Find 5 Star Hotels in Lower Keys, FL

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Check availability on Lower Keys 5 Star Hotels

Tonight
7 Aug - 8 Aug
Tomorrow
8 Aug - 9 Aug
This weekend
8 Aug - 10 Aug
Next weekend
15 Aug - 17 Aug

Compare Lower Keys 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Lower Keys.
3-bedroom house in Lower Keys with Hot Tub, Sleeps 10+, Pet Freindly

3-bedroom house in Lower Keys with Hot Tub, Sleeps 10+, Pet Freindly

Big Pine Key
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Lower Keys

Explore the relaxing area of Lower Keys—parks, boating, and sights from Florida Keys Beaches to Sugarloaf Beach.

See all hotels in Lower Keys
Big Pine Key featuring a river or creek, a bay or harbor and general coastal views

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Frequently asked questions

How much does it cost to stay in a 5-star hotel in Lower Keys?
How much you pay for a 5-star hotel in Lower Keys can vary based on when you decide to travel and how long you plan to stay, among a number of factors. Use our price per night filter and other search tools to land the best rate on an indulgent stay.

  • Search for the lowest price per night

What makes a hotel 5 stars in Lower Keys?
Impeccable guest service is at the heart of every 5-star hotel in Lower Keys. From the minute you step through the door, staff ensure your every need is met, whether arranging valet parking or providing in-room massage treatments. Also, hotels must feature upscale amenities to qualify for a 5-star rating. These can include luxury bathrobes, saunas or spas, swimming pools, gastronomic kitchens and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in Lower Keys?
Expedia's filter tool is the quickest way to find exactly what you want. Select "5-star" and "All inclusive" to show the finest properties in Lower Keys where your lodging, meals, entertainment and activities are included in the price. At these stays, your vacation is pure leisure from the moment you pull up to the entrance.