A sunset over a mountainous landscape with scattered clouds.

Find 4 Star Hotels in La Mesa, CA from AED 545

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on La Mesa 4 Star Hotels

This weekend
Next weekend

Our top choices for La Mesa 4-star hotels

Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
Downtown San Diego
8.4 out of 10, Very Good, (6,235 reviews)
"Great place to stay if visiting san diego recommend"
United States
Carlos
The price is AED 559
AED 776 total
includes taxes & fees
6 Jul - 7 Jul
Wyndham San Diego Bayside

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego
4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (3,924 reviews)
"Great stay overall!"
United States
Keanna
The price is AED 619
AED 894 total
includes taxes & fees
19 Jul - 20 Jul
Hard Rock Hotel San Diego

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego
4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (2,770 reviews)
"A beautiful property i. a great location"
United States
Marcia
The price is AED 1,098
AED 1,473 total
includes taxes & fees
8 Jul - 9 Jul
Manchester Grand Hyatt San Diego

Paradise Point Resort & Spa

Paradise Point Resort & Spa
4.0 star property
Mission Bay
8.8 out of 10, Excellent, (2,696 reviews)
"This was a beautiful place to stay. Right by the water, staff was very helpful, restaurant's were good"
United States
Myesha
The price is AED 1,084
AED 1,441 total
includes taxes & fees
6 Jul - 7 Jul
Paradise Point Resort & Spa

Loews Coronado Bay Resort

Loews Coronado Bay Resort
4.0 star property
Silver Strand
9.0 out of 10, Wonderful, (1,088 reviews)
"Really nice hotel with great views"
United States
Fernando
The price is AED 1,027
AED 1,323 total
includes taxes & fees
2 Aug - 3 Aug
Loews Coronado Bay Resort

Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina
4.0 star property
Mission Bay
8.6 out of 10, Excellent, (1,628 reviews)
"Amazing place!"
United States
Yesenia
The price is AED 988
AED 1,330 total
includes taxes & fees
6 Jul - 7 Jul
Hyatt Regency Mission Bay Spa and Marina

Lafayette Hotel & Club

Lafayette Hotel & Club
4.0 star property
University Heights
9.4 out of 10, Exceptional, (1,773 reviews)
"Beautiful hotel"
United States
Cuauhtemoc
The price is AED 951
AED 1,093 total
includes taxes & fees
6 Jul - 7 Jul
Lafayette Hotel & Club

Town and Country San Diego

Town and Country San Diego
4.0 star property
Mission Valley
8.6 out of 10, Excellent, (1,601 reviews)
"Excellent resorts"
United States
christian
The price is AED 856
AED 1,111 total
includes taxes & fees
3 Aug - 4 Aug
Town and Country San Diego

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
Harbor Island
8.4 out of 10, Very Good, (3,529 reviews)
"Great location and shuttle service to and from the airport."
Canada
Malinda
The price is AED 621
AED 899 total
includes taxes & fees
5 Jul - 6 Jul
Sheraton San Diego Resort

Hilton San Diego Bayfront

Hilton San Diego Bayfront
4.0 star property
Downtown San Diego
8.6 out of 10, Excellent, (2,188 reviews)
"The rooms were very clean and the view was beautiful!"
United States
Makaya
The price is AED 729
AED 1,025 total
includes taxes & fees
19 Jul - 20 Jul
Hilton San Diego Bayfront

Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy
4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (766 reviews)
"Great location to"
United States
Nestor
The price is AED 639
AED 741 total
includes taxes & fees
5 Jul - 6 Jul
Courtyard by Marriott San Diego Downtown Little Italy

Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark
4.0 star property
Downtown San Diego
9.2 out of 10, Wonderful, (2,262 reviews)
"Wonderful stay"
United States
Stephanie
The price is AED 570
AED 827 total
includes taxes & fees
5 Jul - 6 Jul
Omni San Diego Hotel at the Ballpark

San Diego Mission Bay Resort

San Diego Mission Bay Resort
4.0 star property
Mission Bay
8.6 out of 10, Excellent, (1,500 reviews)
"We have stayed here before, good location, clean rooms, great staff."
United States
Lance
The price is AED 1,098
AED 1,457 total
includes taxes & fees
6 Jul - 7 Jul
San Diego Mission Bay Resort

