Find hotels in South Central Houston, Houston from AED 241

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Check prices for these dates

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3 May - 4 May
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4 May - 5 May
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8 May - 10 May
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15 May - 17 May

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Our top choices for South Central Houston hotels

Laptop workspace, blackout drapes, soundproofing, iron/ironing board

Downtowner Inns - Houston Downtown

Downtowner Inns - Houston Downtown
2.0 star property
South Central Houston
8.6 out of 10, Excellent, (135 reviews)
"Okay for a short stay. For a motel it is in a fairly decent condition."
United States
Nick
The price is AED 321
AED 376 total
includes taxes & fees
14 May - 15 May
Downtowner Inns - Houston Downtown
Terrace/patio

Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center
4.5 star property
South Central Houston
8.4 out of 10, Very Good, (1,897 reviews)
"Excellent stay while there for a tournament near NRG. Perfect location. The staff was so wonderful! "
United States
Lindsy
The price is AED 403
AED 476 total
includes taxes & fees
24 May - 25 May
Hilton Houston Plaza/Medical Center
House | 3 bedrooms, Internet

Luxurious 3 Bed3 Bath Near Downtown Houston

Luxurious 3 Bed3 Bath Near Downtown Houston
2.0 star property
South Central Houston
10.0 out of 10, Exceptional, (2 reviews)
"This was made for a perfect family vacation… super clean kid friendly with an awesome view of Houston for the adults on rooftop "
United States
Ebony
The price is AED 370
AED 1,345 total
includes taxes & fees
6 May - 7 May
Luxurious 3 Bed3 Bath Near Downtown Houston
Exterior detail

Sentral Forme Houston

Sentral Forme Houston
4.5 star property
South Central Houston
9.0 out of 10, Wonderful, (22 reviews)
"Verry nice and staff was very helpful. Will stay again"
United States
Carolyn
The price is AED 768
AED 1,006 total
includes taxes & fees
3 Jun - 4 Jun
Sentral Forme Houston
Reception

Americas Best Value Inn Medical Center Downtown

Americas Best Value Inn Medical Center Downtown
2.0 star property
South Central Houston
8.0 out of 10, Very Good, (1,003 reviews)
"Was nice place to stay for a one night trip."
United States
Amanda
The price is AED 309
AED 362 total
includes taxes & fees
5 May - 6 May
Americas Best Value Inn Medical Center Downtown
Outdoor pool, free cabanas, pool umbrellas

The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District
4.0 star property
South Central Houston
9.2 out of 10, Wonderful, (1,149 reviews)
"Fantastic reasonably priced property."
United States
William
The price is AED 625
AED 778 total
includes taxes & fees
17 May - 18 May
The Westin Houston Medical Center/Museum District
Premium bedding, pillowtop beds, minibar, in-room safe

Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District
4.5 star property
South Central Houston
9.2 out of 10, Wonderful, (1,010 reviews)
"It was a wonderful place to stay will be coming back again."
United States
Jesse
The price is AED 749
AED 1,043 total
includes taxes & fees
25 May - 26 May
Hotel Zaza Houston Museum District
Reception

Wanderstay Boutique Hotel

Wanderstay Boutique Hotel
3.0 star property
South Central Houston
9.8 out of 10, Exceptional, (72 reviews)
"Solo trip and it was a perfect location staff was nice and it was nice and clean!! Would stay there again. "
United States
Sharon
The price is AED 442
AED 517 total
includes taxes & fees
20 May - 21 May
Wanderstay Boutique Hotel
Breakfast and dinner served

DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites
4.0 star property
South Central Houston
8.4 out of 10, Very Good, (573 reviews)
"Staff was wonderful "
United States
Lynn
The price is AED 408
AED 477 total
includes taxes & fees
17 May - 18 May
DoubleTree by Hilton Houston Medical Center Hotel & Suites
Outdoor pool

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
3.5 star property
South Central Houston
9.6 out of 10, Exceptional, (212 reviews)
"Beautiful place and wonderful management. Would definitely stay again! "
United States
Shelly
The price is AED 760
AED 945 total
includes taxes & fees
14 May - 15 May
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
Dinner served, American cuisine

