Find hotels in Serra Mesa, San Diego from AED 281

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
13 Jul - 14 Jul
Tomorrow
14 Jul - 15 Jul
Next weekend
18 Jul - 20 Jul
In two weeks
25 Jul - 27 Jul

Filter by

Guest rating
Guest rating
Star rating

Discover 8,802 Serra Mesa hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Wyndham San Diego Bayside
Terrace/patio

Wyndham San Diego Bayside

4.0 star property
8.4 out of 10, Very Good, (5723)
"Fantastic property for the location and old school Hotel feel"
The price is AED 559
AED 754 total
includes taxes & fees
20 Jul - 21 Jul
Wyndham San Diego Bayside
Hard Rock Hotel San Diego
Outdoor pool

Hard Rock Hotel San Diego

4.0 star property
8.8 out of 10, Excellent, (2709)
"Great location, nice rooms, love the decor. "
The price is AED 685
AED 963 total
includes taxes & fees
3 Aug - 4 Aug
Hard Rock Hotel San Diego
Loews Coronado Bay Resort
Exterior

Loews Coronado Bay Resort

4.0 star property
8.8 out of 10, Excellent, (1007)
"Loved It! Very nice hotel and peaceful "
The price is AED 973
AED 1,251 total
includes taxes & fees
30 Jul - 31 Jul
Loews Coronado Bay Resort
Palihotel San Diego Gaslamp Quarter
Rooftop terrace

Palihotel San Diego Gaslamp Quarter

4.0 star property
8.6 out of 10, Excellent, (1511)
"Excellent hotel!"
The price is AED 364
AED 525 total
includes taxes & fees
7 Aug - 8 Aug
Palihotel San Diego Gaslamp Quarter
The Horton Grand, Downtown/Gaslamp Quarter
Serves dinner and happy hour

The Horton Grand, Downtown/Gaslamp Quarter

3.5 star property
9.0 out of 10, Wonderful, (2395)
"Love this hotel "
The Horton Grand, Downtown/Gaslamp Quarter
Best Western Plus Marina Gateway Hotel
Suite, 2 Queen Beds, Non Smoking, Refrigerator (with Sofabed) | Premium bedding, in-room safe, desk, laptop workspace

Best Western Plus Marina Gateway Hotel

3.5 star property
9.2 out of 10, Wonderful, (3134)
"This was our second time staying here and we loved it just as much as the first! Such a great hotel, friendly staff and a great location!"
The price is AED 625
AED 689 total
includes taxes & fees
3 Aug - 4 Aug
Best Western Plus Marina Gateway Hotel
Alma San Diego Downtown, a Tribute Portfolio Hotel
Premium Room, 1 King Bed, Balcony, City View | 1 bedroom, Frette Italian sheets, premium bedding, down comforters

Alma San Diego Downtown, a Tribute Portfolio Hotel

4.0 star property
9.0 out of 10, Wonderful, (676)
"Very nice and calm hotel. "
The price is AED 466
AED 686 total
includes taxes & fees
20 Jul - 21 Jul
Alma San Diego Downtown, a Tribute Portfolio Hotel
Gaslamp Plaza Suites
Lobby

Gaslamp Plaza Suites

3.5 star property
8.8 out of 10, Excellent, (1004)
"We enjoyed the roof top area and coffee for guest to have while enjoying the view."
The price is AED 511
AED 581 total
includes taxes & fees
21 Jul - 22 Jul
Gaslamp Plaza Suites
Legacy Resort Hotel & Spa
Garden

Legacy Resort Hotel & Spa

4.0 star property
9.2 out of 10, Wonderful, (2898)
"Great place to stay! "
The price is AED 539
AED 619 total
includes taxes & fees
11 Aug - 12 Aug
Legacy Resort Hotel & Spa
The Dana on Mission Bay
2 outdoor pools, a heated pool, sun loungers

The Dana on Mission Bay

3.5 star property
8.8 out of 10, Excellent, (3572)
"Great place to stay!"
The price is AED 790
AED 908 total
includes taxes & fees
10 Aug - 11 Aug
The Dana on Mission Bay
The Bristol Hotel San Diego
Property entrance

