The Best Hotels Closest to Lester E. Cox Medical Center South in Springfield for 2026

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Our top choices for Lester E. Cox Medical Center South hotels

A modern reception area with a 'Welcome to Hampton' sign, a reception desk, a dining area with a table and chairs, a sofa, and a patterned rug.

A hotel lobby with a reception desk, seating area, and a clock on the wall.

A snack and beverage section with various products and a microwave.

A gym with a treadmill, weights, and exercise balls.

1. Hampton Inn Springfield-South

Galloway Village, 2 km from Lester E. Cox Medical Center South

Ashley

AED 387

AED 439 total

includes taxes & fees

8 Nov - 9 Nov

An outdoor patio area with red seating, a fire feature, and tables and chairs.

A modern hotel lobby with a bar, seating area, kitchen, and a TV.

A modern living room with a sectional sofa, a coffee table, and yellow armchairs. There is a dining area with a table and chairs in the background.

A modern hotel room with a large bed, a desk with a chair, a mirror, and a painting on the wall.

2. Homewood Suites by Hilton Springfield Medical District

Southside, 1.4 km from Lester E. Cox Medical Center South

Aaron

AED 479

AED 544 total

includes taxes & fees

22 Nov - 23 Nov

A hotel lobby with a reception desk, a sofa, and a seating area.

A hotel lobby with a seating area, a television, and artwork on the walls.

A buffet with various food items, including omelets and baked goods, served in metal trays.

A hotel room with a blue sofa, two beds, a nightstand, and a lamp.

3. Holiday Inn Express and Suites Springfield Medical District by IHG

1.6 km from Lester E. Cox Medical Center South

Loyola

AED 481

AED 546 total

includes taxes & fees

23 Nov - 24 Nov

A hotel room with two beds, a desk, a chair, a TV, and a bathroom with a sink and mirror.

A modern hotel room with a sofa, armchair, and a dining area with a kitchen in the background.

A multi-story hotel with a prominent "Candlewood Suites" sign, a parking lot, and a landscaped entrance area.

A modern kitchen with a stainless steel microwave, a coffee maker, and a refrigerator.

4. Candlewood Suites Springfield-Medical District

0.9 km from Lester E. Cox Medical Center South

Beau

AED 433

AED 492 total

includes taxes & fees

1 Nov - 2 Nov

A modern restaurant with a bar area, large windows, and a variety of seating options.

A spacious living area with large windows, a bar, and modern furniture.

A modern hotel building with a prominent 'element by Westin' sign, multiple floors, and a covered entrance area.

An indoor swimming pool with clear blue water, surrounded by lounge chairs and a large windowed area.

5. Element by Marriott Springfield South

Meador Park, 1.5 km from Lester E. Cox Medical Center South

Nathaniel

AED 547

AED 621 total

includes taxes & fees

22 Nov - 23 Nov

An outdoor patio area with wicker furniture, a central fire pit, and large windows.

An indoor swimming pool with clear water, surrounded by a tiled floor and a glass wall.

A hotel with a stone facade, large windows, and a clear blue sky.

A lobby with a fireplace, large windows, and a view of the outdoors.

6. Hilton Garden Inn Springfield, MO

Lake Springfield, 2.7 km from Lester E. Cox Medical Center South

Darryl

AED 404

AED 462 total

includes taxes & fees

22 Nov - 23 Nov

A spacious lounge area with comfortable seating, a fireplace, and artwork on the walls.

A modern kitchen with a central island, bar stools, a dining table, and a bar area.

An outdoor patio with wicker furniture, a round table, and a grill area.

A buffet setup with various food items, a clock, and a coffee machine.

7. Residence Inn by Marriott Springfield

Southside, 0.8 km from Lester E. Cox Medical Center South

Marilyn

AED 403

AED 457 total

includes taxes & fees

23 Nov - 24 Nov

A hotel room with two beds, a desk with a computer, a TV, and a coffee maker.

A hotel dining area with multiple tables and chairs, a kitchen counter with coffee machines, and a wall-mounted clock.

A compact hotel room with a sofa, a small table, a TV, and a desk with a coffee machine.

A hotel reception area with a counter displaying various alcohol bottles, a menu board, and artwork on the walls.

