Photo by Jessica Richter
Find Resorts & Hotels with Spas in Southeast Missouri, MO
Check availability on Southeast Missouri Resorts & Hotels with Spas
Pick from 14 Southeast Missouri Resorts & Hotels with Spas and compare room rates, reviews, and availability. Most hotels are fully refundable.
Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MO
9.6 out of 10, Exceptional, (962)
The price is AED 413
AED 437 total
includes taxes & fees
30 Jun - 1 Jul
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center
9.6 out of 10, Exceptional, (1000)
The price is AED 413
AED 466 total
includes taxes & fees
5 Jun - 6 Jun
Drury Inn & Suites Hayti Caruthersville
Drury Inn & Suites Hayti Caruthersville
9.4 out of 10, Exceptional, (993)
The price is AED 413
AED 471 total
includes taxes & fees
6 Jun - 7 Jun
Holiday Inn Club Vacations Timber Creek Resort at De Soto, an IHG Hotel
Holiday Inn Club Vacations Timber Creek Resort at De Soto, an IHG Hotel
9.4 out of 10, Exceptional, (127)
The price is AED 657
AED 732 total
includes taxes & fees
19 Jun - 20 Jun
Drury Inn & Suites Poplar Bluff
Drury Inn & Suites Poplar Bluff
9.2 out of 10, Wonderful, (709)
The price is AED 380
AED 429 total
includes taxes & fees
9 Jun - 10 Jun
Crown Pointe Lodge, BW Signature Collection
Crown Pointe Lodge, BW Signature Collection
9.0 out of 10, Wonderful, (471)
The price is AED 426
AED 477 total
includes taxes & fees
12 Jun - 13 Jun
Hampton Inn Farmington
Hampton Inn Farmington
9.0 out of 10, Wonderful, (439)
The price is AED 541
AED 606 total
includes taxes & fees
22 Jun - 23 Jun
Auburn Place Hotel And Suites
Auburn Place Hotel And Suites
8.8 out of 10, Excellent, (1005)
The price is AED 244
AED 274 total
includes taxes & fees
6 Jun - 7 Jun
Super 8 by Wyndham Perryville
Super 8 by Wyndham Perryville
8.6 out of 10, Excellent, (743)
The price is AED 234
AED 263 total
includes taxes & fees
9 Jun - 10 Jun
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent reviews of Southeast Missouri hotelsExpedia verified reviews
5/5 Excellent
"Always a great place to stay. Staff is great, rooms are clean, breakfast is good, great family environment."
A verified traveler stayed at Auburn Place Hotel And Suites
Posted 2 days ago
Find More Hotels near Southeast Missouri
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- Luxury Hotels (12)
- Pet-friendly Hotels (48)
- Romantic Hotels (5)
- Shopping Hotels (29)
- Ski Hotels (1)
- Winery Hotels (7)
More Accommodation Types in Southeast Missouri
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- Apartments in Missouri (2,206)
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Hotels near popular Southeast Missouri Attractions
- Hotels near Johnson's Shut-ins State Park
- Hotels near Elephant Rocks State Park
- Hotels near Echo Bluff State Park
- Hotels near Ozark National Scenic Riverways
- Hotels near Southeast Missouri State University
- Hotels near Lake Wappapello
- Hotels near Big Spring
- Hotels near Alley Spring & Mill
- Hotels near Century Casino Caruthersville
- Hotels near Isle Casino Cape Girardeau
Southeast Missouri Hotels by Star Rating
Explore more hotels
- Super 8 by Wyndham Farmington
- Silo Farm Haus- located in the heart of wine country!
- Pear Tree Inn Cape Girardeau Near the Medical Center
- Pear Tree Inn Sikeston
- Fairfield Inn & Suites by Marriott Poplar Bluff
- Comfort Inn Festus - St Louis South
- Courtyard by Marriott Cape Girardeau Downtown
- Quality Inn
- Candlewood Suites Cape Girardeau, an IHG Hotel
- La Quinta Inn & Suites by Wyndham Festus - St. Louis South
- Best Western Plus Sikeston
- New Orleans Inn Portageville
- Comfort Suites Jackson-Cape Girardeau
- Drury Inn & Suites Poplar Bluff
- Hampton Inn Poplar Bluff
- The Farmstead Hotel
- Super 8 by Wyndham Perryville
- Town House Inn
- Travel Inn & Suites
- Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS, an IHG Hotel