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Compare 1,484 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Central Hotel Panama Casco Viejo
4.0 star property
9.2 out of 10, Wonderful, (1003)
"This Hotel is amazing! From the greetings at check in to the good bye at check out the staff were very attentive and amazing. The hotel has 4 restaurants each one with a different theme and food selection; we tried all and the food, prices, and staff were beyond of amazing. Hotel is in the center of Casco Viejo, very close to all attractions. Thank you the staff and I will definitely will recommend."
United States
Joel
The price is AED 725
AED 798 total
includes taxes & fees
4 Nov - 5 Nov
Central Hotel Panama Casco Viejo
La Concordia Boutique Hotel
4.0 star property
9.4 out of 10, Exceptional, (189)
"Clean, safety, nice staff, decoration and quite building "
United States
Claudia
The price is AED 725
AED 797 total
includes taxes & fees
16 Nov - 17 Nov
La Concordia Boutique Hotel
Hotel Coral Suites
3.5 star property
9.0 out of 10, Wonderful, (1008)
"This place is nice for a overnight stay"
United States
Gwendolyn
The price is AED 255
AED 280 total
includes taxes & fees
5 Nov - 6 Nov
Hotel Coral Suites
TRYP by Wyndham Panamá Centro
3.5 star property
9.2 out of 10, Wonderful, (1013)
"Staff was very friendly and breakfast option were wide"
United States
Sidoney
The price is AED 317
AED 349 total
includes taxes & fees
4 Nov - 5 Nov
TRYP by Wyndham Panamá Centro
Waldorf Astoria Panama
5.0 star property
9.0 out of 10, Wonderful, (1001)
"Great experience overall! "
United States
Reginald
The price is AED 639
AED 702 total
includes taxes & fees
1 Dec - 2 Dec
Waldorf Astoria Panama
Novotel Panama City
4.0 star property
9.2 out of 10, Wonderful, (1052)
"Room was always well attended to staff was very friendly and kind breakfast was gd 💕"
United States
Latoya
The price is AED 367
AED 404 total
includes taxes & fees
19 Nov - 20 Nov
Novotel Panama City
Principe Hotel and Suites
3.0 star property
9.0 out of 10, Wonderful, (1560)
"Clean from affordable pleasant staff was very nice stay "
United States
Iris
The price is AED 184
AED 202 total
includes taxes & fees
10 Nov - 11 Nov
Principe Hotel and Suites
Ramada Panama Centro Via Argentina
3.0 star property
7.4 out of 10, Good, (260)
"It was outdated, not a lot space for storage or counter space. Breakfast was really good."
United States
Amely
The price is AED 250
AED 275 total
includes taxes & fees
4 Nov - 5 Nov
Ramada Panama Centro Via Argentina
Bristol Panama, a Registry Collection Hotel
5.0 star property
9.2 out of 10, Wonderful, (1018)
"Lovely property "
United States
Arthur
The price is AED 716
AED 788 total
includes taxes & fees
3 Dec - 4 Dec
Bristol Panama, a Registry Collection Hotel
Hospedium Princess Hotel Panama
3.5 star property
7.6 out of 10, Good, (656)
"Breakfast was good "
United States
Cherries
The price is AED 189
AED 208 total
includes taxes & fees
5 Nov - 6 Nov
Hospedium Princess Hotel Panama
Gamboa Rainforest Reserve
3.5 star property
7.8 out of 10, Good, (650)
"Great hotel with many tours to enjoy the Rainforest"
United States
Christophe
The price is AED 341
AED 381 total
includes taxes & fees
4 Nov - 5 Nov
Gamboa Rainforest Reserve
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
9.6 out of 10, Exceptional, (621)
"great service"
United States
Gianluca
The price is AED 756
AED 832 total
includes taxes & fees
23 Nov - 24 Nov
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Aloft Panama
3.5 star property
8.6 out of 10, Excellent, (875)
"I didbt park ot had breakfast at the hotel"
United States
Karlene
The price is AED 430
AED 473 total
includes taxes & fees
10 Nov - 11 Nov
Aloft Panama
Courtyard by Marriott Panama Metromall
4.0 star property
8.8 out of 10, Excellent, (1004)
"Nice place right next door to the Metro Mall and a lot of great food options. "
United States
Chris
The price is AED 403
AED 443 total
includes taxes & fees
21 Nov - 22 Nov
Courtyard by Marriott Panama Metromall
Hotel Andros
3.0 star property
7.8 out of 10, Good, (144)
"This property was a "gem" in an otherwise ran down and dirty neighborhood."
