A forest with autumn foliage reflecting in a pond.

Search Vacation Homes in Mayfield Heights

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
16 Oct - 18 Oct
In two months
27 Nov - 29 Nov
In three months
25 Dec - 27 Dec
In four months
22 Jan - 24 Jan

Our top choices for Mayfield Heights vacation homes

Exterior detail

1. Lovely near Cleve Clinic/CWRU/UH - in Larchmere w/Porch!

Lovely near Cleve Clinic/CWRU/UH - in Larchmere w/Porch!
Buckeye-Shaker
9.4 out of 10, Exceptional, (102 reviews)
"This was a great choice for our trip to Cleveland. Communication was great, check in and out was easy, quiet area and no issues with parking! It was definitely perfect for our stay!"
United States
Amber D.
Lovely near Cleve Clinic/CWRU/UH - in Larchmere w/Porch!
A modern bedroom with a loft bed, a sofa, and a coffee table.

2. Modern Victorian Studio -Steps to Cleveland Clinic

Modern Victorian Studio -Steps to Cleveland Clinic
Hough
10.0 out of 10, Exceptional, (18 reviews)
"Great location near Cleveland Clinic. Very clean room with free parking onsite."
United States
Mike
The price is AED 312
AED 805 total
includes taxes & fees
25 Oct - 26 Oct
Modern Victorian Studio -Steps to Cleveland Clinic
A modern kitchen with dark cabinetry, a black countertop, and a coffee maker.

3. Large duplex king size bed and two queen size

Large duplex king size bed and two queen size
Cleveland Heights
9.0 out of 10, Wonderful, (82 reviews)
"The place was great, awesome, close to everything we needed. Thank you for a great place to stay. Plenty of room and bathrooms."
United States
Michelle T.
The price is AED 463
AED 721 total
includes taxes & fees
20 Oct - 21 Oct
Large duplex king size bed and two queen size
A dining room with a wooden table, six chairs, a chandelier, and a decorative mirror.

4. Charming 3-Bedroom Pet-Friendly Home by Lake Erie

Charming 3-Bedroom Pet-Friendly Home by Lake Erie
Euclid
10.0 out of 10, Exceptional, (9 reviews)
"The property was wonderful and we had a pleasant stay and would stay here again if in the area. "
United States
Terri V.
Charming 3-Bedroom Pet-Friendly Home by Lake Erie
A hallway with a white wall, a wooden floor, a white counter, and a chandelier.

5. Willow Woods Retreat - Farmhouse - Patio & Nature

Willow Woods Retreat - Farmhouse - Patio & Nature
Kirtland
9.2 out of 10, Wonderful, (42 reviews)
"We enjoyed our stay and the accommodations were as expected."
United States
Cherylee L.
Willow Woods Retreat - Farmhouse - Patio & Nature
A two-story house with a porch, a small front yard, and a visible front door.

6. Walk to Dining, Bars & Transit!

Walk to Dining, Bars & Transit!
Union-Miles Park
8.4 out of 10, Very good, (146 reviews)
"We came for my son’s graduation and had a great time. The location was centralized to everything we wanted to do. We would stay again."
United States
Chrissy W.
The price is AED 272
AED 878 total
includes taxes & fees
4 Oct - 5 Oct
Walk to Dining, Bars & Transit!
A bright kitchen with white cabinets, a wooden dining table, and chairs.

7. Luxury Downtown Townhome w/ Private Garage Unit 10

Luxury Downtown Townhome w/ Private Garage Unit 10
Downtown Cleveland
9.4 out of 10, Exceptional, (37 reviews)
"Had a great stay at this place. Came in to see the R&R Hall of fame and it couldn’t have been any easier/nicer. The place is spacious and very clean. It has all the modern amenities plus parking. If you’re looking for an upgraded, comfortable place to stay, this is it!"
United States
Martin
The price is AED 184
AED 634 total
includes taxes & fees
4 Oct - 5 Oct
Luxury Downtown Townhome w/ Private Garage Unit 10
A Roku TV on a wooden TV stand with a potted plant beside it.

8. Cozy 1bed 1bath near Airport, Cleveland Clinic, & Downtown CLE

Cozy 1bed 1bath near Airport, Cleveland Clinic, & Downtown CLE
Clark-Fulton
9.2 out of 10, Wonderful, (5 reviews)
"Place looks a lot better in photos than in actuality but all in all WAY better than any hotel. The parking situation is a bit dicey though and the door to the bathroom can use an upgrade."
United States
Mohammad B.
The price is AED 430
AED 503 total
includes taxes & fees
4 Oct - 5 Oct
Cozy 1bed 1bath near Airport, Cleveland Clinic, & Downtown CLE
A bustling street scene with brick buildings, outdoor seating, and string lights.

9. Chic 4 BR: Minutes to Cleveland Clinic, CWRU & UH!

Chic 4 BR: Minutes to Cleveland Clinic, CWRU & UH!
Glenville
9.4 out of 10, Exceptional, (12 reviews)
"Excellent stay. I will be back"
United States
Joe L.
The price is AED 730
AED 2,354 total
includes taxes & fees
4 Oct - 5 Oct
Chic 4 BR: Minutes to Cleveland Clinic, CWRU & UH!
A modern kitchen with white cabinets, stainless steel appliances, and a wooden floor.