8. La Quinta Inn & Suites by Wyndham Springfield South

Seminole Holland, 2.8 km from Lester E. Cox Medical Center South

Denise

AED 323

AED 374 total

includes taxes & fees

22 Nov - 23 Nov

A modern living room with a flat-screen TV, a fireplace, a sofa, and a dining area with a kitchen counter.

A spacious living area with a sofa, a ceiling fan, a staircase, and a kitchen area.

A modern living room with a fireplace, a sofa, a TV, and a staircase leading to a bedroom.

A kitchen area with a coffee machine, a buffet setup, and a dining table with chairs.

9. MainStay Suites Springfield South - Battlefield Rd

Bradford Park, 1.7 km from Lester E. Cox Medical Center South

Arthur

AED 340

AED 386 total

includes taxes & fees

24 Nov - 25 Nov

An indoor swimming pool with a glass ceiling, surrounded by lounge chairs and a view of the outdoors.

A Comfort Inn hotel with a modern facade, a covered entrance, and a parking lot.

A hotel room with a large bed, a wooden nightstand with a phone, two wall-mounted lamps, and a window with curtains.

A modern living room with blue sofas, a stone accent wall, and a bookshelf.

10. Comfort Inn South - Springfield

Galloway Village, 2.3 km from Lester E. Cox Medical Center South

Roger

AED 336

AED 381 total

includes taxes & fees

22 Nov - 23 Nov

A modern hotel lobby with a leather sofa, green chairs, a black coffee table, and a kitchen area with a green countertop.

A swimming pool with a lifeguard tower, surrounded by a fence and seating area.

A spacious indoor dining area with multiple round tables and chairs, large windows, and a modern staircase.

A hotel room with two beds, a desk with a chair, a flat-screen TV, and a large window with curtains.

11. The Bradford Hotel, an Ascend Collection Hotel

Bradford Park, 0.5 km from Lester E. Cox Medical Center South

Richard

AED 302

AED 343 total

includes taxes & fees

22 Nov - 23 Nov

A hotel lobby with a reception desk, a staircase, and a seating area.

A hotel room with a bed, a chair, a nightstand with a lamp, and framed pictures on the wall.

A swimming pool with a hot tub, tiled floor, and a few lounge chairs.

A kitchen with a wooden table and chairs, a coffee machine, a fruit juicer, and a refrigerator.

12. Sleep Inn Springfield South I60 near Medical District

1.8 km from Lester E. Cox Medical Center South

Dina

AED 292

AED 332 total

includes taxes & fees

25 Nov - 26 Nov

A hotel room with a large bed, a chair, a nightstand, a lamp, and a door.

A hotel reception area with a reception desk, a framed artwork, and an exit sign.

A hotel with a prominent sign for 'extended stay America' and a parking lot with several cars.

A compact kitchenette with white cabinets, a sink, a microwave, and a refrigerator.

13. Extended Stay America Select Suites Springfield South

Southside, 0.9 km from Lester E. Cox Medical Center South

Crystal

AED 264

AED 300 total

includes taxes & fees

30 Oct - 31 Oct

A hotel room with a bed, bedside table, lamp, and a painting of a sunset.

A lobby with a mural, seating area, and a refrigerator labeled 'NOURISH' and 'RECHARGE'.

A modern dining area with blue chairs and white tables, a flat-screen TV mounted on the wall, and a wooden cabinet with items on it.

14. Clarion Pointe Springfield Southeast

Galloway Village, 4.8 km from Lester E. Cox Medical Center South

Debbie

AED 309

AED 350 total

includes taxes & fees

12 Nov - 13 Nov

A spacious indoor dining area with multiple tables and chairs, a kitchen area, and large windows allowing natural light.

A spa area with a hot tub, a pool, and a seating area with tables and chairs.

A modern kitchen with a long counter, wooden cabinets, and a backsplash.

A modern lobby with a reception desk, seating area, and a high ceiling with recessed lighting.

15. Drury Inn & Suites Springfield, MO

11.2 km from Lester E. Cox Medical Center South

Michelle

AED 389

AED 446 total

includes taxes & fees

1 Nov - 2 Nov

An outdoor seating area with wicker chairs and a fire feature.

A hotel reception area with a modern design, featuring two reception desks, a mounted television, and a wall-mounted sign indicating check-in and check-out times.

