Find 4 Star Hotels in Southern Indiana from AED 356

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Southern Indiana 4 Star Hotels

Tonight
6 May - 7 May
Tomorrow
7 May - 8 May
This weekend
8 May - 10 May
Next weekend
15 May - 17 May

Our top choices for Southern Indiana 4-star hotels

4 restaurants, breakfast, lunch, dinner served; American cuisine

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (4,210 reviews)
"Loved our stay!"
United States
Phil
The price is AED 580
AED 682 total
includes taxes & fees
23 May - 24 May
Galt House Hotel Trademark Collection by Wyndham
3 bars/lounges, cocktail bar, lobby lounge

Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1,871 reviews)
"Great place to stay, perfect location "
United States
Ben
The price is AED 915
AED 1,076 total
includes taxes & fees
9 May - 10 May
Omni Louisville Hotel
Lobby

The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,190 reviews)
"Beautiful historic hotel! Room was beautifully decorated and the restaurant and dinner were amazing!"
United States
Richard
The price is AED 567
AED 667 total
includes taxes & fees
27 May - 28 May
The Brown Hotel
Reception

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1,211 reviews)
"Great location "
United States
Ruben
The price is AED 481
AED 566 total
includes taxes & fees
25 May - 26 May
Embassy Suites Louisville Downtown
Exterior

Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1,005 reviews)
"Perfect location "
United States
Kelly
The price is AED 621
AED 731 total
includes taxes & fees
24 May - 25 May
Louisville Marriott Downtown
Lobby

Hyatt Regency Louisville

Hyatt Regency Louisville
4.0 star property
Downtown Louisville
8.8 out of 10, Excellent, (1,005 reviews)
"Great hotel close to the heart of Louisville. "
United States
Collin
The price is AED 446
AED 525 total
includes taxes & fees
23 May - 24 May
Hyatt Regency Louisville
Terrace/patio

Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1,084 reviews)
"This hotel is in such a great location and is within walking distance to multiple coffee shops, restaurants, antique stores, boutiques, bars, etc! Super clean and the staff was so helpful and friendly. "
United States
Emily
The price is AED 496
AED 583 total
includes taxes & fees
17 May - 18 May
Hotel Genevieve part of JdV by Hyatt
Terrace/patio

Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
Downtown Louisville
9.6 out of 10, Exceptional, (465 reviews)
"Bar and restaurant were amazing!!"
Canada
Cheryl
The price is AED 643
AED 757 total
includes taxes & fees
25 May - 26 May
Hotel Distil, Autograph Collection
Front of property

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,002 reviews)
"Unique venue with some many amenities. Staff are super helpful and hospital. Will stay again when I’m in town."
United States
Jason
The price is AED 559
AED 676 total
includes taxes & fees
26 May - 27 May
21c Museum Hotel Louisville
Lobby

The Grady

The Grady
4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,001 reviews)
"Lovely place, beautiful decor, walking distance to local bars and restaurants."
United States
Aimee
The price is AED 576
AED 677 total
includes taxes & fees
24 May - 25 May
The Grady
Terrace/patio

Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (103 reviews)
"Valet was incredibly kind and efficient, hotel staff were all engaging and helpful. Great location, clean room, easy access. Walking distance to food & nightlife!"
United States
Lori
The price is AED 720
AED 847 total
includes taxes & fees
24 May - 25 May
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Lobby

DoubleTree by Hilton Evansville

DoubleTree by Hilton Evansville
4.0 star property
Downtown Evansville
8.6 out of 10, Excellent, (1,002 reviews)
"Great location…nice rooms"
United States
Steven
The price is AED 358
AED 412 total
includes taxes & fees
17 May - 18 May
DoubleTree by Hilton Evansville
Exterior

Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
4.0 star property
Downtown Louisville
8.6 out of 10, Excellent, (1,004 reviews)
"It was beautiful, staff was friendly, room was clean, mattress and pillows were very comfy."
United States
Angela
The price is AED 528
AED 621 total
includes taxes & fees
24 May - 25 May
Seelbach Hilton Louisville Downtown
Lounge

