Photo by Henry Fitzthum

Find 2 Star Hotels in Southeast Missouri, MO from AED 220
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Our top choices for Southeast Missouri 2-star hotels

Baymont Inn and Suites by Wyndham Farmington, MO
Baymont Inn and Suites by Wyndham Farmington, MOFarmington
8.0 out of 10, Very Good, (1,004 reviews)
The price is AED 194
AED 221 total
includes taxes & fees
25 Jan - 26 Jan
The price is AED 209
AED 221 total
includes taxes & fees
20 Jan - 21 Jan

7.2 out of 10, Good, (1,001 reviews)
The price is AED 231
AED 263 total
includes taxes & fees
20 Jan - 21 Jan

9.0 out of 10, Wonderful, (1,000 reviews)
The price is AED 257
AED 293 total
includes taxes & fees
22 Jan - 23 Jan

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
9.4 out of 10, Exceptional, (1,003 reviews)
The price is AED 334
AED 377 total
includes taxes & fees
25 Jan - 26 Jan

Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (866 reviews)
The price is AED 381
AED 430 total
includes taxes & fees
31 Jan - 1 Feb
The price is AED 279
AED 317 total
includes taxes & fees
30 Jan - 31 Jan

Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau Near the Medical CenterCape Girardeau
9.0 out of 10, Wonderful, (1,003 reviews)
The price is AED 382
AED 431 total
includes taxes & fees
18 Jan - 19 Jan
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Explore similar 3-star hotels
Many 3-star hotels have the same amenities as 2-star hotels. See all 3-star hotels in Southeast Missouri.

Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive Cape Girardeau MO
The price is AED 331 per night from Jan 22 to Jan 23
AED 331
AED 373 total
22 Jan - 23 Jan
includes taxes & fees
9.4/10 Exceptional! (1,007 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Southeast Missouri
Explore the family-friendly area of Southeast Missouri—restaurants, wineries, and sights from K Bridge Recreation Area to Lake Wappapello State Park.

Photo by Bill Dillard
Open Photo by Bill Dillard
Top Southeast Missouri Hotel Reviews

Motel 6 Poplar Bluff, MO
10/10 Excellent
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Hotels in Southeast Missouri Neighborhoods
Stay near popular Southeast Missouri attractions
- Hotels near Johnson's Shut-ins State Park
- Hotels near Southeast Missouri State University
- Hotels near Ozark National Scenic Riverways
- Hotels near Elephant Rocks State Park
- Hotels near Century Casino Caruthersville
- Hotels near Isle Casino Cape Girardeau
- Hotels near Bonne Terre Mine
- Hotels near Lake Wappapello
- Hotels near Taum Sauk Mountain State Park
- Hotels near Current River State Park
- Hotels near Alley Spring & Mill
- Hotels near Echo Bluff State Park
- Hotels near Akers Ferry
- Hotels near Sainte Genevieve Winery
- Hotels near Hawn State Park
- Hotels near Riverfront Bridge Park
- Hotels near Hunter Valley Winery
- Hotels near Riverfront Park
- Hotels near Big Spring
More Hotel Options in Southeast Missouri
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More Accommodation Types in Southeast Missouri
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Explore more hotels
- Drury Inn & Suites Jackson MO
- Silo Farm Haus- located in the heart of wine country!
- Candlewood Suites Cape Girardeau by IHG
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- Holiday Inn Poplar Bluff by IHG
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