
Find 3 Star Hotels in Southeast Missouri, MO from AED 284
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check availability on Southeast Missouri 3 Star Hotels
Our top choices for Southeast Missouri 3-star hotels

1. Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.6 out of 10, Exceptional, (1,002 reviews)
The price is AED 345
AED 397 total
includes taxes & fees
15 Nov - 16 Nov

2. Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,005 reviews)
The price is AED 367
AED 414 total
includes taxes & fees
14 Nov - 15 Nov

3. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
8.8 out of 10, Excellent, (896 reviews)
The price is AED 293
AED 318 total
includes taxes & fees
15 Nov - 16 Nov

4. Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (242 reviews)
The price is AED 372
AED 419 total
includes taxes & fees
15 Nov - 16 Nov

5. Drury Inn & Suites Hayti Caruthersville
Drury Inn & Suites Hayti CaruthersvilleHayti
9.2 out of 10, Wonderful, (1,001 reviews)
The price is AED 360
AED 410 total
includes taxes & fees
15 Nov - 16 Nov

6. Drury Inn & Suites Poplar Bluff
Drury Inn & Suites Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (1,001 reviews)
The price is AED 331
AED 373 total
includes taxes & fees
15 Nov - 16 Nov

7. Holiday Inn Poplar Bluff by IHG
Holiday Inn Poplar Bluff by IHGPoplar Bluff
8.8 out of 10, Excellent, (806 reviews)
The price is AED 290
AED 328 total
includes taxes & fees
11 Dec - 12 Dec

8. Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (1,002 reviews)
The price is AED 331
AED 373 total
includes taxes & fees
14 Nov - 15 Nov

9. Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
9.6 out of 10, Exceptional, (1,003 reviews)
The price is AED 294
AED 311 total
includes taxes & fees
22 Nov - 23 Nov

10. La Quinta Inn & Suites by Wyndham Festus - St. Louis South
La Quinta Inn & Suites by Wyndham Festus - St. Louis SouthFestus
7.8 out of 10, Good, (1,006 reviews)
The price is AED 309
AED 353 total
includes taxes & fees
15 Nov - 16 Nov

11. Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau DowntownCape Girardeau
9.6 out of 10, Exceptional, (559 reviews)
The price is AED 426
AED 483 total
includes taxes & fees
22 Nov - 23 Nov

12. Century Casino & Hotel Caruthersville
Century Casino & Hotel CaruthersvilleCaruthersville
8.6 out of 10, Excellent, (204 reviews)
The price is AED 446
AED 508 total
includes taxes & fees
11 Nov - 12 Nov

13. Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (978 reviews)
The price is AED 356
AED 402 total
includes taxes & fees
22 Nov - 23 Nov

14. Honeysuckle Inn - Mountain View
Honeysuckle Inn - Mountain ViewMountain View
8.4 out of 10, Very good, (409 reviews)
The price is AED 349
AED 378 total
includes taxes & fees
11 Dec - 12 Dec

15. Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
9.4 out of 10, Exceptional, (118 reviews)
The price is AED 404
AED 459 total
includes taxes & fees
19 Nov - 20 Nov

16. Current River Inn
Current River InnVan Buren
8.2 out of 10, Very good, (224 reviews)
The price is AED 400
AED 433 total
includes taxes & fees
11 Nov - 12 Nov

17. Baymont by Wyndham Festus
Baymont by Wyndham FestusFestus
6.8 out of 10, (1,002 reviews)
The price is AED 248
AED 284 total
includes taxes & fees
11 Dec - 12 Dec

18. TownePlace Suites by Marriott Sikeston
TownePlace Suites by Marriott SikestonSikeston
9.2 out of 10, Wonderful, (31 reviews)
The price is AED 400
AED 455 total
includes taxes & fees
19 Nov - 20 Nov

19. Johnson's Shut-ins State Park
Johnson's Shut-ins State ParkMiddle Brook
10.0 out of 10, Exceptional, (3 reviews)

20. Urban Lofts
Urban LoftsPerryville
9.4 out of 10, Exceptional, (22 reviews)
The price is AED 740
AED 1,142 total
includes taxes & fees
11 Nov - 12 Nov
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 4-star hotels
Many 4-star hotels have the same amenities as 3-star hotels. See all 4-star hotels in Southeast Missouri.

