Cape Girardeau Vacations

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Find the Best Cape Girardeau Vacation Packages

Cape Girardeau Hotel Deals

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive Cape Girardeau MO
Fully refundableReserve now, pay when you stay
The price is AED 367 per night from Feb 16 to Feb 17
AED 367
AED 414 total
16 Feb - 17 Feb
includes taxes & fees
9.4/10 Exceptional! (1,002 reviews)
The room was great. The facility was excellent. The people were excellent. Definitely going back.

Reviewed on 5 February 2026

Drury Plaza Hotel Cape Girardeau Conference Center
The Riverview

The Riverview

4 out of 5
777 Main St Cape Girardeau MO
Fully refundableReserve now, pay when you stay
The price is AED 325 per night from Feb 19 to Feb 20
AED 325
AED 367 total
19 Feb - 20 Feb
includes taxes & fees
9.4/10 Exceptional! (498 reviews)
The hotel was so nice! We planned this trip for my husbands 40th birthday, and I called ahead to see if they did anything for birthdays and they gave us a complementary upgrade on our room. I was taken back on that and thought it was so kind and generous. I wasn’t expecting that - I would have been ...

Reviewed on 1 February 2026

The Riverview
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

3 out of 5
3303 Campster Drive Cape Girardeau MO
Fully refundableReserve now, pay when you stay
The price is AED 331 per night from Feb 16 to Feb 17
AED 331
AED 373 total
16 Feb - 17 Feb
includes taxes & fees
9.4/10 Exceptional! (1,005 reviews)
From our room, to food; this was one of the best experiences that we’ve had with hotel travel. The breakfast rivaled a restaurant, the evening snacks and beverages were above board. The staff was friendly, the rooms were clean. The location is fantastic with Outback right beside the hotel and shopping ...

Reviewed on 8 February 2026

Drury Inn & Suites Cape Girardeau
See all 173 properties in Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Cape Girardeau

Panorama of Academic Hall, Southeast Missouri State University

Southeast Missouri State University

Take a campus tour or just explore the area of Southeast Missouri State University, during your trip to Cape Girardeau. While in this family-friendly area, you can savor the top-notch restaurants.

Southeast Missouri State University

Riverfront Park

Riverfront Park is just one of the places to see in Cape Girardeau, so why not enjoy the other things to explore during your travels? While in this family-friendly area, you can savor the top-notch restaurants.

Riverfront Park

Hunter Valley Winery

You can enjoy a tasting or tour at Hunter Valley Winery during your travels to Cape Girardeau. While in this family-friendly area, you can savor the top-notch restaurants.

Hunter Valley Winery

Frequently asked questions

How do I find cheap flights to Cape Girardeau that have flexible change policies?
At Expedia, we've been channeling our inner yoga master to offer you the most flexible fares around. Just mark the "No change fee" box directly underneath the "Flexible change policies" subheading to find the best flights to Cape Girardeau.
Which airlines fly to Cape Girardeau?
Organize your seat with Contour Aviation and then start piecing together your Cape Girardeau travel agenda. This top airline offers 52 flights each month to Cape Girardeau Municipal Airport (CGI), a central gateway.
How can I find cheap tickets to Cape Girardeau?
Book well ahead, fly with budget airlines, use points or miles — there are lots of ways! Another one is to use Expedia's "flexible dates" feature. Search for your Cape Girardeau flight, then check out the cheapest prices for nearby dates. In the last seven days, the lowest price for a flight to Cape Girardeau was .
How much is a flight to Cape Girardeau?
One-way flights departing from () sold for as low as in the last seven days. During this period, the price of a return ticket to Cape Girardeau ranged between and . If you spot a deal, book immediately — these prices don't wait around for long.
What are the most popular airports to fly into in Cape Girardeau?
Cape Girardeau Municipal Airport (CGI) is the main entryway for many eager to visit Cape Girardeau. Around 52 flights a month touch down here.
When is the cheapest time to fly to Cape Girardeau?
Jet off earlier in the week to nab the best airfare to Cape Girardeau. Tuesday is commonly the most economical day to take off, with Monday a close second. Saturday typically has the highest fares. This is because a lot of travelers choose to start their vacation on a weekend.
How much is a plane ticket to Cape Girardeau?
In the last seven days, fares to Cape Girardeau varied from to .
What months are the cheapest to book a flight to Cape Girardeau?
To score a bargain flight to Cape Girardeau, book during February when the price of tickets are at their cheapest. When's the most expensive time? In the USA, it's the festive month of December.