Find hotels in Otay Mesa, San Diego from AED 242

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Our top choices for Otay Mesa hotels

Quality Suites San Diego Otay Mesa

Quality Suites San Diego Otay Mesa
2.5 star property
Otay Mesa
7.2 out of 10, Good, (1006)
"Beautiful place "
United States
Joe
The price is AED 387
AED 441 total
includes taxes & fees
21 Dec - 22 Dec
Quality Suites San Diego Otay Mesa

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2.5 star property
Otay Mesa
8.0 out of 10, Very Good, (1561)
"Great place to stay. Really clean and helpful staff "
United States
Zulma
The price is AED 437
AED 497 total
includes taxes & fees
21 Dec - 22 Dec
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
Gaslamp Quarter, 24.2 km from Otay Mesa
9.4 out of 10, Exceptional, (1003)
"Great location "
United States
Mohammad
The price is AED 324
AED 481 total
includes taxes & fees
17 Dec - 18 Dec
Staypineapple, Hotel Z, Gaslamp San Diego

Berkshire Motor Hotel

Berkshire Motor Hotel
2.5 star property
North Park, 26.7 km from Otay Mesa
8.4 out of 10, Very Good, (1002)
"Amazing friendly staff"
United States
Jonathan
The price is AED 314
AED 354 total
includes taxes & fees
16 Dec - 17 Dec
Berkshire Motor Hotel

Westgate Hotel

Westgate Hotel
4.5 star property
24.9 km from Otay Mesa
9.0 out of 10, Wonderful, (1006)
"Everything about the Hotel including staff was fantastic"
Canada
Donna
Westgate Hotel

Old Town Western Inn & Suites

Old Town Western Inn & Suites
2.5 star property
Old Town San Diego, 29.6 km from Otay Mesa
7.6 out of 10, Good, (1007)
"Friendly staff and clean rooms"
United States
Lola
The price is AED 465
AED 524 total
includes taxes & fees
4 Jan - 5 January 2026
Old Town Western Inn & Suites

Courtyard by Marriott Old Town

Courtyard by Marriott Old Town
3.0 star property
Old Town San Diego, 29.7 km from Otay Mesa
8.6 out of 10, Excellent, (1004)
"All around great stay "
United States
Chasity
The price is AED 408
AED 469 total
includes taxes & fees
25 Dec - 26 Dec
Courtyard by Marriott Old Town

Ash&9th

Ash&9th
2.0 star property
24.7 km from Otay Mesa
8.0 out of 10, Very Good, (169)
"great place to stay "
United States
Fernando L
The price is AED 278
AED 316 total
includes taxes & fees
16 Dec - 17 Dec
Ash&9th

Ocean Villa Inn

Ocean Villa Inn
2.5 star property
Ocean Beach, 33.7 km from Otay Mesa
8.0 out of 10, Very Good, (1136)
"Fantastic location!"
United States
Lydia
Ocean Villa Inn

La Pensione Hotel

La Pensione Hotel
3.0 star property
Little Italy, 25.8 km from Otay Mesa
8.6 out of 10, Excellent, (1912)
"Great check-in experience, convenient parking, the room was clean and bed was comfortable. The city view option was exceptionally pleasant. Will stay again! "
United States
Mike
La Pensione Hotel

Fairfield Inn & Suites San Diego Old Town

Fairfield Inn & Suites San Diego Old Town
2.5 star property
Old Town San Diego, 29.4 km from Otay Mesa
8.8 out of 10, Excellent, (1005)
"Rooms are nice, hotel is in a good area "
United States
Maria
The price is AED 408
AED 469 total
includes taxes & fees
22 Dec - 23 Dec
Fairfield Inn & Suites San Diego Old Town

Sea Harbor Hotel

Sea Harbor Hotel
2.0 star property
30.1 km from Otay Mesa
8.6 out of 10, Excellent, (1004)
"Great stay"
United States
Naomi
Sea Harbor Hotel

Homewood Suites by Hilton San Diego Mission Valley/Zoo

Homewood Suites by Hilton San Diego Mission Valley/Zoo
3.0 star property
28.5 km from Otay Mesa
8.4 out of 10, Very Good, (1004)
"Breakfast and manager reception was great."
United States
Chetan
The price is AED 423
AED 486 total
includes taxes & fees
4 Jan - 5 January 2026
Homewood Suites by Hilton San Diego Mission Valley/Zoo

Heritage Inn San Diego

Heritage Inn San Diego
2.0 star property
31.8 km from Otay Mesa
7.4 out of 10, Good, (1162)
"Clean room, great location "
United States
Benjamin
The price is AED 211
AED 242 total
includes taxes & fees
28 Dec - 29 Dec
Heritage Inn San Diego