A rustic building with large windows and a gabled roof.

A spacious outdoor area with a wooden structure and a large building with multiple windows.

16. Holiday Inn Express & Suites Springfield North by IHG

11.8 km from Lester E. Cox Medical Center South

Jerry

AED 371

AED 421 total

includes taxes & fees

22 Nov - 23 Nov

A cozy living room with a stone fireplace, comfortable seating, and a large mirror reflecting the room.

A hotel with a clear entrance, a covered waiting area, and a parking lot.

A hotel room with a bed, bedside lamps, a desk with a sink, and a framed picture on the wall.

A hotel lobby with a large bar area, seating, a fireplace, and framed pictures on the walls.

17. Hampton Inn Springfield-Southeast

Galloway Village, 4.9 km from Lester E. Cox Medical Center South

teresa

AED 390

AED 443 total

includes taxes & fees

22 Nov - 23 Nov

A modern hotel room with a kitchenette, a flat-screen TV, a bed, and a large window.

A modern hotel room with a dark grey sofa, a wooden side table, a desk with a chair, and two abstract paintings on the walls.

An outdoor patio area with a stone wall, wooden pergola, and seating arrangements including a sofa and chairs.

A modern kitchen with wooden cabinets, a countertop with various kitchen items, and a wall-mounted shelf with decorative objects.

18. SpringHill Suites by Marriott Springfield North

Parkwood, 11.6 km from Lester E. Cox Medical Center South

Amanda

AED 419

AED 492 total

includes taxes & fees

8 Nov - 9 Nov

An outdoor patio with stone walls, round tables, chairs, and umbrellas.

A modern hotel room with a stone accent wall, a flat-screen TV, a fireplace, a sofa, a dining area, and a patterned carpet.

A Fairfield Inn & Suites Marriott hotel with a modern design, featuring a prominent entrance and a parking lot.

An indoor swimming pool with clear glass walls, lounge chairs, and a lifeguard chair.

19. Fairfield Inn & Suites by Marriott Springfield North

Doling, 10.7 km from Lester E. Cox Medical Center South

Kristal

AED 385

AED 445 total

includes taxes & fees

8 Nov - 9 Nov

A modern hotel room with a large bed, a desk with a sink, and a view of the cityscape through large windows.

A bar area with a checkered floor, bar stools, and a long counter with a barista station.

A modern building with a prominent V-shaped entrance and large glass windows.

A rooftop lounge with wooden flooring, various seating options including sofas and chairs, a round table, and potted plants.

20. Hotel Vandivort

Downtown Springfield, 6.8 km from Lester E. Cox Medical Center South

Laurie-Ann

AED 646

AED 736 total

includes taxes & fees

8 Nov - 9 Nov

View all properties

Compare popular hotels close to Lester E. Cox Medical Center South

Property	Property class	Guest rating
Hampton Inn Springfield-South	9.4 Exceptional 724 reviews	View
Homewood Suites by Hilton Springfield Medical District	9.4 Exceptional 572 reviews	View
Holiday Inn Express and Suites Springfield Medical District by IHG	9.4 Exceptional 1,002 reviews	View
Candlewood Suites Springfield-Medical District	9.2 Wonderful 436 reviews	View
Element by Marriott Springfield South	9.2 Wonderful 161 reviews	View

Top Lester E. Cox Medical Center South Hotel Reviews

Bass Pro Shops Angler's Lodge

10/10 Excellent

"Great staff and very clean"

Holiday Inn Express and Suites Springfield Medical District by IHG

10/10 Excellent

"NA"

MainStay Suites Springfield South - Battlefield Rd

10/10 Excellent

"The bathroom countertop was not clean. When I walked up stairs to our room there was a flosser laying on the stairs and several wrappers laying on the ground. Staff was friendly, room was great , beds comfy and room had large fridge and stove and dishwasher. I was surprised!!! Other than the trash outside it was a very nice hotel and would stay again!!!"

The Bradford Hotel, an Ascend Collection Hotel

10/10 Excellent

"Perfect while a family member was in the hospital"

Residence Inn by Marriott Springfield

8/10 Good

"I’ve stayed here a couple of times. Fairly clean hotel. Nice staff. Great for families so that you have room and the ability to cook if you’d like."