Stellar Suites

Stellar Suites
4.5 star property
Downtown Louisville
9.6 out of 10, Exceptional, (132 reviews)
"Easy check in and check out process and very convenient location."
United States
Richard
The price is AED 405
AED 662 total
includes taxes & fees
10 May - 11 May
Stellar Suites
Property entrance

The Pepin Mansion Historic B&B

The Pepin Mansion Historic B&B
4.0 star property
New Albany
9.8 out of 10, Exceptional, (685 reviews)
"Absolutely a beautiful comfy place to stay."
United States
Susan
The price is AED 315
AED 356 total
includes taxes & fees
10 May - 11 May
The Pepin Mansion Historic B&B
Exterior

stayAPT Suites Louisville North-Clarksville

stayAPT Suites Louisville North-Clarksville
4.0 star property
Clarksville
9.8 out of 10, Exceptional, (47 reviews)
"Our first time staying here and we were very happy. Stayed 3 nights and it was so quiet and clean, close to everything. Love the kitchen and soft bed. We arrived late but was able to get into my room via the stayAPT app even tho I booked on Expedia. The manager was so nice and checked on us the next day too. I’d stay here again any day! "
United States
Sarah
stayAPT Suites Louisville North-Clarksville
Seasonal outdoor pool

CozySuites at Nulu

CozySuites at Nulu
4.0 star property
Downtown Louisville
7.8 out of 10, Good, (28 reviews)
"Wonderful stay - great spot and lots of great dining options and bars nearby "
United States
Roy
The price is AED 283
AED 755 total
includes taxes & fees
27 May - 28 May
CozySuites at Nulu
32-inch Smart TV with cable channels

The Reserve on Main

The Reserve on Main
4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (3 reviews)
"The room was great and clean. Great location. "
United States
De'Carlon
The Reserve on Main
Exterior

Bourbon Barrel Inn Bed & Breakfast

Bourbon Barrel Inn Bed & Breakfast
4.0 star property
Old Louisville
10.0 out of 10, Exceptional, (4 reviews)
"Inn Keepers were wonderful. "
United States
jonathan
Bourbon Barrel Inn Bed & Breakfast
Family House, Multiple Beds | Private kitchen | Fridge, microwave, oven, stovetop

Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb

Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
4.0 star property
Sellersburg
9.4 out of 10, Exceptional, (10 reviews)
"Very nice house in a nice neighborhood, spacious home environmental, felt more that at home there,"
United States
Tammy
Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Learn more about Southern Indiana

Live music, casinos, and sights from Patoka Lake Swimming Beach to Patoka Lake—discover it all in Southern Indiana.

See all hotels in Southern Indiana

Top Southern Indiana Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in Southern Indiana?
If your Southern Indiana vacation leads you to Louisville, consider Galt House Hotel Trademark Collection by Wyndham. With lots of amenities such as massage services and a swimming pool, it scores top marks from many Expedia customers. Another popular pick here is Hyatt Regency Louisville. It also has 4 stars and offers designer toiletries and a swimming pool.
How much does it cost to stay in a 4-star hotel in Southern Indiana?
To book a 4-star hotel in Southern Indiana that's within your budget, take advantage of Expedia's handy filters. Take a look at what's available during your preferred dates and use our pricing filter to set your limit. You can also sort your results by the most budget-friendly option first.

  • Search for the lowest price from AED 356

What's the difference between 5-star and 4-star hotels in Southern Indiana?
Give yourself the luxury treatment during your Southern Indiana escape by checking in to a 4-star hotel. As well as featuring upmarket surroundings, these properties are typically packed with amenities such as large beds, bathrobes and plenty more. A 5-star hotel will go the extra mile to make your stay an even more indulgent and memorable one. 24-hour concierge assistance, luxurious spas and world-class dining are a few of the exclusive services and conveniences you'll likely be able to enjoy.

Explore a world of travel with Expedia