Find 5 Star Hotels in East Prairie, MO

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Learn more about East Prairie

Discover local heritage at the East Prairie Historical Museum, where artifacts tell the story of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing.

Bridge over Mississippi River, New Orleans in background

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Frequently asked questions

How much does it cost to stay in a 5-star hotel in East Prairie?
There are several pricing options for 5-star hotels in East Prairie on Expedia. The amount you pay will depend on when you travel, length of your trip and other factors. Compare available properties for your preferred dates and make use of our pricing and other filters to score the ideal luxury stay.

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What makes a hotel 5 stars in East Prairie?
Impeccable guest service is the foundation of every 5-star hotel in East Prairie. From the minute you arrive, staff cater to your every need, whether arranging valet parking or providing a turn-down service. On top of that, hotels have to offer upscale amenities to be considered for a 5-star rating. These can include luxury toiletries, on-site spa facilities, pools, fine dining kitchens and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in East Prairie?
Find an indulgent stay that includes your lodging, meals, bar and entertainment in East Prairie with our handy filter tool. Search for hotels rated 5 stars and click on the "All inclusive" filter. Double-check what's included in the purchase price. This way, you can take full advantage of all the perks on offer when you arrive.