Cape Girardeau Vacations

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Cape Girardeau Hotel Deals

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3351 Percy Drive Cape Girardeau MO
Fully refundableReserve now, pay when you stay
AED 367
AED 414 total
6 Sep - 7 Sep
includes taxes & fees
9.6/10 Exceptional! (1,003 reviews)
"Competitively priced. Complimentary happy hour and hot breakfast were exceptional. We stay at a Drury Inn whenever they are available."

Reviewed on 27 August 2026

Drury Plaza Hotel Cape Girardeau Conference Center
The Riverview

The Riverview

777 Main St Cape Girardeau MO
Fully refundableReserve now, pay when you stay
AED 390
AED 440 total
31 Aug - 1 Sep
includes taxes & fees
9.4/10 Exceptional! (647 reviews)
"Nice view of the river. The staff was nice."

Reviewed on 23 August 2026

The Riverview
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

3253 William Street Cape Girardeau MO
Fully refundable
AED 364
AED 410 total
27 Sep - 28 Sep
includes taxes & fees
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
See all 180 properties in Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Cape Girardeau attractions

A large, historic building with a dome and columns, surrounded by well-maintained lawns and trees.

Southeast Missouri State University

8.8/10 (248 reviews)
Take a campus tour or just explore the area of Southeast Missouri State University, during your trip to Cape Girardeau. While in this family-friendly area, you can savor the top-notch restaurants.
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A cable-stayed bridge over a river with a rocky shoreline in the foreground.

Riverfront Bridge Park

8.8/10 (129 reviews)
Enjoy panoramic views of the Mississippi River and Bill Emerson Memorial Bridge from this peaceful riverside park. Stroll along the well-maintained walking paths and find perfect spots for memorable photographs.
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Century Casino & Hotel Cape Girardeau

8.4/10 (176 reviews)
Why not roll the dice with a visit to Century Casino & Hotel Cape Girardeau during your travels in Cape Girardeau? While in this family-friendly area, you can savor the top-notch restaurants.
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Hunter Valley Winery

7.4/10 (48 reviews)
Sip award-winning Chambourcin and Chardonnay at this picturesque Missouri estate with lake views. Bring a picnic basket and enjoy live weekend music on the deck overlooking the sculpture garden.
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Riverfront Park

8.0/10 (2 reviews)
This riverside haven features terraced seating overlooking the Mississippi and a flood wall adorned with historical murals. Stroll the riverfront trail while watching paddle boats dock at this picturesque park.
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Show Me Center

8.6/10 (40 reviews)
The Show Me Center hosts Southeast Missouri State basketball and major concerts in a versatile arena setting. Catch Redhawks games or enjoy performances by renowned artists in this regional entertainment hub.
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Cape Splash Family Aquatic Center

8.6/10 (21 reviews)
This 3.5-acre water park thrills with a 265-foot free-fall slide and 700-foot lazy river. Families can splash in the pirate ship playground or relax in shaded lounge areas during summer months.
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Cape Rock Park

8.6/10 (36 reviews)
Perched on a limestone bluff, Cape Rock Park offers panoramic views of the Mississippi River and passing barges. Bring binoculars to spot wildlife at this historic former trading post.
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Frequently asked questions

How much does a Cape Girardeau vacation package cost?
You'll find cheap prices on Expedia for your Cape Girardeau getaway. However, a range of factors like your choice of hotel, the season and length of stay will influence how much your vacation to Cape Girardeau costs.
What are the cheapest months to go to Cape Girardeau?
You can typically find reduced prices and better availability in December, January and February. Explore our cheap Cape Girardeau vacation packages and you could score some great off-season deals.
How to find the best Cape Girardeau package deals?
Use Expedia's filter tool to help you find some of the best Cape Girardeau package deals. When you begin your search, just set your maximum budget and then sort the results by "Price: low to high." If you're looking to save, plan your adventure for midweek, or search for Cape Girardeau package deals in the off-peak season. Switch up your travel dates and you may land even better discounts. As a rule of thumb, it's typically best to lock in your vacation package as soon as possible.
Is it cheaper to book a Cape Girardeau vacation as a package?
An Expedia vacation package could score you significant savings when compared to arranging accommodations and flights separately. Better still, you can customize your Cape Girardeau getaway to match your exact needs. Pick your preferred flight time, select the hotel type and add a car rental. Browse our great deals to see how much you can save.
When to book a vacation package to Cape Girardeau?
If you have your Cape Girardeau vacation dates finalized, book early to score some outstanding deals. With Expedia, you can often reserve some flights up to a year in advance. Prefer spur-of-the-moment getaways? Our last-minute deals are great for traveling on a whim.
How to plan a trip to Cape Girardeau?
  1. Pick the right time to travel: Your schedule, preferred season and the type of weather you like can all impact your decision on when to visit Cape Girardeau.
  2. Set a budget: Factor in expenses like food, flights and transportation when calculating how much to set aside for your trip to Cape Girardeau. Then, select a hotel that matches your budget, whether that's an affordable option or a more luxurious getaway.
  3. Decide how long to go for: Now that you're up to speed on Cape Girardeau, you can work out the ideal length of your break. Create a draft plan and allocate enough time to get through everything on your must-do list.
  4. Combine your airfare and accommodations: After you've settled on your dates and duration, book the right Cape Girardeau vacation package for you.

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