Find all hotels by Best Western in Otay Mesa West, CA from AED 304
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for Otay Mesa West Best Western
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
Mission Valley
8.0 out of 10, Very Good, (2305)
"It was a good family hotel. "
Jurida
The price is AED 436
AED 501 total
includes taxes & fees
15 Dec - 16 Dec
Best Western Seven Seas
Mission Valley
7.8 out of 10, Good, (3048)
"In spite of the construction, we enjoyed our short stay and will come again!"
Patricia
The price is AED 272
AED 313 total
includes taxes & fees
10 Dec - 11 Dec
Best Western Chula Vista/Otay Valley Hotel
Otay
7.8 out of 10, Good, (1531)
"Great place to stay, staff was fantastic "
Pamela
The price is AED 372
AED 409 total
includes taxes & fees
15 Dec - 16 Dec
Best Western Americana Inn
San Ysidro
9.0 out of 10, Wonderful, (1190)
"Amazing time at this place "
Maria de Los Angeles
The price is AED 372
AED 423 total
includes taxes & fees
4 Jan - 5 January 2026
Best Western Yacht Harbor Hotel
Point Loma
8.6 out of 10, Excellent, (1629)
"The breakfast options were good and the staff were very helpful."
Gail or Rob
The price is AED 360
AED 413 total
includes taxes & fees
10 Dec - 11 Dec
Best Western San Diego Pacific Beach/Mission Bay
Bay Park
8.2 out of 10, Very Good, (186)
"Great stay, the staff was very friendly! "
frances
The price is AED 265
AED 304 total
includes taxes & fees
16 Dec - 17 Dec
Best Western Santee Lodge
Santee
7.8 out of 10, Good, (586)
" Room was clean and the staff was friendly"
Daniel
The price is AED 380
AED 419 total
includes taxes & fees
14 Dec - 15 Dec
Best Western Downtown San Diego
Downtown San Diego
8.4 out of 10, Very Good, (922)
"Staff was exceptionally helpful and the room was very clean. Will definitely stay here again!"
Blanca
The price is AED 450
AED 512 total
includes taxes & fees
29 Dec - 30 Dec
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Top Otay Mesa West Hotel Reviews
Comfort Inn San Diego Airport At The Harbor
10/10 Excellent
Explore a world of travel with Expedia
Otay Mesa West Hotels by Brand
Hotels in Otay Mesa West Neighborhoods
Hotels near popular San Diego Attractions
More Accommodation Types in Otay Mesa West
Explore more hotels
- Hilton San Diego Mission Valley
- Wyndham San Diego Bayside
- Courtyard by Marriott San Diego Downtown Little Italy
- The Dana on Mission Bay
- Kings Inn San Diego
- Hotel del Coronado, Curio Collection by Hilton
- The Sofia Hotel
- Comfort Inn San Diego Airport At The Harbor
- Pendry San Diego
- The Bristol Hotel San Diego
- Days Inn by Wyndham San Diego Hotel Circle
- Marriott Marquis San Diego Marina
- Margaritaville Hotel San Diego Gaslamp Quarter
- DoubleTree by Hilton San Diego - Hotel Circle
- GreenTree Inn San Diego Mission Bay
- California Suites Hotel
- Wyndham Garden San Diego Near SeaWorld
- Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
- Sentral Gaslamp Quarter
- Embassy Suites by Hilton San Diego Bay Downtown