Rancho Bernardo Inn

Rancho Bernardo Inn
4.0 star property
Rancho Bernardo
8.8 out of 10, Excellent, (1,000 reviews)
"This property was the perfect getaway. Service was amazing, food was great, and the views were incredible. This is a great hidden gem!"
United States
Marissa
The price is AED 846
AED 1,133 total
includes taxes & fees
6 Jul - 7 Jul
Rancho Bernardo Inn

The Westin San Diego Gaslamp Quarter

The Westin San Diego Gaslamp Quarter
4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (1,000 reviews)
"Location of the Hotel is great for restaurants "
United States
Aruny
The price is AED 731
AED 955 total
includes taxes & fees
5 Jul - 6 Jul
The Westin San Diego Gaslamp Quarter

San Diego Marriott Gaslamp Quarter

San Diego Marriott Gaslamp Quarter
4.0 star property
Downtown San Diego
8.8 out of 10, Excellent, (1,686 reviews)
"Great place"
United States
Jorge
The price is AED 590
AED 684 total
includes taxes & fees
5 Jul - 6 Jul
San Diego Marriott Gaslamp Quarter

Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
El Cajon
9.4 out of 10, Exceptional, (1,993 reviews)
"Always a great stay"
United States
Jeanette
The price is AED 456
AED 545 total
includes taxes & fees
12 Jul - 13 Jul
Sycuan Casino Resort

DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley
4.0 star property
Mission Valley
8.4 out of 10, Very Good, (1,714 reviews)
"A great place to stay many things to see and do"
United States
Mauricio
The price is AED 599
AED 689 total
includes taxes & fees
19 Jul - 20 Jul
DoubleTree by Hilton Hotel San Diego - Mission Valley

Catamaran Resort and Spa

Catamaran Resort and Spa
4.0 star property
Mission Beach
8.6 out of 10, Excellent, (1,287 reviews)
"Great property for families!"
United States
Claudine
The price is AED 996
AED 1,340 total
includes taxes & fees
6 Jul - 7 Jul
Catamaran Resort and Spa

Hotel del Coronado, Curio Collection by Hilton

Hotel del Coronado, Curio Collection by Hilton
4.0 star property
Historic Downtown Coronado
8.8 out of 10, Excellent, (1,002 reviews)
"Beautiful- a must stay property!"
United States
Julie Haff
The price is AED 2,026
AED 2,453 total
includes taxes & fees
21 Jul - 22 Jul
Hotel del Coronado, Curio Collection by Hilton
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in La Mesa.
Still don't see what you're looking for?
See all properties in La Mesa.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about La Mesa

Nestled between rolling hills, this charming suburb offers hiking trails through Mission Trails Park and Lake Murray's scenic waterfront paths. Visit the vibrant farmers market on Fridays, then explore the antique shops and local breweries along La Mesa Boulevard's historic district.

A sunset over a mountainous landscape with scattered clouds.

Top La Mesa Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in La Mesa?
San Diego Marriott Mission Valley is a 4-star hotel in La Mesa that's popular among Expedia guests. A swimming pool and premium bedding are a couple of its amenities. Travelers also love Sheraton Mission Valley San Diego Hotel. From room service to premium bedding, it features conveniences that cater to every aspect of your enjoyment and relaxation.
How much does it cost to stay in a 4-star hotel in La Mesa?
With Expedia's search and sort filters, landing a great deal on a 4-star hotel in La Mesa just got simpler. Start by keying in your chosen arrival date and length of your break. Then list the results by price and choose a hotel that best fits your style and budget.

  • Search for the lowest price from AED 833

What's the difference between 5-star and 4-star hotels in La Mesa?
Treat yourself to luxury living during your La Mesa vacation by choosing a 4-star hotel. As well as featuring upmarket surroundings, these properties are usually packed with amenities, including complimentary bathrobes, large beds and more. A 5-star hotel will go the extra mile to make your stay an even more lavish and special one. 24-hour concierge assistance, elegant décor and world-class dining are only the start of the superior services and conveniences you'll likely be able to enjoy.