Search Hotels in Knox County
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for Knox County hotels
1. Tiny Cozy Cottage in Edina, MO
Tiny Cozy Cottage in Edina, MOEdina
10.0 out of 10, Exceptional, (17 reviews)
"The cottage was super cute with lovely little touches. We were very comfortable and had everything we needed! We would stay here again."
Laura
The price is AED 281
AED 376 total
includes taxes & fees
30 Aug - 31 Aug
2. Unique 2-bedroom house in Edina for a relaxing getaway
Unique 2-bedroom house in Edina for a relaxing getawayEdina
10.0 out of 10, Exceptional, (1 review)
"Very accommodating host. We had a dog, cat, plants, & enclosed trailer (moving). He was great to help us out when no one else had room for all this mess. Clean and comfortable. Excellent neighborhood for walking the dog."
T B.
The price is AED 264
AED 358 total
includes taxes & fees
8 Sep - 9 Sep
3. Edina Missouri New Cabin in Rural Area
Edina Missouri New Cabin in Rural AreaEdina
10.0 out of 10, Exceptional, (39 reviews)
"House had everything we needed. Had a great stay!!"
Ron K.
4. Lost Branch Lodge. Complete exterior remodel, spring 2026!
Lost Branch Lodge. Complete exterior remodel, spring 2026!Brashear
10.0 out of 10, Exceptional, (189 reviews)
"Our stay at Lost Bridge Lodge was nothing but pure magic! The home was in pristine condition! Everything matched the description of the retreat to the word. Our family enjoyed all the new memories we made and look forward to staying again in the near future!"
Melissa W.
5. Newly Updated Countryside Home in South Gorin!
Newly Updated Countryside Home in South Gorin!South Gorin
6. Newly Updated Countryside Home in South Gorin!
Newly Updated Countryside Home in South Gorin!South Gorin
10.0 out of 10, Exceptional, (1 review)
"It was remote but the property was recently renovated. It was very quiet too."
Kathy Ann W.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Top Knox County Hotel Reviews
Super 8 by Wyndham Macon
10/10 Excellent
Explore a world of travel with Expedia
- Lodges in Northeast Missouri
- 3 Star Hotels in Lentner
- Kahoka Hotels
- 4 Star Hotels in Hurdland
- Wyndham Hotels in Shelbyville
- 2 Star Hotels in Kahoka
- 4 Star Hotels in Downing
- Hotels with Bars in Kirksville
- Red Roof Inn Hotels in Northeast Missouri
- Pet-Friendly Hotels in Northeast Missouri
- Independent Hotels in Edina
- Golf Hotels in La Plata
- Hotel Wedding Venues Hotels in Macon
- Independent Hotels in La Plata
- 3 Star Hotels in Edina
- Wyndham Hotels in La Plata
- Motels in Gibbs
- Wyndham Hotels in Kahoka
- Vacation Homes in La Plata
- Casino Hotels in Northeast Missouri
- Cabin Rentals in La Plata
- 4 Star Hotels in Macon
- 5 Star Hotels in Novinger
- 5 Star Hotels in Downing
- Cabin Rentals in Hurdland
- Independent Hotels in Memphis
- Vacation Homes in Gibbs
- Hilton Hotels in Kahoka
- Vacation Homes in Macon
- 3 Star Hotels in Shelbina
- Cabin Rentals in Novinger
- Budget Host Hotels in Maywood
- Pet-Friendly Hotels in Kirksville
- Hotels with smoking rooms in Macon
- Best Western Hotels in Northeast Missouri
- 4 Star Hotels in Novinger
- Wyndham Hotels in Shelbina
- 4 Star Hotels in La Plata
- Luxury Hotels in Northeast Missouri
- Marriott Hotels & Resorts in Rutledge
- B&B in Shelbina
- Independent Hotels in Kirksville
- La Plata Hotels
- Family Hotels in Northeast Missouri
- 4 Star Hotels in Kahoka
- Wyndham Hotels in Macon
- Best Western Hotels in Shelbina
- Hotels near Maples Repertory Theatre
- Condo Rentals in Canton
- La Quinta Inn & Suites Hotels in Northeast Missouri
- Flights from Albuquerque (ABQ) to Kirksville (IRK)
- Flights from Lagos (LOS) to Kirksville (IRK)
- Flights from Cocos Islands (CCK) to Kirksville (IRK)
- Flights from Ketchikan (KTN) to Kirksville (IRK)
- Flights from Kaltag (KAL) to Kirksville (IRK)
- Flights from Madison (MSN) to Kirksville (IRK)
- Flights from Liverpool (LPL) to Kirksville (IRK)
- Flights from Jeddah (JED) to Kirksville (IRK)
- Flights from Anchorage (ANC) to Kirksville (IRK)
- Flights from Dalaman (DLM) to Kirksville (IRK)
- Flights from Bogotá (BOG) to Kirksville (IRK)
- Flights from Tunica (UTM) to Kirksville (IRK)
- Flights from Jabalpur (JLR) to Kirksville (IRK)
- Flights from Holland (HLM) to Kirksville (IRK)
- Flights from Oslo (OSL) to Kirksville (IRK)
- Flights from Vojens (SKS) to Kirksville (IRK)
- Flights from Pristina (PRN) to Kirksville (IRK)
- Flights from Tamchy (IKU) to Kirksville (IRK)
- Flights from Marquette (MQT) to Kirksville (IRK)
- Flights from Columbia (COU) to Kirksville (IRK)
- Flights from Hurdland
- Flights from Kahoka
- Flights from Mojave (MHV) to Kirksville (IRK)
- Flights from Prince Albert (YPA) to Kirksville (IRK)
- Flights from Greenville (PGV) to Kirksville (IRK)
- Flights from Kubin Island (KUG) to Kirksville (IRK)
- Flights from La Plata
- Flights from Shelbina
- Flights from Northeast Missouri
- Flights from Frankfurt (FRA) to Kirksville (IRK)
- Flights from Kirksville
- Flights from Camiri (CAM) to Kirksville (IRK)
- Flights from Macon
- Flights from Novinger
- Flights from El Paso (ELP) to Kirksville (IRK)
- Flights from Valparaiso (VPZ) to Kirksville (IRK)
- Flights from Bangor (BGR) to Kirksville (IRK)
- Flights from Halifax (YHZ) to Kirksville (IRK)
- Flights from Denver (DEN) to Kirksville (IRK)
- Flights from Huntsville (HSV) to Kirksville (IRK)
- Flights from Kirksville Municipal
- Flights to Macon
- Flights from Santa Maria (RIA) to Kirksville (IRK)
- Flights from Orlando (SFB) to Kirksville (IRK)
- Flights from Yangon (RGN) to Kirksville (IRK)
- Flights from Alta Floresta (AFL) to Kirksville (IRK)
- Flights from Santa Isabel do Rio Negro (IRZ) to Kirksville (IRK)
- Flights from Chicago (PWK) to Kirksville (IRK)
- Flights from Glasgow (GLA) to Kirksville (IRK)
- Flights from Phoenix (PHX) to Kirksville (IRK)
