Find 4 Star Hotels in St. Charles, MO from AED 382
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Compare St. Charles 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Downtown St. Louis
8.8 out of 10, Excellent, (1145)
The price is AED 371
AED 441 total
includes taxes & fees
8 Dec - 9 Dec

Hyatt Regency St. Louis at The Arch
Downtown St. Louis
8.4 out of 10, Very Good, (3996)
The price is AED 347
AED 409 total
includes taxes & fees
21 Dec - 22 Dec

Hilton St. Louis Frontenac
Frontenac
8.8 out of 10, Excellent, (1001)
The price is AED 395
AED 460 total
includes taxes & fees
20 Dec - 21 Dec

21C Museum Hotel St Louis
Downtown West
9.0 out of 10, Wonderful, (1478)
The price is AED 559
AED 672 total
includes taxes & fees
28 Dec - 29 Dec

The Cheshire
Richmond Heights
8.6 out of 10, Excellent, (1000)
The price is AED 473
AED 562 total
includes taxes & fees
7 Dec - 8 Dec

Renaissance St. Louis Airport Hotel
Berkeley
8.4 out of 10, Very Good, (1050)
The price is AED 433
AED 507 total
includes taxes & fees
19 Dec - 20 Dec

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Grand Center
8.8 out of 10, Excellent, (1030)
The price is AED 352
AED 416 total
includes taxes & fees
7 Dec - 8 Dec

Live by Loews - St.Louis
Downtown St. Louis
9.4 out of 10, Exceptional, (1105)
The price is AED 547
AED 651 total
includes taxes & fees
7 Dec - 8 Dec
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Explore similar 5-star hotels
Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in St. Charles.

Four Seasons Hotel St Louis
999 North Second Street St. Louis MO
The price is AED 1,524 per night from Jan 1 to Jan 2
AED 1,524
AED 1,782 total
1 Jan - 2 January 2026
includes taxes & fees
9.4/10 Exceptional! (1,006 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about St. Charles
Stroll down Historic Main Street, where 1812-era charm meets modern boutiques and eateries. Bike the scenic Katy Trail or try your luck at Ameristar Casino before exploring the Lewis & Clark Boathouse.

Top St. Charles Hotel Reviews

Hyatt Regency St. Louis at The Arch
10/10 Excellent
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St. Charles Hotels by Star Rating
Hotels in St. Charles Neighborhoods
Stay near popular St. Charles attractions
- Hotels near Ameristar Casino St. Charles
- Hotels near St Charles Convention Center
- Hotels near Lindenwood University
- Hotels near Historic Main Street
- Hotels near Family Arena
- Hotels near Fast Lane Classic Cars
- Hotels near Katy Trail
- Hotels near Missouri Bluffs Golf Course
- Hotels near Lewis & Clark Boathouse and Nature Center
- Hotels near First Missouri State Capitol Historic Site
- Hotels near Weldon Spring Site Interpretive Center
- Hotels near Jaycee Park
- Hotels near Frenchtown Heritage Museum
- Hotels near Missouri Artists on Main
- Hotels near Mississippi River
- Hotels near Missouri River
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Explore more hotels
- 21C Museum Hotel St Louis
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- Drury Inn & Suites St. Louis Union Station
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