Top Motels in New Madrid County in 2026

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Our top choices for New Madrid County motels

A hotel room with a large bed, two bedside lamps, a framed picture of a bridge, and a wooden nightstand with a phone.

1. Super 8 by Wyndham Charleston/Sikeston East MO

Charleston

William

AED 245 total

includes taxes & fees

15 Oct - 16 Oct

A hotel room with a bed, desk, chair, lamp, TV, and kitchenette.

2. New Orleans Inn Portageville

Portageville

Rachel

A hotel room with a dark wooden desk, a television, a lamp, a chair, and a mirror on the wall.

3. Reelfoot Lake Inn

Tiptonville

Danny

AED 231 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a bed, a desk, a chair, a bathroom with a bathtub, and a patterned floor.

4. Econo Lodge Dexter

Dexter

Herman

AED 212 total

includes taxes & fees

12 Nov - 13 Nov

A hotel room with two beds, a desk, a chair, a window with a view, and a painting on the wall.

5. Rockwood Inn Kennett I 55 Near Blytheville

Kennett

Terry

AED 257 total

includes taxes & fees

25 Oct - 26 Oct

A hotel room with two beds, a TV, a mirror, a wardrobe, and a desk.

6. OYO Hickory House Inn

Dexter

DIEGO

AED 250 total

includes taxes & fees

27 Oct - 28 Oct

A hotel room with two beds, a desk, a chair, a TV, and a mirror.

7. Country Yard Inn and Suite

Sikeston

AED 235 total

includes taxes & fees

15 Oct - 16 Oct

A hotel room with a large bed, a desk, a television, and a bathroom visible through an open door.

8. Eagle Inn Charleston

Charleston

Jackson

AED 271 total

includes taxes & fees

15 Oct - 16 Oct

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Top New Madrid County Hotel Reviews

Drury Inn & Suites Hayti Caruthersville

10/10 Excellent

"Seamless check-in and check-out. Reserved the room through Expedia only moments before stopping for the night. Everything in the room seemed cleaned and sanitized. The breakfast on Sunday morning was quite delicious before we got back on the road to home."

The Farmstead Hotel

8/10 Good

"I was in town for a high school class reunion, and the property was conveniently located, and the room rate was very competitive with other hotels in the area. On the positive side, the front desk staff was superb. Friendly and extremely helpful throughout my stay. The only negative? Checking out on Sunday morning, I had to go across the street to the "main" hotel and drop off my key. After check-out time, there should be a desk clerk at the Farmstead as well. My only complaint came during check-in on Friday afternoon. The front desk handed me my key and I went to the room. It looked fine, except for the pile of dirty towels behind the door. So, they sent me to another room--same thing. The third room proved to be the charm; clean, comfortable and no dirty towels behind the door. Overall, I was pleased with the stay. It more than met my needs, despite a few glitches."

Room 1

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for New Madrid County motels

1. Super 8 by Wyndham Charleston/Sikeston East MO

2. New Orleans Inn Portageville

3. Reelfoot Lake Inn

4. Econo Lodge Dexter

5. Rockwood Inn Kennett I 55 Near Blytheville

6. OYO Hickory House Inn

7. Country Yard Inn and Suite

8. Eagle Inn Charleston

Top New Madrid County Hotel Reviews

Drury Inn & Suites Hayti Caruthersville

Super 8 by Wyndham Sikeston/Miner Area

Drury Inn & Suites Sikeston, MO

Century Casino & Hotel Caruthersville

Reelfoot Lake Inn

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Holiday Inn Express & Suites Sikeston Southwest by IHG

Hampton Inn By Hilton Dexter

The Farmstead Hotel

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