Find hotels near Louisville Science Center, Louisville from AED 376

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15 Dec - 16 Dec
Tomorrow
16 Dec - 17 Dec
This weekend
19 Dec - 21 Dec
Next weekend
26 Dec - 28 Dec

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Our top choices for Louisville Science Center hotels

Free daily full breakfast
Market Street Inn

Market Street Inn

Market Street Inn
3.5 star property
2.1 km from Louisville Science Center
9.8 out of 10, Exceptional, (120)
"I enjoyed my stay, however the breakfast portion was very small even for a petite person like myself, I was still very hungry after breakfast. There was a cleaning issue with the bathroom that was overlooked by the cleaning staff that I alerted the owners to that will hopefully be fixed for future visitors. The house is great and very clean overall. The owners are very nice."
United States
Megan
The price is AED 680
AED 769 total
includes taxes & fees
16 Dec - 17 Dec
Market Street Inn
Front of property
DuPont Mansion Bed & Breakfast

DuPont Mansion Bed & Breakfast

DuPont Mansion Bed & Breakfast
3.0 star property
Old Louisville, 2.8 km from Louisville Science Center
9.8 out of 10, Exceptional, (97)
"Breakfast was wonderful, great place to stay!"
United States
Janie
The price is AED 493
AED 572 total
includes taxes & fees
16 Dec - 17 Dec
DuPont Mansion Bed & Breakfast
Exterior
Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
Downtown Louisville, 0.9 km from Louisville Science Center
9.6 out of 10, Exceptional, (428)
"Great location. Great restraunt, great staff. Pleasurable experience!"
United States
Harrison
The price is AED 643
AED 757 total
includes taxes & fees
29 Dec - 30 Dec
Hotel Distil, Autograph Collection
Signature Suite, 1 Queen Bed, Non Smoking | Premium bedding, down comforters, memory foam beds
Stellar Suites

Stellar Suites

Stellar Suites
4.5 star property
East Market District, 2.2 km from Louisville Science Center
9.6 out of 10, Exceptional, (117)
"Clean and great location "
United States
Greg
The price is AED 394
AED 650 total
includes taxes & fees
30 Dec - 31 Dec
Stellar Suites
Deluxe Single Room, 1 King Bed, River View | View from room
The Grady

The Grady

The Grady
4.0 star property
Downtown Louisville, 0.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1002)
"Room was great, Bed super comfy, staff was excellent, restaurant was awesome! Highly recommend!"
United States
Andrew
The price is AED 532
AED 626 total
includes taxes & fees
21 Dec - 22 Dec
The Grady
Dining
Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
Downtown Louisville, 1.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1005)
"All the staff we met were really nice! The rooms are clean and spacious."
United States
Kelly Anne
The price is AED 320
AED 376 total
includes taxes & fees
25 Dec - 26 Dec
Cambria Hotel Louisville Downtown-Whiskey Row
Lobby
The Brown Hotel

The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville, 1.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1154)
"I loved everything about this place"
United States
Steven
The Brown Hotel
2 restaurants, breakfast served
Tempo By Hilton Louisville Downtown Nulu

Tempo By Hilton Louisville Downtown Nulu

Tempo By Hilton Louisville Downtown Nulu
3.5 star property
Phoenix Hill, 2.1 km from Louisville Science Center
9.4 out of 10, Exceptional, (823)
"Love the hotel and will always stay there when visiting "
United States
Jeremy
The price is AED 377
AED 443 total
includes taxes & fees
4 Jan - 5 January 2026
Tempo By Hilton Louisville Downtown Nulu
Exterior detail
Central Park Bed & Breakfast

Central Park Bed & Breakfast

Central Park Bed & Breakfast
4.0 star property
Old Louisville, 3 km from Louisville Science Center
9.4 out of 10, Exceptional, (57)
"Our stay here was excellent in every way! The owners were very sweet and went out of their way to assist us in every way, the rooms were very cozy, and the breakfasts were fantastic. This is the best B&B we've ever stayed."
United States
John
The price is AED 476
AED 552 total
includes taxes & fees
15 Jan - 16 January 2026
Central Park Bed & Breakfast
Exterior
Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
Downtown Louisville, 0.2 km from Louisville Science Center
9.2 out of 10, Wonderful, (1005)
"The room was wonderful and the staff exceptional."
United States
Daniel
The price is AED 367
AED 432 total
includes taxes & fees
9 Jan - 10 January 2026
Homewood Suites by Hilton Louisville Downtown, KY
Front of property
21c Museum Hotel Louisville

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville, < 0.1 km from Louisville Science Center
9.2 out of 10, Wonderful, (1002)
"Staff was very kind, the art was fantastic, location was perfect to explore Whiskey Row, and we had a gorgeous room. Loved our time away there!"
United States
Tammy
The price is AED 511
AED 619 total
includes taxes & fees
1 Jan - 2 January 2026
21c Museum Hotel Louisville
Lobby
Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 0.3 km from Louisville Science Center
9.2 out of 10, Wonderful, (509)
"Great rooms "
United States
Ayden
The price is AED 356
AED 419 total
includes taxes & fees
4 Jan - 5 January 2026
Towneplace Suites By Marriott Louisville Downtown
Sauna, body treatments, aromatherapy, hot stone massages
Omni Louisville Hotel

Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
9.2 out of 10, Wonderful, (1735)
"This is a beautiful hotel in a great location. Very kind staff and helpful with directions."
United States
Bonnie
The price is AED 614
AED 723 total
includes taxes & fees
1 Jan - 2 January 2026
Omni Louisville Hotel
Bar (on property)
Moxy Louisville Downtown

Moxy Louisville Downtown

Moxy Louisville Downtown
3.5 star property
Downtown Louisville, 0.9 km from Louisville Science Center
9.2 out of 10, Wonderful, (698)
"Awesome location and the staff was super friendly"
United States
Kelly
The price is AED 356
AED 419 total
includes taxes & fees
28 Dec - 29 Dec
Moxy Louisville Downtown
Property amenity
AC Hotel Louisville Downtown

AC Hotel Louisville Downtown

AC Hotel Louisville Downtown
3.5 star property
East Market District, 2.1 km from Louisville Science Center
9.2 out of 10, Wonderful, (601)
"Loved the Hotel and area around the Hotel. Great shopping and restaurants"
United States
Melissa
The price is AED 346
AED 407 total
includes taxes & fees
26 Dec - 27 Dec
AC Hotel Louisville Downtown
Hypo-allergenic bedding, in-room safe, desk, laptop workspace
Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
4.0 star property
East Market District, 2.1 km from Louisville Science Center
9.2 out of 10, Wonderful, (1016)
"Nice hotel! "
United States
Stephanie
The price is AED 466
AED 549 total
includes taxes & fees
21 Dec - 22 Dec
Hotel Genevieve part of JdV by Hyatt
View from property
TownePlace Suites by Marriott Louisville North

TownePlace Suites by Marriott Louisville North

TownePlace Suites by Marriott Louisville North
3.0 star property
2.2 km from Louisville Science Center
9.2 out of 10, Wonderful, (640)
"Best hotel and staff ever "
United States
Cheryl
The price is AED 378
AED 427 total
includes taxes & fees
5 Jan - 6 January 2026
TownePlace Suites by Marriott Louisville North
4 restaurants, breakfast, lunch, dinner served; American cuisine
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville, 0.5 km from Louisville Science Center
9.0 out of 10, Wonderful, (3878)
"Beautiful room and great hospitality. "
United States
Chase
The price is AED 490
AED 576 total
includes taxes & fees
20 Dec - 21 Dec
Galt House Hotel Trademark Collection by Wyndham
Dinner served
Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
9.0 out of 10, Wonderful, (1115)
"Staff was courteous, hotel was beautiful and clean, and breakfast was amazing!"
United States
Shunskis
The price is AED 408
AED 481 total
includes taxes & fees
28 Dec - 29 Dec
Embassy Suites Louisville Downtown
View from room
Aloft Louisville Downtown

Aloft Louisville Downtown

Aloft Louisville Downtown
3.0 star property
Downtown Louisville, 0.9 km from Louisville Science Center
9.0 out of 10, Wonderful, (1005)
"Good"
United States
Les
The price is AED 369
AED 434 total
includes taxes & fees
24 Dec - 25 Dec
Aloft Louisville Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Louisville Science Center Hotel Reviews

Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG

10/10 Excellent
"Loved the shower: hot water, the glass curved door, stepping in a shower, not a tub, the high shower head, plenty of head room. The water pressure could have been harder. Our corner room was clean. Loved the full length mirror in the hallway. Not super quiet as our room faced the street, but we managed."
Linda 1-night trip
Posted 4 days ago
Holiday Inn Express & Suites Louisville Downtown by IHG

Hotels near other Louisville Science Center attractions

Louisville Slugger Museum showing interior views

Louisville Slugger Museum

4.5/5 (1,200 reviews)
You can spend an afternoon browsing the exhibits at Louisville Slugger Museum during your travels in Louisville. Amble around the area's riverfront or attend a sporting event.
See properties
Muhammad Ali Center featuring modern architecture and night scenes

Muhammad Ali Center

4.3/5 (298 reviews)
You can spend an afternoon studying the exhibits at Muhammad Ali Center during your trip to Louisville. Stroll along the area's riverfront or experience its acclaimed art scene.
See properties

Frequently asked questions

What's the area like around Louisville Science Center?
Louisville Science Center is located in an area of Louisville known for its beautiful river views, sporting events, and great live music scene. If you're looking for a convenient place to stay, check out the 291 hotels and other accommodations you'll find within a mile.
What's the best place to stay near Louisville Science Center?
Adjacent to Louisville Science Center, Holiday Inn Express & Suites Louisville Downtown by IHG is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a 24-hour fitness center. Other good choices within a short distance include Galt House Hotel Trademark Collection by Wyndham and Omni Louisville Hotel.
How many hotels can I expect to find close to Louisville Science Center?
Expedia has 291 hotels and other accommodations within a mile from Louisville Science Center.
If I need to cancel the hotel reservation for my stay near Louisville Science Center, will I receive a refund?
Yes, you'll find most hotel room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within a 24-hour period of booking. Add your dates and click on "Search", then filter by "fully refundable" to review the best deals near Louisville Science Center.
Where can I learn more about changing or cancelling my trip in the area near Louisville Science Center?
For more details about picking new dates or cancelling your stay near Louisville Science Center, click here.
What can I see and do near Louisville Science Center?
21c Museum Hotel, Louisville Slugger Museum, and Muhammad Ali Center feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like Belle of Louisville, Whiskey Row, and Thomas Edison House. You can catch a show at Kentucky Center for the Performing Arts, Louisville Palace, and Derby Dinner Playhouse.

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