Search Vacation Homes in San Luis Obispo Wine Country

  • Plan, book, stay with confidence

  • bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Check prices for these dates

Next weekend
In two weeks
In one month
In two months

Compare 804 Vacation Homes in San Luis Obispo Wine Country with updated reviews, rates, and availability.

LUXURY : VISTA HOUSE above the Clouds! Stunning view near Avila Beach & Downtown

10.0 out of 10, Exceptional, (444)
"Great view and nice spot!"
The price is AED 859
AED 1,385 total
includes taxes & fees
29 May - 30 May
LUXURY : VISTA HOUSE above the Clouds! Stunning view near Avila Beach & Downtown

Beach cottages, majestic Morro Bay

9.8 out of 10, Exceptional, (192)
"Our stay was great. Comfy beds, hot shower, well-stocked kitchen!"
Beach cottages, majestic Morro Bay

46W/Winery close, Bocce! Perfect for 1 couple, multi-adult, family! Dog Friendly

10.0 out of 10, Exceptional, (369)
"The location is great for being close to the wineries on the 46W. The farm animals added a unique touch and it was very peaceful and quiet at night. We will be back!"
46W/Winery close, Bocce! Perfect for 1 couple, multi-adult, family! Dog Friendly

Guesthouse on the Central Coast

9.8 out of 10, Exceptional, (25)
"It was a great place to get away and do nothing. My SIL and I enjoyed our stay very much. Thank you to our hosts. "
Guesthouse on the Central Coast

Iconic Modern Farmhouse- San Luis Obispo

9.8 out of 10, Exceptional, (26)
"We had a very enjoyable stay at the Modern Farmhouse while in town for CalPoly’s Family Weekend. "
The price is AED 1,006
AED 1,968 total
includes taxes & fees
2 Jun - 3 Jun
Iconic Modern Farmhouse- San Luis Obispo

Coastal VIEWS with easy SURF ACCESS. Home with yard and spa...pets considered!

10.0 out of 10, Exceptional, (128)
"Loved the view "
Coastal VIEWS with easy SURF ACCESS. Home with yard and spa...pets considered!

Beautiful Custom home, great ocean views! Pets Allowed!

10.0 out of 10, Exceptional, (211)
"Love this place and hosts were amazi.g. Will be back!"
Beautiful Custom home, great ocean views! Pets Allowed!

Pet friendly. 1 mi to beach. Not a house share.

9.8 out of 10, Exceptional, (209)
"So organized with instructions and code to get in to the place. That coffee was great!! So yummy!! Loved the patio area!!! Very lovely!!"
The price is AED 309
AED 511 total
includes taxes & fees
29 May - 30 May
Pet friendly. 1 mi to beach. Not a house share.

Gorgeous Home Near Pismo Beach & Wineries! Very Affordable!!!

9.4 out of 10, Exceptional, (158)
"They had everything we needed for a stay near family."
Gorgeous Home Near Pismo Beach & Wineries! Very Affordable!!!

Classic getaway by the sea within walking distance to everything w/ocean views

9.0 out of 10, Wonderful, (88)
"We had a wonderful time"
Classic getaway by the sea within walking distance to everything w/ocean views

The Boho Bungalow! Wine-Dine-Walk to downtown SLO

9.4 out of 10, Exceptional, (10)
"Beautiful and clean bungalow. It was perfect for us and our daughter. Walkable to downtown and the railroad station."
The price is AED 433
AED 966 total
includes taxes & fees
4 Jun - 5 Jun
The Boho Bungalow! Wine-Dine-Walk to downtown SLO

Welcome to Your Beach Retreat in Beautiful Pismodice!

10.0 out of 10, Exceptional, (134)
"We loved our stay, so cozy and comfortable. "
Welcome to Your Beach Retreat in Beautiful Pismodice!

Seaside! Steps to sand & minutes to dunes!

9.0 out of 10, Wonderful, (18)
"The overall stay was nice. The only issue was construction crews outside bedroom were loud until 10:30 pm, kept waking us all up. "
Seaside! Steps to sand & minutes to dunes!

BEACHFRONT with Spa

9.4 out of 10, Exceptional, (241)
"Everything was great with the place the view is amazing the neighborhood was very nice "
BEACHFRONT with Spa

We are Oceanfrontstays. - May Discounts, Mon-Thurs - SLEEPS 10 Sorry No Pets

9.6 out of 10, Exceptional, (118)
"This property was exactly as described, if not better! The back patio deck was perfect, large with no obstructing views. Our family spent more time visiting on the back deck enjoying the ocean view."
We are Oceanfrontstays. - May Discounts, Mon-Thurs - SLEEPS 10 Sorry No Pets

Lovely 3BR*One block to Beach!

10.0 out of 10, Exceptional, (14)
"Great property and location!"
Lovely 3BR*One block to Beach!

Beautiful ocean retreat

9.8 out of 10, Exceptional, (175)
"We really enjoyed our stay. This was our 2nd time booking this same location and is well worth it. Such a comfy place and was very close to downtown Morro Bay. "
Beautiful ocean retreat

Railroad Dist, 10 Walk to DT, 1 min Sally Loo's Sleeps 4/6 max, Pets & Parking

9.8 out of 10, Exceptional, (7)
"Check-in was easy & I loved how close DT SLO was and Sally Lou's for breakfast. "
The price is AED 729
AED 1,320 total
includes taxes & fees
1 Jun - 2 Jun
Railroad Dist, 10 Walk to DT, 1 min Sally Loo's Sleeps 4/6 max, Pets & Parking

Tropical Retreat. Great for 6-8 guest. Close to beaches.

2.0 star property
10.0 out of 10, Exceptional, (2)
"Amazing property in a great location. Friendly property managers. Great overall stay."
The price is AED 863
AED 1,594 total
includes taxes & fees
2 Jun - 3 Jun
Tropical Retreat. Great for 6-8 guest. Close to beaches.

Private Ranch House Resort

9.8 out of 10, Exceptional, (112)
"Had a great stay.....we would stay here again for sure!"
Private Ranch House Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in