Does Clayton have any 4-star all-inclusive resorts?

Use our filters to look for all-inclusive Clayton resorts where your room, food, daily entertainment and more are provided for in the purchase price. Can't find anything available? You can also kick back and relax in sophisticated surroundings at other excellent 4-star stays in the city. The Cheshire and Le Méridien St. Louis Clayton are two popular options.

What are the top 4-star apartments in Clayton?

Prepare to enjoy Clayton like a local at one of our 4-star apartments. Featuring a garden and individually decorated rooms, Tower Grove Getaways By Namastay is a great pick in this amazing destination. Or spend your stay at Hickory B - 1 Bedroom Apts and make use of a fireplace and a deck.

What are the top 4-star hotels in downtown Clayton?

Stay at Le Méridien St. Louis Clayton and you'll be conveniently placed to experience the best of downtown Clayton. Located about 2 kilometers northwest from the city center, this 4-star hotel also comes with a swimming pool and a garden.

The Best 4 Star Hotels in Clayton, MO from AED 415

The illuminated Gateway Arch at night with a city skyline in the background.

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Our top choices for Clayton 4-star hotels

A lobby with a sofa, two armchairs, a coffee table, and a staircase.

1. Hyatt Regency St. Louis at The Arch

Downtown St. Louis

Tracy

AED 542 total

includes taxes & fees

25 Nov - 26 Nov

A bar area with high wooden ceilings, a large mural, and a variety of seating options including tables and bar stools.

2. 21C Museum Hotel St Louis

Downtown West

A.R.

AED 635 total

includes taxes & fees

22 Nov - 23 Nov

A buffet with fruits, pastries, and beverages.

3. Renaissance St. Louis Airport Hotel

Berkeley

Joy

AED 478 total

includes taxes & fees

20 Nov - 21 Nov

A rooftop restaurant with round tables, chairs, and a view of the city.

4. Moonrise Hotel

Delmar Loop

Jennifer

AED 650 total

includes taxes & fees

18 Nov - 19 Nov

A modern outdoor lounge area with seating, a bar, and a view of a cityscape.

5. Live by Loews - St.Louis

Downtown St. Louis

brandon

AED 607 total

includes taxes & fees

15 Nov - 16 Nov

An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.

6. Ameristar Casino Resort and Spa

St. Charles

Samuel

AED 655 total

includes taxes & fees

30 Nov - 1 Dec

A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.

7. The Royal Sonesta Chase Park Plaza St. Louis

Central West End

Sara

AED 689 total

includes taxes & fees

22 Nov - 23 Nov

A rooftop pool area with multiple lounge chairs and umbrellas, surrounded by a modern building with large windows.

8. Le Méridien St. Louis Clayton

Clayton

Marsha

AED 658 total

includes taxes & fees

15 Nov - 16 Nov

A modern hotel room with a large bed, a nightstand, a mirror, and a view of the city through arched windows.

9. The Westin St. Louis

Downtown St. Louis

Stacy

AED 563 total

includes taxes & fees

15 Nov - 16 Nov

A modern dining area with round tables, orange chairs, and a decorative wall with pottery.

10. Marriott St. Louis Airport

Edmundson

Ravyn

AED 630 total

includes taxes & fees

13 Nov - 14 Nov

A long bar with multiple tables and chairs, wooden floors, and ornate chandeliers.

11. River City Casino & Hotel

St. Louis

jodi

AED 429 total

includes taxes & fees

23 Nov - 24 Nov

A multi-story hotel with a prominent 'Marriott' sign, featuring a classic architectural style with a red brick facade and large windows.

12. Marriott St. Louis Grand

Downtown St. Louis

Leonor

AED 555 total

includes taxes & fees

22 Nov - 23 Nov

A bar area with a central bar, multiple stools, and a chandelier.

13. Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Downtown St. Louis

Anastasia

AED 415 total

includes taxes & fees

23 Nov - 24 Nov

A restaurant with round tables and chairs, a bar area, and a patterned ceiling.

14. Drury Plaza Hotel St. Louis Brentwood

Brentwood

Stacey Rochelle

AED 558 total

includes taxes & fees

22 Nov - 23 Nov

A cozy lounge area with leather sofas, a fireplace, and a bar counter.

15. The Cheshire

Richmond Heights

Matthew

AED 647 total

includes taxes & fees

15 Nov - 16 Nov

A multi-story hotel with a prominent corner location, large windows, and a well-lit facade.

16. Embassy Suites by Hilton St. Louis Downtown

Downtown St. Louis

Megan

AED 498 total

includes taxes & fees

23 Nov - 24 Nov

A rooftop terrace with outdoor seating, string lights, and a city skyline view.

17. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Grand Center

Skylee

AED 448 total

includes taxes & fees

22 Nov - 23 Nov

A modern lounge area with a central fire feature, seating, and large windows offering a city view.

18. Hilton St. Louis at the Ballpark

Downtown St. Louis

Kella

AED 605 total

includes taxes & fees

22 Nov - 23 Nov

A spacious lobby with high arched ceilings, ornate columns, and a central fountain.