Hilton Garden Inn San Diego Old Town/SeaWorld Area

Hilton Garden Inn San Diego Old Town/SeaWorld Area
3.0 star property
Old Town San Diego, 30.5 km from Otay Mesa
8.6 out of 10, Excellent, (1294)
"Very nice hotel"
United States
Krist
The price is AED 438
AED 503 total
includes taxes & fees
29 Dec - 30 Dec
Hilton Garden Inn San Diego Old Town/SeaWorld Area

Urban Boutique Hotel

Urban Boutique Hotel
3.0 star property
Little Italy, 25.7 km from Otay Mesa
8.6 out of 10, Excellent, (1269)
"Locations is excellent and the front desk lady was friendly "
Canada
Ju
Urban Boutique Hotel

The Beau Downtown San Diego Gaslamp Quar

The Beau Downtown San Diego Gaslamp Quar
3.0 star property
Gaslamp Quarter, 24.5 km from Otay Mesa
8.8 out of 10, Excellent, (556)
"beautiful hotel, well maintained facilities, convenient location, very kind staff"
United States
Sergio
The price is AED 445
AED 506 total
includes taxes & fees
16 Dec - 17 Dec
The Beau Downtown San Diego Gaslamp Quar

Margaritaville Hotel San Diego Gaslamp Quarter

Margaritaville Hotel San Diego Gaslamp Quarter
4.0 star property
Gaslamp Quarter, 24.1 km from Otay Mesa
9.0 out of 10, Wonderful, (1163)
"Amenities and location were great. "
United States
Julie
The price is AED 559
AED 797 total
includes taxes & fees
16 Dec - 17 Dec
Margaritaville Hotel San Diego Gaslamp Quarter

Gaslamp Plaza Suites

Gaslamp Plaza Suites
3.5 star property
Gaslamp Quarter, 24.6 km from Otay Mesa
9.0 out of 10, Wonderful, (1014)
"Yes everything was great I will stay there again."
United States
Sergio
The price is AED 437
AED 497 total
includes taxes & fees
16 Dec - 17 Dec
Gaslamp Plaza Suites

The Westin San Diego Bayview

The Westin San Diego Bayview
4.0 star property
25.2 km from Otay Mesa
8.6 out of 10, Excellent, (1064)
"I loved the hotel rooms bar area jacuzzi area everything was great it was in a pretty location will definitely come back "
United States
Alliyah
The price is AED 497
AED 682 total
includes taxes & fees
21 Dec - 22 Dec
The Westin San Diego Bayview
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Otay Mesa

Find the best Otay Mesa areas and neighborhoods for the activities you enjoy most.

Downtown San Diego

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

Gaslamp Quarter

Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.

Pacific Beach

Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.

Mission Beach

Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.

Ocean Beach

Ocean Beach is known for its stunning beaches, and with sights like Ocean Beach Pier and Dog Beach, you won't get bored spending a day wandering around this part of San Diego.

Top Otay Mesa Hotel Reviews

Find out more about Otay Mesa

Top reasons to visit Otay Mesa

  • Family-Friendly Attractions: Otay Mesa offers a range of activities perfect for families, including shopping centers, theaters, and a water park.
  • Vibrant Cultural Events: Exciting events like Comic-Con and various local festivals create a lively atmosphere for visitors.
  • Diverse Outdoor Activities: Nearby Mission Bay provides scenic views and opportunities for outdoor adventures.
  • Convenient Shopping and Dining: The Otay Town Center Mall features a variety of shopping and dining options for all tastes.
  • Variety of Accommodations: Otay Mesa offers diverse lodging options, catering to families, couples, and budget travelers.

Find great hotels near Otay Mesa

Otay Mesa offers a diverse selection of accommodations, catering to various preferences and budgets. From comfortable hotels to charming guesthouses, you'll find options that are perfect for pet owners, business travelers, and families alike. Whether you're seeking the best-rated hotels, affordable stays, or reviews to guide your choice, Otay Mesa has something to make your visit enjoyable and memorable.

  • Best Western Plus Marina Gateway Hotel: This welcoming hotel is perfect for families and pet lovers seeking a memorable vacation experience. Situated 17.7km from Otay Mesa, the Best Western Plus Marina Gateway Hotel offers a delightful blend of comfort and inclusivity, proudly catering to LGBTQIA travelers. Families will appreciate the child-friendly amenities, including a mini-golf course, children's pool, and free cribs. Additionally, the hotel’s pet policy allows for dogs onsite, ensuring that your furry friends are part of your getaway.
  • Ramada by Wyndham San Diego National City: Ideal for business travelers and adventure seekers, the Ramada by Wyndham San Diego National City is located 17.7km from Otay Mesa. This 3-star hotel boasts a variety of recreation options that include nearby boat tours, surfing, and hiking, making it a fantastic choice for those looking to blend work with play. Families will find conveniences like free cribs, ensuring a comfortable stay for younger guests. Enjoy a balanced mix of relaxation and excitement at this versatile property.
  • Hard Rock Hotel San Diego: Located 24.1km from Otay Mesa, the Hard Rock Hotel San Diego offers a vibrant atmosphere for adventure enthusiasts and LGBTQIA travelers alike. This 4-star hotel is renowned for its exciting recreation opportunities, including nearby water sports and rentals for bicycles and scooters. Guests can indulge in a lively experience while enjoying stylish accommodations. The hotel's commitment to inclusivity and adventure makes it a standout choice for those looking to create unforgettable memories in San Diego.