The Bristol Hotel San Diego

3.5 star property
8.4 out of 10, Very Good, (1331)
"Great location. Staff very attentive and friendly."
The Bristol Hotel San Diego
El Cordova Hotel on Coronado Island
Lobby

El Cordova Hotel on Coronado Island

3.5 star property
8.8 out of 10, Excellent, (1004)
"The best thing about this hotel is it is winin walking distance of the Hotel del Mar. The bathrooms are tiny, but it is worth it for the room prices."
The price is AED 958
AED 1,055 total
includes taxes & fees
15 Jul - 16 Jul
El Cordova Hotel on Coronado Island
The Sofia Hotel
Front of property

The Sofia Hotel

3.5 star property
8.4 out of 10, Very Good, (1490)
"Excellent stay in a great location"
The Sofia Hotel
La Pensione Hotel
Exterior

La Pensione Hotel

3.0 star property
8.6 out of 10, Excellent, (1778)
"Stayed here a few times, always a great getaway. "
La Pensione Hotel
Days Inn by Wyndham San Diego Hotel Circle
Outdoor pool, a heated pool

Days Inn by Wyndham San Diego Hotel Circle

3.0 star property
7.8 out of 10, Good, (2221)
"Great stay"
The price is AED 379
AED 436 total
includes taxes & fees
4 Aug - 5 Aug
Days Inn by Wyndham San Diego Hotel Circle
Sycuan Casino Resort
3 outdoor pools, cabanas (surcharge), pool umbrellas

Sycuan Casino Resort

4.0 star property
9.2 out of 10, Wonderful, (1386)
"Would recommend staying here "
Sycuan Casino Resort
Bay Club Hotel & Marina
Exterior

Bay Club Hotel & Marina

3.5 star property
9.0 out of 10, Wonderful, (2697)
"We loved our stay here. Great hotel. "
Bay Club Hotel & Marina
Staypineapple, Hotel Z, Gaslamp San Diego
Premium bedding, pillowtop beds, desk, blackout drapes

Staypineapple, Hotel Z, Gaslamp San Diego

3.0 star property
9.4 out of 10, Exceptional, (1006)
"Great location. Clean. Friendly and helpful staff. "
The price is AED 498
AED 683 total
includes taxes & fees
28 Jul - 29 Jul
Staypineapple, Hotel Z, Gaslamp San Diego
Urban Boutique Hotel
Check-in/check-out kiosk

Urban Boutique Hotel

3.0 star property
8.6 out of 10, Excellent, (1203)
"Nice hotel, good location, friendly and helpful staff "
The price is AED 559
AED 636 total
includes taxes & fees
27 Jul - 28 Jul
Urban Boutique Hotel
The Little Italy Hotel Downtown San Diego
1 bedroom, in-room safe, desk, blackout drapes

The Little Italy Hotel Downtown San Diego

4.0 star property
7.8 out of 10, Good, (1022)
"Great hotel"
The price is AED 438
AED 508 total
includes taxes & fees
4 Aug - 5 Aug
The Little Italy Hotel Downtown San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Serra Mesa

Find the best Serra Mesa areas and neighborhoods for the activities you enjoy most.
US Grant Hotel
Downtown San Diego map

Downtown San Diego

2 out of top 10 points of interest in this area

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

Belmont Park showing rides and a garden
Mission Beach map

Mission Beach

Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.

Pacific Beach Park showing a beach
Pacific Beach map

Pacific Beach

Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.

Gaslamp Quarter showing signage, night scenes and street scenes
Gaslamp Quarter map

Gaslamp Quarter

Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.

Ocean Beach
Ocean Beach map

Ocean Beach

Ocean Beach is known for its stunning beaches, and with sights like Ocean Beach Pier and Dog Beach, you won't get bored spending a day wandering around this part of San Diego.

Frequently asked questions

What's it like in Serra Mesa?

Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighborhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.

How many hotels will I be able to find in the Serra Mesa area?

Expedia has 36 hotels and other accommodations in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.

If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?

Yes, you'll find most hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Add your dates and click on "Search", then filter by "fully refundable" to view the top deals on offer in Serra Mesa.

Where can I learn more about changing or cancelling my trip to Serra Mesa?

For more information about picking new dates or cancelling your trip to Serra Mesa, click here.

What can I see and do in this San Diego neighborhood?

Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Convoy District and Old Cactus Garden are also worth a stop.