19. St. Louis Union Station Hotel, Curio Collection by Hilton

Downtown West

Donna

AED 677 total

includes taxes & fees

22 Nov - 23 Nov

A spacious lobby with modern seating arrangements, a large chandelier, and a view of the cityscape through large windows.

20. Hilton Pennywell St. Louis at the Arch

Downtown St. Louis

Tabitha

AED 471 total

includes taxes & fees

15 Nov - 16 Nov

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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Clayton.

Four Seasons Hotel St Louis

999 North Second Street St. Louis MO

AED 1,377

AED 1,611 total

1 Nov - 2 Nov

includes taxes & fees

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Pool Spa Hot tub Breakfast included Waterpark

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Clayton Hotel Reviews

Live by Loews - St.Louis

8/10 Good

"The property is immaculate. The staff is warm and welcoming. The rooms are beautifully designed could be a bit more spacious. The weird thing which maybe I’m just out of touch but there was no microwave in the room and if I understood correctly there is a nightly fee to have one brought to your room. Other than that I enjoyed my stay and now that I’m aware of the amenities I would be prepared in the future"

Moonrise Hotel

10/10 Excellent

"Stayed for a long weekend in October. Front desk staff (shout out Antoine and Duwan!) Were friendly and welcoming. Gave great recs for food and activities. Room was clean and well-stocked. Beds were 8/10 comfy but after a long day exploring I still got 10/10 rest. Location is central to so much STL has to offer and easy for rideshare pickup. Definitely get a drink on the rooftop during your stay!"

Frequently asked questions

What are the best 4-star hotels in Clayton?

Kick back and unwind in 4-star hotel comfort at Le Méridien St. Louis Clayton. Rated highly by many of our guests, it offers concierge services and premium bedding. Also check out The Cheshire. Egyptian-cotton sheets and a terrace help make this escape another popular choice in Clayton.

How much does it cost to stay in a 4-star hotel in Clayton?

With Expedia's search and sort filters, locking in a superb deal on a 4-star hotel in Clayton just got easier. Start by entering your chosen travel dates and length of your stay. Then sort the results by price and pick the option that best fits your style and budget.

Search for the lowest price from AED 1,611

What's the difference between 5-star and 4-star hotels in Clayton?

If you choose to vacation at a 4-star hotel in Clayton, you'll usually find loads of conveniences to ensure you're comfortable, such as a restaurant, pool and gym. You can look forward to high-quality service and upscale surroundings. Go for a 5-star hotel and you'll get a few extra bells and whistles — think on-site spas, 24-hour front desk and opulent turndown services. You're likely to get extra amenities and premium services at a 5-star retreat, but both are awesome options for luxury guests.

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Check availability on Clayton 4 Star Hotels

Our top choices for Clayton 4-star hotels

1. Hyatt Regency St. Louis at The Arch

2. 21C Museum Hotel St Louis

3. Renaissance St. Louis Airport Hotel

4. Moonrise Hotel

5. Live by Loews - St.Louis

6. Ameristar Casino Resort and Spa

7. The Royal Sonesta Chase Park Plaza St. Louis

8. Le Méridien St. Louis Clayton

9. The Westin St. Louis

10. Marriott St. Louis Airport

11. River City Casino & Hotel

12. Marriott St. Louis Grand

13. Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

14. Drury Plaza Hotel St. Louis Brentwood

15. The Cheshire

16. Embassy Suites by Hilton St. Louis Downtown

17. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

18. Hilton St. Louis at the Ballpark

19. St. Louis Union Station Hotel, Curio Collection by Hilton

20. Hilton Pennywell St. Louis at the Arch

Explore similar 5-star hotels

Four Seasons Hotel St Louis

The Ritz-Carlton, St. Louis

Top Clayton Hotel Reviews

Live by Loews - St.Louis

Moonrise Hotel

Hyatt Regency St. Louis at The Arch

Le Méridien St. Louis Clayton

Frequently asked questions

Find 4 Star Hotels in Clayton, MO from AED 415

Change your mind

Treat yourself

Be picky

Check availability on Clayton 4 Star Hotels

Our top choices for Clayton 4-star hotels

1. Hyatt Regency St. Louis at The Arch

2. 21C Museum Hotel St Louis

3. Renaissance St. Louis Airport Hotel

4. Moonrise Hotel

5. Live by Loews - St.Louis

6. Ameristar Casino Resort and Spa

7. The Royal Sonesta Chase Park Plaza St. Louis

8. Le Méridien St. Louis Clayton

9. The Westin St. Louis

10. Marriott St. Louis Airport

11. River City Casino & Hotel

12. Marriott St. Louis Grand

13. Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

14. Drury Plaza Hotel St. Louis Brentwood

15. The Cheshire

16. Embassy Suites by Hilton St. Louis Downtown

17. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

18. Hilton St. Louis at the Ballpark

19. St. Louis Union Station Hotel, Curio Collection by Hilton

20. Hilton Pennywell St. Louis at the Arch

Explore similar 5-star hotels

Four Seasons Hotel St Louis

Top Clayton Hotel Reviews

Live by Loews - St.Louis

Frequently asked questions