The Riverview
777 Main St Cape Girardeau MO
The price is AED 403 per night from Nov 12 to Nov 13
AED 403
AED 455 total
12 Nov - 13 Nov
includes taxes & fees
Still don't see what you're looking for?
See all properties in Southeast Missouri.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Southeast Missouri
Explore the family-friendly area of Southeast Missouri—restaurants, wineries, and sights from K Bridge Recreation Area to Lake Wappapello State Park.

Photo by Bill Dillard
Open Photo by Bill Dillard
Top Southeast Missouri Hotel Reviews

Drury Inn & Suites Jackson MO
10/10 Excellent
Frequently asked questions
Explore a world of travel with Expedia
- Wyndham Hotels in Doe Run
- B&B in Ironton
- Wyndham Hotels in Caledonia
- 2 Star Hotels in Pilot Knob
- Wyndham Hotels in Pilot Knob
- Vacation Homes in Southeast Missouri
- 5 Star Hotels in Bonne Terre
- 4 Star Hotels in Ellington
- Cottages in Caledonia
- Hotels with WiFi in Pilot Knob
- Hotels near Bollinger Mill State Historic Site
- 4 Star Hotels in Fredericktown
- Motels in Van Buren
- 3 Star Hotels in Friedheim
- 4 Star Hotels in Leadwood
- Hotels with Free Parking in Farmington
- 2 Star Hotels in Piedmont
- Cabin Rentals in Southeast Missouri
- 5 Star Hotels in Friedheim
- 2 Star Hotels in Poplar Bluff
- Wyndham Hotels in Friedheim
- Wyndham Hotels in Park Hills
- 4 Star Hotels in Bloomfield
- 4 Star Hotels in Poplar Bluff
- 5 Star Hotels in Flat River
- Hilton Hotels in Belleview
- 5 Star Hotels in Middle Brook
- 4 Star Hotels in Piedmont
- Motels in Doe Run
- Hotels near Fort Davidson State Historic Site
- Winery Hotels in Southeast Missouri
- Farmstay in Sedgewickville
- Cabin Rentals in Belleview
- Vacation Homes in Friedheim
- 3 Star Hotels in Poplar Bluff
- Apartments in Lesterville
- Wyndham Hotels in Sedgewickville
- Cottages in Ironton
- Hilton Hotels in Arcadia
- Hotels with Hot Tubs in Southeast Missouri
- Premier Inn Hotels in Park Hills
- 5 Star Hotels in Ironton
- Resorts & Hotels with Spas in Farmington
- Cottages in Doe Run
- 2 Star Hotels in Park Hills
- 5 Star Hotels in Piedmont
- Rv Parks in Southeast Missouri
- Vacation Homes in Piedmont
- Independent Hotels in Friedheim
- 2 Star Hotels in Black
- Cabin Rentals in Farmington
- Wyndham Hotels in Fredericktown
- 2 Star Hotels in Sturdivant
- Middle Brook Hotels
- Vacation Homes in Leadwood
- 5 Star Hotels in Van Buren
- Cabin Rentals in Friedheim
- 2 Star Hotels in Lowndes
- La Quinta Inn & Suites Hotels in Southeast Missouri
- Hotels near Twin Oaks Vineyard & Winery
- Aimbridge Hospitality Hotels in Wappapello
- 3 Star Hotels in Pilot Knob
- Hotels with Bars in Farmington
- Pet-Friendly Hotels in Southeast Missouri
- Motels in Ironton
- 4 Star Hotels in Doe Run
- Farmstay in Ellington
- Marriott Hotels & Resorts in Farmington
- Pilot Knob Hotels
- Golf Hotels in Southeast Missouri
- Farmington Hotels
- Vacation Homes in Sturdivant
- 2 Star Hotels in Lesterville
- Motels in Fredericktown
- Motels in Ellington
- 2 Star Hotels in Perryville
- Apartments in Piedmont
- 3 Star Hotels in Bloomfield
- 4 Star Hotels in Jackson
- Motels in Park Hills
- Independent Hotels in Marble Hill
- 2 Star Hotels in Fredericktown
- Cabin Rentals in Park Hills
- 5 Star Hotels in Arcadia
- Flights from Farmington
- Flights to Black
- Flights from Lesterville
- Flights from Leadwood
- Flights from Ellington
- Flights from Ironton
- Flights from Desloge
- Flights from Caledonia
- Flights from Park Hills
- Flights from Annapolis
- Flights from Van Buren
- Flights from Pilot Knob
- Flights from Fredericktown
- Flights from Flat River
- Flights from Lowndes
































































