The Best Hotels Closest to Biomuseo in Panama City for 2026

A modern building with colorful geometric shapes and a clear blue sky.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Compare popular hotels close to Biomuseo

Property	Property class	Guest rating
Hotel Plaza Herrera	4.0 star property	9.8 Exceptional 54 reviews	View
Hotel La Compañía Casco Antiguo	5.0 star property	9.8 Exceptional 379 reviews	View
Sofitel Legend Casco Viejo, Panama City	5.0 star property	9.8 Exceptional 773 reviews	View
La Concordia Boutique Hotel	4.0 star property	9.6 Exceptional 244 reviews	View
Amarla Boutique Hotel Casco Viejo Adults Only	3.0 star property	9.6 Exceptional 152 reviews	View

Hotels recommended for families near Biomuseo

A multi-story building with balconies, arched windows, and decorative railings.

Central Hotel Panama Casco Viejo

Casco Viejo

AED 885 total

includes taxes & fees

15 Dec - 16 Dec

Other attractions near Biomuseo

Amador Causeway

9.0/10 (1,902 reviews)

You can learn about the history of Ancon with a stop at Amador Causeway. Stroll along the seaside or visit the shops in this vibrant area.

See properties

Top Biomuseo Hotel Reviews

A spacious dining area with brick walls, a long wooden table set for a meal, and hanging spherical light fixtures.

Hotel La Compañía Casco Antiguo

Casco Viejo

10/10 Excellent

The hotel was BEAUTIFUL and in such a great area (Casco Vieja). I love the fact that you could totally hang out at the hotel at the bar, spa, or at one of the many restaurants. The only suggestion that I would make is for the rooms with terraces, to chairs to the terrace. We loved going out on the terrace, but there was no seating. However, even with this suggestion, it would only bring my rating down to a 9.5.

Andrea

A multi-story building with ornate balconies, large windows, and decorative moldings.

Hotel Plaza Herrera

Casco Viejo

10/10 Excellent

Sharon

A spacious lobby with a round coffee table, seating areas, and a large wall clock.

Sofitel Legend Casco Viejo, Panama City

Casco Viejo

10/10 Excellent

Dylan

A grand, illuminated building with a symmetrical facade, multiple balconies, and a prominent entrance.

La Concordia Boutique Hotel

Casco Viejo

10/10 Excellent

This hotel was great. Its location is perfect for a loop around the historic area. The staff is friendly, and most are fluent in English. Everything was clean and the room was spacious with a great balcony. They staff the front door 24/7 so no one unwelcome can enter. The rooftop bar and food was great. It isn't open 24/7 but there are plenty of other options for places to eat, and it is open at meal times. Wifi worked well.

Michael

A restaurant interior with checkered flooring, wooden tables, wicker chairs, and hanging wicker lamps.

Amarla Boutique Hotel Casco Viejo Adults Only

Casco Viejo

10/10 Excellent

Paul

A hotel with a covered entrance, multiple windows, and a balcony with plants.

Hotel San Felipe

Casco Viejo

10/10 Excellent

Carmen

A white building with multiple balconies, large windows, and decorative railings.

American Trade Hotel

Casco Viejo

10/10 Excellent

We arrived early from the David airport around 10am and we were just going to drop off our bags and they not only held our bags without question but then also took the time to make sure we had our room early if one was available! (Which there was!)-just be aware during their peak season it may not happen we were just lucky in the off season! The staff is SUPER friendly! The door men were super awesome and were always happy to help us! There will be an umbrella for you to get to your car if it’s...

Ashley

A multi-story building with balconies, large windows, and a clear blue sky.

Las Clementinas

Casco Viejo

10/10 Excellent

Kathy

A pool area with lounge chairs and umbrellas, surrounded by greenery and a multi-story building in the background.

Hyatt Regency Panama City

Bella Vista

10/10 Excellent

Michael

A balcony with wicker chairs and a view of the cityscape.

Ramada Plaza by Wyndham Panama Punta Pacifica

San Francisco

10/10 Excellent

Theon

A covered outdoor seating area with a view of a city skyline and water.

Plaza Paitilla Inn Hotel

San Francisco

10/10 Excellent

Natalie

A rooftop terrace with outdoor seating, a canopy bed, and a view of the sea.

Hotel Bardot Boutique

Casco Viejo

10/10 Excellent

Luz

Central Hotel Panama Casco Viejo

Casco Viejo

10/10 Excellent

Lourdes

A modern hotel lobby with a reception desk, seating area, and large windows.

The Executive Hotel

Bella Vista

10/10 Excellent

Debra

A spacious living room with blue sofas, a marble coffee table, and framed pictures on the walls.