Houston Marriott Medical Center/Museum District

Houston Marriott Medical Center/Museum District
4.0 star property
South Central Houston
9.0 out of 10, Wonderful, (1,001 reviews)
"Right in the center of the Medical District. Didn’t even have to go outside to get to my wife’s appointment. "
United States
Dominick
The price is AED 658
AED 889 total
includes taxes & fees
29 May - 30 May
Houston Marriott Medical Center/Museum District
Lobby

Hilton University of Houston

Hilton University of Houston
3.5 star property
South Central Houston
9.0 out of 10, Wonderful, (936 reviews)
"The hotel was clean, staff were friendly and the location was perfect for our event. I will definitely stay there again. "
United States
Ricardo
The price is AED 506
AED 592 total
includes taxes & fees
22 May - 23 May
Hilton University of Houston
House | Private kitchen

Downtown Houston 3BR Bachelorette Escape

Downtown Houston 3BR Bachelorette Escape
2.0 star property
South Central Houston
9.8 out of 10, Exceptional, (6 reviews)
"Everything was great. Look no further and book this property. "
United States
Iesheal
The price is AED 664
AED 1,690 total
includes taxes & fees
28 May - 29 May
Downtown Houston 3BR Bachelorette Escape
Exterior

InterContinental Houston by IHG

InterContinental Houston by IHG
4.0 star property
South Central Houston
9.2 out of 10, Wonderful, (1,004 reviews)
"Excellent Hotel! Great price and beautiful and clean , 5 star hotel "
United States
Adelina
The price is AED 621
AED 800 total
includes taxes & fees
24 May - 25 May
InterContinental Houston by IHG
Exterior

La Maison in Midtown an urban B&B

La Maison in Midtown an urban B&B
3.5 star property
South Central Houston
9.8 out of 10, Exceptional, (569 reviews)
"Loved the area, the staff was super friendly and accomodating. "
United States
Silvia Alejandra
The price is AED 625
AED 731 total
includes taxes & fees
8 May - 9 May
La Maison in Midtown an urban B&B
Standard Room, 1 King Bed | 1 bedroom, premium bedding, blackout drapes, free WiFi

Southmore Boulevard Motel

Southmore Boulevard Motel
2.0 star property
South Central Houston
5.6 out of 10, (237 reviews)
"I enjoyed my stay at this hotel."
United States
Tamela
The price is AED 206
AED 241 total
includes taxes & fees
4 May - 5 May
Southmore Boulevard Motel
Lobby

Extended Stay America Suites Houston Med Ctr Braeswood Bl

Extended Stay America Suites Houston Med Ctr Braeswood Bl
2.5 star property
South Central Houston
5.8 out of 10, (1,002 reviews)
"Room was clean and had a very comfortable bed We had a very pleasant stay. We were very comfortable and felt quite safe st this property. "
United States
Nilda
The price is AED 274
AED 322 total
includes taxes & fees
10 May - 11 May
Extended Stay America Suites Houston Med Ctr Braeswood Bl
Reception

Golden Motel Near Houston Medical Center

Golden Motel Near Houston Medical Center
2.5 star property
South Central Houston
2.0 out of 10, (1 review)
"Room smelt like cigarettes burnt wholes in the wall and bed sheet all 6 walls had stains toilet seat look like someone stood on it "
United States
Jacari
The price is AED 192
AED 244 total
includes taxes & fees
11 May - 12 May
Golden Motel Near Houston Medical Center
Interior

Wanderstay Houston Hostel

Wanderstay Houston Hostel
2.0 star property
South Central Houston
8.2 out of 10, Very Good, (199 reviews)
"it was a great experience, staff was kind and helpful. "
United States
James
The price is AED 224
AED 262 total
includes taxes & fees
6 May - 7 May
Wanderstay Houston Hostel
House | 4 bedrooms, soundproofing, bed sheets

