Mayo Clinic Area
Exterior
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
2.5 star property
Kutzky Park
8.8 out of 10, Excellent, (765)
Minutes from Mayo Clinic and Saint Marys Campus, this hotel offers free breakfast, WiFi, and parking. Guests love the helpful staff. Jump into the indoor pool or hit the fitness center after exploring nearby Kutzky Park and Cascade Lake Beach.
"Clean room, friendly staff. The only minus is the lighting in the bathroom, way too dim. "
United States
Stacy
The price is AED 349
AED 402 total
includes taxes & fees
28 Dec - 29 Dec
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
Courtyard
EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG
4.0 star property
Kutzky Park
9.4 out of 10, Exceptional, (963)
Focused on well-being, this Rochester hotel is a 15-minute walk from Mayo Clinic campuses. Refresh in the indoor pool and hot tub, energize at the 24-hour fitness center, or relax at the bar after exploring nearby Plummer Building.
"Rooms are comfortable and staff was was so professional and helpful."
United States
William
The price is AED 340
AED 399 total
includes taxes & fees
26 Dec - 27 Dec
EVEN Hotel Rochester - Mayo Clinic Area by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Stay near popular Wykoff attractions

Ed's Museum

You can spend time exploring the galleries in Ed's Museum during your travels in Wykoff. Discover the countryside while you're in the area.
See properties

Top Wykoff Hotel Reviews

Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

10/10 Excellent
"Clean room, good room service and good breakfast."
Donald 2-night trip
Posted 3 days ago
Kahler Inn and Suites - Mayo Clinic Area

More cheap stays in Wykoff

Super 8 by Wyndham Rochester Mayo Clinic Area

Super 8 by Wyndham Rochester Mayo Clinic Area

106 SE 21st Street Rochester MN
The price is AED 187 per night from Jan 2 to Jan 3
AED 187
AED 216 total
2 Jan - 3 January 2026
includes taxes & fees
7.6/10 Good! (1,001 reviews)

Hotels in Wykoff with star-rating

Frequently asked questions

Where is the best place to stay in Wykoff?
Located 24 mi (38.6 km) from the heart of Wykoff, Kahler Grand Hotel is a top choice for your stay based on our traveler data. Other good choices for your stay in the area are Kahler Inn and Suites - Mayo Clinic Area and Med City Inn & Suites - Mayo Clinic Area. See all available top hotels, or vacation rentals in Wykoff.
What's the top vacation rental that Wykoff has to offer?
Meet Don - A Modern, Zero-step, Pet-friendly home in Rochester: Visitors like this Wykoff vacation home rental. It has air-conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a stovetop, and a microwave. See all vacation rentals in Wykoff.
If I need to cancel my hotel reservation in Wykoff, will I receive a refund?
Yes, most hotel room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you have a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Wykoff.
Where can I learn more about changing or cancelling my trip to Wykoff?
For more details about changing or cancelling your trip to Wykoff, click here.
What's the best hotel to stay with easy access to Ed's Museum?
Quiet, comfortable bed & breakfast in a gorgeous rural setting! is one of the top choices for your stay based on our traveler data, and this B&B offers free breakfast and private decks. You'll find it 5.5 mi (8.9 km) from Ed's Museum. Other good options around the area include Americas Best Value Inn & Suites Spring Valley and Oakenwald Terrace.
What is the best accommodation for staying close to Rochester International Airport (RST)?
AmericInn by Wyndham Rochester Airport is a popular hotel, featuring free breakfast and an indoor pool. It's located a short 0.6 mi (1 km) from Rochester Intl. Airport. Other choices near the airport include La Quinta Inn & Suites by Wyndham Rochester and Comfort Suites.
How is it staying in Wykoff?
Visitors can enjoy all that Wykoff has to offer including its museums. There are 319 hotels and other accommodations in the surrounding area. Find out more about Wykoff.
What are the top places to visit in Wykoff?
A favorite place to visit is Ed's Museum. You'll also find Forestville Mystery Cave State Park and Four Daughters Vineyard & Winery in the area. Check out what more to see and do in Expedia's Wykoff guide.
What's the weather like in Wykoff?
The hottest months are usually July and August with an average temp of 68°F, while the coldest months are January and February with an average of 22°F. The snowiest months in Wykoff are January, March, February, and April, with each month seeing an average of 8 inches of snowfall.

Explore a world of travel with Expedia