United States
Daniel
The price is AED 125
AED 139 total
includes taxes & fees
6 Nov - 7 Nov
Hotel Andros
Plaza Paitilla Inn Hotel
3.5 star property
9.4 out of 10, Exceptional, (2127)
"great property and staff "
United States
Yunior
The price is AED 581
AED 639 total
includes taxes & fees
4 Nov - 5 Nov
Plaza Paitilla Inn Hotel
Hotel La Compañía Casco Antiguo
4.5 star property
9.8 out of 10, Exceptional, (240)
"Best place to stay in Panama City!"
United States
Stephen
The price is AED 1,140
AED 1,254 total
includes taxes & fees
24 Nov - 25 Nov
Hotel La Compañía Casco Antiguo
Courtyard by Marriott Panama Multiplaza Mall
4.0 star property
8.8 out of 10, Excellent, (1005)
"Good staff, near to the airport"
Mexico
Samuel Edmundo Villa
The price is AED 481
AED 529 total
includes taxes & fees
21 Nov - 22 Nov
Courtyard by Marriott Panama Multiplaza Mall
W Panama
5.0 star property
9.0 out of 10, Wonderful, (1002)
"Great hotel "
United States
Jasmine A
The price is AED 761
AED 837 total
includes taxes & fees
30 Nov - 1 Dec
W Panama
Hotel San Felipe
4.0 star property
9.4 out of 10, Exceptional, (223)
"Great Atmosphere! Love the rooftop bar."
United States
Andre Thanar
The price is AED 428
AED 471 total
includes taxes & fees
4 Nov - 5 Nov
Hotel San Felipe
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What's the best place for a stay in Santa Rosa?
Hotel Riu Plaza Panama, located 18.8 mi (30.2 km) from the heart of Santa Rosa, is a top choice for your stay based on our traveler data. Other good options for your stay in the area are Megapolis Hotel Panamá and Waldorf Astoria Panama. See all available top hotels, or vacation rentals in Santa Rosa.
What are some of the best vacation home rentals that Santa Rosa has to offer?
Panama View House – A Hilltop Retreat with Stunning Canal Views: This vacation home rental near Santa Rosa has air-conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings. See all vacation rentals in Santa Rosa.
If I need to cancel my hotel reservation in Santa Rosa, will I receive a refund?
Yes, most hotel bookings are fully refundable if cancelled prior to the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If you have a non-refundable reservation, you might be able to cancel it and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Rosa.
Where can I learn more about changing or cancelling my trip to Santa Rosa?
For more information about updating your trip to Santa Rosa or cancelling it, click here.
What is staying in Santa Rosa like?
Travelers to Santa Rosa will find plenty to explore and enjoy. A top sight in the area is Albrook Shopping Mall. In Santa Rosa, there are 2 hotels and other accommodations to choose from. Find out more about Santa Rosa.
What are the top places to visit in Santa Rosa?
A favorite place to visit is Chagres River. Additionally, you'll find Albrook Shopping Mall in the area. Check out what more to see and do in Expedia's Santa Rosa guide.
What's the seasonal weather like in Santa Rosa?
The hottest months are usually March and April with an average temp of 80°F, while the coldest months are January and February with an average of 79°F. The rainiest months in Santa Rosa are July, August, June, and November, with each month seeing an average of 15 inches of rainfall.

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