Hotel Magnolia Boutique

Casco Viejo

10/10 Excellent

We had a lovely stay at this property. We stayed for 2 nights upon our arrival in Panama and for a night before flying home. The hotel staff were very welcoming, the room was clean and comfortable and the hotel is situated in a wonderful, eclectic and vibrant area. We could easily walk to great restaurants, wonderful sights or catch an Uber to go anywhere else. We loved it! One down side was that we had to climb up 3 floors (6 flights of stairs) to our room. There isn't an elevator, so pack...

Colleen

A rooftop bar with a city skyline view, outdoor seating, and a bar area with bottles and glasses.

Tantalo Hotel

Casco Viejo

10/10 Excellent

Great stay! We had wonderful service. The lady at the front desk recommend and arranged a taxi driver for a tour around the canal zone. We went to the Miraflores Loch visitors center and took the tour. It was amazing! We only had a few hours before heading off to Bocas del Toro, so we were able to see a lot prior to our flight out of the nearby airport. I highly recommend this hotel! It is loud on the weekend with the fabulous rooftop deck, and we loved it! Not a place for families or those...

Tasha

A high-rise hotel with multiple floors, a prominent "Residence Inn by Marriott" sign, and a "Panama Clinic" sign.

Residence Inn by Marriott Panama City

San Francisco

10/10 Excellent

We read a few pretty bad reviews about this hotel but booked anyway. So now I’m here to report back to my fellow Hotels members. Here’s the deal. The view is amazing. The roof top pool, the gym and the morning and evening views from roof top are SICK!! I’ll upload a pic. 😊 That comment about the mold. Forget about that person. The negative comments about breakfast. Well, yeah they could do better for sure but it’s not a deal maker. If you want a really nice breakfast go to a local...

Chris

A resort with a pool area, lounge chairs, and a view of a bridge at night.

Radisson Hotel Panama Canal

Amador

10/10 Excellent

Patti

Frequently Asked Questions

What's the area like around Biomuseo?

Biomuseo is located in a vibrant area of Ancon known for its array of dining options and major shopping area. You'll find 1260 hotels and other accommodations within a few miles for a convenient home base.

What's the best hotel to stay near Biomuseo?

Radisson Hotel Panama Canal is one of the top choices for your stay based on our traveler data, and this hotel offers 2 outdoor pools and 2 restaurants. It's located just a short 0.9 mi (1.5 km) from Biomuseo. Another good choice is La Palma Experience, located just 0.7 mi (1.1 km) away.

How many hotels will I be able to find near Biomuseo?

Expedia has 1260 hotels and other accommodations a few miles from Biomuseo.

If I need to cancel the hotel reservation for my stay near Biomuseo, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to get the best options available near Biomuseo.

Where can I learn more about changing or cancelling my trip in the area near Biomuseo?

For more information about updating your stay near Biomuseo or cancelling it, click here.

What can I see and do near Biomuseo?

Interoceanic Canal Museum, Mola Museum, and Museum of History Panama feature a variety of fascinating exhibits to see while you're in town. Sights like Panama Canal Railway, Iglesia del Carmen, and Paseo de Las Bovedas are must-sees while exploring the area. You can catch a show at National Theater, Anita Villalaz Theater, and Amador Theater.

Find hotels near Biomuseo, Panama City from AED 300

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Property class

Guest rating

Our top choices for Biomuseo hotels

1. Hotel Plaza Herrera

2. Hotel La Compañía Casco Antiguo

3. Sofitel Legend Casco Viejo, Panama City

4. La Concordia Boutique Hotel

5. Amarla Boutique Hotel Casco Viejo Adults Only

6. American Trade Hotel

7. Hotel San Felipe

8. Hotel Bardot Boutique

9. Casco View Life Residences

10. Central Hotel Panama Casco Viejo

11. The Balboa Inn

12. Hotel Magnolia Boutique

13. Tantalo Hotel

14. Radisson Hotel Panama Canal

15. Corcho

16. Viajero Casco Viejo Hostel

17. La Cuadra by Wynwood House

18. The Beach House

19. La Palma Experience

20. MARINN Tropical Vibes Hotel

Compare popular hotels close to Biomuseo

Hotels recommended for families near Biomuseo

Central Hotel Panama Casco Viejo

Other attractions near Biomuseo

Amador Causeway

Top Biomuseo Hotel Reviews

Hotel La Compañía Casco Antiguo

10/10 Excellent

Frequently Asked Questions

What's the area like around Biomuseo?

What's the best hotel to stay near Biomuseo?

How many hotels will I be able to find near Biomuseo?

If I need to cancel the hotel reservation for my stay near Biomuseo, will I receive a refund?

Where can I learn more about changing or cancelling my trip in the area near Biomuseo?

What can I see and do near Biomuseo?