Find 4 Star Hotels in Defiance, MO from AED 496
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Our top choices for Defiance 4-star hotels
8.8 out of 10, Excellent, (1,000 reviews)
"Great room, great amenities!"
Linda or James
The price is AED 479
AED 558 total
includes taxes & fees
25 Jan - 26 Jan
8.4 out of 10, Very Good, (1,006 reviews)
"Was an amazing hotel to stay at!! Clean spacious and very nice!!! Will stay here again!!"
Darci
The price is AED 658
AED 830 total
includes taxes & fees
19 Jan - 20 Jan
8.2 out of 10, Very Good, (1,002 reviews)
"Stayed one night felt very safe here"
William
The price is AED 428
AED 496 total
includes taxes & fees
23 Jan - 24 Jan
DoubleTree by Hilton Hotel St. Louis - Chesterfield
DoubleTree by Hilton Hotel St. Louis - ChesterfieldChesterfield
8.6 out of 10, Excellent, (1,000 reviews)
"Great hotel!"
John
The price is AED 449
AED 521 total
includes taxes & fees
6 Feb - 7 Feb
8.8 out of 10, Excellent, (134 reviews)
"It was very nice. A great place to stay in a great little town."
Hal
The price is AED 461
AED 525 total
includes taxes & fees
15 Feb - 16 Feb
Historic Main Street Heritage Retreat
Historic Main Street Heritage RetreatSt. Charles Historic District
9.4 out of 10, Exceptional, (40 reviews)
"No complaints here, would definitely stay here again! "
Adrienne R.
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Learn more about Defiance
Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighboring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.
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Stay near popular Defiance attractions
- Hotels near Chandler Hill Vineyards
- Hotels near Historic Daniel Boone Home and Heritage Center
- Hotels near August A. Busch Memorial Conservation Area
- Hotels near Sugar Creek Winery
- Hotels near Yellow Farmhouse Winery
- Hotels near Broemmelsiek Park
- Hotels near Six Flags St. Louis
- Hotels near Ameristar Casino St. Charles
- Hotels near Mississippi River
- Hotels near Hollywood Casino Amphitheatre
- Hotels near St Charles Convention Center
- Hotels near Westport Plaza
- Hotels near Purina Farms
- Hotels near Hidden Valley Ski Resort
- Hotels near Magic House - St. Louis Children's Museum
- Hotels near Route 66 State Park
- Hotels near Lindenwood University
- Hotels near Hollywood Casino
- Hotels near Missouri River
- Hotels near Family Arena
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Explore more hotels
- Drury Inn & Suites Southwest St. Louis
- Hampton Inn St. Charles St. Peters
- The St. Charles Guest House, lovely historic home, fun for families and groups
- Drury Plaza Hotel St. Louis St. Charles
- Comfort Suites St Charles - St Louis
- Embassy Suites by Hilton St. Louis St. Charles
- Crowne Plaza St. Louis Airport by IHG
- Wingate by Wyndham St. Louis/Fenton Route 66
- Drury Inn & Suites St. Louis St. Peters
- Days Inn and Suites by Wyndham St. Louis/Westport Plaza
- Drury Plaza Hotel St. Louis Chesterfield
- Hampton Inn & Suites St. Charles Old Town Area
- Best Western Plus St. Louis West-Westport
- Hyatt Place St. Louis/Chesterfield
- Drury Plaza Hotel St. Louis Creve Coeur
- Fairfield Inn & Suites by Marriott St. Louis Chesterfield
- Hilton St. Louis Frontenac
- Holiday Inn Express & Suites St. Louis - Chesterfield by IHG
- Extended Stay America Suites St Louis St Peters
- DoubleTree by Hilton St. Louis - Westport