Find 2 Star Hotels in Southeast Missouri, MO from AED 208
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Compare Southeast Missouri 2 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Baymont Inn and Suites by Wyndham Farmington, MO
Farmington
8.0 out of 10, Very Good, (1004)
The price is AED 197
AED 224 total
includes taxes & fees
30 Nov - 1 Dec

Motel 6 Poplar Bluff, MO
Poplar Bluff
7.8 out of 10, Good, (1006)
The price is AED 279
AED 294 total
includes taxes & fees
17 Nov - 18 Nov

The Farmstead Hotel
Caruthersville
8.8 out of 10, Excellent, (444)
The price is AED 314
AED 357 total
includes taxes & fees
26 Nov - 27 Nov

Fairfield Inn & Suites by Marriott Poplar Bluff
Poplar Bluff
9.4 out of 10, Exceptional, (837)
The price is AED 382
AED 432 total
includes taxes & fees
1 Dec - 2 Dec

Pear Tree Inn Cape Girardeau West
Cape Girardeau
9.0 out of 10, Wonderful, (1001)
The price is AED 257
AED 290 total
includes taxes & fees
19 Nov - 20 Nov

Pear Tree Inn Cape Girardeau Near the Medical Center
Cape Girardeau
9.0 out of 10, Wonderful, (1001)
The price is AED 257
AED 290 total
includes taxes & fees
19 Nov - 20 Nov

Hampton Inn Sikeston
Sikeston
8.8 out of 10, Excellent, (423)
The price is AED 350
AED 396 total
includes taxes & fees
21 Nov - 22 Nov

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau
9.4 out of 10, Exceptional, (1001)
The price is AED 334
AED 377 total
includes taxes & fees
30 Nov - 1 Dec
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Explore similar 3-star hotels
Many 3-star hotels have the same amenities as 2-star hotels. See all 3-star hotels in Southeast Missouri.

Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive, Cape Girardeau, MO
The price is AED 331 per night from Dec 1 to Dec 2
AED 331
AED 373 total
1 Dec - 2 Dec
includes taxes & fees
9.4/10 Exceptional! (1,006 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Southeast Missouri
Explore the family-friendly area of Southeast Missouri—restaurants, wineries, and sights from Sam A. Baker State Park to K Bridge Recreation Area.

Photo by Bill Dillard
Open Photo by Bill Dillard
Top Southeast Missouri Hotel Reviews

Motel 6 Poplar Bluff, MO
10/10 Excellent

Days Inn and Suites by Wyndham Sikeston
10/10 Excellent
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Southeast Missouri Hotels by Star Rating
Hotels in Southeast Missouri Neighborhoods
Stay near popular Southeast Missouri attractions
- Hotels near Southeast Missouri State University
- Hotels near Elephant Rocks State Park
- Hotels near Ozark National Scenic Riverways
- Hotels near Johnson's Shut-ins State Park
- Hotels near Century Casino Caruthersville
- Hotels near Isle Casino Cape Girardeau
- Hotels near Echo Bluff State Park
- Hotels near Lake Wappapello
- Hotels near Taum Sauk Mountain State Park
- Hotels near Alley Spring & Mill
- Hotels near National Shrine of Our Lady of the Miraculous Medal
- Hotels near Rocky Falls
- Hotels near Sainte Genevieve Winery
- Hotels near Riverfront Park
- Hotels near Current River State Park
- Hotels near Bonne Terre Mine
- Hotels near Akers Ferry
- Hotels near Big Spring
- Hotels near Hawn State Park
More Hotel Options in Southeast Missouri
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More Accommodation Types in Southeast Missouri
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Explore more hotels
- Tru By Hilton Cape Girardeau
- Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
- Days Inn and Suites by Wyndham Sikeston
- Courtyard by Marriott Cape Girardeau Downtown
- Fairfield Inn & Suites by Marriott Poplar Bluff
- Silo Farm Haus- located in the heart of wine country!
- Drury Inn & Suites Cape Girardeau
- Candlewood Suites Cape Girardeau by IHG
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- La Quinta Inn & Suites by Wyndham Festus - St. Louis South
- Quality Inn
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- Hampton Inn Sikeston
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- Hampton Inn Poplar Bluff
- Hampton Inn Cape Girardeau I 55 East
- Holiday Inn Express & Suites Perryville by IHG
- Super 8 by Wyndham Farmington
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