Photo by Bill Dillard
Find 2 Star Hotels in Southeast Missouri, MO from AED 222
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Compare Southeast Missouri 2 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Baymont Inn and Suites by Wyndham Farmington, MO
Farmington
8.0 out of 10, Very Good, (1000)
The price is AED 197
AED 224 total
includes taxes & fees
5 Dec - 6 Dec

Motel 6 Poplar Bluff, MO
Poplar Bluff
7.8 out of 10, Good, (1002)
The price is AED 279
AED 294 total
includes taxes & fees
29 Nov - 30 Nov

Days Inn and Suites by Wyndham Sikeston
Sikeston
7.2 out of 10, Good, (1004)
The price is AED 231
AED 263 total
includes taxes & fees
21 Dec - 22 Dec

Pear Tree Inn Cape Girardeau West
Cape Girardeau
9.0 out of 10, Wonderful, (1002)
The price is AED 257
AED 290 total
includes taxes & fees
30 Nov - 1 Dec

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau
9.4 out of 10, Exceptional, (1002)
The price is AED 335
AED 378 total
includes taxes & fees
30 Nov - 1 Dec

Fairfield Inn & Suites by Marriott Poplar Bluff
Poplar Bluff
9.4 out of 10, Exceptional, (842)
The price is AED 382
AED 432 total
includes taxes & fees
1 Dec - 2 Dec

The Farmstead Hotel
Caruthersville
8.8 out of 10, Excellent, (450)
The price is AED 298
AED 338 total
includes taxes & fees
25 Nov - 26 Nov

Pear Tree Inn Cape Girardeau Near the Medical Center
Cape Girardeau
9.0 out of 10, Wonderful, (1001)
The price is AED 257
AED 290 total
includes taxes & fees
29 Nov - 30 Nov
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Explore similar 3-star hotels
Many 3-star hotels have the same amenities as 2-star hotels. See all 3-star hotels in Southeast Missouri.

Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive Cape Girardeau MO
The price is AED 331 per night from Dec 1 to Dec 2
AED 331
AED 373 total
1 Dec - 2 Dec
includes taxes & fees
9.4/10 Exceptional! (1,001 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Southeast Missouri
Explore the family-friendly area of Southeast Missouri—restaurants, wineries, and sights from Sam A. Baker State Park to Walnut Hollow Lake.

Photo by Bill Dillard
Open Photo by Bill Dillard
Top Southeast Missouri Hotel Reviews

Days Inn and Suites by Wyndham Sikeston
10/10 Excellent

Motel 6 Poplar Bluff, MO
10/10 Excellent
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Southeast Missouri Hotels by Star Rating
Hotels in Southeast Missouri Neighborhoods
Stay near popular Southeast Missouri attractions
- Hotels near Elephant Rocks State Park
- Hotels near Southeast Missouri State University
- Hotels near Johnson's Shut-ins State Park
- Hotels near Ozark National Scenic Riverways
- Hotels near Century Casino Caruthersville
- Hotels near Isle Casino Cape Girardeau
- Hotels near Lake Wappapello
- Hotels near Taum Sauk Mountain State Park
- Hotels near Alley Spring & Mill
- Hotels near Echo Bluff State Park
- Hotels near National Shrine of Our Lady of the Miraculous Medal
- Hotels near Current River State Park
- Hotels near Sainte Genevieve Winery
- Hotels near Rocky Falls
- Hotels near Riverfront Park
- Hotels near Bonne Terre Mine
- Hotels near Akers Ferry
- Hotels near Big Spring
- Hotels near Hawn State Park
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Explore more hotels
- Drury Inn & Suites Sikeston, MO
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