Posh Dtwn Midtown Home w Stunning Roof-topterrace

Posh Dtwn Midtown Home w Stunning Roof-topterrace
3.0 star property
South Central Houston
The price is AED 736
AED 2,357 total
includes taxes & fees
26 May - 27 May
Posh Dtwn Midtown Home w Stunning Roof-topterrace
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in South Central Houston

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Exterior
La Maison in Midtown an urban B&B
3.5 star property
9.8
Exceptional
569 reviews
View
Reception
Wanderstay Boutique Hotel
3.0 star property
9.8
Exceptional
72 reviews
View
Outdoor pool, free cabanas, pool umbrellas
The Westin Houston Medical Center/Museum District
4.0 star property
9.2
Wonderful
1,149 reviews
View
Exterior detail
Sentral Forme Houston
4.5 star property
9.0
Wonderful
22 reviews
View
Premium bedding, pillowtop beds, minibar, in-room safe
Hotel Zaza Houston Museum District
4.5 star property
9.2
Wonderful
1,010 reviews
View

Where to stay in South Central Houston

Find the best South Central Houston areas and neighborhoods for the activities you enjoy most.

Downtown Houston

Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.

The Galleria

Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Williams Tower.

Houston_TexasChildrensHospital_553248635389801905_9

Texas Medical Center

Boasting the world's largest medical complex, this Houston neighborhood offers access to over 60 medical institutions and is served by the METRORail Red Line. Explore the John P. McGovern Historical Collections and Research Center for a unique experience.

Montrose

Unique features of Montrose include the theaters and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.

Photo by George Zimzores
Open Photo by George Zimzores

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Downtown Transit Center Station.

Top South Central Houston Hotel Reviews

Sentral Forme Houston

Sentral Forme Houston

6/10 Okay
"This property was clean and new. However there were only 2 towels in each guest room and no towels at the pool because they are a “residence”. However for my husband and I, our only 2 shower towels had to be taken to the pool and were wet for later use, this was a problem. Also there was a “scheduled” power outage in Houston from 7-9am that we were not Told about until AFTER we checked in. The outage lasted more like 3 hours during which time guest rooms had NO power (no generator) and there was NO hot water. Didn’t see anyone else in Houston down so not sure how accurate this was. "
Amber 1-night trip
Posted 5 hours ago
Sentral Forme Houston

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Frequently asked questions

What's it like in South Central Houston?
Travelers are sure to enjoy a stay in Houston's South Central Houston neighborhood. Be sure to check out Continental Club and Children's Museum of Houston as part of your South Central Houston travel plans.
What's the best accommodation in South Central Houston?
Based on our traveler data, Hilton Houston Plaza/Medical Center is one of the top choices for your stay in South Central Houston. This hotel is a short 9-minute walk from MD Anderson Cancer Center, and it offers 2 restaurants and 2 bars. Other good options for your stay in the area include Hotel Zaza Houston Museum District and InterContinental Houston by IHG.
How many hotels can I expect to find in the South Central Houston area?
Expedia has 1120 hotels and other accommodations in South Central Houston to choose from, making this an ideal home base for exploring the greater Houston area.
If I need to cancel my hotel reservation in South Central Houston, will I receive a refund?
Yes, the majority of hotel room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to review the best options available in South Central Houston.
Where can I learn more about changing or cancelling my trip to South Central Houston?
To access more information about changing or cancelling your trip to South Central Houston, go to https://www.expedia.com/service/.
What is there to do around this Houston neighborhood?
Spend some time exploring the great outdoors at Hermann Park, Cullen Sculpture Garden, and Bagby Dog Park. Continental Club and Children's Museum of Houston are some other stops to visit in the neighborhood. Toyota Center and Daikin Park are some favorite places to visit in the area around South Central Houston. Shape Community Center and Project Row Houses are also worth a visit when you're out sightseeing in Houston.
How can I get around South Central Houston and the greater Houston area?
For a quick way to explore the city, catch a ride on metro transit at Elgin/Third Ward Station, TSU/UH Athletics District Station, or Ensemble/HCC Station. If you want to venture out of town, M. D. Anderson Station is the closest train station. You can also catch a ride at Kinder Station.