Where to stay near Otay Mesa

Otay Mesa offers a delightful mix of family-friendly attractions and vibrant cultural experiences. Visitors can explore the Otay Town Center Mall for shopping and dining, or venture to nearby Mission Bay for scenic views and outdoor activities. With its friendly atmosphere and proximity to diverse neighborhoods like Point Loma, Otay Mesa is a perfect base for a memorable vacation, catering to families, couples, and budget travelers alike.

  • San Diego: San Diego is a vibrant city that embodies the quintessential Southern California lifestyle. Located adjacent to Otay Mesa, it offers a mix of family-friendly activities, outdoor adventures, and stunning beaches. Visitors can explore renowned attractions like theme parks and family beaches, making it an ideal destination for all ages. The city is known for its pleasant climate year-round, with peak travel times in March to April and July, ensuring a lively atmosphere for tourists. Don't miss out on the diverse shopping centers and malls that add to the San Diego experience.
  • San Ysidro: Just 6.4km away from Otay Mesa, San Ysidro is a bustling city known for its shopping and cultural experiences. Travelers flock here for both family-oriented and business-themed activities, especially during peak months like June to July and November. The city features popular shopping centers and a water park, making it a fun spot for families. Additionally, local attractions like theme parks and symbolic landmarks offer visitors a taste of the area's rich culture. San Ysidro’s proximity to the border with Mexico also allows for unique cross-cultural experiences.
  • South Bay: Located 8.0km from Otay Mesa, South Bay is a delightful area perfect for outdoor enthusiasts and families alike. With peak travel seasons occurring from June to August, visitors can enjoy the sun-soaked beaches and amusement parks. South Bay is characterized by its beautiful bay views and vibrant beach culture. The area is home to several shopping centers and local attractions, including theme parks, making it a well-rounded destination for a fun-filled vacation. South Bay’s inviting atmosphere and access to outdoor activities make it a must-visit during your stay.

Things to do near Otay Mesa

Otay Mesa offers a fantastic blend of family-friendly activities and entertainment options, making it an ideal vacation spot. Visitors can enjoy a variety of attractions, including shopping centers and theaters. Exciting activities such as arcade fun, family outings, and a water park promise memorable experiences, while events like Comic-Con add to the vibrant atmosphere. Whether you're seeking adventure or relaxation, Otay Mesa has something for everyone.

Shopping

For shopping in Otay Mesa, explore Las Americas Premium Outlets and Otay Ranch Town Center, both 6.4km away, offering a mix of family-friendly and business vibes. Chula Vista Center, 12.9km away, also provides a lively atmosphere with various entertainment options.

Recreation

The Chula Vista Elite Athlete Training Center offers a vibrant sports atmosphere with top-notch facilities, perfect for fitness enthusiasts. Eastlake Country Club provides a relaxing outdoor golf experience amidst lush landscapes. For luxury and wellness, the Salvation Army Kroc Center features upscale amenities and various recreational activities.

Adventure

Experience a splashing good time at Sesame Place San Diego, a vibrant waterpark 4.8km from Otay Mesa, perfect for family fun. For a thrilling indoor adventure, visit Sky Zone San Diego Indoor Trampoline Park, located 11.3km away, where you can bounce to your heart's content.

Enjoy the excitement at White Water Canyon, another waterpark situated 4.8km from Otay Mesa, offering entertainment and adventure vibes for the whole family.

Nightlife

The nightlife in Otay Mesa offers a mix of entertainment and adventure. Catch a concert at North Island Credit Union Amphitheatre, just 4.8km away, or enjoy family fun at Len Moore Skate Park and Atlantis Laser Tag, both within a short drive, perfect for an exciting evening out.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Otay Mesa

To save money during your trip to Otay Mesa, consider visiting from November to January when hotel prices drop. Tuesdays are the cheapest days to stay, while Saturdays are the most expensive. Use Expedia to compare hotel prices and filter for eco-friendly options. You can also save by booking a hotel package that includes flights and activities. For transportation, utilize local public transit options to keep costs low. Explore free attractions in the area to enhance your experience without breaking the bank.