10. Luxury Downtown Townhome w/ Private Garage Unit 13

Luxury Downtown Townhome w/ Private Garage Unit 13
Downtown Cleveland
9.6 out of 10, Exceptional, (122 reviews)
"Nice place"
United States
Matthew A.
The price is AED 184
AED 634 total
includes taxes & fees
5 Oct - 6 Oct
Luxury Downtown Townhome w/ Private Garage Unit 13
A modern kitchen with white cabinetry, a stainless steel stove, a microwave, and a refrigerator.

11. Soak and Play: Hot Tub + Family Arcade Fun

Soak and Play: Hot Tub + Family Arcade Fun
Euclid
10.0 out of 10, Exceptional, (5 reviews)
"Good accommodations and clear communication with the host. "
United States
Jared D.
Soak and Play: Hot Tub + Family Arcade Fun
A modern kitchen with stainless steel appliances, a wooden island with bar stools, and a brick accent wall.

12. Little Italy! Close to Cleveland Clinic, University Hospital & University Circle

Little Italy! Close to Cleveland Clinic, University Hospital & University Circle
University Circle
10.0 out of 10, Exceptional, (28 reviews)
"Very nice stay"
United States
Ryan W.
The price is AED 624
AED 1,126 total
includes taxes & fees
31 Oct - 1 Nov
Little Italy! Close to Cleveland Clinic, University Hospital & University Circle
A sign for Case Western Reserve University with a landscaped garden in front.

13. Colorful 4 BR in the Heart of University Circle!

Colorful 4 BR in the Heart of University Circle!
Glenville
10.0 out of 10, Exceptional, (6 reviews)
"Wonderful house, very roomy and the beds were amazing! "
United States
Julie H.
The price is AED 730
AED 2,354 total
includes taxes & fees
4 Oct - 5 Oct
Colorful 4 BR in the Heart of University Circle!
A modern living room with a large TV, blue armchairs, a coffee table, and a bookshelf.

14. Escape to Fun: Hot Tub & Game Arcade Retreat

Escape to Fun: Hot Tub & Game Arcade Retreat
Euclid
9.2 out of 10, Wonderful, (16 reviews)
"Our stay was excellent! The only suggestion I would offer is to consider providing a full size ironing board as the table top one provided is difficult to iron adult size clothes on."
United States
Tracie C.
The price is AED 618
AED 1,302 total
includes taxes & fees
15 Oct - 16 Oct
Escape to Fun: Hot Tub & Game Arcade Retreat
A dining area with a wooden table and chairs, a bench, and a view of the outdoors through large windows.

15. Luxury Downtown Townhome w/ Private Garage Unit 14

Luxury Downtown Townhome w/ Private Garage Unit 14
Downtown Cleveland
9.6 out of 10, Exceptional, (52 reviews)
"It was Everything I was expecting.!!!!!!Great stay!!"
United States
sara r.
The price is AED 735
AED 1,297 total
includes taxes & fees
31 Oct - 1 Nov
Luxury Downtown Townhome w/ Private Garage Unit 14
A bedroom with a bed, a fireplace, a chair, a dresser, and a window.

16. Steps to Cleveland Clinic - Bright Studio

Steps to Cleveland Clinic - Bright Studio
Hough
8.0 out of 10, Very good, (3 reviews)
"host was very nice and attentive !"
United States
Trinity D.
Steps to Cleveland Clinic - Bright Studio
A modern living room with a sectional sofa, a coffee table, a small table with a plant, and a floor lamp.

17. Amazing 2-bedroom house with AC in Eastlake

Amazing 2-bedroom house with AC in Eastlake
Eastlake
9.6 out of 10, Exceptional, (14 reviews)
"Clean pet friendly all we needed"
United States
Florine I.
The price is AED 1,377
AED 1,995 total
includes taxes & fees
31 Oct - 1 Nov
Amazing 2-bedroom house with AC in Eastlake
A crowded beach with people swimming and walking along the shore, a large blue archway, and buildings in the background.

18. Historic century home in Parma -oh so charming

Historic century home in Parma -oh so charming
Parma
9.8 out of 10, Exceptional, (59 reviews)
"Great location - very quiet. House very clean. Owner very responsive. Will stay again. "
United States
Todd M.
The price is AED 413
AED 835 total
includes taxes & fees
4 Oct - 5 Oct
Historic century home in Parma -oh so charming
A modern kitchen with a granite countertop, a built-in dishwasher, and a large window with curtains.

19. Historic Loft in the Heart of Downtown • Gym

Historic Loft in the Heart of Downtown • Gym
Downtown Cleveland
9.0 out of 10, Wonderful, (17 reviews)
"Nice place! Great location, would stay again."
United States
Yosef P.
The price is AED 234
AED 686 total
includes taxes & fees
4 Oct - 5 Oct
Historic Loft in the Heart of Downtown • Gym
A modern kitchen with white cabinets, a wooden countertop, and a built-in stove.

20. Unique BOHO Ohio City Loft Apt

Unique BOHO Ohio City Loft Apt
Ohio City
9.4 out of 10, Exceptional, (3 reviews)
"Excellent stay. Really nice place. Highly recommend!"
United States
Nicole P.
The price is AED 400
AED 836 total
includes taxes & fees
4 Oct - 5 Oct
Unique BOHO Ohio City Loft Apt
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Mayfield Heights Hotel Reviews

The Westin Cleveland Downtown

The Westin Cleveland Downtown

10/10 Excellent
"I loved my stay there. Helpful staff, nice looking property, comfortable bed and nice shower. I liked the lavender balm a lot. I would like to stay at the Westin again."
Yukari 1-night trip
Posted 6 hours ago
The Westin Cleveland Downtown

Explore a world of travel with Expedia