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Find Resorts & Hotels with Spas in Muscatine, IA

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Check availability on Muscatine Resorts & Hotels with Spas

This weekend
6 Nov - 8 Nov
Next weekend
13 Nov - 15 Nov

Our top choices for Muscatine hotels with a spa

A modern living room with a large painting, a sofa, two armchairs, a coffee table, and a view of a lake through large windows.

1. The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel

The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel
4.0 star property
Muscatine
9.6 out of 10, Exceptional, (311 reviews)
"I had an amazing stay and everything was clean. The staff were great and everything was awesome!"
United States
Brianna
The price is AED 547
AED 613 total
includes taxes & fees
20 Nov - 21 Nov
The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel
A hotel room with three beds, a desk, and a television.

2. Comfort Inn Muscatine near Hwy 61

Comfort Inn Muscatine near Hwy 61
2.5 star property
Muscatine
7.8 out of 10, Good, (263 reviews)
"The hotel is a few years old and has been well used but the current management obviously take a pride in maintaining the property and the services provided. Rooms are well appointed and clean and all areas very tidy inside and out. It is in a good location although on the outskirts of the city. Plenty dining options close by. Good breakfast included in the price."
United Kingdom
John
The price is AED 297
AED 332 total
includes taxes & fees
26 Nov - 27 Nov
Comfort Inn Muscatine near Hwy 61
A staircase with a metal railing, a display of books, and a door with an exit sign.

3. The Sage Hotel

The Sage Hotel
2.0 star property
Muscatine
6.8 out of 10, (102 reviews)
"Clean rooms staff is very nice"
United States
Micca
The price is AED 198
AED 222 total
includes taxes & fees
8 Nov - 9 Nov
The Sage Hotel
A modern lobby with a stone accent wall, comfortable seating, a reception desk, and a flat-screen TV.

4. Best Western Muscatine / Pearl City Hotel

Best Western Muscatine / Pearl City Hotel
2.5 star property
Muscatine
8.6 out of 10, Excellent, (561 reviews)
"Staff was very nice and helpful and accommodating and the overall motel was clean and easy to get around."
United States
Daniel
The price is AED 314
AED 352 total
includes taxes & fees
8 Nov - 9 Nov
Best Western Muscatine / Pearl City Hotel
A hotel dining area with wooden furniture, a stone accent wall, and a view of the outdoors.

5. Hampton Inn Muscatine

Hampton Inn Muscatine
2.5 star property
Muscatine
8.4 out of 10, Very good, (506 reviews)
"Hotel.staff was friendly. Renovations were being done while we were there but didnt interfere with our stay at all. Breakfast was good. Room was clean, bed was comfortable."
United States
CARRIE
The price is AED 358
AED 401 total
includes taxes & fees
12 Nov - 13 Nov
Hampton Inn Muscatine
A large indoor swimming pool with a wooden ceiling and large windows.

6. AmericInn by Wyndham Muscatine

AmericInn by Wyndham Muscatine
3.0 star property
Muscatine
7.6 out of 10, Good, (485 reviews)
"Absolutely love this place"
United States
Larry
The price is AED 328
AED 367 total
includes taxes & fees
12 Nov - 13 Nov
AmericInn by Wyndham Muscatine
Room

7. Strawberry Farm Bed & Breakfast

Strawberry Farm Bed & Breakfast
3.0 star property
Muscatine
9.4 out of 10, Exceptional, (32 reviews)
"Nice place, very nice people"
United States
Gail
The price is AED 595
AED 666 total
includes taxes & fees
6 Nov - 7 Nov
Strawberry Farm Bed & Breakfast
A compact kitchen with a built-in microwave, a stainless steel sink, and wooden cabinetry.

8. Super 8 by Wyndham Muscatine

Super 8 by Wyndham Muscatine
2.0 star property
Muscatine
6.4 out of 10, (299 reviews)
"Convenient, clean and quiet. Good breakfast and pleasant, helpful staff."
United States
Pamela
The price is AED 234
AED 262 total
includes taxes & fees
11 Nov - 12 Nov
Super 8 by Wyndham Muscatine
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Muscatine

Pool
Breakfast included

Top Muscatine Hotel Reviews

Rhythm City Casino Resort

Rhythm City Casino Resort

10/10 Excellent
"The bathroom with the shower was excellent."
John 1-night trip
Posted 8 hours ago
Rhythm City Casino Resort
Wyndham Moline on John Deere Commons

Wyndham Moline on John Deere Commons

10/10 Excellent
"The Wyndham was very nice. It was well maintained, clean and staff was very friendly. Ample parking. Close to restaurant and bars! I definitely would stay again!"
kim 1-night trip
Posted 10 hours ago
Wyndham Moline on John Deere Commons

Frequently asked questions

Looking for a spa hotel in Muscatine?
Book one of our fantastic spa hotels and treat yourself from the moment you arrive. Check out the theater scene and entertainment choices in Muscatine—your cultural tour starts here. Enjoy the churches and riverfront during your vacation. Hotels with spas are the perfect way to take a break from your routine and add a layer of luxury to your vacation.
What's there to see and do in Muscatine?
Experience Muscatine and visit Mississippi River, Wildcat Den State Park, and Cedar River. If you have some spare time during your trip, you might want to check out Riverside Park and Muscatine Art Center.
What is a Muscatine spa hotel?
Spa hotels in Muscatine provide lodging and have an on-site spa offering services including massages as well as beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.

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