A modern glass building with a curved facade and a sign reading "The Kentucky Center".

Find 4 Star Hotels in Southern Indiana from AED 427

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Check availability on Southern Indiana 4 Star Hotels

Next weekend
13 Nov - 15 Nov
In two weeks
20 Nov - 22 Nov

Our top choices for Southern Indiana 4-star hotels

A balcony with a view of a river, a bridge, and a cityscape.

1. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (4,473 reviews)
"Great place to stay!!!"
United States
Shun
The price is AED 500
AED 588 total
includes taxes & fees
22 Nov - 23 Nov
Galt House Hotel Trademark Collection by Wyndham
A grand lobby with ornate columns, plush seating, and a chandelier.

2. The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,467 reviews)
"Beautiful hotel!"
United States
Brianne
The price is AED 383
AED 451 total
includes taxes & fees
25 Nov - 26 Nov
The Brown Hotel
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.

3. Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (2,223 reviews)
"Nice location"
United States
Brian
The price is AED 746
AED 878 total
includes taxes & fees
16 Nov - 17 Nov
Omni Louisville Hotel
A spacious lobby with a bar area, seating arrangements, and a visible kitchen bar.

4. Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1,002 reviews)
"Great place"
United States
MILTON
The price is AED 616
AED 725 total
includes taxes & fees
22 Nov - 23 Nov
Louisville Marriott Downtown
A spacious lobby with a central escalator, seating areas, and modern lighting.

5. Hyatt Regency Louisville

Hyatt Regency Louisville
4.0 star property
Downtown Louisville
8.8 out of 10, Excellent, (1,000 reviews)
"amazing location will definitely be back"
United States
Michael Jered
The price is AED 459
AED 540 total
includes taxes & fees
23 Nov - 24 Nov
Hyatt Regency Louisville
A spacious lobby with a blue sofa, a wooden coffee table, and a chandelier.

6. Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville
9.0 out of 10, Wonderful, (1,390 reviews)
"Great room, excellent staff, exceptional breakfast, very clean."
United States
Chase
The price is AED 449
AED 528 total
includes taxes & fees
23 Nov - 24 Nov
Embassy Suites Louisville Downtown
A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.

7. The Grady

The Grady
4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,007 reviews)
"Our stay at The Grady was exceptional and we will definitely be back to stay again soon!!"
United States
Greg
The price is AED 521
AED 613 total
includes taxes & fees
24 Nov - 25 Nov
The Grady
A cozy room with a geometric-patterned ceiling, a sofa, and a chair.

8. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,002 reviews)
"Nice modern rooms and excellent cocktails in the bar."
United States
Erick
The price is AED 559
AED 676 total
includes taxes & fees
29 Nov - 30 Nov
21c Museum Hotel Louisville
A multi-story hotel with a classic facade, large windows, and a modern glass building adjacent to it.

9. Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
Downtown Louisville
9.6 out of 10, Exceptional, (519 reviews)
"Excellent location and room!"
United States
Athina
The price is AED 740
AED 871 total
includes taxes & fees
22 Nov - 23 Nov
Hotel Distil, Autograph Collection
An outdoor dining area with a long table and wicker chairs, overhead lighting, and a view of the city.

10. Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
4.0 star property
Downtown Louisville
9.2 out of 10, Wonderful, (1,088 reviews)
"We’ve stayed here a number of times and we love it. Right in the middle of NuLu, it’s the perfect spot."
United States
Jesse
The price is AED 526
AED 618 total
includes taxes & fees
15 Nov - 16 Nov
Hotel Genevieve part of JdV by Hyatt
A hotel with a prominent sign, a central courtyard with a sculpture, and a dome structure in the background.

11. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
Downtown Louisville
9.4 out of 10, Exceptional, (177 reviews)
"Very good breakfast in hotel lobby restaurant. Extremely nice servers. Reasonably priced."
United States
Paul
The price is AED 479
AED 563 total
includes taxes & fees
23 Nov - 24 Nov
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
A modern building with a prominent sculpture in front, large glass windows, and a brightly lit entrance.

12. DoubleTree by Hilton Evansville

DoubleTree by Hilton Evansville
4.0 star property
Downtown Evansville
8.4 out of 10, Very good, (1,000 reviews)
"Check- in was super easy and seamless, even more so with the early check-in. The receptionist was very nice and helpful giving us information on places to visit; welcome cookies are so yummy. Such a great start to the stay!"
United States
Aleli Rodriguez
The price is AED 372
AED 427 total
includes taxes & fees
6 Dec - 7 Dec
DoubleTree by Hilton Evansville
A historic hotel with ornate architecture, a grand entrance, and a red carpet leading to the doors.

13. Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
4.0 star property
Downtown Louisville
8.8 out of 10, Excellent, (1,000 reviews)
"Very good hotel, a lot of history on it"
United States
Leonardo
The price is AED 524
AED 616 total
includes taxes & fees
27 Nov - 28 Nov
Seelbach Hilton Louisville Downtown
A modern building with a sign reading "Stellar Suites" and a crescent moon logo.

14. Stellar Suites

Stellar Suites
4.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (158 reviews)
"Location was great near meant restaurants and nightspots"
United States
Kevin
The price is AED 400
AED 657 total
includes taxes & fees
19 Nov - 20 Nov
Stellar Suites
A grand entrance with a staircase leading to a door, flanked by two lamp posts and a bench.

15. The Pepin Mansion Historic B&B

The Pepin Mansion Historic B&B
4.0 star property
New Albany
9.8 out of 10, Exceptional, (743 reviews)
"Wonderful and unique property with an outstanding breakfast."
United States
David
The price is AED 398
AED 449 total
includes taxes & fees
10 Nov - 11 Nov
The Pepin Mansion Historic B&B
A rooftop pool area with multiple lounge chairs and umbrellas, surrounded by a high-rise building with balconies.

16. CozySuites at Nulu

CozySuites at Nulu
4.0 star property
Downtown Louisville
7.6 out of 10, Good, (37 reviews)
"We love staying at this location when we come to Louisville. It’s a great apartment that is conveniently located. Love the view of the Big Four Bridge at night!"
United States
Jennifer
The price is AED 345
AED 827 total
includes taxes & fees
9 Nov - 10 Nov
CozySuites at Nulu
A modern hotel with a 'Stay Apt Suites' sign, featuring a brick facade, large windows, and a parking lot.

17. stayAPT Suites Louisville North-Clarksville

stayAPT Suites Louisville North-Clarksville
4.0 star property
Clarksville
9.8 out of 10, Exceptional, (59 reviews)
"Great option for a long term stay, good area many businesses in walking distance!"
Canada
Darlene
The price is AED 417
AED 471 total
includes taxes & fees
20 Nov - 21 Nov
stayAPT Suites Louisville North-Clarksville
A modern lounge with leather sofas, a coffee table, and a view of a classical building.

18. The Reserve on Main

The Reserve on Main
4.0 star property
Downtown Louisville
9.6 out of 10, Exceptional, (8 reviews)
"The room was great and clean. Great location. "
United States
De'Carlon
The Reserve on Main
A large, red brick Victorian-style building with a prominent tower, a flag, and a well-maintained front yard.

19. Bourbon Barrel Inn Bed & Breakfast

Bourbon Barrel Inn Bed & Breakfast
4.0 star property
Old Louisville
10.0 out of 10, Exceptional, (5 reviews)
"Inn Keepers were wonderful. "
United States
jonathan
Bourbon Barrel Inn Bed & Breakfast
A modern kitchen with wooden cabinets, a black microwave, and a stainless steel refrigerator.

20. Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb

Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
4.0 star property
Sellersburg
9.4 out of 10, Exceptional, (10 reviews)
"Very nice house in a nice neighborhood, spacious home environmental, felt more that at home there,"
United States
Tammy
Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
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Learn more about Southern Indiana

Live music, casinos, and sights from Patoka Lake Swimming Beach to Patoka Lake—discover it all in Southern Indiana.

See all hotels in Southern Indiana
A riverboat with multiple decks and passengers, docked near a bridge.

Top Southern Indiana Hotel Reviews

DoubleTree by Hilton Evansville

DoubleTree by Hilton Evansville

10/10 Excellent
"It was a very clean & comfortable stay . And enjoyed the restaurant & bar while we were there . Would definitely stay again ."
SueAnn 1-night trip
Posted 10 days ago
DoubleTree by Hilton Evansville

Frequently asked questions

What are the best 4-star hotels in Southern Indiana?
If your Southern Indiana vacation leads you to Louisville, consider Galt House Hotel Trademark Collection by Wyndham. With lots of amenities such as massage services and a swimming pool, it scores top marks from many Expedia customers. Another popular pick here is Hyatt Regency Louisville. It also has 4 stars and offers designer toiletries and a swimming pool.
How much does it cost to stay in a 4-star hotel in Southern Indiana?
To book a 4-star hotel in Southern Indiana that's within your budget, take advantage of Expedia's handy filters. Take a look at what's available during your preferred dates and use our pricing filter to set your limit. You can also sort your results by the most budget-friendly option first.

  • Search for the lowest price from AED 427

What's the difference between 5-star and 4-star hotels in Southern Indiana?
Give yourself the luxury treatment during your Southern Indiana escape by checking in to a 4-star hotel. As well as featuring upmarket surroundings, these properties are typically packed with amenities such as large beds, bathrobes and plenty more. A 5-star hotel will go the extra mile to make your stay an even more indulgent and memorable one. 24-hour concierge assistance, luxurious spas and world-class dining are a few of the exclusive services and conveniences you'll likely be able to enjoy.