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Find Luxury Hotels in South San Francisco, CA

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Check availability on South San Francisco Luxury Hotels

Tonight
8 Dec - 9 Dec
Tomorrow
9 Dec - 10 Dec
This weekend
12 Dec - 14 Dec
Next weekend
19 Dec - 21 Dec

Top South San Francisco Luxury Hotels

View from property
AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront

AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront

4.0 star property
Oyster Point
9.2 out of 10, Wonderful, (1003)
"Very convenient stay for San Francisco. Clean hotel and very comfortable bed. Excellent gym. Will stay again. "
United States
Andy
The price is AED 453
AED 541 total
includes taxes & fees
21 Dec - 22 Dec
AC Hotel by Marriott San Francisco Airport Oyster Point/Waterfront
Bar (on property)
DoubleTree by Hilton San Francisco South Airport Blvd

DoubleTree by Hilton San Francisco South Airport Blvd

4.0 star property
South San Francisco
8.4 out of 10, Very Good, (2031)
"Room was very clean and front desk ladies were very friendly and helpful. "
United States
Carolyn
The price is AED 421
AED 497 total
includes taxes & fees
1 Jan - 2 January 2026
DoubleTree by Hilton San Francisco South Airport Blvd
Front of property - evening/night
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4.0 star property
Downtown San Francisco
8.6 out of 10, Excellent, (2104)
"Great stay "
United States
Samantha
The price is AED 343
AED 404 total
includes taxes & fees
21 Dec - 22 Dec
Hilton San Francisco Financial District
Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds
Hotel Caza Fisherman's Wharf

Hotel Caza Fisherman's Wharf

4.0 star property
Fisherman's Wharf
9.0 out of 10, Wonderful, (3831)
"We stay here a lot, great place and safe."
United States
Albert
The price is AED 426
AED 670 total
includes taxes & fees
14 Dec - 15 Dec
Hotel Caza Fisherman's Wharf
Terrace/patio
Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

4.0 star property
Downtown San Francisco
8.8 out of 10, Excellent, (2786)
"Great stay and clean hotel"
United States
LeoAngelo
The price is AED 368
AED 433 total
includes taxes & fees
14 Dec - 15 Dec
Club Quarters Hotel in San Francisco
Exterior
DoubleTree by Hilton Hotel Berkeley Marina

DoubleTree by Hilton Hotel Berkeley Marina

4.0 star property
Berkeley Marina
8.2 out of 10, Very Good, (3907)
"Great place to stay!"
United States
Rafael
The price is AED 436
AED 503 total
includes taxes & fees
15 Dec - 16 Dec
DoubleTree by Hilton Hotel Berkeley Marina
Reception
Oakland Marriott City Center

Oakland Marriott City Center

4.0 star property
Downtown Oakland
9.0 out of 10, Wonderful, (1005)
"Excellent stay! "
United States
Robert
The price is AED 408
AED 475 total
includes taxes & fees
28 Dec - 29 Dec
Oakland Marriott City Center
2 bars/lounges, cocktail bar
Timbri Hotel San Francisco, Curio Collection by Hilton

Timbri Hotel San Francisco, Curio Collection by Hilton

4.0 star property
Union Square
8.8 out of 10, Excellent, (908)
"Good location, clean room, very comfortable bed. Had issue with the parking but hotel staff responded promptly and corrected the issue. "
United States
James
The price is AED 389
AED 637 total
includes taxes & fees
22 Dec - 23 Dec
Timbri Hotel San Francisco, Curio Collection by Hilton
Interior entrance
Hotel Zoe Fisherman's Wharf

Hotel Zoe Fisherman's Wharf

4.0 star property
Fisherman's Wharf
9.2 out of 10, Wonderful, (1601)
"Great location and awesome hotel"
United States
Adam
The price is AED 372
AED 594 total
includes taxes & fees
22 Dec - 23 Dec
Hotel Zoe Fisherman's Wharf
Terrace/patio
Hyatt Centric Fisherman's Wharf San Francisco

Hyatt Centric Fisherman's Wharf San Francisco

4.0 star property
Fisherman's Wharf
8.6 out of 10, Excellent, (1471)
"Clean and great location "
United States
Shawn
The price is AED 434
AED 662 total
includes taxes & fees
14 Dec - 15 Dec
Hyatt Centric Fisherman's Wharf San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top South San Francisco Hotel Reviews

Hilton San Francisco Financial District

Hilton San Francisco Financial District

10/10 Excellent
"Great! The check was so quick and room was clean and comfortable. "
Nicole 1-night trip
Posted 1 day ago
Hilton San Francisco Financial District

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Frequently asked questions

Are you searching for a great accommodation for your luxury trip to South San Francisco?
Let Expedia help you arrange your flight to San Francisco Intl. Airport (SFO) airport or Oakland Intl. Airport (OAK) airport, and then choose from some places to stay that will deliver the luxury you seek. Amenities are important when you plan a vacation, so we make it easy to get what you'd like to make your stay special. If you want an upscale hotel that has fine dining, a spa, or several swimming pools, Expedia can assist you in finding the best luxury hotel experience that South San Francisco offers. During your visit, you might want to enjoy the sightseeing and tours which South San Francisco is known for.
When can I expect good weather in South San Francisco?
Planning for the weather is an important factor for making your trip to South San Francisco a success, especially when you're splurging. The hottest months are usually September and August with an average temp of 62°F, while the coldest months are February and January with an average of 53°F. Average annual precipitation for South San Francisco is 23 inches.
What's there to see and do in South San Francisco?
Take in some sights and attractions while you're in South San Francisco by visiting San Francisco Bay, Santa Cruz Mountains, and See's Candies. If you have spare time during your trip, you might want to make a stop at San Bruno Point Park and K1 Speed.
How can I get around South San Francisco?
It's easier to get around town in style when you know your options. Make your way to South San Francisco Metro Station to catch metro. To see more of the larger area, hop on a train at South San Francisco Station.