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Find 5 Star Hotels in Southeast Missouri, MO from AED 431

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Check availability on Southeast Missouri 5 Star Hotels

Tonight
30 Aug - 31 Aug
Tomorrow
31 Aug - 1 Sep
Next weekend
4 Sep - 6 Sep
In two weeks
11 Sep - 13 Sep
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Southeast Missouri.
The Riverview

The Riverview

777 Main St Cape Girardeau MO
AED 382
AED 431 total
1 Sep - 2 Sep
includes taxes & fees
The Riverview
Urban Lofts

Urban Lofts

104 North Jackson Street Perryville MO
Get ratesUrban Lofts
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Southeast Missouri

Explore the family-friendly area of Southeast Missouri—restaurants, wineries, and sights from K Bridge Recreation Area to Clearwater Lake.

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A historical marker sign for the Frisco Depot, detailing its construction in 1928, architectural style, and historical significance.
Photo by Bill Dillard

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Frequently asked questions

How much does it cost to stay in a 5-star hotel in Southeast Missouri?
How much you pay for a 5-star hotel in Southeast Missouri depends on factors like when you want to go and the length of your trip. A top tip for scoring the best deal? Use our pricing filters to check out all of the available accommodations for your preferred dates.
  • Search for the lowest price per night from AED 431
What makes a hotel 5 stars in Southeast Missouri?
Flawless guest service is at the heart of every 5-star hotel in Southeast Missouri. From the minute you step through the door, staff are at your beck and call, whether recommending activities and tours or providing in-room beauty treatments. Additionally, hotels have to offer superior conveniences to be entitled to a 5-star rating. These can include luxury baths, an on-site spa, swimming pools, fine dining kitchens and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in Southeast Missouri?
Our filter tool is the easiest way to find exactly what you're looking for. Check the "All inclusive" and "5-star" boxes to show the finest properties in Southeast Missouri where your meals, room, activities and entertainment are included in the upfront price. At these escapes, your trip is absolute indulgence from the moment you arrive.

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