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay around Otay Mesa are November to January, where the prices are slightly lower. This is in comparison to June to August, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay around Otay Mesa is Tuesday. The most expensive day to stay around Otay Mesa is Saturday.
  • Find cheap hotels on Expedia: Expedia’s search tool enables you to customize your travel preferences, including your budget and desired location. You can easily sort the results from lowest to highest price, allowing you to view the most affordable hotel options first. Additionally, you have the ability to refine your search by hotel category; for instance, selecting the Eco-certified filter will showcase sustainable and environmentally-friendly hotels that are available for booking.
  • Consider bundling your trip: You can save money by combining your Otay Mesa hotel reservation with your flights and activities through an Expedia package.

Find the best attractions near Otay Mesa

Otay Mesa is an ideal destination for family-friendly and entertainment-focused vacations. Visitors can explore a variety of attractions including beautiful beaches, urban parks, and event venues. Whether you're seeking cultural experiences or outdoor adventures, Otay Mesa offers a range of points of interest that cater to families and travelers looking for memorable experiences in this vibrant area of San Diego.

  • San Ysidro Border Crossing: Experience the vibrant atmosphere at one of the busiest border crossings in the world. Just 4.8km from Otay Mesa, it offers a unique glimpse into cultural exchanges, with friendly locals and a sunny vibe perfect for family outings.
  • San Diego Convention Center: Located 24.1km away, this premier event venue hosts various conferences and conventions. Its modern architecture and lively business atmosphere make it an exciting stop for networking and entertainment.
  • Coronado Beach: Also 24.1km from Otay Mesa, this stunning beach is known for its golden sands and relaxed beach vibes. It's ideal for sunbathing, swimming, and enjoying breathtaking ocean views.

Best time to go to Otay Mesa

The best time to visit Otay Mesa is dependent on what kind of holiday you are seeking. August is its hottest month on average. At this time, visitor numbers are average and weather is sunny with no rain. February is its coolest month on average. At this time, visitor numbers are average and weather is sunny with light rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January57.4°F (14.1°C)Light RainSunnySlightly LowSlightly Low
February56.8°F (13.8°C)Light RainSunnyAverageAverage
March58.1°F (14.5°C)No RainMostly SunnyAverageAverage
April60.6°F (15.9°C)No RainSunnyAverageAverage
May62.6°F (17.0°C)No RainSunnyAverageAverage
June66.4°F (19.1°C)No RainSunnySlightly HighSlightly High
July70.5°F (21.4°C)No RainSunnySlightly HighSlightly High
August72.3°F (22.4°C)No RainSunnyAverageSlightly High
September72.0°F (22.2°C)No RainSunnySlightly HighAverage
October68.2°F (20.1°C)No RainSunnySlightly LowAverage
November62.6°F (17.0°C)No RainSunnyAverageSlightly Low
December57.4°F (14.1°C)Light RainMostly SunnySlightly LowSlightly Low

The nearest major airports for your trip to Otay Mesa

When visiting Otay Mesa, you have convenient access to two major airports. San Diego International Airport (SAN) is located 29.0km away, with notable hotels nearby such as the 5-star Pendry San Diego and The US Grant, both within 4.8km, and The Lodge at Torrey Pines, 19.3km away. Tijuana's General Abelardo L. Rodriguez International Airport (TIJ) is even closer, just 1.4km from Otay Mesa, offering options like the 4.5-star Quartz Hotel & SPA and Real Inn Tijuana, both 4.8km away. Additionally, Carlsbad's McClellan-Palomar Airport (CLD) is 44.8km from Otay Mesa, with luxurious stays such as the Park Hyatt Aviara Resort nearby.

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Frequently asked questions

What's it like in Otay Mesa?
Otay Mesa is a neighborhood that travelers like for its beaches, restaurants, and shopping.
Where is the best hotel for a stay in Otay Mesa?
Based on Expedia customer reviews, Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG is the highest ranked property in Otay Mesa. This hotel offers free breakfast and an outdoor pool. Another top choice in the area is Quality Suites San Diego Otay Mesa.
If I need to cancel my hotel reservation in Otay Mesa, will I receive a refund?
Yes! The majority of hotel reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a non-refundable reservation, you might still have the option to cancel and receive a refund within a 24-hour period of booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to view the best deals available in Otay Mesa.
Where can I learn more about changing or cancelling my trip to Otay Mesa?
To find more details about changing or cancelling your trip to Otay Mesa, go to https://www.expedia.com/service/.
What is there to do in this San Diego neighborhood?
A few places to visit in the area around Otay Mesa include High Performance Center in Tijuana, Parque Industrial FINSA Tijuana, and Otay Sports Fields. While you're out sightseeing, Caliente Casino and Alameda Otay are a couple of additional sights to visit in San Diego.