Peaceful Retreat near Medical Mile in Springfield

10/10 Excellent

"We had a wonderful time and the house is very warm, welcoming and clean. Thank you."

Element by Marriott Springfield South

10/10 Excellent

"Clean, all staff were helpful and friendly. Great place and I have no complain"

Cozy Central Home by CoxHealth & MSU - Fenced Yard

10/10 Excellent

"We had a great stay. In town for a wedding reception, we arrived Friday afternoon and left Sunday morning. The house was clean, bright and spacious. The dog loved the back yard. Morning coffee on the deck in the shade of the weeping willow was relaxing."

Comfortable Home Near CoxHealth & MSU - Fenced Yard

10/10 Excellent

"The house was better than described, very comfortable and everything is right there I mean right there, I was pleasantly surprised on how I was able to get ot everything in no time flat, the only thing that was a hike was the airport."

Frequently asked questions

What's the area like around Lester E. Cox Medical Center South?

Lester E. Cox Medical Center South is located in a welcoming area of Springfield that travelers like for its sporting events and opera houses. If you're looking for a convenient place to stay, check out the 19 hotels and other accommodations you'll find within a mile.

What's the best hotel to stay close to Lester E. Cox Medical Center South?

Residence Inn by Marriott Springfield is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a restaurant. It's located just a short 0.5 mi (0.8 km) from Lester E. Cox Medical Center South. Other good choices close by include The Bradford Hotel, an Ascend Collection Hotel and Extended Stay America Select Suites Springfield South.

How many hotels are there close to Lester E. Cox Medical Center South?

Expedia has 19 hotels and other accommodations within a mile from Lester E. Cox Medical Center South.

If I need to cancel the hotel reservation for my stay near Lester E. Cox Medical Center South, will I receive a refund?

Yes, the majority of hotel room reservations are refundable if you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to get the top deals on offer near Lester E. Cox Medical Center South.

Where can I learn more about changing or cancelling my trip in the area near Lester E. Cox Medical Center South?

For more information about picking new dates or cancelling your stay near Lester E. Cox Medical Center South, go to https://www.expedia.com/service/.

What can I see and do near Lester E. Cox Medical Center South?

You'll want to browse the exhibits at Springfield Art Museum and Discovery Center of Springfield. Sights like Abou Ben Adhem Shrine and Landers Theater highlight some of the local culture. You might spend a leisurely day outdoors at Nathanael Greene/Close Memorial Park and Mizumoto Japanese Stroll Garden.

Find hotels near Lester E. Cox Medical Center South, Springfield from AED 300

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Our top choices for Lester E. Cox Medical Center South hotels

1. Hampton Inn Springfield-South

2. Homewood Suites by Hilton Springfield Medical District

3. Holiday Inn Express and Suites Springfield Medical District by IHG

4. Candlewood Suites Springfield-Medical District

5. Element by Marriott Springfield South

6. Hilton Garden Inn Springfield, MO

7. Residence Inn by Marriott Springfield

8. La Quinta Inn & Suites by Wyndham Springfield South

9. MainStay Suites Springfield South - Battlefield Rd

10. Comfort Inn South - Springfield

11. The Bradford Hotel, an Ascend Collection Hotel

12. Sleep Inn Springfield South I60 near Medical District

13. Extended Stay America Select Suites Springfield South

14. Clarion Pointe Springfield Southeast

15. Drury Inn & Suites Springfield, MO

16. Holiday Inn Express & Suites Springfield North by IHG

17. Hampton Inn Springfield-Southeast

18. SpringHill Suites by Marriott Springfield North

19. Fairfield Inn & Suites by Marriott Springfield North

20. Hotel Vandivort

Compare popular hotels close to Lester E. Cox Medical Center South

Top Lester E. Cox Medical Center South Hotel Reviews

Bass Pro Shops Angler's Lodge

Holiday Inn Express and Suites Springfield Medical District by IHG

MainStay Suites Springfield South - Battlefield Rd

The Bradford Hotel, an Ascend Collection Hotel

Residence Inn by Marriott Springfield

Peaceful Retreat near Medical Mile in Springfield

Element by Marriott Springfield South

Cozy Central Home by CoxHealth & MSU - Fenced Yard

Comfortable Home Near CoxHealth & MSU - Fenced Yard

Frequently asked questions